Protease Inhibitors

HOME Genotype-Rx Genotype-Pheno Genotype-Clinical hivdb program

Protease Inhibitors

Subtype	C
Gene	PR
Mutation	L63P
Rx	>= 1 PI
IncludeMixtures	No

References	31
Patients	185
Isolates	223

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	Wks	PIMajorDRMs	PIMinorDRMs	OtherMut	Subtype
Gonzales (2001)	CA4490	CA11062	AF331699	SQV	14			T12S, I15V, L19I, M36I, R41K, K45KR, L63P, H69K, L89LM, I93L	C
Gibb (2002)	DMG104	104_w66		NFV	66	N88S	Q58QE	T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, D60E, Q61E, L63P, H69K, L89M, I93L	C
	DMG59	59_w7		NFV	7		K43T	T12S, I15V, L19I, M36I, R41K, I62V, L63P, I64M, H69K, L89M, I93L	C
	DMG78	78_w9		NFV	9	D30DN, L90LM	L89MV	T12S, I15V, L19I, E35D, M36L, N37E, D60E, L63P, I64IV, H69K, I93L	C
		78_w30		NFV	30	D30N	N88ND, L89MV	T12S, I13IV, I15V, L19I, E35D, M36L, N37E, K45KQR, D60E, L63P, H69K, I93L	C
	DMG80	80_w32		NFV	32			T12S, I15V, L19V, M36I, N37NS, R41K, R57K, L63P, H69K, I72IL, I93L	C
	DMG83	83_w4		NFV	4			T12S, I15V, L19I, M36L, R41K, D60E, L63P, H69K, L89M, I93L	C
		83_w31		NFV	31			T12S, I15V, L19I, M36L, R41K, D60E, L63P, H69K, L89M, I93L	C
		83_w49		NFV	49			T12S, I15V, L19I, M36L, R41K, D60E, L63P, H69K, L89M, I93L	C
	DMG85	85_w29		NFV	27			T12S, I15V, L19I, E35D, M36I, R41K, K45R, D60E, Q61E, L63P, H69K, L89M, I93L	C
	DMG86	86_w82		NFV	65	D30N	L10F, N88D, L89V	T12S, I13V, I15V, L19I, E35D, M36L, N37E, K45R, D60E, L63P, H69K, I93L	C
	DMG91	91_w22		NFV	22	D30N	L10F, N88D, L89V	T12S, I13V, I15V, L19I, E35D, M36L, N37E, K45R, D60E, L63P, H69K, I93L	C
	DMG95	95_w75		NFV	75			I15V, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L	C
Kantor (2002)	TCDD-04	TCDD-04	AY090843	NFV, APV	38			T12S, I15V, L19I, D25DN, M36I, R41K, L63P, H69K, I93L	C
	TCDD-05	TCDD-05_1	AY090844	SQV	38	L90M		T12S, I15V, L19I, M36I, R41K, L63P, H69K, A71V, I93L	C
	TCDD-28	TCDD-28_1	AY090854	SQV	279	L90M	G73GS	I15V, L19I, M36I, R41K, L63P, H69K, A71V, I93L	C
	TCDD-29	TCDD-29	AY090855	SQV	140	L90M		I15V, G16E, K20KR, E21EK, E35D, M36I, P39S, R41K, K45R, D60E, L63P, H69K, A71AV, L89M, I93L, F99X	C
	TCDD-23	TCDD-23_1	AY090850	SQV	205	L90M		I15V, L19I, M36I, R41K, D60E, L63P, H69K, V82I, L89M, I93L	C
Snoeck (2002)	BE16a	BE16a	AF339009	IDV	107	M46I, V82A	L24I	L10IM, T12TS, I15V, L19T, M36I, R41K, K43KN, R57RS, D60E, Q61E, L63P, H69K, L89M, I93L	C
Johnston (2003)	TC-59	TC-59		APV	47			T12S, I15V, L19I, M36I, R41K, L63P, H69K, V82VI, L89M, I93L	C
	TC-60	TC-60		IDV	104	I54IV, V82A		I15V, E35D, M36I, R41K, L63P, H69K, A71AT, I93L	C
Shafer (2003)	A384_3441	3441b	EF549036	NFV	32			T12S, I15V, L19T, K20R, M36L, R41K, L63P, H69K, I93L	C
Soares (2003)	BR58	BR58	AY275748	NFV	163			I15V, M36I, N37K, R41N, L63P, H69K, I93L	C
	BR61	BR61	AY275752	NFV	221			K14R, I15V, M36I, N37K, R41N, L63P, H69K, L89M, I93L	C
Colonno (2004)	RC-034-076-586	076-5861	AY461502	ATV		I50L		T12S, I15V, L19I, M36I, R41K, K45N, L63P, H69K, L89M, I93L	C
Grossman (2004)	IL81	IL81	AY529533	NFV	13			I15V, M36I, R41K, L63P, H69K, L89M, I93L	C
	IL128	IL128d	AY529544	NFV	65	D30DN		I15IK, E35D, M36I, R41K, L63P, I64IL, E65ED, H69K, L89M, I93L	C
	IL201	IL201a	AY529564	IDV	16			L10I, T12S, I15V, L19T, M36I, R41K, L63P, I64L, H69K, K70KE, L89M, I93L	C
		IL201c	AY529566	IDV	83			L10I, T12S, I15V, L19T, M36I, L63P, I64L, H69K, L89T, I93L	C
