<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation T74A
Rx PI-naive
IncludeMixtures No
References 60
Patients 159
Isolates 159
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Novitsky (2002)00BW192100BW1921AF443101None   T12S, I15V, L19I, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 00BW177300BW1773AF443095None   T12S, I15V, L19I, M36I, R41K, L63S, H69K, T74A, L89M, I93LC
Papathanasopoulos (2002)99ZACM999ZACM9AF411967None   T12S, I15V, L19I, M36I, R41K, H69K, T74A, L89M, I93LC
Jorgensen (2003)JLB_Pat72HIM419498AJ419498None   I15V, K20R, M36I, N37K, R41N, R57K, L63T, H69K, T74A, L89M, I93LC
Maljkovic (2003)MI_Pat5200SE18474AY165224None   T12S, I15V, L19I, M36I, N37D, H69K, T74A, L89M, I93LC
Arroyo (2004)01TZA30101TZA301AY253312None   L19I, M36I, N37T, R41K, I62V, L63P, H69K, T74A, L89M, I93LC
 01TZA38801TZA388AY253317None   T12S, I15V, L19I, M36I, R41K, H69K, T74A, L89M, I93LC
Deshpande (2004)in77in77AY515790None   T12PS, I15V, L19I, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
Balakrishnan (2005)YRG14YRG14AY787500None   T12P, K14R, I15V, M36I, L63P, H69K, T74A, L89M, I93LC
Bussmann (2005)01BW2796S01BW2796SAY829296None   T12S, I15V, L19I, M36I, R41K, K43R, L63T, H69K, T74A, L89M, I93LC
 01BW2065S01BW2065SAY829287None   T12S, I15V, L19I, M36I, R41K, Q61E, H69K, T74A, L89M, I93LC
Non-B Workgroup (2005)UK2143UK2143AY900853None   I15V, L19I, M36I, N37D, H69K, T74A, L89M, I93LC
 UK2148UK2148AY900858None  Q58ET12S, I15V, L19I, K20R, M36I, N37D, R41K, D60E, L63AT, H69K, T74A, L89M, I93LC
Bessong (2006)POB_01PB16ZA01PB16ZADQ222248None   T12S, I15V, G16E, L19I, M36T, N37T, P39S, R41K, D60E, Q61E, L63S, H69K, T74A, L89M, I93LC
Rousseau (2006)Pt8903SK029B2AY772691None   L10M, I13V, K14R, L19I, M36I, R41K, I62V, L63V, H69K, T74A, L89M, I93LC
Razafindratsimandresy (2007)99HIV-SEYEF143501None   T12S, I15V, L19I, M36I, R41K, L63P, H69K, T74A, L89M, I93LC
 3838HIV-SEYEF143529None   T12S, I15V, L19T, E35D, N37S, R41K, R57K, L63P, H69K, T74A, V77I, L89M, I93LC
Vidal (2007)U081302BU.U0813AM260296None   T12S, I15V, L19T, M36I, N37S, R41K, H69K, T74A, L89M, I93LC
Arora (2008)16PI-16 None   T12S, K14R, L19T, E35D, N37D, R41K, L63P, H69K, K70R, T74A, L89M, I93LC
Deho (2008)127127EU244659None   L10M, T12S, I15V, L19I, M36I, R41K, D60E, Q61E, I62V, L63I, H69K, T74A, L89M, I93LC
 130130EU244671None   I15V, M36I, R41K, H69K, T74A, L89M, I93LC
Ferreira (2008)430BR05PR430EU340715None   L10M, I15V, E35D, N37K, R41N, I62V, L63I, H69K, T74A, L89M, I93LC
Jacobs (2008)17681768EF602209None   I15V, L19T, M36I, R41K, H69K, T74A, L89M, I93LC
 16711671EF602271None   T12S, I15V, L19I, M36I, R41K, L63P, H69K, T74A, L89M, I93LC
