<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63T
Rx >= 1 PI
IncludeMixtures No
References 26
Patients 161
Isolates 177
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Kantor (2002)TCDD-08TCDD-08_1AY090845SQV95  I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72IT, T74S, L89M, I93LC
Soares (2003)BR54BR54AY275730NFV56  T12A, I13V, G16E, L19I, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
Gomez-Carrillo (2004)9610596105AY365516PINA  T12A, I15S, G16R, E35D, M36I, N37K, R41N, L63T, H69K, I72T, T74S, L89M, I93LC
Grossman (2004)IL49IL49AY529530NFV64N88NS, L90LM Q7QK, L10LI, I15V, G16E, K20RT, E35D, M36I, L38LM, R41RK, R57K, L63T, H69K, T74TS, L89M, I93LC
 IL160IL160AY529612SQV, NFV128D30NN88DT12S, I15V, L19I, K20I, M36I, P39PS, R41K, K45R, L63T, H69K, A71IV, I93LC
 IL287IL287AY529620SQV, RTV, IDV, NFV184I84V, L90M L5LI, L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63T, H69K, A71V, T74S, I93LC
 IL433IL433aAY529600IDV117M46ML, V82A, L90LMQ58EL10C, I15V, K20R, M36I, K45KR, L63T, H69K, L89M, I93LC
 IL708IL708AY529608NFV44I84C I15V, K20R, M36I, R41K, L63T, H69K, I72T, I93LC
Non-B Workgroup (2005)UK973UK973AY900789NFV54  T12S, I15V, L19T, K20KT, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
 IL273IL273 NFV, IDV, RTV137  I15V, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 TK3020TK3020a RTV, NFV, SQV120  T12S, I15V, L19I, E35D, M36I, R41K, L63T, H69K, T74S, L89I, I93LC
 TK3022TK3022 SQV, NFV103  T12S, I15V, L19I, K20R, E35D, M36I, K43R, L63T, H69K, L89M, L97LIC
Rhee (2005)CA7907CA24813AY797580IDV, NFV260D30NL10F, N88DT12P, K14R, I15V, G16E, K20IT, E35G, M36V, R41K, L63T, H69Q, T74S, V77VI, I85IV, L89M, I93LC
Weber (2005)F36402F36402AY714443IDV, SQV, Unknown>65M46I, I84V, L90ML10F, T74PI15V, L19I, K20IMT, M36I, R41K, K43R, Q61H, I62V, L63T, I64V, H69K, L89M, I93LC
Baxter (2006)12-17161716-30421DQ876854PINAM46L, I54V, V82A, I84VL24I, L33F, K43TL10I, I15V, K20R, E35D, M36I, N37ND, R41K, I62V, L63T, H69K, T74S, L89M, I93LC
 12-31023102-30610DQ877250PINAL90ML23I, L33F, F53L, Q58EL10I, T12P, I15V, G16E, L19V, K20R, E35D, M36I, N37T, I62V, L63T, H69K, T74A, V82I, I85V, L89M, I93LC
Doualla-Bell (2006)Pt5FDB_Pt5 NFV N88SL10FI15V, L19I, K20T, E35D, M36I, R41K, Q61H, L63T, H69K, T74S, L89M, I93LC
 Pt7FDB_Pt7 NFV D30NL33FL10M, V11F, I13V, I15V, K20R, E35D, M36I, R41K, I62V, L63T, H69K, I93LC
Sen (2007)T009NPT9EF186927SQV, RTV   T12S, K14R, I15V, G16E, L19I, M36IV, R41K, Q61H, L63T, H69K, L89M, I93LC
  NPT9-PLEF186959SQV, RTV   T12S, K14R, I15V, G16E, L19I, M36V, R41K, Q61H, L63T, H69K, L89M, I93LC
von Wyl (2007)19702313EF449901PINAI54IV, N88NS, L90M L10V, T12K, I15V, G16E, L19I, K20R, E35D, M36IV, N37Q, P39Q, R41N, D60DN, Q61QH, I62V, L63T, H69K, A71AV, I72IT, T74A, L89M, I93LC
