<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63T
Rx >= 1 PI
IncludeMixtures No
References 30
Patients 176
Isolates 189
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Kantor (2002)TCDD-08TCDD-08_1AY090845SQV95  I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72IT, T74S, L89M, I93LC
Soares (2003)BR54BR54AY275730NFV56  T12A, I13V, G16E, L19I, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
Gomez-Carrillo (2004)9610596105AY365516PINA  T12A, I15S, G16R, E35D, M36I, N37K, R41N, L63T, H69K, I72T, T74S, L89M, I93LC
Grossman (2004)IL49IL49AY529530NFV64N88NS, L90LM Q7QK, L10LI, I15V, G16E, K20RT, E35D, M36I, L38LM, R41RK, R57K, L63T, H69K, T74TS, L89M, I93LC
 IL160IL160AY529612SQV, NFV128D30NN88DT12S, I15V, L19I, K20I, M36I, P39PS, R41K, K45R, L63T, H69K, A71IV, I93LC
 IL287IL287AY529620SQV, RTV, IDV, NFV184I84V, L90M L5LI, L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63T, H69K, A71V, T74S, I93LC
 IL433IL433aAY529600IDV117M46ML, V82A, L90LMQ58EL10C, I15V, K20R, M36I, K45KR, L63T, H69K, L89M, I93LC
 IL708IL708AY529608NFV44I84C I15V, K20R, M36I, R41K, L63T, H69K, I72T, I93LC
Non-B Workgroup (2005)UK973UK973AY900789NFV54  T12S, I15V, L19T, K20KT, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
 IL273IL273 NFV, IDV, RTV137  I15V, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 TK3020TK3020a RTV, NFV, SQV120  T12S, I15V, L19I, E35D, M36I, R41K, L63T, H69K, T74S, L89I, I93LC
 TK3022TK3022 SQV, NFV103  T12S, I15V, L19I, K20R, E35D, M36I, K43R, L63T, H69K, L89M, L97LIC
Rhee (2005)CA7907CA24813AY797580IDV, NFV260D30NL10F, N88DT12P, K14R, I15V, G16E, K20IT, E35G, M36V, R41K, L63T, H69Q, T74S, V77VI, I85IV, L89M, I93LC
Weber (2005)F36402F36402AY714443IDV, SQV, Unknown>65M46I, I84V, L90ML10F, T74PI15V, L19I, K20IMT, M36I, R41K, K43R, Q61H, I62V, L63T, I64V, H69K, L89M, I93LC
Baxter (2006)12-17161716-30421DQ876854PINAM46L, I54V, V82A, I84VL24I, L33F, K43TL10I, I15V, K20R, E35D, M36I, N37ND, R41K, I62V, L63T, H69K, T74S, L89M, I93LC
 12-31023102-30610DQ877250PINAL90ML23I, L33F, F53L, Q58EL10I, T12P, I15V, G16E, L19V, K20R, E35D, M36I, N37T, I62V, L63T, H69K, T74A, V82I, I85V, L89M, I93LC
Doualla-Bell (2006)Pt5FDB_Pt5 NFV N88SL10FI15V, L19I, K20T, E35D, M36I, R41K, Q61H, L63T, H69K, T74S, L89M, I93LC
 Pt7FDB_Pt7 NFV D30NL33FL10M, V11F, I13V, I15V, K20R, E35D, M36I, R41K, I62V, L63T, H69K, I93LC
Sen (2007)T009NPT9EF186927SQV, RTV   T12S, K14R, I15V, G16E, L19I, M36IV, R41K, Q61H, L63T, H69K, L89M, I93LC
  NPT9-PLEF186959SQV, RTV   T12S, K14R, I15V, G16E, L19I, M36V, R41K, Q61H, L63T, H69K, L89M, I93LC