Kamoto (2008)MW41MW41JQ617157None   I15V, L19I, M36I, R41K, L63S, H69K, T74A, L89M, I93LC
Lahuerta (2008)P348434p348434_04EF407714None   T12S, I15V, L19I, M36I, R41K, H69K, T74A, L89M, I93LC
 P64695P64695_99EF407740None   T12S, I15V, L19I, N37S, R41K, H69K, T74A, V77I, L89M, I93LC
Marconi (2008)SW006sw006EU308024None   I15V, L19I, M36I, R41K, Q61H, H69K, T74A, L89M, I93LC
Matthews (2008)PS207PS207FJ199763None   T12S, I15V, L19I, M36I, R41K, H69K, T74A, L89M, I93LC
 PS367PS367FJ199786None   T12S, I15V, L19V, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 SK029SK029FJ199858None   L10M, I13V, K14R, L19I, M36I, R41K, I62V, L63V, H69K, T74A, L89M, I93LC
Rosen-Zvi (2008)7105p71-1 None   I15V, Q18E, K20R, E35D, M36I, R41K, D60E, Q61E, I62V, L63V, H69K, T74A, L89M, I93LC
Hosseinipour (2009)72947294GQ228206None   I15V, L19IV, M36I, R41K, Q61E, I62IV, H69K, T74A, L89M, I93LC
 94029402GQ228241None   L10I, T12S, I15V, L19I, M36I, R41K, R57K, Q61E, I62V, L63V, E65D, H69K, T74A, L89MC
 93269326GQ228256None   L10I, K14R, I15V, L19I, M36I, R41K, L63V, H69K, T74A, L76L*, L89M, I93LC
 93279327GQ228257None   T12S, I15V, L19I, M36I, R41K, L63P, H69K, T74A, L89M, I93LC
Kandathil (2009)VL07_231VL07_231EU683761None   T12S, I15V, L19I, M36L, R41K, K45R, L63T, H69K, T74A, L89M, I93LC
Vercauteren (2009)pt6858993553064GQ400339None   T12S, I15V, G16E, L19I, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 pt5609587387978GQ400464None   T12S, I15V, G17GD, L19I, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 pt416Eqo33oiOjFGQ400608None   T12LS, I15V, L19KT, E35D, M36I, R41K, D60E, H69K, T74A, L89M, I93LC
Wallis (2009)GT00032651GT00032651 None   L10I, T12S, K14I, I15V, L19IK, K20R, M36I, R41K, D60E, Q61QE, I62V, L63LI, H69K, T74A, L89M, I93LC
Chaturbhuj (2010)2-0192-019FJ878965None   T12S, I15V, L19I, M36I, R41K, L63A, H69K, K70R, T74A, L89M, I93LC
Gonzalez (2010)KT10KT10GQ433836None   T12S, I15V, L19I, M36I, R41K, L63V, H69K, T74A, L89M, I93LC
 1928_M00m1928_M00mGQ427137None   T12S, I15V, L19I, M36I, R41K, H69K, T74A, L89M, I93LC
Papathanasopoulos (2010)1698506ZA16985GU253404None   T12S, I15V, L19I, M36I, R41K, L63P, H69K, K70KR, T74A, L89M, I93LC
 1765707ZA17657GU253423None   T12S, I15V, L19V, N37S, R41K, L63A, H69K, T74A, L89M, I93LC
Wright (2010)187SK187HM593194None   T12S, L19I, R41K, C67CY, H69K, T74A, L89M, I93LC
 29SK29HM593292None   L19IT, K20KR, M36I, R41K, I62V, L63AV, H69K, T74A, L89M, I93LC
Bussmann (2011)B0679B0679JQ616990None   I15V, L19I, E35D, M36I, R41K, D60E, H69K, T74A, L89M, I93LC
 B0681B0681JQ616991None   I15V, L19I, E35D, M36I, R41K, D60E, H69K, T74A, L89M, I93LC
 B0688B0688JQ616995None   I15V, L19I, R41K, Q61E, H69K, T74A, V77I, L89M, I93LC