	IL178	IL178	AY529547	NFV	65	N88S		L19KT, K20T, T31TK, E35D, M36I, R41K, K45KR, L63P, H69K, L89M, I93L	C
	IL210	IL210a	AY529570	NFV	2			T12S, K14KE, I15V, L19LI, M36I, R41K, L63P, H69K, I93L	C
		IL210b	AY529571	NFV	55			T12S, I15V, G17X, L19LI, M36I, R41K, L63P, H69K, I93L	C
	IL255	IL255	AY529613	SQV, NFV	125	D30DN	N88ND	T12S, I15V, L19IT, E35ED, M36I, R41RK, P44PL, R57RK, L63P, H69K, T74TS, L89M, I93L, F99FI	C
	IL266	IL266	AY529621	SQV, RTV, IDV, NFV	180	I54IL, I84V, L90M	T74TP	R8RG, L10I, I15V, K20KI, E35EG, M36I, R41RK, L63P, H69K, A71V, L89M, Q92QR, I93L	C
	IL280	IL280a	AY529617	SQV, IDV	180	I84V, L90M		T12S, I15V, K20KR, M36I, R41RK, L63P, H69K, A71V, T74S, L89M, I93L	C
		IL280b	AY529616	SQV, IDV	201	M46MI, I84V, L90M		T12S, I15V, Q18L, D29DG, M36I, R41RK, L63P, H69KR, A71V, T74S, R87RT, L89M, I93L	C
	IL282	IL282	AY529581	NFV	18			T12S, I13IM, I15V, L19T, E35ED, M36I, L38LM, R41K, L63P, H69K, L89M, I93L	C
	IL384	IL384a	AY529618	IDV, SQV, RTV, NFV	154	M46I, I54V, V82A, L90M	T74P	W6WL, L10V, I15V, K20KI, M36I, N37D, R41K, L63P, H69K, A71V, L89M, I93L	C
		IL384b	AY529622	IDV, SQV, RTV, NFV	239	M46I, I54V, V82A, L90M	T74P	L10V, I15V, M36I, N37D, R41K, K55R, I62V, L63P, H69K, A71V, L89M, I93L	C
	IL400	IL400	AY529595	NFV	2			T12S, K14R, I15V, M36I, R41K, D60E, L63P, H69K, L89M, I93L	C
	IL401	IL401	AY529596	NFV	209	L90LM		L10R, V11F, K14R, D29DV, E35D, M36V, N37ND, R41K, L63P, I64IV, H69K, I72IV, L89LM, I93L	C
	IL665	IL665	AY529607	NFV	70			L10LP, V11C, I15V, M36I, R41K, K45R, L63P, H69K, I72IL, L89M, I93L	C
	IL719	IL719	AY529609	NFV	149			T12S, I15V, L19I, M36I, L38LM, R41K, L63P, H69K, I93L	C
Montes (2004)	MB_patCOU	02_COUL707	AJ577870	SQV, RTV, IDV, NFV	221	L90M	G73S	L10I, T12S, I15V, K20T, M36I, R41K, L63P, H69K, A71V, I93L	C
	MB_patMAU	01_MAU717	AJ577947	SQV	90			T12S, I15V, L19I, M36T, R41K, L63P, H69K, I72V, I93L	C
Snoeck (2004)	BE13b	BE13b	AY900730	IDV	44	M46I	L24I	T12S, I15V, L19I, M36I, N37K, R41N, K45R, L63P, H69K, L89T, I93L	C
Non-B Workgroup (2005)	UK231	UK231	AY900765	RTV, NFV	26	L90M	L33I, K43T	Q18L, L19T, K20X, E35N, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, L89M, I93L	C
	UK243	UK243	AY900766	IDV, NFV		L90M	L23I	T12S, I15V, L19I, E35G, M36I, R41K, L63P, H69K, K70R, V82I, I93L	C
	UK258a	UK258a	AY900767	SQV, RTV				I15V, M36I, N37D, D60E, L63P, H69K, L89M, I93L	C
	UK276	UK276	AY900768	IDV, SQV, NFV	52	L90M		L10IV, T12S, I13V, I15V, L19I, K20T, M36I, Q61E, L63P, I64L, H69K, L89M, I93L, C95F	C
	UK356b	UK356b	AY900770	NFV, RTV	44			T12S, I15V, L19I, M36L, R41K, D60E, L63P, H69K, L89M, I93L	C
	UK445	UK445	AY900772	IDV, RTV				T12S, K14R, I15V, L19I, M36I, R41K, L63P, H69K, L89I, I93L	C
	UK456b	UK456b	AY900773	NFV, IDV, RTV		M46I, L90M		L10LI, T12S, L19I, K20I, M36I, R41K, L63P, I64V, H69K, A71V, T74S, L89M, I93L	C
	UK496b	UK496b	AY900776	NFV		L90M		T12S, I13V, L19I, K20T, M36I, R41K, D60E, L63P, I64V, H69K, L89M, I93L	C
	UK512	UK512		SQV, RTV	20			T12P, I15V, L19I, M36I, N37S, R41K, L63P, H69K, L89M, I93L	C
	UK538	UK538		SQV, RTV	4			V11X, T12S, I15V, L19T, K20R, M36I, R41K, D60E, L63P, H69K, V77I, L89M, I93L	C
	UK624	UK624		PI	NA	I54V		T12S, I15V, L19I, K20R, M36I, R41K, L63P, H69K, I93L	C
