<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63I
Rx >= 1 PI
IncludeMixtures No
References 9
Patients 16
Isolates 17
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Kantor (2002)TCDD-01TCDD-01AY090840NFV22  T12S, I15V, L19I, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63I, E65D, H69K, V82I, L89M, I93LC
Rodrigues (2010)323_07BR07SC323GQ401320LPV   T12P, I15V, L19Q, E35D, M36I, N37K, R41N, L63I, H69K, L89M, I93LC
Van Zyl (2013)192408.ZA.GT524KC423767LPV   T12S, I15V, L19I, K20R, M36I, R41K, I62V, L63I, H69K, K70KR, L89M, I93LC
Grossman (2014)169169KF134997SQV, RTV, LPV52  I15V, L19I, M36I, R41K, L63I, H69K, V82VI, L89M, I93LC
 11651165KF134957LPV52  T12S, I15V, L19IV, M36I, R41K, L63I, H69K, L89M, I93LC
  1165KF134958LPV92  Q7QE, T12S, I15V, L19IV, M36I, R41K, L63I, H69K, L89M, I93LC
 201201KF135014IDV, LPV52M46IT74PL10I, T12S, I15V, L19T, M36I, R41K, K55R, L63I, H69K, L89M, I93LC
Diaz (2015)RenG14577RenG14577KT745605PINA  I15V, M36T, N37K, R41I, L63I, H69K, T74S, L89I, I93LC
 RenG15054RenG15054KT746082PINA  I15V, L19LI, K20R, E35D, M36I, R41K, R57K, Q61N, L63I, H69K, T74S, P79S, L89M, I93LC
 RenG12407RenG12407KT743435PINA  L10I, I13V, K20R, M36I, N37E, R41N, Q61K, L63I, H69K, T74K, L89M, I93LC
 RenG10378RenG10378KT741406PINA  L10I, I15V, M36I, N37K, R41N, L63I, H69K, L89M, I93LC
Novitsky (2015)bcpp_298bcpp_298KR860724PINA  T12S, I15V, L19I, N37S, R41K, K43R, L63I, H69K, L89M, I93LC
Sutherland (2015)1616_POSTKT351814LPV   T12S, I15V, L19I, M36I, R41K, D60E, Q61E, L63I, H69K, L89F, I93L, N98NDC
Neogi (2016)86913.ZA.WC351KT593537LPV M46I, I50V, I54V, L90ML33II13V, I15IV, L19I, K20T, E35N, M36I, R41K, R57RK, Q61DN, L63I, I64V, H69K, T74A, V77I, V82I, L89M, I93LC
Posada Cespedes (2017)171212.ZA.GT2395KX542220LPV   T12S, I15V, L19I, M36I, R41K, L63I, H69K, L89M, I93LC
 96214.ZA.WC392KX544665LPV   T12S, I15V, L19I, E35D, M36I, N37S, R41K, K45R, L63I, H69K, T74S, L89M, I93LC
 427114.ZA.GT3549 LPV   I15V, K20R, E35D, M36I, N37D, R41K, L63I, H69K, T74S, I93LC