 B0555B0555JQ617050None   L19I, M36I, R41K, D60E, H69K, T74A, L89M, I93LC
 B0561B0561JQ617055None   I15V, L19V, N37S, R41K, H69K, T74A, V77I, L89M, I93LC
Deshpande (2011)Pat027in1105JF414443None   T12S, L19I, M36I, R41K, K43R, I62V, L63P, H69K, T74A, L89M, I93LC
Graf (2011)SC73SC73JF774026None   M36I, N37K, R41P, H69K, T74A, L89M, I93LC
Hamers (2011)300031CP076300031HM119625None   T12S, I15V, L19I, M36I, N37D, R41K, H69K, T74A, L89M, I93LC
 300032CP076300032HM119626None   T12S, I15V, L19T, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 300059CP076300059HM119648None   L10V, T12S, I15V, L19I, M36I, R41K, L63P, H69K, T74A, I93LC
 300139CP076300139HM119715None   I15V, L19I, M36I, R41K, H69K, T74A, L89M, I93LC
 300150CP076300150HM119726None   I15V, L19I, M36I, R41K, H69K, T74A, L89IM, I93LC
 300222CP076300222HM119790None   Q2S, T12S, I15V, L19I, M36I, R41K, L63T, H69K, I72IV, T74A, L89M, I93LC
 300274CP076300274HM119814None   Q7X, T12S, I15V, L19I, M36I, R41K, Q61E, I62V, L63P, H69K, T74A, L89M, I93LC
 300287CP076300287HM119820None   T12S, I15V, L19I, E35D, M36I, R41K, I62V, L63T, H69K, T74A, L89M, I93LC
 300419CP076300419HM119843None   T12P, I15V, L19V, M36I, R41K, H69K, T74A, L89M, I93LC
 300493CP076300493HM119912None  Q58EM36I, N37D, D60E, L63P, H69K, T74A, L89M, I93LC
 300510CP076300510HM119927None   T12S, K14R, I15V, L19T, K20R, E35D, M36I, N37D, R41K, L63T, H69K, T74A, L89LM, I93LC
 300515CP076300515HM119932None   T12S, I15V, L19I, M36I, R41K, Q61E, I62IV, L63P, H69K, T74A, V75I, L89M, I93LC
 300521CP076300521HM119938None   T12S, I15V, L19I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, T74A, L89M, I93LC
 300612CP076300612HM120013None   T12S, I15V, L19I, M36I, N37D, R41K, L63LV, H69K, T74A, L89M, I93LC
 300632CP076300632HM120029None   T12S, I15V, L19I, E35D, M36I, R41K, L63C, H69K, T74A, L89MC
 300668CP076300668HM120059None   T12TP, I15V, L19I, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 302397CP076302397HM120104None   I15V, L19LI, M36I, N37E, R41K, H69K, K70R, T74A, L89M, I93LC
 CP076301739CP076301739HQ993729None   T12S, I15V, G16A, L19I, E35D, M36I, N37K, R41N, R57K, D60E, H69K, T74A, L89M, I93LC
 CP076303193CP076303193HQ994205None   T12S, I15V, L19V, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 CP076303248CP076303248HQ994245None   T12S, I15V, L19V, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 CP076305034CP076305034HQ994279None   I15V, L19I, M36I, R41K, D60E, H69K, T74A, L89M, I93LC
 CP076305055CP076305055HQ994294None   Q7E, T12S, I15V, L19I, M36I, R41K, L63A, H69K, T74A, L89M, I93LC
 CP076301457CP076301457HQ994427None   T12S, L19V, E35D, N37E, Q61QE, L63P, H69K, T74A, L89M, I93LC
 CP076301496CP076301496HQ994450None   I15V, G16E, L19I, N37NS, R41K, H69K, T74A, V77I, L89M, I93LC
