<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation M36T
Rx PI-naive
IncludeMixtures No
References 41
Patients 75
Isolates 75
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Handema (2002)H00ZM4781H00ZM4781AB081167None   I15V, L19I, M36T, R41K, H69K, L89M, I93LC
Brindeiro (2003)BRP2136BRP2136AY213431None   M36T, N37K, R41N, D60E, L63P, H69K, L89M, I93LC
 BRC1525BRC1525AY213520None   I13V, I15V, M36T, N37K, R41N, H69K, L89I, I93LC
Gordon (2003)ZA066p01ZA066p01AY137004None   T12S, I15V, G16E, L19I, M36T, N37S, R41K, L63T, H69K, L89M, I93LC
Soares (2003)BRP2022BRP2022AF527205None   L10I, M36T, N37K, R41N, H69K, L89M, I93LC
 BRP2073BRP2073AF527284None   Q2K, I15V, G16A, M36T, N37K, R41N, H69KC
 BRP2089BRP2089AF527305None   L10V, I15V, M36T, N37K, R41N, L63V, H69K, L89M, N98KC
Balakrishnan (2005)YRG21YRG21AY787507None   I13V, K14R, I15V, L19I, M36T, R41K, L63P, H69K, L89M, I93LC
Non-B Workgroup (2005)BR1001BR1001AY900898None   L10I, M36T, N37K, R41N, H69K, L89M, I93LC
 BR1018BR1018AY900912None   Q2K, I15V, G16A, M36T, N37K, R41N, H69KC
 BR1024BR1024AY900915None   L10V, I15V, M36T, N37K, R41N, L63V, H69K, L89M, N98KC
Bessong (2006)POB_01PB16ZA01PB16ZADQ222248None   T12S, I15V, G16E, L19I, M36T, N37T, P39S, R41K, D60E, Q61E, L63S, H69K, T74A, L89M, I93LC
Rousseau (2006)Pt7303PS136MB1DQ351231None   L19V, M36T, R41K, L63V, I64L, H69K, L89M, I93LC
 Pt11303SK086B1DQ164124None   T12P, K14R, L19I, M36T, G40R, R41K, L63P, H69K, K70R, G86R, L89M, I93L, G94RC
Santos (2006)058PR058PRAY275776None   I15V, L19V, M36T, N37K, R41N, L63T, H69K, L89M, I93LC
 C076PRC076PRDQ191012None   I15V, M36T, N37K, R41N, L63T, H69K, L89M, I93LC
 C077PRC077PRDQ191013None   L10I, M36T, N37K, R41N, L63P, H69K, L89M, I93LC
Sen (2007)N029RT29-PLEF186939None   T12S, I15V, L19T, M36T, R41K, L63P, H69K, I93LC
Soundararajan (2007)TRC24TRC24EF491938None   T12TS, I15V, L19T, M36T, R41K, L63P, H69K, V77I, L89M, I93LC
Vidal (2007)U070202BU.U0702AM260287None   T12S, I15V, L19V, M36T, N37K, R41N, K45R, H69K, L89M, I93LC
Arora (2008)50PI-50 None   I13V, I15V, L19I, M36T, R41K, L63P, H69K, L89M, I93LC
Ibe (2008)9999AB356162None   I15V, G16E, M36T, N37K, R41N, H69K, L89I, I93LC
Marconi (2008)SW012sw012EU308030None   T12S, I15V, G16E, L19V, M36T, N37D, R41K, D60E, L63T, I64L, H69K, I72V, V77I, L89M, I93LC
 SW076sw076EU308087None   T12S, I15V, L19T, M36T, R41K, D60E, H69K, L89M, I93LC
Matthews (2008)A373A373FJ199572None   T12S, I15V, L19V, M36T, R41K, L63S, H69K, L89M, I93LC
 PS037PS037FJ199618None   T12S, I15V, L19I, M36T, R41K, H69K, L89M, I93LC
 PS136PS136FJ199705None   L19V, M36T, R41K, L63V, I64L, H69K, L89M, I93LC
 PS368PS368FJ199787None   T12S, I15V, G16E, L19I, M36T, P39S, R41K, D60E, I62V, H69K, L89M, I93LC
 SK086SK086FJ199887None   T12P, K14R, L19I, M36T, G40R, R41K, L63P, H69K, K70R, G86R, L89M, I93L, G94RC
 SK135SK135FJ199912None   I15V, L19I, E35D, M36T, R41K, H69K, L89MC
 SK161SK161FJ199933None   L19T, M36T, L63P, H69K, L89M, I93LC
Pillay (2008)DR69DR69AY589918None   T12S, I15V, L19I, E35D, M36T, R41K, D60E, Q61E, L63P, H69K, V82I, L89M, I93LC
Brown (2009)CAS_1350_4_1257CAS_1350_4_1257FJ030696None   L10V, I15V, M36T, N37K, R41N, H69K, L89M, I93LC
Iqbal (2009)100127100127EU449542None   T12S, K14R, I15V, G16E, L19I, M36T, R41K, L63S, H69K, L89M, I93LC
 100186100186EU449543None   T12S, K14R, I15V, L19T, M36T, R41K, L63P, H69K, L89LM, I93LC
Bonura (2010)1223_1161223_116GU969560None   L10V, I15V, G16GE, M36T, N37K, R41N, L63T, H69K, L89I, I93LC
Djoko (2010)625CD2644FR666625None   T12S, I15IV, L19IM, M36T, N37D, R41K, L63T, H69K, V77I, L89M, I93LC