	UK881	UK881		SQV, RTV, Unknown	>34			T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
	UK955	UK955	AY900786	SQV, RTV, IDV	137	I54V, I84V, L90M	G73S, L89V	L10I, I15V, L19I, K20X, E35D, M36I, R41K, D60E, I62IV, L63P, H69K, A71V, I85V, I93L	C
	UK1125	UK1125	AY900793	RTV, IDV	15			T12S, I15V, Q18X, L19T, M36I, R41K, L63P, H69K, I93L	C
	UK1147	UK1147	AY900794	IDV, NFV	117	M46I	K43T	T12S, I15V, L19I, K20T, E35D, M36I, N37D, D60E, Q61E, L63P, H69K, A71T, L89T, I93L	C
	UK1154	UK1154	AY900795	NFV		L90M		T12S, I13V, I15V, L19I, K20T, E35D, M36I, R41K, D60E, L63P, I64V, H69K, V82I, L89M, I93L	C
	IL80	IL80	AY900811	RTV, NFV, SQV	114	I54V, V82A, I84V	K43T	W6WL, T12S, L19I, K20R, E21EG, M36I, G40E, R41K, L63P, H69K, A71V, T74A, I93L	C
	IL201	IL201d	AY900813	IDV, RTV	123	L90M		T12S, I15V, L19T, M36I, R41K, L63P, I64IL, H69K, I85V, L89M, I93L	C
	IL257	IL257	AY900818	IDV, RTV	110	V82A		L10I, I15V, L19I, D29DV, M36I, R41K, L63P, H69K, I85V, I93L	C
	UK2062	UK2062		IDV, Unknown	NA			T12TS, I15V, L19IV, M36I, L63P, I64L, H69K, I93L	C
	BR6	BR6	AY900885	SQV, RTV, IDV	306	I54V, I84V, L90M	L89V	L10V, I13V, I15V, G16A, K20M, E35D, M36I, N37K, R41N, D60E, L63P, H69K, A71V, I93L	C
	BR42	BR42	AY900895	NFV	97	M46I, L90M		L10V, E35D, M36I, N37K, R41N, L63P, I64V, H69K, L89M	C
	TK1004	TK1004		NFV, RTV, IDV	131			I3IV, T12P, I15V, L19I, K20T, E21G, E35D, M36I, N37D, R41K, K45R, L63P, I64L, H69K, T74A, L89M, I93L	C
		TK1004a		NFV, RTV, IDV	183			T12P, I15V, L19I, K20T, E35D, M36I, N37D, R41K, K45R, L63P, I64L, H69K, T74S, L89M, I93L	C
		TK1004b		NFV, RTV, IDV	196			T12P, I15V, L19I, K20T, L24LF, E35D, M36I, N37D, R41K, K45R, L63P, I64L, H69K, T74S, L89M, I93L	C
		TK1004c		NFV, RTV, IDV	268			T12P, I15V, L19IT, K20T, E35D, M36I, N37D, R41K, K45R, L63P, I64L, H69K, T74S, L89M, I93L	C
	TK1020	TK1020		SQV, RTV, IDV	211	I54V, V82C, L90M	F53L	L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55H, L63P, H69K, T74A, L89M, I93L	C
		TK1020a		SQV, RTV, IDV, LPV	229	M46L, I54V, V82C, L90M	L23I, F53L	L10I, I15V, L19I, K20R, E35D, M36I, N37D, K55H, L63P, H69K, T74A, L89M, I93L	C
		TK1020b		SQV, RTV, IDV, LPV	392	M46I, I47V, I54V, V82C, L90M	L23I, K43T, F53L	L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55H, I62V, L63P, H69K, T74E, L89M, I93L	C
	TK1021	TK1021		IDV, RTV, LPV	331	M46I, I54V, V82A	L10F, L24I, Q58E	T12S, L19I, E35D, M36I, N37D, R41K, K55R, D60E, Q61E, I62V, L63P, H69K, L89M, I93L	C
		TK1021a		IDV, RTV, LPV	332	M46MI, I54IV, V82VA	L10LF, L24LI, Q58QE	T12S, I15IV, L19IV, E35D, M36I, N37D, R41K, K55KR, D60E, Q61E, I62IV, L63P, H69K, L89M, I93L	C
	TK2006	TK2006a		IDV, SQV, RTV	34			I15V, L19I, M36I, R41K, L63P, H69K, I93L	C
	TK2020	TK2020		SQV, RTV	250			T12S, I15V, L19V, M36V, R41K, L63P, I64L, H69K, L89M, I93L	C
	TK3007	TK3007a		RTV, IDV	43			T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
		TK3007b		RTV, IDV	58			T12S, I15V, L19M, E34A, M36I, R41K, L63P, H69K, L89M, I93L	C
		TK3007c		RTV, IDV	58		N83ND, L89MV	T12S, I15V, L19IM, E34A, M36I, R41K, L63P, H69K, I93L	C
	TK3009	TK3009		SQV, NFV	158	L90M		K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93L	C
		TK3009a		SQV, NFV, LPV	232	L90M		I13V, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93L	C
		TK3009b		SQV, NFV, LPV	232	L90M		I13IV, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93L	C