 374822080EF449879PINA  M36I, R41K, L63T, H69KN, T74S, L89M, I93LC
Marconi (2008)SW068SW068EU308079LPV23  I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
Pillay (2008)DR54DR54AY589907NFV, RTV   L19T, M36L, R41K, L63T, H69K, T74S, L89M, I93L, F99FLC
 DR9303ZA.DR93AY589932IDV, LPV M46I, L90M L10R, T12S, G17D, L19T, K20M, M36I, R41K, K55KR, L63T, H69K, I72T, L89M, I93LC
Riddler (2008)RG9485RG9485w19 LPV26  T12S, I15V, L19I, M36I, L63T, H69K, I93LC
Kandathil (2009)VL06_192VL06_192EU037774PINA  T12S, I15V, L19I, E35D, M36I, N37E, L63T, H69K, T74S, L76X, L89M, I93LC
 VL07_109VL07_109EU781834PINA  T12S, I15V, G16E, L19I, M36I, R41K, L63T, H69K, I93LC
 VL07_108VL07_108EU781837PINA  T12S, K14R, I15V, G16E, L19I, M36V, R41K, D60E, Q61E, L63T, H69K, I93LC
Kassaye (2009)TCDD-08TC08_2003FJ445719SQV210  I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72T, T74S, L89M, I93LC
  TC08_2004FJ445726SQV239  I15V, L19I, M36I, R41K, D60E, L63T, H69K, I72T, T74S, L89M, I93LC
Dau (2010)07762A07762AGU581866PINA  K14KR, I15V, K20KR, M36I, N37K, R41N, L63T, H69K, T74S, L89M, I93LC
El-Khatib (2010)Pat07911ZA_SAVE1255JF960529LPV   T12S, I15V, L19V, E35D, M36I, R41K, K45R, L63T, H69K, T74S, V82VI, L89M, I93LC
Rodrigues (2010)301_07BR07SC301GQ401314SQV, RTV, LPV M46L, G48V, I54V, V82SL24I, L33F, T74PL10V, I13V, I15V, G16E, K20M, E34Q, E35D, M36I, N37NKT, R41N, K55R, L63T, H69K, L89M, I93LC
 331_07BR07SC331GQ401326NFV   I15V, L19Q, M36I, N37K, R41N, D60E, L63T, H69K, L89M, I93LC
Barber (2012)6957669576JQ361677LPV I54V, V82AL10FT12S, I15V, L19I, M36I, R41K, L63T, H69K, L89M, I93LC
Van Zyl (2013)763762KC424271LPV183M46I, I54V, V82A T12TS, I15V, G16E, L19I, K20M, E35D, M36I, L63T, H69K, T74S, L89M, I93LC
  1445KC423150LPV235M46I, I54V, V82A T12S, I15V, G16E, L19I, K20M, E35D, M36I, L63T, H69K, T74S, L89M, I93LC
 80642KC424197LPV52  T12S, L19I, M36I, R41K, L63T, H69K, I93LC
 11311491KC423181LPV52L90M G17D, L19I, M36I, L63T, H69K, L89M, I93LC
 11691618KC423273LPV26  T12S, K14R, I15V, G16E, L19V, M36I, N37K, R41K, K43R, R57K, L63T, H69K, V82I, L89M, I93LC
 16371520KC423201LPV26  T12S, L19T, K20R, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 14221329KC423063LPV26  T12S, I15V, L19T, K20R, M36I, R41K, K43R, R57K, Q61N, L63T, E65D, H69K, I93LC
 13852410KC423695LPV26  T12S, K14R, I15V, L19I, M36I, R41K, L63T, H69K, V82I, L89M, I93LC
 17572422KC423703LPV26  T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, K45R, D60E, Q61E, I62V, L63T, H69K, L89M, I93LC
 950426KC424054LPV26  I15V, G16E, L19I, E35D, M36I, R41K, K45R, L63T, H69K, V82VI, L89M, I93LC
  544KC424130LPV27  I15V, G16E, L19I, E35DN, M36I, P39PT, R41K, K45R, L63T, H69K, L89M, I93LC
