<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63Q
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 14
Isolates 20
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Grossman (2004)IL217IL217AY529576NFV104D30NN88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, I64IV, H69Q, L89IM, I93LC
Weber (2005)F77878F77878AY677381Unknown, NFV>133L90M G17D, K20R, E35D, M36I, L63Q, I64V, H69K, L89M, I93LC
Doualla-Bell (2006)Pt8FDB_Pt8 NFV D30NL33F, N88DT12S, I15V, G16E, L19I, M36L, R41K, L63Q, H69K, L89IC
El-Khatib (2010)Pat12711ZA_SAVE2466JF960577LPV   T12S, I15V, L19I, R41K, L63Q, H69K, T74A, V77I, L89M, I93LC
Van Zyl (2013)14862923KC423895LPV26  T12S, I15V, L19I, M36I, R41K, L63Q, I64L, H69K, I93LC
 342492KC423729LPV26  I15V, L19I, M36I, N37D, R41K, L63Q, H69K, L89M, I93LC
 6551659KC423305LPV26  I15V, L19I, M36I, R41K, L63Q, H69K, I93LC
 836556KC424138LPV26  T12S, I15V, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  61KC424172LPV27  T12S, I15V, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  284KC423852LPV78  T12S, I15V, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  1064KC422850LPV130  T12S, I15IV, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  1320KC423055LPV182  T12S, I15V, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
  1813KC423429LPV235  T12S, I15IV, L19I, R41K, L63Q, H69K, T74S, V77I, L89M, I93LC
 859617KC424179LPV26  T12S, I15V, L19I, R41K, L63Q, H69K, T74AS, V77I, L89M, I93LC
 82029KC423883LPV26  T12S, I15V, L19I, M36I, L63Q, H69K, I93LC
 17252001KC423554LPV26  T12S, I15IV, G16E, L19I, M36MI, R41K, K43R, L63Q, H69K, V77I, V82I, L89I, I93LC
Grossman (2014)448448KF135078IDV, LPV52  T12P, I15V, M36I, R41K, L63Q, H69K, L89M, I93LC
 217217KF135024NFV, LPV52D30N, I54V, V82AL33F, N88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, H69Q, V75I, L89I, I93LC
 849849KF135153NFV, LPV52V82A I15V, G16E, K20KR, M36I, R41K, L63Q, H69K, L89M, I93LC
  849KF135154NFV, LPV134M46I, I54V, L76V, V82AL10F, L33FI13V, I15V, G16E, K20R, M36I, R41K, L63Q, H69K, L89I, I93LC