von Wyl (2007)19702313EF449901PINAI54IV, N88NS, L90M L10V, T12K, I15V, G16E, L19I, K20R, E35D, M36IV, N37Q, P39Q, R41N, D60DN, Q61QH, I62V, L63T, H69K, A71AV, I72IT, T74A, L89M, I93LC
 374822080EF449879PINA  M36I, R41K, L63T, H69KN, T74S, L89M, I93LC
Marconi (2008)SW068SW068EU308079LPV23  I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
Pillay (2008)DR54DR54AY589907NFV, RTV   L19T, M36L, R41K, L63T, H69K, T74S, L89M, I93L, F99FLC
 DR9303ZA.DR93AY589932IDV, LPV M46I, L90M L10R, T12S, G17D, L19T, K20M, M36I, R41K, K55KR, L63T, H69K, I72T, L89M, I93LC
Riddler (2008)RG9485RG9485w19 LPV26  T12S, I15V, L19I, M36I, L63T, H69K, I93LC
Kandathil (2009)VL06_192VL06_192EU037774PINA  T12S, I15V, L19I, E35D, M36I, N37E, L63T, H69K, T74S, L76X, L89M, I93LC
 VL07_109VL07_109EU781834PINA  T12S, I15V, G16E, L19I, M36I, R41K, L63T, H69K, I93LC
 VL07_108VL07_108EU781837PINA  T12S, K14R, I15V, G16E, L19I, M36V, R41K, D60E, Q61E, L63T, H69K, I93LC
Kassaye (2009)TCDD-08TC08_2003FJ445719SQV210  I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72T, T74S, L89M, I93LC
  TC08_2004FJ445726SQV239  I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72T, T74S, L89M, I93LC
Dau (2010)07762A07762AGU581866PINA  K14KR, I15V, K20KR, M36I, N37K, R41N, L63T, H69K, T74S, L89M, I93LC
El-Khatib (2010)Pat07911ZA_SAVE1255JF960529LPV   T12S, I15V, L19V, E35D, M36I, R41K, K45R, L63T, H69K, T74S, V82VI, L89M, I93LC
Rodrigues (2010)301_07BR07SC301GQ401314SQV, RTV, LPV M46L, G48V, I54V, V82SL24I, L33F, T74PL10V, I13V, I15V, G16E, K20M, E34Q, E35D, M36I, N37NKT, R41N, K55R, L63T, H69K, L89M, I93LC
 331_07BR07SC331GQ401326NFV   I15V, L19Q, M36I, N37K, R41N, D60E, L63T, H69K, L89M, I93LC
Barber (2012)6957669576JQ361677LPV I54V, V82AL10FT12S, I15V, L19I, M36I, R41K, L63T, H69K, L89M, I93LC
Van Zyl (2013)33711.ZA.WC155KC423504LPV   L10I, T12S, I15V, L19I, M36I, R41K, L63T, H69Q, I72T, I93LC
 303807.ZA.GT081KC424144LPV   L10I, T12S, I15V, L19T, K20R, M36I, R41RK, D60DE, Q61E, I62IV, L63T, E65D, H69K, L89M, I93LC
 704311.ZA.EC098KC423703LPV   T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, K45R, D60E, Q61E, I62V, L63T, H69K, L89M, I93LC
 349908.ZA.GT498KC423694LPV   L10I, I15V, L19I, M36I, P39PQ, R41K, L63T, H69Q, L89M, I93LC
 405211.ZA.GT1874KC423649LPV   I15V, L19T, K20R, M36I, R41K, L63T, H69K, V75I, L89M, I93LC
 360409.ZA.GT633KC424200LPV   T12S, I15V, L19I, M36L, N37S, R41K, L63T, C67F, H69K, L89M, I93LC
 364111.ZA.GT1597KC423388LPV   L10V, G16E, M36I, N37Q, R41K, D60E, L63T, H69K, I72V, I93LC
