<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation M36V
Rx >= 1 PI
IncludeMixtures No
References 13
Patients 27
Isolates 27
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Grossman (2004)IL401IL401AY529596NFV209L90LM L10R, V11F, K14R, D29DV, E35D, M36V, N37ND, R41K, L63P, I64IV, H69K, I72IV, L89LM, I93LC
Non-B Workgroup (2005)TK2020TK2020 SQV, RTV250  T12S, I15V, L19V, M36V, R41K, L63P, I64L, H69K, L89M, I93LC
Rhee (2005)CA7907CA24813AY797580IDV, NFV260D30NL10F, N88DT12P, K14R, I15V, G16E, K20IT, E35G, M36V, R41K, L63T, H69Q, T74S, V77VI, I85IV, L89M, I93LC
Sen (2007)T009NPT9-PLEF186959SQV, RTV   T12S, K14R, I15V, G16E, L19I, M36V, R41K, Q61H, L63T, H69K, L89M, I93LC
Waleria-Aleixo (2008)08PR06070808PR060708FJ591531PINAD30NN88DI13V, G16A, K20R, E35D, M36V, N37Q, R41N, H69K, T74S, L89M, I93LC
 08PR06070208PR060702FJ591527PINAD30NN88DGG16E, K20R, E35D, M36V, N37K, R41N, Q61E, H69K, I72R, V82I, L89M, I93LC
Kandathil (2009)VL07_108VL07_108EU781837PINA  T12S, K14R, I15V, G16E, L19I, M36V, R41K, D60E, Q61E, L63T, H69K, I93LC
 VL07_337VL07_337EU781838PINA  L19T, K20R, M36V, R41K, L63P, H69K, L89M, I93LC
 VL08_104VL08_104EU781841PINA  I15V, L19T, M36V, R41K, D60E, Q61E, L63P, H69K, L89M, I93LC
Saravanan (2013)YRG87YRG87KC016282PINA L10FT12P, I15V, L19I, M36V, R41K, L63P, H69K, T91SC
 YRG79YRG79KC016274PINAM46I, I54V, V82F, L90MK43TL10I, L19I, E35D, M36V, I62V, L63P, H69K, I72IV, T74A, L89M, I93LC
 YRG66YRG66KC016261PINAL90LM T12S, I15V, G16A, L19I, E35ED, M36V, R41K, K45KR, L63P, H69K, I93LC
 YRG50YRG50KC016245PINAI54VM46VI3V, I15V, E35D, M36V, N37D, D60E, L63P, H69K, A71VC
 YRG33YRG33KC016228PINAL90M T12S, I15V, L19I, M36V, R41K, L63P, H69K, I93LC
Van Zyl (2013)377711.ZA.GT1759KC423545LPV   T12S, L19I, M36V, R41K, D60E, L63P, H69K, L89M, I93LC
 395712.ZA.GT2066KC423774LPV   T12S, I15V, L19I, E35D, M36V, R41K, L63V, H69K, T74S, L89M, I93LC
 185812.ZA.GT2201KC423875LPV   T12S, L19I, M36V, D60E, I62V, L63P, H69K, V82I, L89M, I93LC
Acharya (2014)DGP190DGP190KJ185360LPV I54V, V82A I15V, L19T, M36V, R41K, L63P, H69K, I85V, I93LC
 DGP178DGP178KJ185348LPV   T12S, K14R, I15V, G16E, L19I, M36V, R41K, Q61H, L63T, H69K, L89M, I93LC
 DGP177DGP177KJ185347RTV, ATV   T12A, I15V, L19I, L24F, M36V, R41K, L63P, H69K, L89M, I93LC
 DGP139DGP139KJ185309RTV, ATV   T12S, K14R, I15V, L19T, M36V, N37D, L63P, H69K, I93LC
 DGP121DGP121KJ185291LPV M46I, I54V, L76V, V82AL10FT12S, K14R, I15V, L19T, M36V, N37D, L63P, H69K, A71V, I93LC
Diaz (2015)RenG13590RenG13590KT744618PINA  T12S, K14R, I15V, L19T, E35E_T, M36V, N37E, K43R, H69K, L89M, I93LC
 RenG11086RenG11086KT742114PINAM46I, I47A, I84VF53LL10V, G16E, E35D, M36V, N37E, P39S, R41N, I62V, L63T, H69R, A71V, T74S, L89M, I93LC
Rossouw (2015)RP167RP167KT032058LPV, RTV312M46I, I54V, V82AL10F, L24I, K43TI15V, L19I, K20R, E35D, M36V, N37E, R57K, I62V, L63P, H69K, V77I, L89I, I93LC
Steegen (2016)ZA13GFNCC002ZA13GFNCC002KU252895LPV   T12S, L19I, M36V, R41K, K45R, L63A, H69K, I72IV, T74S, L89MC
Posada Cespedes (2017)327608.ZA.GT367KX539864LPV   Q7R, T12S, I15V, G16E, L19I, M36V, R41K, L63M, H69K, L89M, I93LC