<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63Q
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 24
Isolates 30
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Grossman (2004)IL217IL217AY529576NFV104D30NN88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, I64IV, H69Q, L89IM, I93LC
Weber (2005)F77878F77878AY677381Unknown, NFV>133L90M G17D, K20R, E35D, M36I, L63Q, I64V, H69K, L89M, I93LC
Doualla-Bell (2006)Pt8FDB_Pt8 NFV D30NL33F, N88DT12S, I15V, G16E, L19I, M36L, R41K, L63Q, H69K, L89IC
El-Khatib (2010)Pat12711ZA_SAVE2466JF960577LPV   T12S, I15V, L19I, R41K, L63Q, H69K, T74A, V77I, L89M, I93LC
Van Zyl (2013)93111.ZA.WC173KC423554LPV   T12S, I15IV, G16E, L19I, M36MI, R41K, K43R, L63Q, H69K, V77I, V82I, L89I, I93LC
 397312.ZA.GT2227KC423895LPV   T12S, I15V, L19I, M36I, R41K, L63Q, I64L, H69K, I93LC
 220911.ZA.GT1520KC423305LPV   I15V, L19I, M36I, R41K, L63Q, H69K, I93LC
 524606.ZA.GT006KC423883LPV   T12S, I15V, L19I, M36I, L63Q, H69K, I93LC
 23511.ZA.GT1949KC423729LPV   I15V, L19I, M36I, N37D, R41K, L63Q, H69K, L89M, I93LC
 304707.ZA.GT110KC424172LPV   T12S, I15V, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  07.ZA.GT345KC424138LPV   T12S, I15V, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  08.ZA.GT542KC423852LPV   T12S, I15V, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  09.ZA.GT993KC422850LPV   T12S, I15IV, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  10.ZA.GT1219KC423055LPV   T12S, I15V, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  11.ZA.GT1634KC423429LPV   T12S, I15IV, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
 307308.ZA.GT416KC424179LPV   T12S, I15V, L19I, R41K, L63Q, H69K, T74AS, V77I, L89M, I93LC
Grossman (2014)448448KF135078IDV, LPV52  T12P, I15V, M36I, R41K, L63Q, H69K, L89M, I93LC
 217217KF135024NFV, LPV52D30N, I54V, V82AL33F, N88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, H69Q, V75I, L89I, I93LC
 849849KF135153NFV, LPV52V82A I15V, G16E, K20KR, M36I, R41K, L63Q, H69K, L89M, I93LC
  849KF135154NFV, LPV134M46I, I54V, L76V, V82AL10F, L33FI13V, I15V, G16E, K20R, M36I, R41K, L63Q, H69K, L89I, I93LC
Diaz (2015)RenG15347RenG15347KT746375PINA  K14KR, I15V, G16E, K20KR, D25DN, E35D, M36I, N37K, R41N, L63Q, H69K, L89M, I93LC
 RenG12704RenG12704KT743732PINA  T12P, I13V, K14R, I15V, M36I, N37K, R41N, L63Q, I64M, H69K, L89M, I93LC
 RenG11901RenG11901KT742929PINA  I13V, I15V, M36I, N37K, R41N, K43KR, I62V, L63Q, H69K, T74A, L89M, I93LC
 RenG11098RenG11098KT742126PINAD30NN88DI13V, K14KR, I15V, K20T, E35D, M36I, N37Q, R41NS, D60E, Q61N, L63Q, H69K, T74A, V77VI, L89M, I93LC
 RenG10600RenG10600KT741628PINA L33FT12TAP, I13V, K14KR, M36I, N37K, P39S, R41N, I62V, L63Q, I64M, H69K, T74A, L89M, I93LC
 RenG11404RenG11404KT742432PINAM46I, I54V, V82AV11I, L24I, L33FL10V, I13V, I15V, K20R, E35D, M36I, N37NK, R41P, K45KR, I62V, L63Q, G68DE, H69K, A71I, L89T, I93LC
Novitsky (2015)bcpp_174bcpp_174KR860673PINA  T12S, I15V, G16E, L19I, M36I, R41K, L63Q, H69K, L89M, I93LC
Neogi (2016)61613.ZA.EC689KT592845LPV   I13IV, K14KR, N37S, R41K, R57K, L63Q, I64V, H69HY, V77IC
 554913.ZA.EC643KT592813LPV   I15V, L19IT, M36I, L63Q, H69K, I93LC
 353213.ZA.GT3136KT593381LPV   K14R, I15V, M36I, R41K, L63Q, H69K, I93LC