<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation V82A
Rx >= 1 PI
IncludeMixtures No
References 18
Patients 53
Isolates 59
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Snoeck (2002)BE16aBE16aAF339009IDV107M46I, V82AL24IL10IM, T12TS, I15V, L19T, M36I, R41K, K43KN, R57RS, D60E, Q61E, L63P, H69K, L89M, I93LC
Johnston (2003)TC-60TC-60 IDV104I54IV, V82A I15V, E35D, M36I, R41K, L63P, H69K, A71AT, I93LC
 TC-71TC-71 IDV52G48V, I54T, V82A L10I, I15V, L19I, K20R, E35D, M36I, R41K, L63V, H69K, A71V, T74S, L89M, I93LC
Weber (2003)85H610185H-48AY140823RTV48I54V, V82A L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69R, T74S, V77I, L89M, I93LC
Grossman (2004)IL384IL384aAY529618IDV, SQV, RTV, NFV154M46I, I54V, V82A, L90MT74PW6WL, L10V, I15V, K20KI, M36I, N37D, R41K, L63P, H69K, A71V, L89M, I93LC
  IL384bAY529622IDV, SQV, RTV, NFV239M46I, I54V, V82A, L90MT74PL10V, I15V, M36I, N37D, R41K, K55R, I62V, L63P, H69K, A71V, L89M, I93LC
 IL433IL433aAY529600IDV117M46ML, V82A, L90LMQ58EL10C, I15V, K20R, M36I, K45KR, L63T, H69K, L89M, I93LC
  IL433bAY529601IDV174M46L, V82A, L90LML10F, Q58QEI15V, K20R, M36I, L63PT, H69K, L89M, I93LC
Snoeck (2004)BE59BE59AY900757SQV, IDV, RTV, NFV217G48V, I54A, V82AL33F, K43KTL10I, I13V, I15V, L19I, M36L, N37EQ, L38M, I62V, L63V, H69K, I72V, T74S, L89LI, I93LC
Non-B Workgroup (2005)UK162UK162AY900762RTV57M46I, V82A, L90MK43TT12S, I15V, L19I, K20R, D25E, M36I, R41K, K55R, Q61E, I62V, L63V, H69K, T74S, L89M, I93LC
 UK1447UK1447AY900803IDV, SQV, RTV83G48GA, I54V, V82A, I84V, L90ML23LI, K43KTL10Y, I15V, M36I, R41K, I62V, L63V, H69K, A71V, T74S, L89LM, I93LC
 IL80IL80AY900811RTV, NFV, SQV114I54V, V82A, I84VK43TW6WL, T12S, L19I, K20R, E21EG, M36I, G40E, R41K, L63P, H69K, A71V, T74A, I93LC
 IL257IL257AY900818IDV, RTV110V82A L10I, I15V, L19I, D29DV, M36I, R41K, L63P, H69K, I85V, I93LC
 UK1447bUK1447bAY900833IDV, NFV, SQV, RTV, APV, LPV175M46I, I50V, I54V, V82A, L90ML10F, L23I, K43TI15V, K20R, E35D, M36I, R41K, I62V, L63V, H69K, A71V, T74S, L89I, I93LC
 TK1002TK1002 RTV225M46I, I54V, V82A L10V, T12S, K14KR, I15V, L19I, K20R, M36I, R41K, Q61H, L63V, H69K, K70KR, T74S, L89M, I93LC
 TK1021TK1021 IDV, RTV, LPV331M46I, I54V, V82AL10F, L24I, Q58ET12S, L19I, E35D, M36I, N37D, R41K, K55R, D60E, Q61E, I62V, L63P, H69K, L89M, I93LC
 TK3015TK3015 SQV, IDV204I54V, V82A, L90MK43TL10I, T12S, I15V, L19I, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93LC
  TK3015a SQV, IDV, LPV264I54V, V82A, L90ML10F, K43TT12S, I15V, L19K, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93LC
  TK3015b SQV, IDV, LPV283I54V, V82A, L90ML10F, K43TT12P, I15V, L19K, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93LC