	TK3010	TK3010		SQV, NFV, RTV, IDV, LPV	177			T12S, I15V, L19I, K20T, M36I, R41K, L63P, H69K, L89M, I93L	C
		TK3010a		SQV, NFV, RTV, IDV, LPV	210			T12S, I15V, L19I, K20T, E35ED, M36I, R41K, L63P, H69K, L89M, I93L	C
	TK3013	TK3013		SQV, NFV	205	L90M	G73S	L10V, R41K, L63P, A71I, V77I, L89M, I93L	C
	TK3015	TK3015		SQV, IDV	204	I54V, V82A, L90M	K43T	L10I, T12S, I15V, L19I, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93L	C
		TK3015a		SQV, IDV, LPV	264	I54V, V82A, L90M	L10F, K43T	T12S, I15V, L19K, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93L	C
		TK3015b		SQV, IDV, LPV	283	I54V, V82A, L90M	L10F, K43T	T12P, I15V, L19K, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93L	C
		TK3015c		SQV, IDV, LPV, RTV, TPV	375	I54V, V82T, I84IV, L90M	K43T	L10I, T12S, I15V, L19I, K20IR, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, L89LM, I93L	C
	TK3019	TK3019		SQV, NFV, RTV	143	I54V, I84IV, L90M	V11VI, G73S	L10I, I13V, I15V, L19I, K20R, E35D, M36I, R41K, K45R, I62V, L63P, H69T, A71V, I72L, I93L	C
		TK3019a		SQV, NFV, RTV	149	L90M	G73S, T74AP	I15V, L19I, E35D, M36I, R41K, I62V, L63P, H69T, A71V, I72L, I93L	C
	TK3024	TK3024		SQV, NFV	205	L90M		T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, L63P, H69K, A71I, T74S, I93L	C
		TK3024a		SQV, NFV, LPV	246	L90M		T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45KR, L63P, H69K, A71I, T74S, I93L	C
	TK3026	TK3026		RTV, SQV, NFV	292	L90M		I15V, L19I, K20T, E35D, M36I, R41RK, L63P, H69K, A71I, T74S, L89I, I93L	C
	TK3027	TK3027		RTV, SQV, NFV	190	D30N, L90M	N88D	T12S, I13V, I15V, L19I, K20R, E35D, M36I, N37D, I62IV, L63P, H69K, T74S, L89I, I93L	C
		TK3027b		RTV, SQV, NFV, LPV	276	D30DN, L90LM	N88D	T12S, I13IV, I15V, L19I, K20R, E35D, M36I, N37ND, R41RK, L63P, H69K, T74S, L89IM, I93L	C
	TK3032	TK3032		SQV, IDV	239	M46I, I54V, V82T, L90M		L10R, T12S, I15V, L19I, K20R, E35D, M36I, R41K, I62V, L63P, G68GE, H69K, L89M, I93L, C95F	C
	TK3035	TK3035		IDV, NFV, RTV	202	I54A, V82A		L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K45KR, D60E, L63P, H69K, A71V, L89M, I93L	C
	TK4001	TK4001		NFV	2			T12S, I15V, L19T, M36I, R41K, Q61E, L63P, H69K, V82I, L89M, I93L	C
	TK4004	TK4004		IDV, SQV, RTV, NFV, LPV	278	M46I, L90M		L10R, I15V, L19I, K20M, M36I, R41K, L63P, H69K, K70R, L89M, I93L	C
	TK4011	TK4011		SQV, RTV, NFV, IDV	261	V82A, L90M	Q58E, G73S	L10V, T12S, I15V, L19I, K20R, M36I, L63P, H69K, A71V, I72L, I93L	C
	TK4017	TK4017		RTV, IDV	7			T12S, I15V, L19T, M36I, R41K, L63P, H69K, I93L	C
	TK5007	TK5007		IDV, RTV	261		G73ST	L10I, T12S, I15V, L19I, E35D, M36I, N37S, R41K, K45R, I62V, L63P, H69K, I85V, I93L	C
	K5009	TK5009		RTV, IDV	96	M46I, L76V, V82A	L10LF	T12S, I15V, L19I, K20KR, M36I, R41K, I62V, L63P, H69K, L89M, I93L	C
	PL27956	60622		NFV, RTV, IDV	184	L90MR		L10V, T12S, I15V, L19I, K20R, E35D, M36I, R41K, I62IV, L63P, H69K, A71AV, T74S, V77VI, I93L	C
	PL42056	72786		IDV, RTV	275	V82A	L10F, L24I, I54C	T12TS, I13IV, G17D, L19I, K20R, M36I, R41K, K45R, L63P, H69K, A71V, L89I, I93L	C
		91776		IDV, RTV, LPV	340	V82A	L10F, L24I, I54C	G17D, L19I, K20R, M36I, R41K, K45R, L63P, H69K, A71V, L89I, I93L	C
	PL47066	85002		IDV, NFV	104	D30N	N88D	T12S, I13V, I15V, L19I, E35ED, M36I, R41K, L63P, H69K, T74A, L89M, I93L	C