 288508.ZA.GT573KC423983LPV   T12S, I15V, L19I, K20R, M36I, R41K, L63T, H69K, L89M, I93LC
 313208.ZA.GT366KC424143LPV   L10I, K14S, I15V, L19I, M36I, R41K, L63T, I64M, H69K, I72V, L89M, I93LC
 297108.ZA.GT605KC424004LPV   K14R, I15V, G17D, L19I, K20R, M36I, P39S, R41K, L63T, E65D, H69K, I72T, L89M, I93LC
 330007.ZA.GT105KC422971LPV   I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
 42712.ZA.MP001KC423906LPV   L10V, T12TS, K14KR, I15V, G16E, L19I, M36I, K45R, L63T, H69K, L89M, I93LC
 378111.ZA.GT1905KC423695LPV   T12S, K14R, I15V, L19I, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 385510.ZA.GT1227KC423063LPV   T12S, I15V, L19T, K20R, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, H69K, I93LC
 54007.ZA.WC004KC424028LPV   K14N, I15V, L19R, M36I, N37D, R41K, D60DE, Q61QE, L63T, H69K, L89M, I93LC
 29411.ZA.WC148KC423474LPV   I15V, L19LV, K20R, M36I, N37Q, R41N, D60N, I62V, L63T, H69K, L89M, I93LC
 327211.ZA.GT1915KC423704LPV M46I, I54V, L76V, V82AL10FT12P, I15V, G16E, L19P, K20M, M36I, L63T, I64IV, H69K, L89M, I93LC
 81710.ZA.GT1294KC423126LPV   T12S, L19I, K20R, M36I, R41K, L63T, H69K, K70KR, L89M, I93LC
 62512.ZA.WC208KC423813LPV M46I, I54V, L76V, V82AL10FI13V, G16E, L19I, K20R, M36I, N37Q, R41K, D60E, L63T, H69K, L89M, I93LC
 348611.ZA.GT1485KC423273LPV   T12S, K14R, I15V, G16E, L19V, M36I, N37K, R41K, K43R, R57K, L63T, H69K, V82I, L89M, I93LC
 296507.ZA.GT186KC424019LPV   T12S, I15V, L19V, E35D, M36L, R41K, L63T, H69K, A71T, I93LC
 305208.ZA.GT468KC423603LPV   K14KR, I15IV, L19IT, M36I, N37D, L63T, H69K, T74S, L89M, I93LC
 96611.ZA.WC171KC423550LPV   T12S, I15V, L19I, K20R, E35D, M36I, N37E, R41K, D60E, Q61E, I62V, L63T, G68E, H69K, L89M, I93LC
 208511.ZA.GT1887KC423660LPV   T12S, I15V, G17D, L19T, K20R, M36I, R41K, L63T, H69K, I93LC
 14212.ZA.NL013KC423795LPV   L10I, K14T, I15V, L19V, M36I, R41K, L63T, E65D, H69K, L89M, I93LC
 75410.ZA.WC099KC423201LPV  V11VIT12S, L19T, K20R, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 343810.ZA.GT1370KC423181LPV L90M G17D, L19I, M36I, L63T, H69K, L89M, I93LC
 255808.ZA.GT626KC424197LPV   T12S, L19I, M36I, R41K, L63T, H69K, I93LC
 327109.ZA.GT819KC424321LPV M46I, I54V, V82AL10FT12P, I15V, G16E, L19P, K20T, M36I, L63T, H69K, I93LC
 105610.ZA.GT1333KC423150LPV M46I, I54V, V82A T12S, I15V, G16E, L19I, K20M, E35D, M36I, L63T, H69K, T74S, L89M, I93LC
 332609.ZA.GT717KC424255LPV   T12S, I15V, L19I, M36I, N37S, R41K, L63T, H69K, L89M, I93LC
  11.ZA.GT1508KC423292LPV   T12S, I15V, L19I, M36I, N37S, R41K, L63T, H69K, L89M, I93LC
 273111.ZA.GT1852KC423634LPV  V11IL10I, I13V, G16E, Q18K, L19T, K20R, M36I, R41K, K43I, R57RK, L63T, H69K, L89M, I93LC