 CP076302182CP076302182HQ994527None   T12S, I15V, L19I, M36I, R41K, L63A, H69K, T74A, L89M, I93LC
 CP076300955CP076300955HQ994557None   T12S, I15V, L19LI, M36I, R41K, D60E, Q61E, H69K, T74A, L89M, I93LC
 CP076300965CP076300965HQ994731None   T12S, I15V, L19I, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 CP076300997CP076300997HQ994755None  Q58ET12S, I15V, L19I, E35D, M36I, N37D, R41K, R57K, L63P, C67CGW, H69K, T74A, R87RK, L89M, I93L, T96TPC
 CP076301008CP076301008HQ994760None   T12P, I15V, G16E, L19I, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 CP076301100CP076301100HQ994782None   T12TS, K14R, I15V, L19T, K20M, E35D, M36I, R41K, H69K, T74A, L89M, I93LC
 CP076302685CP076302685HQ994824None   T12S, I15V, L19I, E35D, M36I, R41K, L63A, H69K, T74A, L89M, I93LC
 CP076302705CP076302705HQ994843None   T12S, I15V, L19I, R41K, L63T, H69K, T74A, V77I, L89M, I93LC
 CP763A03367CP763A03367HQ994903None   T12S, I15V, G16E, L19I, K20M, E35D, M36I, R41K, K45KR, H69K, T74A, L89M, I93LC
 CP763A03368CP763A03368HQ994904None   I15V, L19I, M36I, N37E, R41K, L63V, H69K, T74A, L89M, I93LC
Kasang (2011)3264732647HM572411None   T12S, I15V, L19I, M36I, R41K, K45KR, L63T, H69K, T74A, L89M, I93LC
Manasa (2011)10061501006150JN665024None   T12P, L19I, N37C, R41K, I62V, L63P, H69K, T74A, V77I, L89M, I93LC
 10091321009132JN665031None   T12P, I15V, L19I, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
Nwobegahay (2011)BBVCT06ZABBVCT06ZAGU139580None   T12S, I15V, L19I, E35D, M36I, R41K, K45R, R57K, L63T, H69K, T74A, L89M, I93LC
 BBVCT38ZABBVCT38ZAGU139598None   T12S, I15V, L19V, R41K, L63P, H69K, T74A, L89M, I93LC
 BBVCT63ZABBVCT63ZAGU139611None   T12S, I15V, L19V, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
Sanabani (2011)BR2022BR2022JN692434None   I15V, E35D, N37K, R41N, L63P, H69K, T74A, V77I, L89M, I93LC
van Zyl (2011)A205A205JN638124None   I15V, L19T, M36I, R41K, D60E, L63P, H69K, T74A, L89M, I93LC
 A256A256JN638152None   T12S, I15V, L19I, K20R, M36I, R41K, R57K, I62V, L63T, E65D, H69K, T74A, L89M, I93LC
Wright (2011)AS3-0458B2AS3-0458B2HQ696811None   T12S, I15V, L19I, M36I, R41K, H69K, T74A, L89M, I93LC
 AS3-0458B7AS3-0458B7HQ696863None   T12S, I15V, L19I, E35D, M36I, R41K, R57RK, H69K, T74A, L89M, I93LC
De Gascun (2012)IRL03405IRL03405JN622892None   T12S, I15V, L19I, M36I, R41K, L63T, C67CF, H69K, T74A, L89M, I93LC
 IRL52732IRL52732JN622972None   T12S, I15V, L19V, M36I, R41K, K45R, H69K, T74A, L89M, I93LC
 IRL20744IRL20744JN622999None  Q58ET12P, L19I, M36T, R41K, I62V, L63PS, H69K, T74A, L89M, I93LC
 IRL72441IRL72441JN623037None   L10I, T12S, I15V, L19I, M36I, R41K, D60E, Q61N, L63T, C67S, H69K, T74A, L89M, I93LC