	PL4725	58294		Unknown, LPV	>4	G48V, I54V, V82T, L90M	Q58E	L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L	C
		69936		Unknown, LPV	>51	G48V, I54V, V82S, L90M	Q58E	L10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95CF	C
		80404		Unknown, LPV	>90	G48V, I54V, V82S, L90M	Q58E	L10V, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55R, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95F	C
		100703		Unknown, LPV, APV	>159	M46ML, G48V, I54V, V82S, L90M	V11VI, L33F, Q58E	L10V, I13V, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55R, I62V, L63P, H69K, K70KR, A71T, I72IM, T74S, I85V, L89I, I93L, C95F, T96S	C
	PL8338	77353		IDV, RTV	304	I54V, V82A		L10I, I13IV, I15V, L19I, M36L, R41K, I62V, L63P, I64V, H69K, L89M, I93L, C95F	C
Weber (2005)	M72003	M72003	AY677426	NFV, RTV, IDV	212	I54IV, L90M	L10F	I13V, K14N, I15V, L19I, K20T, E35N, M36I, R41K, K45R, I62IV, L63P, I64V, H69K, K70R, T74S, L89M, I93L	C
	00M3878	00M3878	AY677436	NFV	74			I15V, L19IV, M36I, R41K, K43R, D60DE, Q61QE, L63P, H69K, L89M, I93L	C
	F16446	F16446	AY677447	SQV, NFV, APV, LPV	208	M46I, I54V, I84V, L90M		L10I, T12S, L19I, K20M, M36I, R41K, D60E, L63P, H69K, L89M, I93L	C
	F56949	F56949	AY677453	NFV	154	D30N		T12S, I13V, I15V, L19I, K20T, M36I, R41K, K45T, L63P, H69K, I93L	C
	F30356	F30356	AY677479	Unknown, NFV	>201	I54V, V82A, L90M		L10I, T12S, I15V, L19T, K20R, E35D, M36I, N37H, P39PS, R41K, K45R, L63P, H69KQ, A71I, I93L	C
Baxter (2006)	12-1007	1007-30519	DQ875953	PI	NA	M46L, I54IV, V82A, L90M	L33F, K43KT	L10I, I15V, L19T, K20R, E35D, M36I, R41K, Q61E, I62IV, L63P, H69K, T74S, L89M, I93L	C
	12-3049	3049-30508	DQ876115	PI	NA	M46I, I54V, L76V, V82A, L90M	L10FI	W6W*, I15V, L19T, K20I, E35DN, M36I, R41K, Q61H, L63P, H69K, A71V, T74S, I85V, L89I, T91S, I93L	C
	12-3082	3082-30430	DQ877155	PI	NA	M46I, I84V, L90M	G73S	L10I, T12S, I13N, I15V, L19I, M36I, R41RK, Q61H, L63P, H69K, A71V, I72L, I93L	C
	48-1229	1229-30428	DQ877762	PI	NA	M46I, I54A, V82F, L90M		L10I, T12S, I13V, Q18R, L19I, K20I, E34EQ, E35E_PSDGNS, M36L, I62V, L63P, H69K, T74A, V77I, L89M, I93L	C
	48-1407	1407-30410	DQ877803	PI	NA	I54V, V82A, L90M	L10FI, K43T	T12PS, I15V, L19IK, K20I, E35D, M36I, R41K, D60E, Q61E, I62IV, L63P, H69K, A71V, I85V, I93L	C
	48-2254	2254-30930	DQ877888	PI	NA	G48V, I54V, V82S, L90M	L33F, Q58E	L10V, I13IV, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57RK, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95F, T96TS	C
	48-2405	2405-30826	DQ877890	PI	NA	M46I, V82A	L10F, K43T, T74P	T12S, I15V, L19T, K20R, M36I, Q61E, I62V, L63P, H69K, L89M, I93L	C
	48-3058	3058-30401	DQ877970	PI	NA	I54L, V82A, L90M	L33F, K43KT	L10I, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63P, H69K, T74S, L89M, I93L	C
	48-5096	5096-30901	DQ878592	PI	NA	M46I, I54V, V82A, L90M	K43KT, T74P	L10V, I13A, K20IM, E21K, A22V, M36I, R41RK, K55R, Q61N, L63P, I64V, H69K, L89M, I93L	C
	48-7101	7101-30723	DQ878954	PI	NA	M46I, I54V, V82A	L10F, L24I	T12P, I13V, L19I, K20I, E35D, M36I, R41K, L63P, H69K, T74AS, L89M, I93L	C
	48-9302	9302-30918	DQ877587	PI	NA	I54V, V82A, L90M	L10F, G73GS, L89IMV	I15V, K20I, E35D, M36I, N37K, R41N, Q61H, L63P, H69K, A71V, I85V, I93L	C
	48-8032	8032-30707	DQ879070	PI	NA	L90LM		T12S, I15V, L19I, M36I, R41K, L63P, H69K, K70KR, V82I, I93L	C