 9711093KC422873LPV104  T12S, I15V, L19I, M36I, R41K, K45R, L63T, H69K, L89M, I93LC
 1177240KC423694LPV26  L10I, I15V, L19I, M36I, P39PQ, R41K, L63T, H69Q, L89M, I93LC
 681320KC423983LPV26  T12S, I15V, L19I, K20R, M36I, R41K, L63T, H69K, L89M, I93LC
 905569KC424143LPV26  L10I, K14S, I15V, L19I, M36I, R41K, L63T, I64M, H69K, I72V, L89M, I93LC
 4502121KC423634LPV104 V11IL10I, I13V, G16E, Q18K, L19T, K20R, M36I, R41K, K43I, R57RK, L63T, H69K, L89M, I93LC
 82457KC424144LPV26  L10I, T12S, I15V, L19T, K20R, M36I, R41RK, D60DE, Q61E, I62IV, L63T, E65D, H69K, L89M, I93LC
 5212165KC423660LPV26  T12S, I15V, G17D, L19T, K20R, M36I, R41K, L63T, H69K, I93LC
 828946KC424387LPV52  T12S, I15V, G16E, L19I, M36I, N37NS, R41K, L63T, H69K, I72IT, L89M, I93LC
  2883KC423873LPV52  T12S, I15V, G16E, L19I, M36I, N37NS, R41K, L63T, H69K, I72IT, L89M, I93LC
  3005KC423928LPV53  T12S, I15V, G16E, L19I, M36I, R41K, L63T, H69K, L89M, I93LC
 1002865KC424321LPV104M46I, I54V, V82AL10FT12P, I15V, G16E, L19P, K20T, M36I, L63T, H69K, I93LC
  2427KC423704LPV208M46I, I54V, L76V, V82AL10FT12P, I15V, G16E, L19P, K20M, M36I, L63T, I64IV, H69K, L89M, I93LC
 8681762KC423385LPV209  K14N, I15V, G16E, L19T, K20R, M36I, L63T, H69K, L89I, I93LC
 16391905KC423504LPV26  L10I, T12S, I15V, L19I, M36I, R41K, L63T, H69Q, I72T, I93LC
 15332947KC423906LPV26  L10V, T12TS, K14KR, I15V, G16E, L19I, M36I, K45R, L63T, H69K, L89M, I93LC
 1562834KC424305LPV26  T12S, I15V, L19I, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
 1273649KC424200LPV26  T12S, I15V, L19I, M36L, N37S, R41K, L63T, C67F, H69K, L89M, I93LC
 758374KC424019LPV26  T12S, I15V, L19V, E35D, M36L, R41K, L63T, H69K, A71T, I93LC
 762354KC424004LPV26  K14R, I15V, G17D, L19I, K20R, M36I, P39S, R41K, L63T, E65D, H69K, I72T, L89M, I93LC
 940739KC424257LPV104  I15V, L19V, R41K, L63T, H69K, T74S, V77I, L89M, I93LC
  1295KC423037LPV157  I15V, L19V, R41K, L63T, H69K, T74S, V77I, L89M, I93LC
  1978KC423539LPV209  I15V, L19V, R41K, L63T, H69K, T74S, V77I, L89M, I93LC
 9783050KC423945LPV209  I13IV, L19T, K20R, M36I, R41K, L63T, H69K, I93LC
 1565384KC424028LPV26  K14N, I15V, L19R, M36I, N37D, R41K, D60DE, Q61QE, L63T, H69K, L89M, I93LC
 15052145KC423649LPV26  I15V, L19T, K20R, M36I, R41K, L63T, H69K, V75I, L89M, I93LC
 16511874KC423474LPV26  I15V, L19LV, K20R, M36I, N37Q, R41N, D60N, I62V, L63T, H69K, L89M, I93LC
 1026122KC422971LPV26  I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
 17321998KC423550LPV26  T12S, I15V, L19I, K20R, E35D, M36I, N37E, R41K, D60E, Q61E, I62V, L63T, G68E, H69K, L89M, I93LC
 15822753KC423813LPV26M46I, I54V, L76V, V82AL10FI13V, G16E, L19I, K20R, M36I, N37Q, R41K, D60E, L63T, H69K, L89M, I93LC
