<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63C
Rx >= 1 PI
IncludeMixtures No
References 3
Patients 7
Isolates 9
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Baxter (2006)48-41344134-30317DQ878365PINAG48V, I54V, V82A, I84VL33F, K43TL10I, I15V, G16E, L19I, K20V, E35DN, M36I, L63C, H69K, T74S, I85V, L89M, I93LC
Van Zyl (2013)1209279KC423830LPV26  I15V, G16E, K20R, M36I, P39S, R41K, D60E, L63C, H69K, L89M, I93LC
  800KC424285LPV78V82VAL10LFI15V, G16E, K20R, M36I, P39S, R41K, D60E, L63C, H69K, L89LM, I93LC
 1305985KC424416LPV26  T12S, G16E, L19IM, E35D, N37NH, L63C, H69K, V77I, L89M, I93LC
Grossman (2014)166166KF134995LPV52  T12S, I15V, G16E, L19I, M36I, R41K, Q61N, L63C, H69K, V82I, I93LC
 17271727KF134999LPV52  I15V, G16E, E35D, M36I, R41K, L63C, H69K, I93LC
 11121112KF134950LPV52  I15V, G17D, K20R, M36I, R41K, L63C, H69K, L89M, I93LC
 55KF135110RTV, LPV52M46L, I54V, V82AL24L*IR, N88NDL10V, I15V, K20R, E35D, M36I, R41K, Q61N, L63C, H69K, T74A, L89MC
  5KF135111RTV, LPV265I54V, V82A L10IV, I15IV, G16GE, K20R, E35D, M36I, R41K, Q61N, L63C, H69K, T74A, L89MC