	48-8056	8056-30930	DQ879080	PI	NA	V32I, I47A	L33F, Q58E	L10I, T12S, I15V, L19I, K20T, M36I, D60E, L63P, H69K, T74A, V82I, I85V, L89M, I93L	C
Doualla-Bell (2006)	Pt10	FDB_Pt10		NFV		D30N, L90M	L33F	I15V, G17D, L19V, E35D, M36I, N37K, R41K, L63P, H69K, A71V, I93L	C
	Pt12	FDB_Pt12		NFV		N88S		T12S, I15V, L19I, M36I, R41K, L63P, I64L, H69K, I93L	C
	Pt13	FDB_Pt13		NFV		D30N, M46I	L10F, N88D	I15V, M36I, R41K, L63P, H69K, I93L	C
	Pt3	FDB_Pt3		NFV		D30N		T12S, I15V, L19V, K20T, E35D, M36I, R41K, K45Q, D60E, Q61E, L63P, H69K, V75I, I93L	C
	Pt9	FDB_Pt9		NFV		D30N	L33F, N88D	T12S, I15V, L19I, M36I, R41K, I62V, L63P, H69K, T74A, L89IM, I93L	C
Sanabani (2006)	04BR013	04BR013	AY727522	PI	NA	M46I, G48V, V82A	L24I	L10I, K20R, M36I, N37E, R41K, K55R, I62V, L63P, H69K, T74A, L89M, I93L	C
	04BR073	04BR073	AY727525	PI	NA			T12S, I13V, I15V, L19I, M36I, N37K, R41N, L63P, I64M, H69K, L89M, I93L	C
McGrath (2007)	6	DMG_6a		ATV	48			T12S, I15V, L19I, M36IT, R41K, K43KR, L63P, H69K, L89LM, I93L	C
Sen (2007)	T093	NPT93	EF186929	RTV, IDV		M46I, I54L, L90M	L23LI, G73ST	L10Y, T12S, L19T, K20I, L24LF, R41K, K45KR, K55KR, L63P, H69K, A71V, I72IM, V77I, I93L	C
		NPT93-PL	EF186978	RTV, IDV		M46I, I54IL, L90M	G73ST	L10Y, T12S, L19T, K20I, L24F, R41K, K45R, K55R, L63P, H69K, A71V, V77I, I93L	C
	T076	NPT76	EF186928	NFV, RTV		M46L, V82A, L90M	T74P	L10V, T12A, I15V, L19I, K20R, M36I, N37D, K55N, L63P, H69K, A71V, I93L	C
		NPT76-PL	EF186980	NFV, RTV		M46L	T74P	L10I, T12S, L19I, K20R, M36I, K55N, L63P, H69K, A71V, L89M, I93L	C
	T002	NPT2	EF186926	RTV, IDV		M46I, I54V, V82VA	L24I	L10I, T12S, I15V, L19I, M36L, N37S, R41K, Q61H, L63P, H69K, L89M, I93L	C
		NPT2-PL	EF186983	RTV, IDV		M46I, I54V, V82A	L24I	L10I, T12S, I15V, L19I, M36L, N37S, R41K, Q61H, L63P, H69K, A71AV, L89M, I93L	C
von Wyl (2007)	73	5326978	EF449871	PI	NA			T12S, I15V, G16E, L19Q, M36I, R41K, L63P, H69K, V82I, I93L	C
	74	3030600	EF449877	RTV, PI	NA			T12S, I13IM, L19I, M36I, N37K, R41N, G49GR, L63P, H69K, I93L	C
	41	662849	EF449918	PI	NA	D30N	N88D	I15V, E35D, M36I, N37K, R41HN, L63P, H69K, A71AV, I85IV, I93L	C
Marconi (2008)	SW070	SW070	EU308081	LPV	49	I54V, V82A	L33LF	G16A, L19V, E35D, M36I, R41K, I62V, L63P, H69K, T74S, L89M, I93L	C
	SW083	sw083	EU308093	LPV	91	V82A		T12S, I15V, L19I, K20R, M36I, R41K, L63P, H69K, L89M, I93L	C
	SW090	SW090	EU308099	LPV				T12S, I15V, L19T, E35D, M36I, R41K, K45R, D60E, I62V, L63P, H69K, V82I, L89M, I93L	C
Pillay (2008)	DR5	DR5	AY589870	SQV				T12S, I15V, L19I, M36I, R41K, L63P, H69K, T74S, I93L	C
	DR32	DR32	AY589889	LPV				T12S, I15V, Q18E, L19I, K20R, M36I, R41K, L63P, H69K, V77I, L89M, I93L	C
	DR37	DR37	AY589894	NFV		M46I, N88S, L90M	L10F	T12S, I13V, I15V, L19I, K20T, M36I, R41K, L63P, H69K, L89I, I93L	C
	DR51	DR51	AY589904	IDV	78	V82T	L10F	T12S, I15V, L19T, M36L, N37S, K45R, L63P, H69K, L89M, I93L, C95F	C
	DR60	DR60	AY589912	RTV		M46I, N88S		T12S, I15V, L19I, K20I, E35D, M36I, N37D, R41RK, D60E, L63P, H69K, A71AT, I72L, I93L	C
	DR68	DR68	AY589917	RTV	104	M46I, I54V, V82A		L10V, T12S, I15V, L19I, E35ED, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L	C
	DR23	02ZA.DR23	AY589882	IDV, LPV				T12S, I15V, G16A, G17D, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L	C
	DR81	03ZA.DR81	AY589925	NFV				T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