 701911.ZA.GT1594KC423385LPV   K14N, I15V, G16E, L19T, K20R, M36I, L63T, H69K, L89I, I93LC
 192812.ZA.GT2293KC423933LPV I54IV, V82VAG48GET12S, I15IV, L19V, K20R, E35D, M36I, N37D, Q61E, I62IV, L63T, E65D, H69K, A71AV, I72V, T74S, L89M, I93LC
 265811.ZA.GT1630KC423425LPV   T12P, I15V, L19I, K20R, E35D, M36I, N37D, R57RK, L63T, G68E, H69K, L89M, I93LC
 286111.ZA.GT1606KC423398LPV   T12S, L19T, K20R, M36I, R41K, L63T, H69K, L89M, I93LC
 304109.ZA.GT893KC424387LPV   T12S, I15V, G16E, L19I, M36I, N37NS, R41K, L63T, H69K, I72IT, L89M, I93LC
  12.ZA.GT2198KC423873LPV   T12S, I15V, G16E, L19I, M36I, N37NS, R41K, L63T, H69K, I72IT, L89M, I93LC
  12.ZA.GT2277KC423928LPV   T12S, I15V, G16E, L19I, M36I, R41K, L63T, H69K, L89M, I93LC
 346008.ZA.GT623KC424196LPV   I15V, L19T, K20R, M36I, R41K, L63T, H69K, V75I, L89M, I93LC
  10.ZA.GT1207KC423039LPV   I15V, L19T, K20R, M36I, R41K, L63T, H69K, V75I, L89M, I93LC
 83509.ZA.GT716KC424257LPV   I15V, L19V, R41K, L63T, H69K, T74S, V77I, L89M, I93LC
  10.ZA.GT1198KC423037LPV   I15V, L19V, R41K, L63T, H69K, T74S, V77I, L89M, I93LC
  11.ZA.GT1750KC423539LPV   I15V, L19V, R41K, L63T, H69K, T74S, V77I, L89M, I93LC
 323712.ZA.GT2309KC423945LPV   I13IV, L19T, K20R, M36I, R41K, L63T, H69K, I93LC
 204607.ZA.GT228KC424054LPV   I15V, G16E, L19I, E35D, M36I, R41K, K45R, L63T, H69K, V82VI, L89M, I93LC
  07.ZA.GT333KC424130LPV   I15V, G16E, L19I, E35DN, M36I, P39PT, R41K, K45R, L63T, H69K, L89M, I93LC
 322309.ZA.GT1019KC422873LPV   T12S, I15V, L19I, M36I, R41K, K45R, L63T, H69K, L89M, I93LC
Grossman (2014)16281628KF134991LPV52 V11IR8T, P9T, L10I, I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
 4949KF135089NFV, LPV52I54V, V82A, L90ML10F, L33F, T74PI13V, I15V, G16E, K20MT, E35N, M36I, R41K, R57K, Q61QHKN, I62IV, L63T, H69K, A71V, I93LC
 101101KF134929IDV, LPV52  W6MR, T12S, K14Y, I15V, L19T, K20R, M36I, R41K, L63T, H69K, I93LC
  101KF134930IDV, LPV156M46L, V82AL10F, L33F, K43T, F53FL, T74PT12S, G16E, L19T, K20R, E35D, M36I, N37NY, R41K, K55R, L63T, E65ED, H69K, L89M, I93LC
 762762KF135137LPV52  T12S, I15V, L19V, M36I, R41K, L63T, H69K, L89M, I93LC
 11201120KF134953LPV52  I15V, M36I, R41K, L63T, H69K, L89LM, I93LC
 976976KF135172LPV52  K14R, I15V, L19I, M36I, N37D, R41K, L63T, H69K, L89M, I93LC
 311311KF135047LPV52 T74TPT12S, I15V, L19IT, K20KI, E35ED, M36I, Q61E, L63T, H69K, L89IM, I93LC
  311KF135048LPV148M46L, I47A T12S, I13IV, I15V, L19K, K20I, M36I, Q61E, L63T, H69K, T74S, L89I, I93LC