 TK3035TK3035 IDV, NFV, RTV202I54A, V82A L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K45KR, D60E, L63P, H69K, A71V, L89M, I93LC
 TK4011TK4011 SQV, RTV, NFV, IDV261V82A, L90MQ58E, G73SL10V, T12S, I15V, L19I, K20R, M36I, L63P, H69K, A71V, I72L, I93LC
 K5009TK5009 RTV, IDV96M46I, L76V, V82AL10LFT12S, I15V, L19I, K20KR, M36I, R41K, I62V, L63P, H69K, L89M, I93LC
 PL3670560970 IDV98V82A, L90LMT74PL10I, T12TS, I15V, L19I, K20KR, M36I, N37NS, R41K, K45R, Q61N, L63S, H69K, I72V, L89M, I93LC
 PL4205672786 IDV, RTV275V82AL10F, L24I, I54CT12TS, I13IV, G17D, L19I, K20R, M36I, R41K, K45R, L63P, H69K, A71V, L89I, I93LC
  91776 IDV, RTV, LPV340V82AL10F, L24I, I54CG17D, L19I, K20R, M36I, R41K, K45R, L63P, H69K, A71V, L89I, I93LC
 PL833877353 IDV, RTV304I54V, V82A L10I, I13IV, I15V, L19I, M36L, R41K, I62V, L63P, I64V, H69K, L89M, I93L, C95FC
Weber (2005)F30356F30356AY677479Unknown, NFV>201I54V, V82A, L90M L10I, T12S, I15V, L19T, K20R, E35D, M36I, N37H, P39PS, R41K, K45R, L63P, H69KQ, A71I, I93LC
Baxter (2006)12-10071007-30519DQ875953PINAM46L, I54IV, V82A, L90ML33F, K43KTL10I, I15V, L19T, K20R, E35D, M36I, R41K, Q61E, I62IV, L63P, H69K, T74S, L89M, I93LC
 12-30493049-30508DQ876115PINAM46I, I54V, L76V, V82A, L90ML10FIW6W*, I15V, L19T, K20I, E35DN, M36I, R41K, Q61H, L63P, H69K, A71V, T74S, I85V, L89I, T91S, I93LC
 12-17161716-30421DQ876854PINAM46L, I54V, V82A, I84VL24I, L33F, K43TL10I, I15V, K20R, E35D, M36I, N37ND, R41K, I62V, L63T, H69K, T74S, L89M, I93LC
 48-14071407-30410DQ877803PINAI54V, V82A, L90ML10FI, K43TT12PS, I15V, L19IK, K20I, E35D, M36I, R41K, D60E, Q61E, I62IV, L63P, H69K, A71V, I85V, I93LC
 48-24052405-30826DQ877890PINAM46I, V82AL10F, K43T, T74PT12S, I15V, L19T, K20R, M36I, Q61E, I62V, L63P, H69K, L89M, I93LC
 48-30583058-30401DQ877970PINAI54L, V82A, L90ML33F, K43KTL10I, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63P, H69K, T74S, L89M, I93LC
 48-32293229-30523DQ878136PINAM46I, I54V, V82A, I84VL10F, L24I, L33F, K43TT12S, I13V, L19I, K20M, E35D, M36I, R41K, L63V, I64V, H69K, T74S, L89I, T91SC
 48-41344134-30317DQ878365PINAG48V, I54V, V82A, I84VL33F, K43TL10I, I15V, G16E, L19I, K20V, E35DN, M36I, L63C, H69K, T74S, I85V, L89M, I93LC
 48-50015001-30415DQ878534PINAM46I, L76V, V82AL10F, L33LFI13IV, I15V, G16A, L19I, E34EQ, M36L, N37S, R41K_K, G51A, K55N, I62V, H69K, T74S, L89I, I93ILC
 48-50965096-30901DQ878592PINAM46I, I54V, V82A, L90MK43KT, T74PL10V, I13A, K20IM, E21K, A22V, M36I, R41RK, K55R, Q61N, L63P, I64V, H69K, L89M, I93LC
 48-71017101-30723DQ878954PINAM46I, I54V, V82AL10F, L24IT12P, I13V, L19I, K20I, E35D, M36I, R41K, L63P, H69K, T74AS, L89M, I93LC