Wright (2010)300SK300HM593304None   T12S, I15V, L19V, M36T, P39PS, R41K, L63LP, H69K, L89M, I93LC
 372SK372HM593379None   I15V, L19I, M36T, R41K, R57K, H69K, L89M, I93LC
Ferreira (2011)BRMT2564BRMT2564HQ638713None   T12A, I15V, G16E, M36T, N37K, R41N, L63H, H69K, L89I, I93LC
 BRMT2822BRMT2822HQ638727None   I15V, M36T, N37K, R41N, K45R, H69K, L89I, I93LC
Graf (2011)SC02SC02JF773982None   M36T, N37K, R41N, Q61D, L63E, H69K, I93LC
 SC38SC38JF774005None   L10I, I15V, M36T, N37K, R41N, L63T, C67G, H69K, L89I, I93LC
 SC40SC40JF774007None   L10V, I15V, M36T, N37K, R41N, H69K, L89M, I93LC
 SC56SC56JF774019None   G17E, Q18P, L19V, M36T, N37K, R41N, H69K, L89M, I93LC
 SC97SC97JF774036None   I15V, M36T, N37K, R41I, L63I, H69K, T74S, L89I, I93LC
Hamers (2011)CP763A03387CP763A03387HQ994646None   I15V, L19V, E35D, M36T, N37E, L63P, H69KC
Manasa (2011)10001911000191JN664971None   T12S, I15V, L19I, M36T, L63T, E65D, H69K, V82I, L89M, I93LC
Sanabani (2011)BR2040BR2040JN692442None   L10I, I15V, L19I, M36T, N37K, R41N, L63T, C67G, H69K, L89I, I93LC
Santos (2011)J151J151_PR_RTJN010536None   L10V, I15V, M36T, N37K, R41N, H69K, L89LMC
 J195J195_PRJN010601None   L10V, I15V, M36T, N37K, R41S, H69K, L89M, I93LC
 J211J211_PRJN010622None   I13V, I15V, M36T, N37K, R41N, H69K, L89M, I93LC
 J271J271_PRJN010673None   T12K, I15V, G16E, L19I, M36T, N37K, P39S, R41N, H69K, L89M, I93LC
 J332J332_PR_RTJN010707None   T12K, I15V, G16E, M36T, N37K, R41N, H69K, L89M, I93LC
 J342J342_PR_RT_CN_RHJN010722None   I15V, L19LI, M36T, N37K, R41N, H69K, L89I, I93LC
Thorat (2011)Pat029IN-NARI-HIVDR-5-029HQ166867None   T12S, I15V, L19M, M36T, N37A, R41K, L63P, C67Y, H69K, L89M, I93LC
Chen (2012)YN10DH0094YN10DH0094JQ658715None   T12S, I15V, L19I, M36T, N37D, R41K, L63P, H69K, K70KR, I72V, I93LC
da Silveira (2012)BRMS47BRMS47JF342298None   L10V, I13V, I15V, L19I, M36T, N37K, R41N, K43R, L63T, H69K, L89I, I93LC
De Gascun (2012)IRL20744IRL20744JN622999None  Q58ET12P, L19I, M36T, R41K, I62V, L63PS, H69K, T74A, L89M, I93LC
Hunt (2012)GP07_225683GP07_225683KF736605None   L10I, T12S, I15V, G16E, L19I, E35D, M36T, R41K, L63T, H69K, L89M, I93LC
 GP07_224825GP07_224825KF736604None   T12S, I15V, L19I, M36T, N37E, H69K, L89M, I93LC
Ssemwanga (2012)5675HR5675HRJF800227None   L10V, I15V, G16E, L19I, E35D, M36T, N37K, P39S, R41N, H69K, L89M, I93LC
Alencar (2013)SP2-0041SP2-0041JQ238082None   I15V, M36T, N37K, R41N, K45KR, L63T, H69K, I72IV, T74S, L89I, I93LC
Bila (2013)MZ10-269HIV-1KF927357None   I15IV, Q18QK, L19IT, M36T, N37D, L63P, H69K, L89M, I93LC
 MzBei151HIV-1KF927358None   T12S, I15V, L19I, M36T, R41K, L63P, H69K, I93LC
 MZ10-146HIV-1KF927253None   T12S, I15V, L19V, M36T, N37S, R41K, L63V, H69K, L89M, I93LC
Ferreira (2013)BR09SP603BR09SP603HM534043None   I13V, I15V, M36T, N37K, R41N, L63P, H69K, L89M, I93LC
Frentz (2013)EHR-41332EHR-41332JX300239None   I15V, L19T, K20T, M36T, R41K, L63V, H69K, V82I, I93LC
Leye (2013)SN.MS821SN.MS821FM210741None   L19I, M36T, R41K, L63S, H69K, L89M, I93LC
 SN.MS456SN.MS456FM210713None   L19T, M36T, R41K, L63S, H69K, L89M, I93LC
Mulu (2013)ETH-G-5735ETH-G-5735KF026179None  L33IKT12S, I13V, L19T, E34EK, M36T, R41K, K45R, D60E, Q61E, L63P, H69K, L89M, I93LC
 ETH-G-5713ETH-G-5713KF026204None   T12S, I15V, L19I, M36T, R41K, L63P, H69K, L89M, I93LC
Van Zyl (2013)10351267KC423015None   T12S, I15V, L19I, M36T, R41K, L63Q, H69K, L89M, I93LC
 12441349KC423080None   T12S, I15V, L19I, M36T, R41K, L63Q, H69K, L89M, I93LC
 63693KC424372None   T12S, I15V, L19I, M36T, R41K, L63P, H69K, K70R, L89M, I93LC