 805805KF135148SQV, LPV52M46I, I54IV, L76V, V82VAL10LFT12TS, I15V, G16E, L19I, K20T, E35D, M36I, R41K, L63T, H69K, I85IV, L89I, I93LC
 188188KF135010IDV, LPV52  K14T, I15V, K20R, M36I, R41RK, L63T, H69K, L89M, I93LC
 1313KF134975IDV, LPV52  T12A, M36I, R41K, L63T, H69K, L89M, I93LC
 160160KF134989SQV, LPV52D30NN88DT12V, L19I, K20I, M36I, R41K, K45R, L63T, H69K, A71V, I93LC
 260260KF135035IDV, LPV384I54V, V82A, L90ML10FI15V, G16E, K20M, M36I, R41K, I62V, L63T, H69K, A71V, T74TS, L89I, I93LC
 504504 IDV, LPV52  T12TA, I13V, K14KR, I15V, M36I, R41K, L63T, I64M, H69K, L89M, I93LC
 610610 NFV, IDV, LPV52M46I, I54V, V82A, L90ML10F, T74PST12S, I13V, I15V, L19Q, K20I, E35D, M36I, N37ND, R41K, Q61H, I62V, L63T, I64V, I66L, H69K, L89M, I93LC
  610 NFV, IDV, LPV69M46I, I54V, L76V, V82A, L90ML10FT12S, I13V, I15V, L19Q, K20I, E35D, M36I, R41K, Q61N, I62V, L63T, I64V, I66L, H69K, T74S, L89M, I93L, C95FC
Steegen (2014)12ZAKS33312ZAKS333KJ176612LPV   R41K, L63T, H69K, L89M, I93LC
 11ZAKS11111ZAKS111KJ176393LPV   R41K, L63T, I64IL, H69K, V82I, L89M, I93LC
 12ZAKS27112ZAKS271KJ176550LPV V82A R41K, K45R, L63T, H69K, T74S, L89M, I93LC
 11ZAKS17111ZAKS171KJ176452LPV M46I, I50V, I54V, V82A R41K, K55R, R57K, Q61H, L63T, H69K, A71V, I72K, T74S, L89M, I93LC
 12ZAKS28212ZAKS282KJ176561LPV I47A, V82C R41K, L63T, H69K, I93LC
Diaz (2015)RenG16936RenG16936KT747964PINA  L10I, G16E, N37K, R41IT, R57K, D60E, L63T, H69K, L89M, I93LC
 RenG17384RenG17384KT748412PINA  I15V, L19LI, K20R, M36I, N37K, R41N, R57RK, L63T, H69K, L89M, I93LC
 RenG17353RenG17353KT748381PINAM46I, I54V, L76V, V82AL10F, L33FI13V, K14KR, K20R, E35D, M36I, R41N, I62V, L63T, H69K, A71V, I72V, T74TA, L89M, I93LC
 RenG15849RenG15849KT746877PINA  I15V, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG17470RenG17470KT748498PINA  L10V, T12I, I15V, G16E, E35D, M36I, N37K, R41N, L63T, H69K, I72V, L89M, I93LC
 RenG16317RenG16317KT747345PINAM46I, I54V, V82AL10F, Q58E, T74P, N88GI15V, G16E, K20T, E21K, E35G, M36I, N37K, P39S, R41N, L63T, H69K, V77I, L89MC
 RenG16825RenG16825KT747853PINA  L10I, M36I, N37K, R41N, L63T, H69K, L89M, I93L, N98IC
 RenG16641RenG16641KT747669PINAM46I, I84V L10V, I15V, G16E, E35G, M36I, N37K, P39S, R41N, I62V, L63T, I64V, H69K, T74A, I85V, L89M, I93LC
 RenG16982RenG16982KT748010PINAM46L, I54IV, V82AL10LFPS, L23I, L33F, F53FLP9PR, T12I, I13V, I15V, G16E, M36L, N37K, R41R_N, G51A, D60E, I62LV, L63T, H69K, A71V, L89I, T91TA, I93LC
 RenG14027RenG14027KT745055PINAI54V, V82AK43KTI15V, G16E, K20R, E35D, M36IV, N37KT, P39PS, R41KN, D60E, Q61N, L63T, H69K, T74TA, V77VI, L89M, I93LC