 844208KC423603LPV26  K14KR, I15IV, L19IT, M36I, N37D, L63T, H69K, T74S, L89M, I93LC
 1042736KC424255LPV26  T12S, I15V, L19I, M36I, N37S, R41K, L63T, H69K, L89M, I93LC
  1643KC423292LPV130  T12S, I15V, L19I, M36I, N37S, R41K, L63T, H69K, L89M, I93LC
 6531777KC423398LPV209  T12S, L19T, K20R, M36I, R41K, L63T, H69K, L89M, I93LC
 13001765KC423388LPV26  L10V, G16E, M36I, N37Q, R41K, D60E, L63T, H69K, I72V, I93LC
 1147640KC424196LPV26  I15V, L19T, K20R, M36I, R41K, L63T, H69K, V75I, L89M, I93LC
  1300KC423039LPV130  I15V, L19T, K20R, M36I, R41K, L63T, H69K, V75I, L89M, I93LC
 1361404KC423126LPV26  T12S, L19I, K20R, M36I, R41K, L63T, H69K, K70KR, L89M, I93LC
 152711KC423795LPV26  L10I, K14T, I15V, L19V, M36I, R41K, L63T, E65D, H69K, L89M, I93LC
 4153026KC423933LPV209I54IV, V82VAG48GET12S, I15IV, L19V, K20R, E35D, M36I, N37D, Q61E, I62IV, L63T, E65D, H69K, A71AV, I72V, T74S, L89M, I93LC
Grossman (2014)16281628KF134991LPV52 V11IR8T, P9T, L10I, I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
 4949KF135089NFV, LPV52I54V, V82A, L90ML10F, L33F, T74PI13V, I15V, G16E, K20MT, E35N, M36I, R41K, R57K, Q61QHKN, I62IV, L63T, H69K, A71V, I93LC
 101101KF134929IDV, LPV52  W6MR, T12S, K14Y, I15V, L19T, K20R, M36I, R41K, L63T, H69K, I93LC
  101KF134930IDV, LPV156M46L, V82AL10F, L33F, K43T, F53FL, T74PT12S, G16E, L19T, K20R, E35D, M36I, N37NY, R41K, K55R, L63T, E65ED, H69K, L89M, I93LC
 762762KF135137LPV52  T12S, I15V, L19V, M36I, R41K, L63T, H69K, L89M, I93LC
 11201120KF134953LPV52  I15V, M36I, R41K, L63T, H69K, L89LM, I93LC
 976976KF135172LPV52  K14R, I15V, L19I, M36I, N37D, R41K, L63T, H69K, L89M, I93LC
 311311KF135047LPV52 T74TPT12S, I15V, L19IT, K20KI, E35ED, M36I, Q61E, L63T, H69K, L89IM, I93LC
  311KF135048LPV148M46L, I47A T12S, I13IV, I15V, L19K, K20I, M36I, Q61E, L63T, H69K, T74S, L89I, I93LC
 805805KF135148SQV, LPV52M46I, I54IV, L76V, V82VAL10LFT12TS, I15V, G16E, L19I, K20T, E35D, M36I, R41K, L63T, H69K, I85IV, L89I, I93LC
 188188KF135010IDV, LPV52  K14T, I15V, K20R, M36I, R41RK, L63T, H69K, L89M, I93LC
 1313KF134975IDV, LPV52  T12A, M36I, R41K, L63T, H69K, L89M, I93LC
 160160KF134989SQV, LPV52D30NN88DT12V, L19I, K20I, M36I, R41K, K45R, L63T, H69K, A71V, I93LC
 260260KF135035IDV, LPV384I54V, V82A, L90ML10FI15V, G16E, K20M, M36I, R41K, I62V, L63T, H69K, A71V, T74TS, L89I, I93LC
 504504 IDV, LPV52  T12TA, I13V, K14KR, I15V, M36I, R41K, L63T, I64M, H69K, L89M, I93LC
 610610 NFV, IDV, LPV52M46I, I54V, V82A, L90ML10F, T74PST12S, I13V, I15V, L19Q, K20I, E35D, M36I, N37ND, R41K, Q61H, I62V, L63T, I64V, I66L, H69K, L89M, I93LC
  610 NFV, IDV, LPV69M46I, I54V, L76V, V82A, L90ML10FT12S, I13V, I15V, L19Q, K20I, E35D, M36I, R41K, Q61N, I62V, L63T, I64V, I66L, H69K, T74S, L89M, I93L, C95FC