Hingankar (2012)IN-NARI-4-023IN-NARI-4-023JN314912None   K14KR, I15V, L19IT, M36I, R41K, I62V, H69K, T74A, L89M, I93LC
 IN-NARI-4-068IN-NARI-4-068JN314949None   T12S, I13V, I15V, L19T, K20I, M36I, R41K, L63LAPV, H69K, T74A, L89M, I93LC
Hunt (2012)KZN09_380166KZN09_380166KF736757None   T12S, I15V, L19I, M36I, N37D, R41K, L63T, H69K, T74A, L89M, I93LC
 GP08_3619GP08_3619KF736675None   T12S, I15V, L19I, M36I, R41K, D60E, L63V, H69K, T74A, L89M, I93LC
 KZN09_387143KZN09_387143KF736794None   T12S, I15V, L19I, M36I, R41K, L63V, H69K, T74A, L89M, I93LC
 GP06_191331GP06_191331KF736544None   T12S, I15V, L19I, M36I, R41K, Q61E, I62V, H69K, T74A, L89M, I93LC
Luebbert (2012)LEU 011870103562 None   I15V, L19I, M36I, N37D, R41K, H69K, T74AC
 LEU 011470102373 None   T12S, K14KN, I15V, L19T, E35D, M36I, N37D, L63T, H69K, T74AC
Nwobegahay (2012)MC30ZAMC30ZAGU177543None   I15V, L19V, N37S, D60E, L63P, H69K, T74A, V77I, L89M, I93LC
Sinha (2012)AIIMS-46AIIMS-46HQ453375None   T12S, I13V, I15ILV, L19I, M36I, R41K, K45R, Q61H, L63P, H69K, T74A, L89M, L90LS, I93LC
 AIIMS-59AIIMS-59HQ453382None   T12P, L19I, E35D, M36I, N37E, K45R, R57K, D60DE, I62IV, H69K, T74A, L89M, I93LC
Zeng (2012)CN1244CN1244JQ028391None   T12S, K14R, I15V, L19I, M36I, R41K, D60E, I62V, L63P, H69K, T74A, L89I, I93LC
Alencar (2013)MG2-0040MG2-0040JQ238210None   L10V, I15V, G16E, M36I, N37K, P39S, R41N, L63V, H69K, T74A, L89M, I93LC
Bila (2013)MZ10-202HIV-1KF927301None   T12S, I15V, L19I, M36I, R41K, H69K, T74A, L89M, I93LC
 MZ09-104HIV-1KF927233None   T12P, I15V, L19I, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
Chen (2013)11YNHH08611YNHH086JX412351None   T12S, I15V, L19I, M36I, R41K, D60E, L63V, H69K, T74A, L89M, I93LC
Frentz (2013)EHR-10493EHR-10493JX299706None   T12S, I15V, L19I, M36I, N37S, R41K, L63T, H69K, T74A, L89M, I93LC
 EHR-46976EHR-46976JX300325None   T12S, I15V, L19IT, R41K, D60E, Q61E, I62IV, H69K, T74A, L89M, I93LC
 EHR-54810EHR-54810JX300450None   T12S, I15V, L19I, M36I, R41K, I62IV, L63Q, H69K, T74A, L89M, I93LC
 EHR-65902EHR-65902JX300649None   T12S, I15V, L19I, M36I, R41K, I62V, L63I, H69K, T74A, V82I, L89M, I93LC
Hawke (2013)1393249913932499KC237933None   T12S, I15V, L19I, L23LF, E35D, M36I, N37ND, R41K, C67CF, H69K, T74A, L89M, I93LC
Kiertiburanakul (2013)X12025X12025KC994361None   T12P, G16E, L19I, D29DN, E35EK, M36I, G40GE, R41K, R57K, L63V, H69K, T74A, R87RK, L89M, I93LC
Mulu (2013)ETH-G-5494ETH-G-5494KF026071None   T12P, I15V, L19I, M36I, R41K, Q61E, L63T, H69K, T74A, L89M, I93LC
 ETH-G-5740ETH-G-5740KF026180None   I15V, E35D, M36L, R41K, K43R, Q61N, L63A, H69K, T74A, L89M, I93LC
 ETH-G-5652ETH-G-5652KF026148None   I15V, M36I, R41K, H69K, T74A, L89M, L90LW, I93LC
