<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63H
Rx >= 1 PI
IncludeMixtures No
References 3
Patients 17
Isolates 17
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK186bUK186bAY900763SQV, RTV183I84V, L90MV11VI, G73GSL10I, I15V, G16E, L19I, R41K, L63H, H69K, A71V, V77I, I93LC
 UK598UK598AY900779IDV97L90M T12S, I15V, G16E, L19I, M36I, R41K, K45R, L63H, H69K, L89I, I93LC
 PL5249699430 IDV191  T12S, I15V, L19I, E35D, M36I, R41K, D60E, L63H, H69K, L89M, I93LC
Van Zyl (2013)15672032KC423577LPV26M46L, I54V, L76V, V82AL10FI15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61N, L63H, H69K, L89I, I93LC
 14602908KC423889LPV26M46I, I54V, V82AL10F, L24LI, L33F, T74PI13V, G16E, L19T, K20M, E35D, M36I, R41K, Q61N, L63H, H69K, I72IV, L89M, I93LC
 61843KC424312LPV26  T12S, I15V, G16E, L19I, N37S, L63H, H69K, V77I, I93ILC
 7511563KC423234LPV26M46I, I50V, I54V, V82AL23IL10I, T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61HN, L63H, H69K, A71V, I72IM, L89M, I93LC
 15442438KC423708LPV26 V11IT12S, I15V, G16E, L19I, R41K, K55R, D60E, L63H, H69K, V77I, L89I, I93LC
 15292746KC423811LPV26  L5X, T12S, I15V, L19I, M36I, N37D, L63H, H69K, L89I, I93LC
 1279633KC424191LPV26  T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, Q61QHKN, L63H, H69K, L89M, I93LC
 16322976KC423913LPV26  T12A, I13V, I15V, G16E, L19I, K20R, M36I, R41K, L63H, H69K, K70R, L89M, I93LC
Steegen (2014)11ZAKS08611ZAKS086KJ176368LPV   R41K, L63H, H69K, L89M, I93LC
 09ZAKS00209ZAKS002KJ176286LPV   R41K, L63H, H69K, L89M, I93LC
 10ZAKS06910ZAKS069KJ176351LPV   R41K, I62V, L63H, H69K, A71T, I93LC
 10ZAKS04310ZAKS043KJ176325LPV   R41K, L63H, H69K, L89M, I93LC
 12ZAKS26712ZAKS267KJ176546LPV   R41N, I62V, L63H, H69K, I72IV, V82I, L89I, I93LC
 12ZAKS34812ZAKS348KJ176627LPV M46L R41K, L63H, H69K, L89M, I93LC