<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation A71T
Rx PI-naive
IncludeMixtures No
References 44
Patients 79
Isolates 88
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Dowling (2002)KER2010KER2010AF457054None   I13V, L19I, K20R, M36I, R41K, I62V, L63I, H69K, A71T, L89I, I93LC
Novitsky (2002)00BW212700BW2127AF443105None   T12S, I15V, L19I, M36I, R41K, I62V, L63V, H69K, A71T, I85V, I93LC
Yang (2002)DH012DH012AB078710None   T12S, I15V, E35D, M36I, N37D, L63P, A71T, I93LC
Maljkovic (2003)MI_Pat300SE18813AY165226None   T12S, I15V, L19I, M36I, R41K, I62V, L63AV, H69K, A71T, I72M, L89X, I93LC
Deshpande (2004)in134in134AY515841None   T12S, I15V, L19T, M36V, R41K, L63T, H69K, A71T, I93LC
 in104in104AY515814None   T12P, I15V, L19I, M36V, N37S, R41K, L63P, H69K, A71T, L89M, I93LC
 in119in119AY515829None   I13V, K14R, I15V, L19V, N37S, R41K, L63P, H69K, A71T, L89M, C95CYC
Bussmann (2005)01BW2210N01BW2210NAY829309None   L10I, T12S, I15V, L19I, M36I, R41K, R57K, I62V, L63G, H69K, A71T, L89M, I93LC
 01BW3368N01BW3368NAY829315None   T12S, I15V, L19I, E35D, M36I, R41K, I62V, L63A, H69K, A71T, I93LC
Eshleman (2005)1693616936_BLAY746376None   T12S, I15V, G16E, L19I, M36L, N37E, P39S, I62V, L63P, H69K, A71T, I93LC
  16936_1YAY746377None   T12S, I15V, G16E, L19I, M36L, N37E, P39S, I62V, L63P, H69K, A71T, I93LC
  16936_2YAY746378None   T12S, I15V, G16E, L19I, M36L, N37E, P39S, I62V, L63P, H69K, A71T, I93LC
Non-B Workgroup (2005)UK740UK740AY900782None   T12S, L19I, M36I, P39Q, R41K, I62V, L63C, H69K, A71T, I72V, I93LC
 UK1988UK1988AY900830None   T12S, I15V, L19I, E35D, R41K, K45R, I62V, L63T, I64L, H69K, A71T, V77VI, I93LC
 UK2033UK2033AY900842None   T12S, I15V, L19I, M36L, R41K, I62V, L63V, H69K, A71T, I93LC
Rousseau (2006)Pt18204SK140B1AY901973None   T12S, I15V, L19I, M36I, R41K, Q61E, I62V, H69K, A71T, L89M, I93LC
Dilernia (2007)F349F349EF120244None   T12P, I15V, L19I, M36I, N37K, R41I, R57K, L63T, H69K, A71T, I93LC
 F098F098EF120337None   L10V, T12S, I15V, L19I, M36MI, N37K, R41N, R57K, L63T, H69K, A71T, I93LC
Martinson (2007)CHB398MCHB398MEU152435None   T12S, I15V, L19I, E35D, M36I, R41K, I62V, L63P, H69K, A71T, L89M, I93LC
 CHB398BCHB398BEU152436None   T12S, I15V, L19I, E35D, M36I, R41K, I62V, L63P, H69K, A71T, L89M, I93LC
Novitsky (2007)08980898_0019EF026175None   T12S, I15V, L19I, N37S, R41K, I62V, L63AS, H69K, A71T, V77I, I93L, G94EC
  0898_7976EF026176None   T12S, I15V, L19I, N37S, R41K, I62V, L63A, H69K, A71T, V77I, I93LC
  0898_6451EF026177None   T12S, I15V, N37S, R41K, I62V, L63A, H69K, A71T, I72IV, V77I, I93LC
 18981898_1854EF026227None   T12S, I15V, L19I, M36I, R41K, I62V, L63V, H69K, A71T, L89M, I93LC
  1898_4401EF026226None   L10I, T12S, I13V, I15V, L19I, M36I, R41K, I62V, L63V, H69K, A71T, L89M, I93LC
Soundararajan (2007)TRC51TRC51EF491950None   T12S, I15V, L19I, E35D, M36I, N37D, R41K, L63Q, H69K, A71T, I93LC
Church (2008)402788Z402788ZEU380753None   K14R, N37K, R41N, R57K, L63P, H69K, A71T, L89M, I93LC
