<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation I47A
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 10
Isolates 14
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Baxter (2006)48-80568056-30930DQ879080PINAV32I, I47AL33F, Q58EL10I, T12S, I15V, L19I, K20T, M36I, D60E, L63P, H69K, T74A, V82I, I85V, L89M, I93LC
Knops (2010)ID2137ID2137-GT1GU271172IDV, LPV V32I, I47A, V82A L10I, T12S, I15V, L19AP, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93LC
Van Zyl (2013)1288961KC424397LPV26I47AF53LT12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, L63P, H69K, A71V, I93LC
  1594KC423256LPV78I47AF53LT12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, D60E, L63P, H69K, A71V, I93LC
  1482KC423174LPV79I47A, N88NSF53LT12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, D60E, L63P, H69K, A71V, I93LC
 1009222KC423684LPV130V32I, I47A T12S, K14R, L19I, M36I, R41K, K45R, L63P, H69K, T74S, L89M, I93LC
  891KC424341LPV182V32I, I47A T12S, K14R, L19I, M36I, R41K, K45R, L63P, H69K, T74S, L89M, I93LC
  1082KC422868LPV184V32I, I47A T12S, K14R, L19I, M36I, R41K, K45R, L63P, H69K, T74S, L89M, I93LC
Grossman (2014)311311KF135048LPV148M46L, I47A T12S, I13IV, I15V, L19K, K20I, M36I, Q61E, L63T, H69K, T74S, L89I, I93LC
Steegen (2014)12ZAKS31912ZAKS319KJ176598LPV I47A, V82A R41K, R57K, L63P, H69Q, A71V, I93LC
 11ZAKS10611ZAKS106KJ176388LPV M46L, I47A, I84V R41K, L63P, H69Q, I72V, I93LC
 11ZAKS11711ZAKS117KJ176399LPV M46L, I47A, I84V R41K, K45R, L63P, H69Q, I72V, V82I, I93LC
 12ZAKS29112ZAKS291KJ176570LPV M46I, I47A, I54VK43TR41K, R57K, D60E, L63P, H69K, A71V, V82I, L89M, I93LC
 12ZAKS28212ZAKS282KJ176561LPV I47A, V82C R41K, L63T, H69K, I93LC