 RenG14203RenG14203KT745231PINA  I15V, L19IV, M36I, N37K, R41N, L63T, H69K, V82I, I93LC
 RenG13952RenG13952KT744980PINA  I15V, M36I, N37K, R41N, K45R, L63T, H69K, L89M, I93LC
 RenG14874RenG14874KT745902PINAM46I, N88S I15V, K20T, E35D, M36I, N37K, R41N, L63T, I64IV, H69K, T74S, L89M, I93LC
 RenG15067RenG15067KT746095PINA  T12A, I13V, K14R, I15V, G16E, M36I, N37K, R41N, K45R, D60E, Q61N, L63T, H69K, L89I, I93LC
 RenG14451RenG14451KT745479PINA  L10I, L19I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG14721RenG14721KT745749PINA  W6G, L10I, M36I, N37E, R41N, D60N, L63T, H69K, L89M, I93LC
 RenG14536RenG14536KT745564PINAD30N, I54ILM, I84IVL10F, L33F, N88DI15V, G16E, K20T, E35D, M36I, N37EK, P39S, R41N, K45I, L63T, H69K, T74AS, I85V, L89M, I93ILC
 RenG14962RenG14962KT745990PINAM46I, I54V, V82AL10F, L24I, L33FI15V, G16E, L19Q, K20R, E35D, M36I, N37K, R41N, Q61H, L63T, H69K, L89I, Q92K, I93LC
 RenG13551RenG13551KT744579PINAM46MI, I50V, I54V, V82M, N88SL33F, Q58E, T74PL10V, G16E, K20R, E35D, M36I, N37K, R41N, R57RK, L63T, H69K, L89F, I93LC
 RenG15224RenG15224KT746252PINA  M36I, N37K, R41N, L63T, H69K, I72T, T74S, L89M, I93LC
 RenG14258RenG14258KT745286PINA  L10V, I15V, G16A, M36I, N37K, R41N, I62V, L63T, H69K, T74A, L89M, I93LC
 RenG15313RenG15313KT746341PINAM46L, G48A, I54V, V82A, L90ML33F, N83DL10V, K14KR, I15IV, G16E, K20R, E35D, M36I, N37K, R41N, R57K, Q61N, L63T, H69K, T74S, I85V, L89I, Q92K, I93LC
 RenG14857RenG14857KT745885PINA  I15V, G16E, M36T, N37K, R41N, L63T, H69K, L89I, I93LC
 RenG14092RenG14092KT745120PINA  T12P, K14KR, I15V, G16E, N37R, R41N, D60E, Q61D, L63T, H69K, I72K, L89M, I93LC
 RenG14739RenG14739KT745767PINA  M36I, R41H, D60E, L63T, H69K, L89M, I93LC
 RenG15422RenG15422KT746450PINA  L10M, I15IV, L19LI, N37K, R41N, L63T, H69K, I93LC
 RenG15333RenG15333KT746361PINA  L10V, G16E, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG12208RenG12208KT743236PINA  I13V, M36I, N37K, R41N, D60E, Q61DN, L63T, H69K, L89M, I93LC
 RenG13483RenG13483KT744511PINA  T12N, I15V, N37K, R41N, D60E, L63T, H69K, L89MC
 RenG13267RenG13267KT744295PINA  T12A, K14R, I15V, G16E, M36I, N37K, R41N, Q61KN, L63T, H69K, L89I, I93LC
 RenG13457RenG13457KT744485PINA  L10V, I13IV, K14KNRS, L19I, K20KR, M36I, N37K, R41N, L63T, H69K, L89MC
 RenG13229RenG13229KT744257PINA  T12TA, I15S, G16R, M36I, N37K, R41N, Q61QH, L63T, H69K, I72IT, L89M, I93LC
 RenG13433RenG13433KT744461PINAI50L, V82ML24I, K43KTT12P, I15S, G16R, K20RT, E34KN, E35D, M36I, N37K, R41N, K45KR, L63T, G68E, H69K, A71V, I72IT, T74A, Q92K, I93LC
 RenG11819RenG11819KT742847PINA  I15V, M36I, N37K, R41N, D60E, L63T, H69K, L89M, I93LC
