<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation A71T
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 22
Isolates 25
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK1147UK1147AY900794IDV, NFV117M46IK43TT12S, I15V, L19I, K20T, E35D, M36I, N37D, D60E, Q61E, L63P, H69K, A71T, L89T, I93LC
 PL472558294 Unknown, LPV>4G48V, I54V, V82T, L90MQ58EL10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93LC
  69936 Unknown, LPV>51G48V, I54V, V82S, L90MQ58EL10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95CFC
  80404 Unknown, LPV>90G48V, I54V, V82S, L90MQ58EL10V, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55R, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95FC
  100703 Unknown, LPV, APV>159M46ML, G48V, I54V, V82S, L90MV11VI, L33F, Q58EL10V, I13V, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55R, I62V, L63P, H69K, K70KR, A71T, I72IM, T74S, I85V, L89I, I93L, C95F, T96SC
Baxter (2006)48-22542254-30930DQ877888PINAG48V, I54V, V82S, L90ML33F, Q58EL10V, I13IV, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57RK, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95F, T96TSC
Van Zyl (2013)15541662KC423308LPV26  I15V, L19I, E35D, M36L, N37E, R41K, I64V, H69K, A71T, I93LC
 13922151KC423653LPV26  T12S, I15V, L19I, K20R, E35D, M36I, N37ND, R41K, R57K, I62V, H69K, A71T, L89M, I93LC
 758374KC424019LPV26  T12S, I15V, L19V, E35D, M36L, R41K, L63T, H69K, A71T, I93LC
 16501081KC422867LPV26  T12S, I15V, L19T, K20R, E35D, M36I, R41K, D60E, Q61E, I62V, L63LP, H69K, A71T, L89M, I93LC
Grossman (2014)183183KF135005NFV, LPV52M46I, I54V, V82F, L90M L10I, I13V, I15V, L19T, K20T, E35N, M36I, R41K, K45R, H69K, A71T, T74S, V77I, L89I, I93L, C95YC
Steegen (2014)10ZAKS06910ZAKS069KJ176351LPV   R41K, I62V, L63H, H69K, A71T, I93LC
Diaz (2015)RenG17081RenG17081KT748109PINA  N37K, R41N, Q61E, I62V, H69K, A71T, I72V, I93LC
 RenG16715RenG16715KT747743PINAD30N, I54LN88DL10Y, I15V, L19Q, K20T, E35D, M36I, N37K, R41N, L63V, H69K, A71T, L89T, I93LC
 RenG14790RenG14790KT745818PINA  I15V, E35D, N37DE, R41N, K43R, D60N, I62IV, L63P, H69K, A71T, I72V, L89LI, I93LC
 RenG15065RenG15065KT746093PINAM46I, I50L, L90MQ58EI13V, I15V, L19I, K20R, E35D, M36I, N37K, R41N, K55R, L63P, H69K, A71T, L89I, I93LC
 RenG11998RenG11998KT743026PINAI50L I15V, G16A, K20R, E35D, M36I, N37K, R41N, K45R, L63P, H69K, A71T, V82VI, L89T, I93LC
 RenG13278RenG13278KT744306PINAI54IL, I84V, N88SL33F, Q58EL10Y, I13V, I15V, K20R, E35D, M36I, N37K, R41N, K45R, R57K, D60E, Q61E, I62V, L63P, H69K, A71T, L89M, I93LC
 RenG12519RenG12519KT743547PINAM46I, I54V, V82A, L90ML10F, L23II13V, K14R, I15V, K20I, E35N, M36I, N37E, R41N, Q61H, I62V, L63P, H69K, A71T, T74S, L89I, I93LC
 RenG10624RenG10624KT741652PINAL90MQ58EI13V, K14R, I15V, K20T, E35G, M36I, N37K, P39S, R41N, Q61N, L63T, I64IV, H69K, A71T, T74A, V82I, L89I, I93LC
 RenG10952RenG10952KT741980PINA L23II13V, I15V, K20R, E35D, M36I, N37K, R41N, K45R, Q61H, L63P, H69K, A71T, L89T, I93LC
 RenG11076RenG11076KT742104PINAI54V, V82A, L90ML23I, G73S, L89VL10I, I15V, G16GW, L19LP, K20IM, E35D, M36I, N37K, R41N, K45R, K55KR, I62V, L63P, H69K, A71T, I85V, I93LC
 RenG10661RenG10661KT741689PINAM46I, I54V, V82A, L90ML33F, Q58E, G73SL10I, I13V, L19I, K20R, E35D, M36I, N37K, R41K, K55N, L63P, H69K, A71T, T74S, Q92K, I93LC
Novitsky (2015)bcpp_087bcpp_087KR860637PINA  T12P, I15V, L19I, E35D, M36I, N37D, R41K, I62V, L63T, E65D, H69K, A71T, I93LC
Rossouw (2015)RP142RP142KT032051RTV, LPV95V82A T12S, L19I, K20R, A28AS, M36I, R41K, L63P, H69K, K70KQ, A71T, I93LC