<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation A71I
Rx >= 1 PI
IncludeMixtures No
References 3
Patients 10
Isolates 11
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)TK3013TK3013 SQV, NFV205L90MG73SL10V, R41K, L63P, A71I, V77I, L89M, I93LC
 TK3024TK3024 SQV, NFV205L90M T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, L63P, H69K, A71I, T74S, I93LC
  TK3024a SQV, NFV, LPV246L90M T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45KR, L63P, H69K, A71I, T74S, I93LC
 TK3026TK3026 RTV, SQV, NFV292L90M I15V, L19I, K20T, E35D, M36I, R41RK, L63P, H69K, A71I, T74S, L89I, I93LC
Weber (2005)F30356F30356AY677479Unknown, NFV>201I54V, V82A, L90M L10I, T12S, I15V, L19T, K20R, E35D, M36I, N37H, P39PS, R41K, K45R, L63P, H69KQ, A71I, I93LC
Diaz (2015)RenG17053RenG17053KT748081PINAI50L, L90ML33IL10Y, I13IV, I15V, K20T, E34EQ, E35N, M36I, N37E, R41N, K45R, D60N, I62IV, L63LP, C67CF, G68GE, H69KR, A71I, L89I, I93LC
 RenG15755RenG15755KT746783PINAI50L, L90ML33F, G73SI13V, I15V, K20R, E35D, M36I, N37K, R41N, K45R, R57K, L63P, H69K, K70E, A71I, I93LC
 RenG13855RenG13855KT744883PINAL90ML23I, F53LI13V, I15V, K20T, E35D, M36I, N37K, R41N, I62V, L63P, H69K, A71I, T74A, L89I, I93LC
 RenG13882RenG13882KT744910PINAL90M L10I, V11F, I15V, L19I, K20I, L33V, R41K, K45R, L63P, H69K, A71I, L89T, I93LC
 RenG11780RenG11780KT742808PINAI54IV L10Y, I15V, K20I, E35G, M36I, N37K, R41N, K45R, H69K, A71I, T74S, I85V, L89T, I93LC
 RenG11404RenG11404KT742432PINAM46I, I54V, V82AV11I, L24I, L33FL10V, I13V, I15V, K20R, E35D, M36I, N37NK, R41P, K45KR, I62V, L63Q, G68DE, H69K, A71I, L89T, I93LC