Steegen (2014)12ZAKS33312ZAKS333KJ176612LPV   R41K, L63T, H69K, L89M, I93LC
 11ZAKS11111ZAKS111KJ176393LPV   R41K, L63T, I64IL, H69K, V82I, L89M, I93LC
 12ZAKS27112ZAKS271KJ176550LPV V82A R41K, K45R, L63T, H69K, T74S, L89M, I93LC
 11ZAKS17111ZAKS171KJ176452LPV M46I, I50V, I54V, V82A R41K, K55R, R57K, Q61H, L63T, H69K, A71V, I72K, T74S, L89M, I93LC
 12ZAKS28212ZAKS282KJ176561LPV I47A, V82C R41K, L63T, H69K, I93LC
Diaz (2015)RenG16936RenG16936KT747964PINA  L10I, G16E, N37K, R41IT, R57K, D60E, L63T, H69K, L89M, I93LC
 RenG17384RenG17384KT748412PINA  I15V, L19LI, K20R, M36I, N37K, R41N, R57RK, L63T, H69K, L89M, I93LC
 RenG17353RenG17353KT748381PINAM46I, I54V, L76V, V82AL10F, L33FI13V, K14KR, K20R, E35D, M36I, R41N, I62V, L63T, H69K, A71V, I72V, T74TA, L89M, I93LC
 RenG15849RenG15849KT746877PINA  I15V, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG17470RenG17470KT748498PINA  L10V, T12I, I15V, G16E, E35D, M36I, N37K, R41N, L63T, H69K, I72V, L89M, I93LC
 RenG16317RenG16317KT747345PINAM46I, I54V, V82AL10F, Q58E, T74P, N88GI15V, G16E, K20T, E21K, E35G, M36I, N37K, P39S, R41N, L63T, H69K, V77I, L89MC
 RenG16825RenG16825KT747853PINA  L10I, M36I, N37K, R41N, L63T, H69K, L89M, I93L, N98IC
 RenG16641RenG16641KT747669PINAM46I, I84V L10V, I15V, G16E, E35G, M36I, N37K, P39S, R41N, I62V, L63T, I64V, H69K, T74A, I85V, L89M, I93LC
 RenG16982RenG16982KT748010PINAM46L, I54IV, V82AL10LFPS, L23I, L33F, F53FLP9PR, T12I, I13V, I15V, G16E, M36L, N37K, R41R_N, G51A, D60E, I62LV, L63T, H69K, A71V, L89I, T91TA, I93LC
 RenG14027RenG14027KT745055PINAI54V, V82AK43KTI15V, G16E, K20R, E35D, M36IV, N37KT, P39PS, R41KN, D60E, Q61N, L63T, H69K, T74TA, V77VI, L89M, I93LC
 RenG14203RenG14203KT745231PINA  I15V, L19IV, M36I, N37K, R41N, L63T, H69K, V82I, I93LC
 RenG13952RenG13952KT744980PINA  I15V, M36I, N37K, R41N, K45R, L63T, H69K, L89M, I93LC
 RenG14874RenG14874KT745902PINAM46I, N88S I15V, K20T, E35D, M36I, N37K, R41N, L63T, I64IV, H69K, T74S, L89M, I93LC
 RenG15067RenG15067KT746095PINA  T12A, I13V, K14R, I15V, G16E, M36I, N37K, R41N, K45R, D60E, Q61N, L63T, H69K, L89I, I93LC
 RenG14451RenG14451KT745479PINA  L10I, L19I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG14721RenG14721KT745749PINA  W6G, L10I, M36I, N37E, R41N, D60N, L63T, H69K, L89M, I93LC
 RenG14536RenG14536KT745564PINAD30N, I54ILM, I84IVL10F, L33F, N88DI15V, G16E, K20T, E35D, M36I, N37EK, P39S, R41N, K45I, L63T, H69K, T74AS, I85V, L89M, I93ILC
 RenG14962RenG14962KT745990PINAM46I, I54V, V82AL10F, L24I, L33FI15V, G16E, L19Q, K20R, E35D, M36I, N37K, R41N, Q61H, L63T, H69K, L89I, Q92K, I93LC
 RenG13551RenG13551KT744579PINAM46MI, I50V, I54V, V82M, N88SL33F, Q58E, T74PL10V, G16E, K20R, E35D, M36I, N37K, R41N, R57RK, L63T, H69K, L89F, I93LC
