<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation G73S
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 23
Isolates 25
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Kantor (2002)TCDD-35TCDD-35_1AY090860NFV, IDV97 G73ST12S, I15V, L19I, M36I, R41K, D60E, L63AP, H69K, V75I, I93LC
Montes (2004)MB_patCOU02_COUL707AJ577870SQV, RTV, IDV, NFV221L90MG73SL10I, T12S, I15V, K20T, M36I, R41K, L63P, H69K, A71V, I93LC
Non-B Workgroup (2005)UK955UK955AY900786SQV, RTV, IDV137I54V, I84V, L90MG73S, L89VL10I, I15V, L19I, K20X, E35D, M36I, R41K, D60E, I62IV, L63P, H69K, A71V, I85V, I93LC
 TK3013TK3013 SQV, NFV205L90MG73SL10V, R41K, L63P, A71I, V77I, L89M, I93LC
 TK3019TK3019 SQV, NFV, RTV143I54V, I84IV, L90MV11VI, G73SL10I, I13V, I15V, L19I, K20R, E35D, M36I, R41K, K45R, I62V, L63P, H69T, A71V, I72L, I93LC
  TK3019a SQV, NFV, RTV149L90MG73S, T74API15V, L19I, E35D, M36I, R41K, I62V, L63P, H69T, A71V, I72L, I93LC
 TK4011TK4011 SQV, RTV, NFV, IDV261V82A, L90MQ58E, G73SL10V, T12S, I15V, L19I, K20R, M36I, L63P, H69K, A71V, I72L, I93LC
Baxter (2006)12-30823082-30430DQ877155PINAM46I, I84V, L90MG73SL10I, T12S, I13N, I15V, L19I, M36I, R41RK, Q61H, L63P, H69K, A71V, I72L, I93LC
Kassaye (2009)TCDD-28TC28_2003FJ445707SQV361L90MG73SI15V, L19I, K20I, M36I, L63P, H69K, A71V, I93LC
  TC28_2004FJ445727SQV, LPV378M46I, I84V, L90MG73SI15V, L19I, K20I, M36I, L63P, H69K, A71V, I93LC
Van Zyl (2013)16271466KC423161LPV26I54V, I84VL10F, L23I, G73S, L89VT4S, T12S, I15V, L19I, K20T, E35D, M36I, N37D, R41K, K45V, R57K, L63P, H69K, K70E, A71V, I72IM, P79PS, Q92K, I93LC
 16361248KC422997LPV26M46MI, I54V, V82A, L90ML10F, L33F, K43T, G73ST12S, I13V, I15V, L19V, K20R, E35D, M36I, R41K, Q61H, L63P, H69K, K70KR, A71V, I93LC
Grossman (2014)609609 LPV134M46I, I54V, V82A, L90MG73S, N83D, L89VL10I, V11L, I13V, K20R, A22V, E35N, M36I, N37D, R41K, K55R, I62V, L63P, H69K, A71V, T91S, I93LC
 20632063KF135018LPV52M46I, I54V, V82AL10F, G73S, L89VT12S, I15V, G16E, L19I, K20I, M36I, N37D, R41K, L63R, H69K, I85V, I93LC
Diaz (2015)RenG17235RenG17235KT748263PINAM46I, L90MG73SI15V, E35D, M36I, N37E, R41K, K55R, I62V, L63P, H69K, I93LC
 RenG16337RenG16337KT747365PINAM46I, I54V, V82A, L90ML10LF, L33F, G73ST12TS, I13V, K14R, I15V, K20R, E35D, M36I, N37K, R41N, I62V, L63P, H69K, I93LC
 RenG15755RenG15755KT746783PINAI50L, L90ML33F, G73SI13V, I15V, K20R, E35D, M36I, N37K, R41N, K45R, R57K, L63P, H69K, K70E, A71I, I93LC
 RenG17176RenG17176KT748204PINAI50L, V82A, L90MG73SI15V, G16A, K20R, E34Q, E35D, M36I, N37K, R41N, K45R, L63P, I66L, H69K, A71V, I93ILC
 RenG15346RenG15346KT746374PINAM46MI, I54V, V82VA, I84V, L90ML10F, L23LI, L33F, F53FL, G73S, T74PS, L89VV11L, I13V, I15V, K20T, E34Q, E35D, M36IL, N37K, R41N, I62V, L63P, G68D, H69R, A71V, I93LC
 RenG14545RenG14545KT745573PINAM46L, I50L, I54IV, V82VA, L90ML33LF, G73SL10V, I13IV, I15IV, K20KR, E35ED, N37K, R41N, K45R, L63P, H69K, A71AITV, T74S, V77VI, I85V, I93LC
 RenG14995RenG14995KT746023PINAI50LG73SI15V, G16A, K20KR, E35D, M36I, N37K, R41N, K45R, L63P, H69K, A71AITV, V82VI, I93LC
 RenG12354RenG12354KT743382PINAM46I, I54V, V82A, L90ML33LI, K43KT, G73SL10I, I15V, L19LP, K20KI, A22AV, E35DN, M36I, N37K, P39PQ, R41N, K45KR, I62V, L63P, C67F, H69K, A71IV, I72L, I85V, I93ILC
 RenG10574RenG10574KT741602PINAI54L, L90ML33F, G73ST12Q, I13IV, I15V, G16A, K20R, E35D, M36I, N37K, R41N, K45R, L63P, H69K, I93LC
 RenG11076RenG11076KT742104PINAI54V, V82A, L90ML23I, G73S, L89VL10I, I15V, G16GW, L19LP, K20IM, E35D, M36I, N37K, R41N, K45R, K55KR, I62V, L63P, H69K, A71T, I85V, I93LC
 RenG10661RenG10661KT741689PINAM46I, I54V, V82A, L90ML33F, Q58E, G73SL10I, I13V, L19I, K20R, E35D, M36I, N37K, R41K, K55N, L63P, H69K, A71T, T74S, Q92K, I93LC