Deho (2008)140140EU244655None   T12S, I15V, L19I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71T, I93LC
Ibe (2008)375375AB356365None   K14KR, L19LI, N37E, L63AD, A71T, I72TC
Kamoto (2008)MW25MW25JQ617144None   I15V, L19I, N37T, R41K, L63S, H69K, A71T, I93LC
Lahuerta (2008)P348405p348405_04EF407702None   I15V, L19T, E35D, R41K, H69K, A71T, L89M, I93LC
 P348426P348426_04EF407711None   T12S, I15V, L19I, M36V, R41K, L63P, H69K, A71T, I93LC
Matthews (2008)SK140SK140FJ199917None   T12S, I15V, L19I, M36I, R41K, Q61E, I62V, H69K, A71T, L89M, I93LC
Somi (2008)OY-05-390OY-05-390JQ616971None   I15V, L19I, E35D, R41K, L63P, H69K, A71T, I93LC
Hosseinipour (2009)94309430GQ228272None   E35D, N37E, L63P, H69K, A71T, I93LC
Kassaye (2009)TC-47TC47_2003FJ445703None   I15V, L19IT, M36I, R41K, I62V, L63S, H69K, A71T, I72E, L89M, I93LC
  TC47_2004FJ445723None   I15V, L19T, M36I, R41K, I62V, L63S, H69K, A71T, I72E, I93LC
Rajesh (2009)N58TRCNPR58FJ595421None   T12P, I15V, G16E, L19I, N37S, P39S, R41K, I62V, L63Q, H69K, A71T, I93LC
 F12TRCFPR12FJ595474None   L19I, M36MLV, N37ST, P39S, R41K, I62V, L63Q, H69K, A71T, I93LC
Wallis (2009)GT00367353GT00367353 None   T12S, I15V, L19I, E35D, M36I, P39Q, R41K, R57K, L63A, H69K, A71T, I93LC
 ReA2GT02 None   T12S, I15V, L19T, E35D, M36I, R41K, L63P, H69K, A71T, I72V, I93LC
 TJC2413549TJC2413549 None   T12S, I15V, L19I, M36I, N37D, R41K, I62IV, L63C, H69K, A71T, I93LC
 GT00366729GT00366729 None   T12S, I15V, L19I, K20R, M36I, N37E, P39Q, R41K, K43KR, I62V, H69K, A71T, I93LC
Gonzalez (2010)914_M00m914_M00mGQ427114None   L10V, I15V, Q18H, L19I, M36I, N37S, R41K, L63S, H69K, A71T, P79S, I93LC
 MA4MA4GQ433865None   T12S, I15V, L19I, M36I, R41K, L63Q, H69K, A71T, I93LC
Papathanasopoulos (2010)1692306ZA16923GU253416None   T12S, I15V, G16E, L19T, K20M, E35D, M36I, I62V, L63A, H69K, A71T, I93LC
Rodrigues (2010)322_07BR07SC322GQ401306None   I15V, L19T, M36I, N37K, R41I, L63P, H69K, K70R, A71T, I93LC
Wright (2010)140SK140HM593148None   L10LV, T12S, I15V, L19I, M36I, R41K, Q61E, I62IV, L63LP, H69K, A71T, L89M, I93LC
Bussmann (2011)B0690B0690JQ616996None   I15V, L19I, M36I, R41K, I62V, L63A, H69K, A71T, L89M, I93LC
 B0781B0781JQ617043None   I15V, L19T, M36I, R41K, I62V, L63A, H69K, A71T, I93LC
 B0564B0564JQ617058None   I15V, L19IV, M36MI, N37NS, R41K, I62V, L63V, I64L, H69K, A71T, L89M, I93LC
 B0566B0566JQ617060None   L19V, E34G, M36I, R41K, L63P, H69K, A71T, L89M, I93LC
 B0672B0672JQ617127None   I15V, L19I, E35D, M36I, N37E, R41K, R57K, D60E, L63T, H69K, A71T, I72T, I93LC
Deshpande (2011)Pat023in1100JF414447None   T12S, L19I, M36I, R41K, L63P, H69Q, A71T, I72IM, I93LC
Hamers (2011)300071CP076300071HM119658None   T12S, I13X, I15V, L19I, E35D, M36MI, N37S, R41H, I62IV, L63LHQ, H69K, A71T, I93LC
 300136CP076300136HM119712None   T12S, I15V, G16E, L19I, R41K, L63H, H69K, A71T, L89I, I93LC
 300504CP076300504HM119921None   T12S, I15V, L19I, M36I, N37D, R57K, L63S, H69K, A71T, I93LC
 300577CP076300577HM119981None   L10V, T12S, I15V, L19I, M36I, R41K, L63P, H69K, A71T, I72T, I93LC
