<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation I50V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 11
Isolates 12
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK1447bUK1447bAY900833IDV, NFV, SQV, RTV, APV, LPV175M46I, I50V, I54V, V82A, L90ML10F, L23I, K43TI15V, K20R, E35D, M36I, R41K, I62V, L63V, H69K, A71V, T74S, L89I, I93LC
Kouri (2012)CU728-10CU728-10JQ585411PINAM46I, I50V, L90ML33FW6G, L10V, N37S, R41K, K55R, Q61E, L63P, H69K, T74S, V77I, V82VI, I85V, L89M, I93LC
Van Zyl (2013)751548KC424133LPV26M46I, I50V, I54V, V82AL23IL10I, T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61HN, L63N, H69K, A71V, L89M, I93LC
  1563KC423234LPV26M46I, I50V, I54V, V82AL23IL10I, T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61HN, L63H, H69K, A71V, I72IM, L89M, I93LC
 16441954KC423531LPV26M46I, I50V, I54V, V82A L10R, T12S, I15V, L19I, K20R, E35D, M36I, R41K, L63P, H69R, K70Q, A71V, I93LC
 13041121KC422895LPV26M46I, I50V T12S, I15V, L19I, K20R, E35D, M36I, R41K, L63S, H69K, I93LC
 16801795KC423414LPV26M46I, I50V, I54V, V82AL10F, L33FT12TS, I15IV, G16E, L19I, K20R, E35D, M36I, R41K, R57K, Q61H, L63S, H69K, A71V, L89M, I93LC
Grossman (2014)882882KF135160NFV, LPV52M46I, I50V, I54V, L90ML23II13V, K20T, L33V, E35D, M36I, R41RK, K55KNRS, I62IV, H69K, T74S, V82I, L89I, I93LC
 217217KF135025NFV, LPV273M46I, I50V, I54V, V82A, L90ML33FL10I, I13V, K14R, I15V, K20R, E35D, M36I, N37DE, R41K, K55R, L63E, G68GE, H69Q, A71AV, L89I, I93LC
Steegen (2014)11ZAKS17111ZAKS171KJ176452LPV M46I, I50V, I54V, V82A R41K, K55R, R57K, Q61H, L63T, H69K, A71V, I72K, T74S, L89M, I93LC
Rossouw (2015)RP038RP038KT032009LPV89M46MI, I50V, I54V, V82A L10I, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, Q61D, I66L, H69K, A71AV, L89M, I93LC
 RP104RP104KT032036LPV124M46I, I50V, I54V, V82A L10I, T12S, I15V, L19V, K20R, T31TI, E35D, M36I, R41K, L63P, H69K, K70R, A71V, V77I, L89M, I93LC