	DR92	03ZA.DR92	AY589931	IDV, LPV		V82A, L90M		T12S, I13IV, I15V, L19IT, K20R, M36I, L38LV, R41K, D60E, Q61E, I62IV, L63P, H69K, L89M, I93L	C
Riddler (2008)	64042	12728Ja		LPV	44			T12A, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L	C
Kandathil (2009)	VL06_253	VL06_253	EU030406	PI	NA	D30N	N88D, L89V	L10M, T12S, I13V, I15V, L19T, K20T, E21D, E35K, M36I, P39A, R41K, K45R, Q61D, L63P, H69K, T74S, V82I, I93L	C
	VL07_040	VL07_040	EU030407	PI	NA	M46I, L90M	K43T	T12S, I15V, L19I, K20T, E35D, M36I, R41K, L63P, H69K, T74S, I93L	C
	VL06_161	VL06_161	EU037773	PI	NA			T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L	C
	VL07_033	VL07_033	EU037776	PI	NA			T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L	C
	VL07_048	VL07_048	EU037778	PI	NA			T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
	VL07_063	VL07_063	EU037779	PI	NA			T12X, K14R, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
	VL07_103	VL07_103	EU781835	PI	NA	M46I, I54V, V82A	L24I	L10I, T12S, I15V, L19T, M36I, R41K, L63P, H69K, L89M, I93L	C
	VL07_097	VL07_097	EU781836	PI	NA			T12S, I15V, L19I, M36T, N37S, R41K, L63P, H69K, L89LM, I93L	C
	VL07_337	VL07_337	EU781838	PI	NA			L19T, K20R, M36V, R41K, L63P, H69K, L89M, I93L	C
	VL07_329	VL07_329	EU781839	PI	NA			K14R, I15V, L19M, M36I, R41K, L63P, H69K, L89M, I93L	C
	VL07_286	VL07_286	EU781840	PI	NA			T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L	C
	VL08_104	VL08_104	EU781841	PI	NA			I15V, L19T, M36V, R41K, D60E, Q61E, L63P, H69K, L89M, I93L	C
	VL08_071	VL08_071	EU781844	PI	NA			T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89LM, I93L	C
	VL08_145	VL08_145	EU781845	PI	NA			T12S, I15V, L19T, M36I, R41K, L63P, H69K, I93L	C
	VL08_097	VL08_097	EU781846	PI	NA			T12S, I15V, L19I, M36I, R41K, R57X, L63P, H69K, I93L	C
Kassaye (2009)	TCDD-05	TC05_2003	FJ445702	SQV	147	L90M		W6W*, P9PR, T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, A71V, I93L	C
	TCDD-28	TC28_2003	FJ445707	SQV	361	L90M	G73S	I15V, L19I, K20I, M36I, L63P, H69K, A71V, I93L	C
		TC28_2004	FJ445727	SQV, LPV	378	M46I, I84V, L90M	G73S	I15V, L19I, K20I, M36I, L63P, H69K, A71V, I93L	C
	TCDD-30	TC30_2003	FJ445708	NFV, IDV	99	I54V, I84V		L10I, T12A, I15V, L19I, K20KR, E35D, M36I, R41K, L63P, H69Q, L89M, I93L	C
	TCDD-35	TC35_2003	FJ445701	NFV, IDV	143			T12S, I15V, L19I, K20I, M36I, R41K, D60E, Q61E, L63P, H69K, I93L	C
		TC35_2004	FJ445721	NFV, IDV	143		I54IF	T12S, I13IL, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, I93L	C
	TCDD-23	TC23_2003	FJ445712	SQV	304	L90M		I15V, L19I, K20M, M36I, R41K, D60E, L63P, H69Q, V82I, L89M, I93L	C
	TCDD-31	TC31_2003	FJ445704	SQV, APV, IDV, LPV	198	M46MI, L76V	V32VG, I47IM	R41R*K, D60DE, L63P, H69K, T74A, I85V, L89M, I93L	C
	TC-52	TC52_2004	FJ445728	IDV	48			T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
	TC53	TC53_2003	FJ445735	NFV	8			M36I, R41K, D60E, L63P, H69K, L89M, I93L	C
Dau (2010)	05574B	05574B	GU581672	PI	NA			T12S, I15V, L19T, M36I, R41K, L63P, H69K, I93L	C
	07344A	07344A	GU581841	PI	NA	L90M		T12S, I13V, I15V, L19I, K20T, M36I, N37ND, R41K, L63P, H69K, V82I, L89M, I93L	C
	09218A	09218A	GU581962	PI	NA			T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
El-Khatib (2010)	Pat087	11ZA_SAVE1412	JF960537	LPV				T12S, I15V, L19T, M36I, R41K, L63P, H69K, L89M, I93L	C