 ETH-G-5712ETH-G-5712KF026168None   I15V, M36I, N37D, R41K, L63V, H69K, T74A, L89M, I93LC
 ETH-G-5558ETH-G-5558KF026114None   I15V, M36IL, R41K, I62V, L63V, E65ED, H69K, K70KR, T74A, L89MC
Rusine (2013)404H404HKC841663None   T12S, I15V, L19I, M36I, R41K, L63C, H69K, T74A, L89MC
Sunpath (2013)CAS052CAS052 None   T12S, I15V, L19I, M36I, R41K, Q61E, H69K, I72V, T74A, L89M, I93LC
Telan (2013)1109703111097031AB747494None   T12S, I15V, G16E, L19I, K20R, M36I, P39S, R41K, H69K, I72R, T74A, L89M, I93LC
 1203174412031744AB747504None   L10V, I15V, M36L, R41K, L63T, H69K, T74A, L89M, I93LC
Van Zyl (2013)163346KC423997None   T12S, I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72V, T74A, L89M, I93LC
 15562418KC423701None   I15V, L19T, M36I, R41K, L63M, H69K, T74A, L89M, I93LC
 17331855KC423463None   T12S, I15V, L19I, R41K, L63P, H69K, T74A, L89M, I93LC
 10771228KC422978None   I15V, R41K, L63P, H69K, T74A, V77I, L89M, I93LC
 571388KC424031None   T12S, K14R, I15V, L19V, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 6861023KC422814None   T12S, I15V, L19I, K20R, E35D, M36I, R41K, D60E, Q61D, L63T, C67CS, H69K, T74A, V82VI, L89M, I93LC
 981005KC422799None   T12P, I13V, I15V, G16E, L19I, M36I, R41K, D60E, L63T, H69K, T74A, L89M, I93LC
 14692159KC423657None   L10I, T12S, I15V, L19I, E35G, M36I, R41K, D60E, Q61E, L63T, H69K, T74A, L89M, I93LC
 14361675KC423317None   T12S, I15V, L19I, N37S, R41K, L63LP, H69K, T74A, L89M, I93LC
 2261472KC423166None   T12P, I15V, G16E, L19I, K20R, E35D, M36I, R41K, L63T, H69K, T74A, L89M, I93LC
 17542491KC423728None   T12S, I15V, L19IT, E35D, M36I, N37D, R41K, D60E, Q61E, L63P, H69K, K70KR, I72V, T74A, L89M, I93LC
 15712205KC423682None   T12S, I15V, L19I, N37S, R41K, L63T, H69K, T74A, V77I, L89M, I93LC
 721592KC423254None   I15V, L19I, M36I, R41K, Q61E, I62V, H69K, T74A, L89M, I93LC
 3461167KC422930None   T12S, I15V, L19I, R41K, D60E, Q61N, H69K, I72V, T74A, V77I, L89M, I93LC
 2031713KC423346None   I15V, M36I, R41K, I62V, L63P, H69K, T74A, L89M, I93LC
 5412171KC423666None   I15V, L19V, M36I, L63T, H69K, T74A, V77I, L89M, I93LC
Lee (2014)MBA1043MBA1043KJ906744None   T12PQ, I15V, M36I, R41K, H69K, T74A, L89M, I93LC
Steegen (2014)11ZAKS12611ZAKS126KJ176408None   R41K, K45R, H69K, T74A, L89M, I93LC
 11ZAKS08111ZAKS081KJ176363None   R41K, L63V, H69K, T74A, L89M, I93LC
 12ZAKS21212ZAKS212KJ176492None   R41K, I62V, L63V, H69K, T74A, L89M, I93LC
 12ZAKS25412ZAKS254KJ176533None   R41K, I62V, L63P, H69K, T74A, L89M, I93LC
 12ZAKS35212ZAKS352KJ176631None   R41K, H69K, T74A, L89M, I93LC
 11ZAKS13511ZAKS135KJ176417None   R41K, I62V, L63P, H69K, T74A, L89M, I93LC
 12ZAKS27212ZAKS272KJ176551None   R41K, Q61E, H69K, T74A, V77I, L89M, I93LC