<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63C
Rx PI-naive
IncludeMixtures No
References 16
Patients 42
Isolates 43
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK740UK740AY900782None   T12S, L19I, M36I, P39Q, R41K, I62V, L63C, H69K, A71T, I72V, I93LC
Kassu (2007)ETH-G-068G-068AB285779None   L10V, I15V, G16E, K20KR, M36I, N37T, P39S, L63C, H69K, L89MC
Martinson (2007)KEH161BKEH161BEU152443None   T12S, I15V, L19T, K20R, E35D, M36I, R41K, L63C, H69K, T74S, L89M, I93LC
 KEH161MKEH161MEU152444None   T12S, I15V, L19T, K20R, E35D, M36I, R41K, L63C, H69K, T74S, V82VI, L89M, I93LC
Wallis (2009)22816722281672 None   L10LI, I13V, L19V, M36I, R41K, L63C, I64M, H69K, L89M, I93LC
 TJC2393652TJC2393652 None   L10LI, I13IV, L19IV, M36I, R41K, R57RK, L63C, I64M, H69K, L89M, I93LC
 TJC2413549TJC2413549 None   T12S, I15V, L19I, M36I, N37D, R41K, I62IV, L63C, H69K, A71T, I93LC
 23622102362210 None   I15V, G16E, L19I, E35D, M36I, N37D, D60E, L63C, H69K, L89M, I93LC
 TJC2388289TJC2388289 None   T12S, I15V, G16E, L19I, M36I, R41K, D60E, Q61E, L63C, H69K, L89IM, I93LC
Gonzalez (2010)LUC8LUC8GQ433849None   T12S, I15V, L19I, K20R, E35D, M36I, R41K, L63C, H69K, V82I, L89M, I93LC
Wright (2010)297SK297HM593300None   T12S, I15V, Q18E, L19I, K20R, E35D, M36I, R41K, L63C, H69K, L89M, I93LC
 387SK387HM593393None   L10LI, I15IV, L19AITV, M36I, R41K, D60E, I62IV, L63C, E65ED, H69K, L89LM, I93LC
Hamers (2011)300104CP076300104HM119682None   T12S, I15V, G17D, L19I, K20R, E35D, M36I, R41K, L63C, H69K, T74S, L89M, I93LC
 300132CP076300132HM119708None   K14R, I15V, L19I, M36I, R41K, R57RK, L63C, H69K, I93LC
 300632CP076300632HM120029None   T12S, I15V, L19I, E35D, M36I, R41K, L63C, H69K, T74A, L89MC
 CP076300310CP076300310HQ994358None   L10V, T12S, L19I, R41K, L63C, H69K, T74S, V77I, L89MC
 CP076300993CP076300993HQ994562None   T12S, I15V, G16A, L19I, M36I, R41K, D60E, Q61E, L63C, H69K, L89M, I93LC
 CP076301066CP076301066HQ994590None   I15V, E35D, M36I, R41K, I62IV, L63C, H69K, T74SC
 CP763A03401CP763A03401HQ994659None   K14KN, I15IV, G16GE, L19I, M36I, L63C, H69K, L89M, I93LC
Nwobegahay (2011)08MB09ZA08MB09ZAGU188812None   T12S, I15V, L19I, K20R, E35D, M36I, R41K, L63C, H69K, T74S, L89M, I93LC
van Zyl (2011)A183A183JN638108None   K14R, I15V, L19I, E35D, M36I, R41K, L63C, H69K, I93LC
Wright (2011)AS2-1325B2AS2-1325B2HQ696817None   T12S, I15V, G16E, L19I, M36I, R41K, L63C, H69K, L89M, I93LC
De Gascun (2012)IRL26145IRL26145JN622955None   T12S, I15V, L19I, M36I, R41K, L63C, H69Q, L89M, I93LC
 IRL55706IRL55706JN623024None   T12S, K14I, I15V, G16E, L19IV, E35D, M36I, R41K, K45R, D60E, L63C, H69K, L89M, I93LC
 IRL62145IRL62145JN623030None   T12S, K14I, I15V, G16E, L19I, E35D, M36I, R41RK, D60E, L63C, H69K, L89M, I93LC
Hunt (2012)GP09_0041GP09_0041KF736711None   T12S, I15V, G16E, L19I, E35D, M36I, R41K, R57K, L63C, H69K, T74S, I93LC
Nwobegahay (2012)BBCR38ZABBCR38ZAGU177484None   T12S, I15K, L19I, K20R, M36I, N37D, R41K, L63C, H69K, I93LC
Bila (2013)MZ10-138HIV-1KF927247None   I15V, L19I, E35D, M36I, R41K, R57K, L63C, H69K, A71T, I93LC
 MZ09-083HIV-1KF927221None   T12S, I15V, L19I, E35D, M36I, R41K, D60E, L63C, H69K, L89M, I93LC
 MZ10-208HIV-1KF927307None   I15V, G16E, K20R, E35D, M36I, R41K, R57RK, Q61QE, L63C, H69K, I93LC
 MZ10-191HIV-1KF927291None   T12S, L19I, K20R, M36I, N37S, R41K, L63C, H69K, L89M, I93LC
 MZ10-199HIV-1KF927299None   T12A, L19I, M36I, R41K, L63C, H69K, I93LC
Masimba (2013)TZ.HLM.020TZ.HLM.020KC537242None   T12S, I15V, L19I, M36I, R41K, L63C, I64L, H69K, L89MC
Van Zyl (2013)1296807KC424286None   K14N, I15V, G16E, L19I, K20R, M36I, N37NS, R41K, Q61E, L63C, H69K, L89M, I93LC
 15012074KC423598None   I15V, G16E, L19I, R41K, D60E, Q61K, L63C, I64L, H69K, I72M, L89M, I93LC
 9951296KC423038None   T12S, I15V, G16E, L19I, R41K, Q61E, L63C, H69K, V77I, I93LC
 1129247KC423726None   T12S, I15V, G16E, L19I, M36I, R41K, D60E, L63C, H69K, I72V, L89I, I93LC
 126317KC423982None   T12S, I15V, G16E, L19I, E35D, M36I, R41K, D60E, L63C, H69K, V77I, L89M, I93LC
  291KC423890None   T12S, I15V, G16E, L19I, E35D, M36I, R41K, D60E, L63C, H69K, V77I, L89M, I93LC
 7371010KC422802None   T12S, I15V, G16E, L19I, M36L, R41K, L63C, H69K, V82I, L89M, I93LC
 13801672KC423314None   T12S, I15V, L19V, K20R, E35D, M36I, R41K, L63C, H69K, T74S, L89M, I93LC
 786287KC423865None   T12S, I15V, G16E, L19I, K20R, M36I, P39S, D60E, Q61E, L63C, H69K, V82I, L89M, I93LC
 9961374KC423102None   T12S, I15V, G16E, L19I, R41K, Q61E, L63C, H69K, V77I, I93LC