 RenG11807RenG11807KT742835PINA  I15V, L19I, M36I, N37K, R41N, L63T, H69K, I93LC
 RenG12853RenG12853KT743881PINA  I15V, M36L, N37K, R41N, L63T, H69K, T74S, L89M, I93LC
 RenG13284RenG13284KT744312PINA  L10I, I13V, I15V, G16E, M36T, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG13127RenG13127KT744155PINA  I15V, M36I, N37K, R41N, L63T, H69K, I93LC
 RenG13007RenG13007KT744035PINA  T12P, I15V, E35D, M36I, N37K, R41N, Q61E, L63T, H69K, V82I, L89M, I93LC
 RenG11955RenG11955KT742983PINA V11VIT12A, I13IV, K14R, I15V, G16E, M36I, N37K, R41N, Q61K, L63T, H69K, L89I, I93LC
 RenG12462RenG12462KT743490PINAI54V, V82A L10IV, K14R, I15V, K20R, E35D, M36I, N37K, R41N, I62V, L63T, H69K, A71V, T74S, L89M, I93LC
 RenG11650RenG11650KT742678PINA  I15V, K20R, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG10989RenG10989KT742017PINAM46I, I54V, V82A I15V, K20R, E35ED, M36I, N37K, R41N, K55R, L63T, H69K, I72T, T74A, L89M, I93LC
 RenG11616RenG11616KT742644PINA  K14R, I15V, G16E, M36I, N37K, R41N, L63T, H69K, I72T, I93LC
 RenG11086RenG11086KT742114PINAM46I, I47A, I84VF53LL10V, G16E, E35D, M36V, N37E, P39S, R41N, I62V, L63T, H69R, A71V, T74S, L89M, I93LC
 RenG10417RenG10417KT741445PINA  I15V, L19I, N37K, R41N, L63T, H69K, T74A, V77I, L89M, I93LC
 RenG10565RenG10565KT741593PINA  P39T, K43R, L63T, H69K, L89I, I93LC
 RenG11494RenG11494KT742522PINAI50L, V82L, L90ML33F, K43TT12S, I13V, I15V, K20R, E35D, M36IV, N37K, R41N, Q61HN, L63T, I64V, H69K, A71V, T74S, L89M, I93LC
 RenG11773RenG11773KT742801PINA  I15V, K20R, M36I, N37K, R41N, K45KR, I62V, L63T, H69K, L89M, I93LC
 RenG10624RenG10624KT741652PINAL90MQ58EI13V, K14R, I15V, K20T, E35G, M36I, N37K, P39S, R41N, Q61N, L63T, I64IV, H69K, A71T, T74A, V82I, L89I, I93LC
 RenG11100RenG11100KT742128PINAI50L, V82MT74PI15V, G16E, L19Q, K20R, E35D, M36I, N37K, P39PS, R41N, K45R, L63T, H69K, A71V, I72IV, I93LC
 RenG10144RenG10144KT741172PINA  L10V, I13V, K14KR, G16E, K20R, M36I, N37K, R41N, D60DN, Q61QE, L63T, H69K, L89M, I93LC
 RenG11254RenG11254KT742282PINA  K14R, I15V, M36I, N37K, R41N, K45R, L63T, H69K, K70R, V82I, L89M, I93LC
 RenG10137RenG10137KT741165PINA  I15V, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG10527RenG10527KT741555PINA  L10V, I13V, I15V, K20R, M36I, N37K, R41N, I62V, L63T, H69K, T74A, L89M, I93LC
 RenG10978RenG10978KT742006PINAI54V, V82AL33F, T74PL10I, I13V, G16E, K20R, M36I, N37K, R41N, L63T, H69Q, L89M, I93LC
 RenG11088RenG11088KT742116PINAI54V, V82C, L90ML10F, L33F, T74PT12S, I13V, I15V, G16E, L19AV, K20M, D25DN, E35DN, M36I, N37K, R41N, Q61H, L63T, I66IM, H69K, L89M, I93LC
