<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63S
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 9
Isolates 9
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG5959_w32 NFV32 L76LFI13V, M36I, R41K, L63S, I64IL, H69K, L89M, I93LC
Grossman (2004)IL574IL574AY529605NFV56D30N Q7H, R8A, I15V, L19I, K20T, M36I, N37S, R41K, L63S, H69K, I93LC
Non-B Workgroup (2005)UK449UK449 SQV, NFV, RTV L90ML23IT12S, L19I, E35D, M36I, R41K, D60E, L63S, H69K, V82I, L89M, I93L, L97XC
 TK3031TK3031 SQV, NFV203D30NN88DI15V, L19I, K20T, E35G, M36I, R41K, G51GR, L63S, H69K, T74A, L89M, I93LC
 TK5010TK5010 RTV, IDV27  I13V, I15V, L19I, M36I, N37D, R57K, L63S, H69K, L89MC
 PL3670560970 IDV98V82A, L90LMT74PL10I, T12TS, I15V, L19I, K20KR, M36I, N37NS, R41K, K45R, Q61N, L63S, H69K, I72V, L89M, I93LC
Weber (2005)M36208M36208AY714457NFV, Unknown>69  I15V, L19I, M36L, R41K, L63S, H69K, L89M, I93LC
von Wyl (2007)1017278778EF449991RTV, PINA  L10V, L19I, M36I, L63S, H69K, I72V, L89M, I93LC
Riddler (2008)RG49532RG49532w9 LPV2  T12S, I15V, L19I, M36I, R41K, D60E, L63S, H69K, L89I, I93LC

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