<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation M36V
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 10
Isolates 10
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Grossman (2004)IL401IL401AY529596NFV209L90LM L10R, V11F, K14R, D29DV, E35D, M36V, N37ND, R41K, L63P, I64IV, H69K, I72IV, L89LM, I93LC
Non-B Workgroup (2005)TK2020TK2020 SQV, RTV250  T12S, I15V, L19V, M36V, R41K, L63P, I64L, H69K, L89M, I93LC
Rhee (2005)CA7907CA24813AY797580IDV, NFV260D30NL10F, N88DT12P, K14R, I15V, G16E, K20IT, E35G, M36V, R41K, L63T, H69Q, T74S, V77VI, I85IV, L89M, I93LC
Sen (2007)T009NPT9-PLEF186959SQV, RTV   T12S, K14R, I15V, G16E, L19I, M36V, R41K, Q61H, L63T, H69K, L89M, I93LC
Kandathil (2009)VL07_108VL07_108EU781837PINA  T12S, K14R, I15V, G16E, L19I, M36V, R41K, D60E, Q61E, L63T, H69K, I93LC
 VL07_337VL07_337EU781838PINA  L19T, K20R, M36V, R41K, L63P, H69K, L89M, I93LC
 VL08_104VL08_104EU781841PINA  I15V, L19T, M36V, R41K, D60E, Q61E, L63P, H69K, L89M, I93LC
Van Zyl (2013)13831989KC423545LPV26  T12S, L19I, M36V, R41K, D60E, L63P, H69K, L89M, I93LC
 14822669KC423774LPV26  T12S, I15V, L19I, E35D, M36V, R41K, L63V, H69K, T74S, L89M, I93LC
 3662886KC423875LPV104  T12S, L19I, M36V, D60E, I62V, L63P, H69K, V82I, L89M, I93LC