 RenG10631RenG10631KT741659PINAM46L, I54V, V82A, I84VV11I, L24I, K43TL10I, T12E, I13V, L19I, K20I, M36I, Q61N, L63T, I64V, H69K, A71V, I72IV, T74S, I93LC
Giandhari (2015)50792006_ZA_5079FKP056179RTV39  L10M, T12S, I15V, L19I, N37K, R41I, L63T, H69K, K70RC
Novitsky (2015)bcpp_203bcpp_203KR860688PINA  L10I, G16E, L19V, M36I, N37D, L63T, H69K, L89M, I93LC
 bcpp_068bcpp_068KR860631PINA  I15V, G17D, M36I, N37K, R41K, K45R, L63T, H69K, L89M, I93LC
 bcpp_046bcpp_046KR860620PINA  T12S, I15V, L19I, M36I, R41K, L63T, H69K, I93LC
 bcpp_245bcpp_245KR860706PINA  I15V, M36I, R41K, I62V, L63T, H69K, T74A, L89M, I93LC
 bcpp_087bcpp_087KR860637PINA  T12P, I15V, L19I, E35D, M36I, N37D, R41K, I62V, L63T, E65D, H69K, A71T, I93LC
 bcpp_261bcpp_261KR860709PINA  T12S, I15V, L19I, M36L, N37S, R41K, L63T, H69K, L89M, I93LC
 mpp_228mpp_228KR861008PINA  T12S, I15V, L19I, K20M, E35E_TN, M36L, L63T, H69K, I93LC
 bcpp_413bcpp_413KR860760PINA  T12S, I15V, L19I, E35D, M36I, R41K, K45R, R57K, D60E, L63T, H69K, V82I, L89M, I93LC
 bcpp_027bcpp_027KR860614PINA  T12S, I15V, L19I, E35D, M36I, L63T, H69K, L89M, I93LC
Rossouw (2015)RP030RP030KT032003LPV75  T12S, I15IV, Q18E, L19I, M36T, R41K, L63T, H69K, I93LC
 RP117RP117KT032042LPV182  T12S, I15V, L19T, M36I, R41K, L63T, E65D, H69K, L89M, I93LC
Sutherland (2015)1414_POSTKT351810LPV   T12P, I15V, G16E, L19I, M36I, L63T, H69K, I72V, I93LC
 1818_POSTKT351818LPV   T12S, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
Neogi (2016)419013.ZA.GT3123KT593370LPV   I15V, L19I, M36I, N37T, R41K, L63T, H69K, V82I, L89M, I93LC
 157213.ZA.GT3024KT593311LPV   T12S, L19I, M36I, N37S, R41K, L63T, H69K, T74S, L89M, I93LC
 714313.ZA.EC707KT592854LPV M46I, I54V, L76V, V82AL10F, L24I, L33FI13V, G16E, L19I, K20R, E35N, M36I, N37D, L63T, H69K, I72V, T74S, L89M, I93LC
 62113.ZA.NC005KT593441LPV   T12S, I15V, Q18E, L19I, K20R, E35D, M36I, R41K, R57RK, L63T, H69K, L89M, I93LC
 415513.ZA.GT2809KT593153LPV   T12S, I15V, G16E, L19T, R41K, L63T, H69K, V77I, I93LC
 443013.ZA.EC769KT592897LPV   T12S, I15V, L19V, N37NS, R57K, L63T, C67S, H69K, V77I, V82VI, L89MC
 99413.ZA.WC338KT593529LPV   I15V, L19I, E35D, M36I, R41K, R57K, L63T, H69K, T74S, V77I, L89M, I93LC
 11213.ZA.EC772KT592900LPV   K14R, I15V, G17D, L19I, M36IL, N37S, L63T, H69K, L89M, I93LC
 198613.ZA.GT3210KT593436LPV M46I, I54V, V82AL10F, Q58ET12S, I15V, G16GE, L19V, K20R, E35D, M36I, L63T, H69K, T74S, L89M, I93LC
Steegen (2016)GFMPB084GFMPB084KU128175LPV   T12S, I15V, G16E, L19I, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LC