 RenG15224RenG15224KT746252PINA  M36I, N37K, R41N, L63T, H69K, I72T, T74S, L89M, I93LC
 RenG14258RenG14258KT745286PINA  L10V, I15V, G16A, M36I, N37K, R41N, I62V, L63T, H69K, T74A, L89M, I93LC
 RenG15313RenG15313KT746341PINAM46L, G48A, I54V, V82A, L90ML33F, N83DL10V, K14KR, I15IV, G16E, K20R, E35D, M36I, N37K, R41N, R57K, Q61N, L63T, H69K, T74S, I85V, L89I, Q92K, I93LC
 RenG14857RenG14857KT745885PINA  I15V, G16E, M36T, N37K, R41N, L63T, H69K, L89I, I93LC
 RenG14092RenG14092KT745120PINA  T12P, K14KR, I15V, G16E, N37R, R41N, D60E, Q61D, L63T, H69K, I72K, L89M, I93LC
 RenG14739RenG14739KT745767PINA  M36I, R41H, D60E, L63T, H69K, L89M, I93LC
 RenG15422RenG15422KT746450PINA  L10M, I15IV, L19LI, N37K, R41N, L63T, H69K, I93LC
 RenG15333RenG15333KT746361PINA  L10V, G16E, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG12208RenG12208KT743236PINA  I13V, M36I, N37K, R41N, D60E, Q61DN, L63T, H69K, L89M, I93LC
 RenG13483RenG13483KT744511PINA  T12N, I15V, N37K, R41N, D60E, L63T, H69K, L89MC
 RenG13267RenG13267KT744295PINA  T12A, K14R, I15V, G16E, M36I, N37K, R41N, Q61KN, L63T, H69K, L89I, I93LC
 RenG13457RenG13457KT744485PINA  L10V, I13IV, K14KNRS, L19I, K20KR, M36I, N37K, R41N, L63T, H69K, L89MC
 RenG13229RenG13229KT744257PINA  T12TA, I15S, G16R, M36I, N37K, R41N, Q61QH, L63T, H69K, I72IT, L89M, I93LC
 RenG13433RenG13433KT744461PINAI50L, V82ML24I, K43KTT12P, I15S, G16R, K20RT, E34KN, E35D, M36I, N37K, R41N, K45KR, L63T, G68E, H69K, A71V, I72IT, T74A, Q92K, I93LC
 RenG11819RenG11819KT742847PINA  I15V, M36I, N37K, R41N, D60E, L63T, H69K, L89M, I93LC
 RenG11807RenG11807KT742835PINA  I15V, L19I, M36I, N37K, R41N, L63T, H69K, I93LC
 RenG12853RenG12853KT743881PINA  I15V, M36L, N37K, R41N, L63T, H69K, T74S, L89M, I93LC
 RenG13284RenG13284KT744312PINA  L10I, I13V, I15V, G16E, M36T, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG13127RenG13127KT744155PINA  I15V, M36I, N37K, R41N, L63T, H69K, I93LC
 RenG13007RenG13007KT744035PINA  T12P, I15V, E35D, M36I, N37K, R41N, Q61E, L63T, H69K, V82I, L89M, I93LC
 RenG11955RenG11955KT742983PINA V11VIT12A, I13IV, K14R, I15V, G16E, M36I, N37K, R41N, Q61K, L63T, H69K, L89I, I93LC
 RenG12462RenG12462KT743490PINAI54V, V82A L10IV, K14R, I15V, K20R, E35D, M36I, N37K, R41N, I62V, L63T, H69K, A71V, T74S, L89M, I93LC
 RenG11650RenG11650KT742678PINA  I15V, K20R, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG10989RenG10989KT742017PINAM46I, I54V, V82A I15V, K20R, E35ED, M36I, N37K, R41N, K55R, L63T, H69K, I72T, T74A, L89M, I93LC
 RenG11616RenG11616KT742644PINA  K14R, I15V, G16E, M36I, N37K, R41N, L63T, H69K, I72T, I93LC
