<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation I54A
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 7
Isolates 7
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Snoeck (2004)BE59BE59AY900757SQV, IDV, RTV, NFV217G48V, I54A, V82AL33F, K43KTL10I, I13V, I15V, L19I, M36L, N37EQ, L38M, I62V, L63V, H69K, I72V, T74S, L89LI, I93LC
Non-B Workgroup (2005)TK3035TK3035 IDV, NFV, RTV202I54A, V82A L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K45KR, D60E, L63P, H69K, A71V, L89M, I93LC
Baxter (2006)48-12291229-30428DQ877762PINAM46I, I54A, V82F, L90M L10I, T12S, I13V, Q18R, L19I, K20I, E34EQ, E35E_PSDGNS, M36L, I62V, L63P, H69K, T74A, V77I, L89M, I93LC
Saravanan (2013)YRG76YRG76KC016271PINAI54A, V82L, L90MQ58EL10I, I13IV, I15V, G16X, L19I, K20T, E35D, M36I, N37D, R57K, Q61N, L63T, H69K, A71V, L89M, I93LC
 YRG38YRG38KC016233PINAM46I, I54A, V82AK43TL10V, T12S, I15V, L19I, K20R, M36I, R41K, K55R, I62V, L63P, H69Q, L89M, I93LC
Acharya (2014)DGP025DGP025KJ185195RTV, ATV M46I, I54A, V82A, L90ML10FT12S, I15V, G16A, L19I, M36L, N37C, L63T, H69K, L89M, I93LC
Diaz (2015)RenG13840RenG13840KT744868PINAI54A, V82M, L90MQ58EL10I, I15V, G16A, K20R, E35D, M36I, R41K, I62IV, L63P, H69K, A71IV, I72IT, I85V, L89M, Q92QK, I93LC