<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63C
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 16
Isolates 18
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Baxter (2006)48-41344134-30317DQ878365PINAG48V, I54V, V82A, I84VL33F, K43TL10I, I15V, G16E, L19I, K20V, E35DN, M36I, L63C, H69K, T74S, I85V, L89M, I93LC
Waleria-Aleixo (2008)08RJ0407608RJ04076FJ591560PINAL90M T12P, K14R, I15V, K20T, E35D, M36I, N37K, R41N, L63C, H69K, A71I, T74S, I93LC
 08PR04018608PR040186FJ591217PINA  T12S, K14R, I15V, G16E, N37KR, R41N, L63C, H69K, V82VI, I93LC
Van Zyl (2013)365309.ZA.GT904KC424416LPV   T12S, G16E, L19IM, E35D, N37NH, L63C, H69K, V77I, L89M, I93LC
 353108.ZA.GT537KC423830LPV   I15V, G16E, K20R, M36I, P39S, R41K, D60E, L63C, H69K, L89M, I93LC
  09.ZA.GT770KC424285LPV V82VAL10LFI15V, G16E, K20R, M36I, P39S, R41K, D60E, L63C, H69K, L89LM, I93LC
Grossman (2014)166166KF134995LPV52  T12S, I15V, G16E, L19I, M36I, R41K, Q61N, L63C, H69K, V82I, I93LC
 17271727KF134999LPV52  I15V, G16E, E35D, M36I, R41K, L63C, H69K, I93LC
 11121112KF134950LPV52  I15V, G17D, K20R, M36I, R41K, L63C, H69K, L89M, I93LC
 55KF135110RTV, LPV52M46L, I54V, V82AL24L*IR, N88NDL10V, I15V, K20R, E35D, M36I, R41K, Q61N, L63C, H69K, T74A, L89MC
  5KF135111RTV, LPV265I54V, V82A L10IV, I15IV, G16GE, K20R, E35D, M36I, R41K, Q61N, L63C, H69K, T74A, L89MC
 751751 LPV52  G17E, K20R, M36I, R41K, L63C, H69K, L89LM, I93LC
Diaz (2015)RenG13907RenG13907KT744935PINA  K14R, I15V, K20R, M36I, N37K, R41N, L63C, H69K, L89M, I93LC
 RenG12731RenG12731KT743759PINA  I15V, K20T, E35D, M36I, N37NK, R41N, K45R, L63C, H69K, A71V, T74TS, L89T, I93LC
 RenG10768RenG10768KT741796PINA  K14R, I15V, G16E, M36I, N37K, R41N, L63C, H69K, I93LC
Rossouw (2015)RP126RP126KT032045RTV, LPV348M46I, I54V, L76V, V82L Q7E, K14R, I15V, G16E, L19I, K20T, E35D, M36I, Q61N, L63C, H69K, L89I, I93LC
Neogi (2016)68513.ZA.EC867KT592942LPV  Q58ET12S, I15V, L19T, K20R, E35D, M36I, R41K, R57K, D60E, L63C, H69K, L89MC
 322113.ZA.GT2672KT593043LPV   T12S, I15V, L19T, M36I, R41K, D60E, Q61E, L63C, H69K, L89LM, I93LC