	Pat095	11ZA_SAVE2018	JF960545	LPV				T12S, I15V, L19I, N37K, R41N, L63P, H69K, T74A, L89M, I93L	C
	Pat096	11ZA_SAVE2019	JF960546	LPV				T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89IM, I93IL	C
	Pat097	11ZA_SAVE2028	JF960547	LPV				T12S, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
	Pat098	11ZA_SAVE2040	JF960548	LPV				T12S, I15V, L19I, E35D, M36I, R41K, R57RK, D60E, Q61E, L63P, H69K, L89M, I93L	C
	Pat099	11ZA_SAVE2062	JF960549	LPV				T12S, L19I, M36I, R41K, K43R, L63P, H69K, L89M, I93L	C
	Pat102	11ZA_SAVE2082	JF960552	LPV				T12S, I15V, L19T, M36I, N37S, R41K, Q61E, L63P, H69K, I93L	C
	Pat104	11ZA_SAVE2119	JF960554	LPV				I15V, L19I, K20R, E35D, N37A, P39T, R41K, D60E, L63P, H69K, V77I, L89M	C
	Pat105	11ZA_SAVE2126	JF960555	LPV			Q58E	T12S, I15V, L19I, M36I, R41K, D60E, L63P, H69K, L89M, I93L	C
	Pat113	11ZA_SAVE2319	JF960563	LPV				T12S, I15V, L19I, K20R, M36I, R41K, D60E, Q61E, L63P, H69K, V77I, L89M, I93L	C
	Pat115	11ZA_SAVE2347	JF960565	LPV				T12S, I15V, L19I, N37S, R41K, L63P, H69K, V77I, V82I, I93L	C
	Pat117	11ZA_SAVE2359	JF960567	LPV				T12S, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L	C
	Pat125	11ZA_SAVE2442	JF960575	LPV				T12S, I15V, L19IV, M36I, R41K, L63P, H69K, I93L	C
	Pat126	11ZA_SAVE2455	JF960576	LPV				T12S, I15V, L19M, K20R, M36I, R41K, L63P, H69K, V77I, L89LM, I93L	C
	Pat129	11ZA_SAVE2478	JF960579	LPV				T12A, I15V, L19I, K20KR, E35D, M36I, R41RK, D60E, Q61E, L63P, H69K, L89M, I93L	C
Knops (2010)	ID2137	ID2137-GT1	GU271172	IDV, LPV		V32I, I47A, V82A		L10I, T12S, I15V, L19AP, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93L	C
		ID2137-GT2	GU271173	IDV, LPV, DRV, RTV	33	V32I, I54L, L76V, V82A	L89V	L5F, L10I, T12S, I15V, L19T, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93L	C
Rodrigues (2010)	34_08	BR08SC034	GQ401298	LPV				K14R, I15V, N37K, R41N, L63P, H69K, I93L	C
	36_08	BR08SC036	GQ401299	LPV				I15V, N37K, R41N, L63P, H69K, I93L	C
	315_07	BR07SC315	GQ401300	LPV				K14R, I15V, N37K, R41N, L63P, H69K, I93L	C
	317_07	BR07SC317	GQ401301	LPV				T12S, I15V, L19T, M36I, N37K, R41N, L63P, H69K, I93L	C
	318_07	BR07SC318	GQ401302	LPV				I15V, N37K, R41I, L63P, H69K, T74A, L89M, I93L	C
	326_07	BR07SC326	GQ401321	LPV				I15V, Q18L, M36L, N37K, R41N, L63P, H69K, L89M, I93L	C
Wallis (2010)	ZAP1	ZAP1	HM601455	LPV				T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L	C
Green (2011)	707PKE12F	707PKE12F	HM623503	LPV	81			T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L	C
	707PKE19F	707PKE19F	HM623509	RTV, LPV	131	M46I, I54V, L76V, V82A	Q58E	L10I, T12S, I15V, L19T, K20R, E35D, M36I, R41K, I62V, L63P, H69K, L89M, I93L	C
	707PKE33F	707PKE33F	HM623520	LPV				T12S, I15V, L19V, E35D, M36I, R41K, L63P, H69K, I93L	C
	707PKE49F	707PKE49F	HM623531	LPV	121			T12S, I15V, L19I, K20MR, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, I93L	C
Barber (2012)	47235	47235	JQ361673	LPV		L76V		T12S, I15V, L19I, M36I, R41K, L63P, H69K, L89M, I93L	C
	65994	65994	JQ361682	LPV		M46MI, I54V, V82A		L10I, T12S, I15V, L19V, M36I, R41K, K45KR, L63P, H69K, T74S, I93L	C
	56572	56572	JQ361684	LPV		V82A	L10F	I15V, G17D, L19I, M36I, D60E, L63P, H69K, L89M, I93L	C

Protease Inhibitors

Database

Resources

Team