 302381CP076302381HM120095None   T12S, I15V, L19I, M36I, R41K, R57RK, I62V, L63V, H69K, A71T, I72IEKV, I93LC
 CP076304264CP076304264HQ993952None   T12S, I15V, L19I, M36I, P39PS, R41K, I62V, L63V, H69K, A71T, I93LC
 CP076303179CP076303179HQ994195None   T12S, I15IV, L19T, M36I, R41K, R57K, L63T, H69K, A71T, I93LC
 CP076303222CP076303222HQ994228None   T12S, I15V, L19I, M36I, R41K, L63P, H69K, A71T, I72T, L89I, I93LC
 CP076305120CP076305120HQ994341None   T12S, I15V, L19I, E35D, M36I, R41K, R57RK, I62V, L63ST, H69K, A71T, I93LC
 CP763A03301CP763A03301HQ994622None   T12S, I15V, L19T, E35D, M36I, R41K, K45R, I62V, L63V, H69K, A71T, I72V, I93LC
Nwobegahay (2011)BBVCT57ZABBVCT57ZAGU139631None   L19I, E35D, M36I, R41K, R57K, L63I, H69K, A71T, I72V, I93LC
Sigaloff (2011)GT00366729GT00366729_1JN381607None   T12S, I15V, L19I, K20R, M36I, N37E, P39Q, R41K, K43KR, I62V, H69K, A71T, I93LC
  GT00366729_2JN381608None   T12S, I15V, L19I, K20R, M36I, N37E, P39Q, R41K, K43R, I62V, H69K, A71T, I93LC
De Gascun (2012)IRL26089IRL26089JN622914None   R8RG, T12S, K14KI, I15V, L19I, M36I, R41K, K55KT, I62IV, L63LIPT, H69K, A71T, I72V, I93LC
Hunt (2012)GP06_193039GP06_193039KF736553None   L10I, E35D, P39Q, R41K, Q61N, L63AV, H69K, A71T, I93LC
 GP08_0391GP08_0391KF736649None   T12P, I15V, L19I, E35D, M36I, R41K, I62V, L63H, H69K, A71T, L89LM, I93LC
Iweriebor (2012)07B1ZA07B1ZAGU201798None   I15V, G17D, L19V, M36I, N37T, L63P, H69K, A71T, L89I, I93LC
Sigaloff (2012)KELKN220KELKN220JN628493None   T12S, I15V, L19I, M36I, R41K, I62V, L63S, H69K, A71T, I93LC
Bila (2013)MZ10-138HIV-1KF927247None   I15V, L19I, E35D, M36I, R41K, R57K, L63C, H69K, A71T, I93LC
Ferreira (2013)BR09SP242BR09SP242HM534027None   T12P, K14R, I15V, M36I, N37K, R41N, L63V, H69K, A71T, I93LC
Han (2013)LC216005ILC216005IJX070521None  L89VT12S, K14R, I15V, L19I, M36I, R41K, L63P, H69K, A71T, I93LC
Kiertiburanakul (2013)R71133R71133KC921843None   L19I, M36I, N37D, R41K, L63P, H69K, A71T, I72E, I93LC
Van Zyl (2013)13822035KC423578None   T12S, I15V, L19T, R41K, L63S, H69K, A71T, V77I, I93LC
 13091667KC423312None   T12S, I15V, L19I, E35D, M36I, N37D, R57K, Q61D, L63Q, H69K, A71T, I93LC
 400956KC424393None   T12P, K14E, L19K, K20R, E35D, M36I, R41K, K45R, L63T, H69K, A71T, I72T, L89M, I93LC
 6741060KC422846None   T12S, L19T, E35D, M36I, R41K, R57RK, L63S, H69K, A71T, I93LC
 8162050KC423587None   I15V, L19V, E35D, R41K, L63IV, H69K, A71T, I93LC
 17612742KC423808None   T12S, L19I, M36I, N37E, R57K, L63P, H69K, A71T, I93LC
 13361160KC422925None   T12S, I15V, L19V, E35D, R57RK, Q61E, L63P, H69K, A71T, V77I, L89M, I93LC
Bartolo (2014)09AOHDP20009AOHDP200KF853793None   T12S, I15V, L19I, K20R, M36I, P39Q, R41K, K45R, L63P, H69K, A71T, I93LC
Steegen (2014)11ZAKS09411ZAKS094KJ176376None   R41K, L63P, H69K, A71T, I93LC
 11ZAKS15211ZAKS152KJ176434None   R41K, R57K, D60E, I62V, L63T, H69K, A71T, L89I, I93LC
 11ZAKS18511ZAKS185KJ176466None   R41K, K43R, I62V, L63S, H69K, A71T, I93LC
 11ZAKS13411ZAKS134KJ176416None   R41K, R57K, Q61H, H69K, A71T, I72E, I93LC