 48-93029302-30918DQ877587PINAI54V, V82A, L90ML10F, G73GS, L89IMVI15V, K20I, E35D, M36I, N37K, R41N, Q61H, L63P, H69K, A71V, I85V, I93LC
Sanabani (2006)04BR01304BR013AY727522PINAM46I, G48V, V82AL24IL10I, K20R, M36I, N37E, R41K, K55R, I62V, L63P, H69K, T74A, L89M, I93LC
Sen (2007)T076NPT76EF186928NFV, RTV M46L, V82A, L90MT74PL10V, T12A, I15V, L19I, K20R, M36I, N37D, K55N, L63P, H69K, A71V, I93LC
 T002NPT2-PLEF186983RTV, IDV M46I, I54V, V82AL24IL10I, T12S, I15V, L19I, M36L, N37S, R41K, Q61H, L63P, H69K, A71AV, L89M, I93LC
Marconi (2008)SW070SW070EU308081LPV49I54V, V82AL33LFG16A, L19V, E35D, M36I, R41K, I62V, L63P, H69K, T74S, L89M, I93LC
 SW083sw083EU308093LPV91V82A T12S, I15V, L19I, K20R, M36I, R41K, L63P, H69K, L89M, I93LC
Pillay (2008)DR44DR44AY589899RTV M46I, I54V, V82A L10I, I15V, L19I, K20R, M36I, N37S, H69K, L89M, I93LC
 DR55DR55AY589908RTV104M46L, I54V, V82AL23LIT12S, I15V, G16GE, L19I, K20R, M36I, R41K, L63V, H69K, T74S, L89M, I93LC
 DR68DR68AY589917RTV104M46I, I54V, V82A L10V, T12S, I15V, L19I, E35ED, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93LC
 DR71DR71AY589920RTV43V32VI, V82AM46MVI15IV, G16E, L19I, M36I, R41K, Q61H, L63A, E65D, H69K, I72V, L89M, I93LC
 DR9203ZA.DR92AY589931IDV, LPV V82A, L90M T12S, I13IV, I15V, L19IT, K20R, M36I, L38LV, R41K, D60E, Q61E, I62IV, L63P, H69K, L89M, I93LC
 DR10003ZA.DR100AY589936RTV M46I, I54V, V82A I15E, G16GE, L19E, K20R, E35D, M36I, R41K, H69K, L89I, I93LC
Rosen-Zvi (2008)7109p71-3 LPV175I54V, V82A I15V, Q18E, K20R, E35D, M36I, R41K, K45I, D60E, I62V, L63V, H69K, L89M, I93LC
Kandathil (2009)VL07_103VL07_103EU781835PINAM46I, I54V, V82AL24IL10I, T12S, I15V, L19T, M36I, R41K, L63P, H69K, L89M, I93LC
Dau (2010)06552A06552AGU581760PINAM46I, I54V, L76V, V82A L10I, I13V, G16GE, L19I, K20R, M36I, N37ND, R41K, Q61N, L63PS, H69K, T74S, L89M, I93LC
Knops (2010)ID2137ID2137-GT1GU271172IDV, LPV V32I, I47A, V82A L10I, T12S, I15V, L19AP, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93LC
  ID2137-GT2GU271173IDV, LPV, DRV, RTV33V32I, I54L, L76V, V82AL89VL5F, L10I, T12S, I15V, L19T, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93LC
Green (2011)707PKE19F707PKE19FHM623509RTV, LPV131M46I, I54V, L76V, V82AQ58EL10I, T12S, I15V, L19T, K20R, E35D, M36I, R41K, I62V, L63P, H69K, L89M, I93LC
Barber (2012)6957669576JQ361677LPV I54V, V82AL10FT12S, I15V, L19I, M36I, R41K, L63T, H69K, L89M, I93LC
 6599465994JQ361682LPV M46MI, I54V, V82A L10I, T12S, I15V, L19V, M36I, R41K, K45KR, L63P, H69K, T74S, I93LC
 5657256572JQ361684LPV V82AL10FI15V, G17D, L19I, M36I, D60E, L63P, H69K, L89M, I93LC

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