 RenG11086RenG11086KT742114PINAM46I, I47A, I84VF53LL10V, G16E, E35D, M36V, N37E, P39S, R41N, I62V, L63T, H69R, A71V, T74S, L89M, I93LC
 RenG10417RenG10417KT741445PINA  I15V, L19I, N37K, R41N, L63T, H69K, T74A, V77I, L89M, I93LC
 RenG10565RenG10565KT741593PINA  P39T, K43R, L63T, H69K, L89I, I93LC
 RenG11494RenG11494KT742522PINAI50L, V82L, L90ML33F, K43TT12S, I13V, I15V, K20R, E35D, M36IV, N37K, R41N, Q61HN, L63T, I64V, H69K, A71V, T74S, L89M, I93LC
 RenG11773RenG11773KT742801PINA  I15V, K20R, M36I, N37K, R41N, K45KR, I62V, L63T, H69K, L89M, I93LC
 RenG10624RenG10624KT741652PINAL90MQ58EI13V, K14R, I15V, K20T, E35G, M36I, N37K, P39S, R41N, Q61N, L63T, I64IV, H69K, A71T, T74A, V82I, L89I, I93LC
 RenG11100RenG11100KT742128PINAI50L, V82MT74PI15V, G16E, L19Q, K20R, E35D, M36I, N37K, P39PS, R41N, K45R, L63T, H69K, A71V, I72IV, I93LC
 RenG10144RenG10144KT741172PINA  L10V, I13V, K14KR, G16E, K20R, M36I, N37K, R41N, D60DN, Q61QE, L63T, H69K, L89M, I93LC
 RenG11254RenG11254KT742282PINA  K14R, I15V, M36I, N37K, R41N, K45R, L63T, H69K, K70R, V82I, L89M, I93LC
 RenG10137RenG10137KT741165PINA  I15V, M36I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG10527RenG10527KT741555PINA  L10V, I13V, I15V, K20R, M36I, N37K, R41N, I62V, L63T, H69K, T74A, L89M, I93LC
 RenG10978RenG10978KT742006PINAI54V, V82AL33F, T74PL10I, I13V, G16E, K20R, M36I, N37K, R41N, L63T, H69Q, L89M, I93LC
 RenG11088RenG11088KT742116PINAI54V, V82C, L90ML10F, L33F, T74PT12S, I13V, I15V, G16E, L19AV, K20M, D25DN, E35DN, M36I, N37K, R41N, Q61H, L63T, I66IM, H69K, L89M, I93LC
 RenG10631RenG10631KT741659PINAM46L, I54V, V82A, I84VV11I, L24I, K43TL10I, T12E, I13V, L19I, K20I, M36I, Q61N, L63T, I64V, H69K, A71V, I72IV, T74S, I93LC
Novitsky (2015)bcpp_203bcpp_203KR860688PINA  L10I, G16E, L19V, M36I, N37D, L63T, H69K, L89M, I93LC
 bcpp_068bcpp_068KR860631PINA  I15V, G17D, M36I, N37K, R41K, K45R, L63T, H69K, L89M, I93LC
 bcpp_046bcpp_046KR860620PINA  T12S, I15V, L19I, M36I, R41K, L63T, H69K, I93LC
 bcpp_245bcpp_245KR860706PINA  I15V, M36I, R41K, I62V, L63T, H69K, T74A, L89M, I93LC
 bcpp_087bcpp_087KR860637PINA  T12P, I15V, L19I, E35D, M36I, N37D, R41K, I62V, L63T, E65D, H69K, A71T, I93LC
 bcpp_261bcpp_261KR860709PINA  T12S, I15V, L19I, M36L, N37S, R41K, L63T, H69K, L89M, I93LC
 mpp_228mpp_228KR861008PINA  T12S, I15V, L19I, K20M, E35E_TN, M36L, L63T, H69K, I93LC
 bcpp_413bcpp_413KR860760PINA  T12S, I15V, L19I, E35D, M36I, R41K, K45R, R57K, D60E, L63T, H69K, V82I, L89M, I93LC
 bcpp_027bcpp_027KR860614PINA  T12S, I15V, L19I, E35D, M36I, L63T, H69K, L89M, I93LC
Rossouw (2015)RP030RP030KT032003LPV75  T12S, I15IV, Q18E, L19I, M36T, R41K, L63T, H69K, I93LC
 RP117RP117KT032042LPV182  T12S, I15V, L19T, M36I, R41K, L63T, E65D, H69K, L89M, I93LC