<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation I50V
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 16
Isolates 17
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK1447bUK1447bAY900833IDV, NFV, SQV, RTV, APV, LPV175M46I, I50V, I54V, V82A, L90ML10F, L23I, K43TI15V, K20R, E35D, M36I, R41K, I62V, L63V, H69K, A71V, T74S, L89I, I93LC
Kouri (2012)CU728-10CU728-10JQ585411PINAM46I, I50V, L90ML33FW6G, L10V, N37S, R41K, K55R, Q61E, L63P, H69K, T74S, V77I, V82VI, I85V, L89M, I93LC
Van Zyl (2013)77111.ZA.WC161KC423531LPV M46I, I50V, I54V, V82A L10R, T12S, I15V, L19I, K20R, E35D, M36I, R41K, L63P, H69R, K70Q, A71V, I93LC
 364910.ZA.GT1047KC422895LPV M46I, I50V T12S, I15V, L19I, K20R, E35D, M36I, R41K, L63S, H69K, I93LC
 86311.ZA.WC140KC423414LPV M46I, I50V, I54V, V82AL10F, L33FT12TS, I15IV, G16E, L19I, K20R, E35D, M36I, R41K, R57K, Q61H, L63S, H69K, A71V, L89M, I93LC
 296108.ZA.GT353KC424133LPV M46I, I50V, I54V, V82AL23IL10I, T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61HN, L63N, H69K, A71V, L89M, I93LC
  10.ZA.GT1445KC423234LPV M46I, I50V, I54V, V82AL23IL10I, T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61HN, L63H, H69K, A71V, I72IM, L89M, I93LC
Grossman (2014)882882KF135160NFV, LPV52M46I, I50V, I54V, L90ML23II13V, K20T, L33V, E35D, M36I, R41RK, K55KNRS, I62IV, H69K, T74S, V82I, L89I, I93LC
 217217KF135025NFV, LPV273M46I, I50V, I54V, V82A, L90ML33FL10I, I13V, K14R, I15V, K20R, E35D, M36I, N37DE, R41K, K55R, L63E, G68GE, H69Q, A71AV, L89I, I93LC
Steegen (2014)11ZAKS17111ZAKS171KJ176452LPV M46I, I50V, I54V, V82A R41K, K55R, R57K, Q61H, L63T, H69K, A71V, I72K, T74S, L89M, I93LC
Diaz (2015)RenG13551RenG13551KT744579PINAM46MI, I50V, I54V, V82M, N88SL33F, Q58E, T74PL10V, G16E, K20R, E35D, M36I, N37K, R41N, R57RK, L63T, H69K, L89F, I93LC
 RenG14113RenG14113KT745141PINAG48V, I50V, I54V, V82AL33IL10I, I13V, L19IV, E35D, M36I, N37R, R41N, Q61E, I62V, L63P, H69K, T74S, I85V, L89IC
 RenG12082RenG12082KT743110PINAM46I, I50V, V82A, L90ML10F, V11VI, L23I, L33F, Q58EI13V, I15V, K20R, E35D, M36I, N37K, R41N, L63P, H69K, G73V, T74S, L89T, I93LC
 RenG10982RenG10982KT742010PINAM46I, I50V, I54V, V82A, L90MV11I, L33F, K43T, T74PL10I, I13V, I15V, K20R, E35D, M36I, N37K, R41N, I62IV, L63P, H69R, A71V, L89LM, I93LC
Rossouw (2015)RP038RP038KT032009LPV89M46MI, I50V, I54V, V82A L10I, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, Q61D, I66L, H69K, A71AV, L89M, I93LC
 RP104RP104KT032036LPV124M46I, I50V, I54V, V82A L10I, T12S, I15V, L19V, K20R, T31TI, E35D, M36I, R41K, L63P, H69K, K70R, A71V, V77I, L89M, I93LC
Neogi (2016)86913.ZA.WC351KT593537LPV M46I, I50V, I54V, L90ML33II13V, I15IV, L19I, K20T, E35N, M36I, R41K, R57RK, Q61DN, L63I, I64V, H69K, T74A, V77I, V82I, L89M, I93LC