<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L63A
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 23
Isolates 28
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M6M6AY010422SQV   T12S, I15V, G16E, L19Q, M36I, N37R, R41N, Q61N, L63A, H69K, V82I, L89M, I93LC
 NY_M62M62AY010425SQV   T12S, I15V, G16E, L19Q, M36I, N37R, R41N, Q61N, L63A, H69K, V82I, L89M, I93LC
Kantor (2002)TCDD-22TCDD-22AY090849SQV, IDV17  I15V, L19I, M36I, R41K, L63A, H69K, I93LC
Grossman (2004)IL369IL369AY529591NFV111M46I, L90M T12S, I13V, L19I, R41K, K45Q, L63A, H69K, T74K, V77I, I85IV, L89M, I93LC
Montes (2004)MB_patNIB01_NIB710AJ577964NFV94  T12S, I13V, I15V, L19I, M36I, N37K, R41N, Q61E, L63A, I64M, H69K, L89M, I93LC
  01_NIB719AJ577965NFV94L90ML23IT12S, I13V, I15V, L19I, K20T, E35D, M36I, N37R, R41N, Q61E, L63A, I64M, H69K, V82I, L89M, I93LC
Weber (2005)F26249F26249AY677450NFV103 L89MVT12S, L19I, K20KR, M36I, R41K, L63A, H69K, I93LC
 M69708M69708AY677400NFV81  T12S, L19I, K20R, M36I, N37D, R41K, L63A, I64V, H69K, I93LC
Pillay (2008)DR71DR71AY589920RTV43V32VI, V82AM46MVI15IV, G16E, L19I, M36I, R41K, Q61H, L63A, E65D, H69K, I72V, L89M, I93LC
 DR1402ZA.DR14AY589876IDV   T12S, I15V, L19I, M36I, R41K, L63A, H69K, I93LC
Barber (2012)3324533245JQ361668LPV  Q58ET12S, L19I, M36I, R41K, D60E, L63A, H69K, L89M, I93LC
El Annaz (2012)25392539.PRJN185242IDV52V82A T12S, I15V, L19I, M36I, N37D, K45R, L63A, H69K, L89M, I93LC
Van Zyl (2013)76324KC423693LPV26  T12S, I15V, G16E, L19T, K20M, D29A, E35D, M36I, L63A, H69K, T74S, L89M, I93LC
 77149KC424090LPV26  T12S, I15V, L19T, M36I, N37S, R41K, L63A, H69K, L89M, I93LC
  433KC424058LPV78  T12S, I15V, L19T, M36I, N37S, R41K, L63A, H69K, L89M, I93LC
 52695KC423791LPV26  T12S, G16E, L19I, E35D, W42W*, L63A, H69K, V77I, L89M, I93LC
 16151058KC422843LPV26  T12S, I15V, G16E, L19I, K20R, M36I, R41K, L63A, H69K, V77I, L89M, I93LC
 14472175KC423669LPV26  T12S, L19T, K20R, M36I, L63A, H69K, L89M, I93LC
 15621774KC423396LPV26  T12S, I15V, L19I, E35D, M36I, R41K, R57RK, Y59F, Q61E, L63A, H69K, L89M, I93LC
 7051933KC423519LPV104  K14R, L19I, M36I, N37S, R41K, L63A, H69K, V82I, L89M, I93LC
 43773KC424251LPV26  T12S, I15V, L19I, M36I, R41K, L63A, H69K, I93LC
  310KC423970LPV78 L76LIT12S, I15V, L19I, M36I, R41K, R57RK, L63A, H69K, I93LC
  1192KC422953LPV182  T12S, I15V, L19I, M36I, R41K, L63A, H69K, I93LC
  1733KC423363LPV234  T12S, I15V, L19I, M36I, R41K, L63A, H69K, I93LC
 16851038KC422825LPV26  T12S, I15V, G16E, L19T, K20R, L63A, H69K, V77I, L89M, I93LC
 17231898KC423497LPV26 I84TT12S, G16E, L19I, M36I, R41K, D60E, L63A, H69K, L89M, I93LC
Grossman (2014)987987KF135176LPV52  T12S, I15V, L19IV, E35E_X, M36IT, R41K, R57RK, L63A, H69K, I93LC
 589589KF135105LPV52  L19I, M36I, R41K, D60E, I62V, L63A, H69K, I93LC