<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation E35N
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 17
Isolates 20
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK231UK231AY900765RTV, NFV26L90ML33I, K43TQ18L, L19T, K20X, E35N, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, L89M, I93LC
Weber (2005)M72003M72003AY677426NFV, RTV, IDV212I54IV, L90ML10FI13V, K14N, I15V, L19I, K20T, E35N, M36I, R41K, K45R, I62IV, L63P, I64V, H69K, K70R, T74S, L89M, I93LC
Van Zyl (2013)13341229KC422979LPV26  L10I, T12S, I15V, L19T, K20R, E35N, M36I, R41K, H69Q, L89M, I93LC
  1657KC423304LPV26  L10I, T12S, I15V, L19T, K20R, E35N, M36I, R41K, H69Q, L89M, I93LC
 13542013KC423563LPV104  T12S, I15V, L19I, K20R, E35N, M36I, N37D, R41K, R57RK, D60E, L63V, H69K, T74S, L89M, I93LC
 590269KC423787LPV26  T12S, I15V, L19T, K20R, E35N, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93LC
Grossman (2014)609609KF135112LPV52M46I, I54V, V82A, L90MN83D, L89VL10I, V11L, I13A, K20R, A22V, E35N, M36I, N37D, R41K, I62V, L63P, H69K, A71V, I93LC
  609 LPV134M46I, I54V, V82A, L90MG73S, N83D, L89VL10I, V11L, I13V, K20R, A22V, E35N, M36I, N37D, R41K, K55R, I62V, L63P, H69K, A71V, T91S, I93LC
  609 LPV292M46I, I54V, V82A, L90MG73GS, N83D, L89VL10I, V11L, I13AV, K20R, A22V, E35N, M36I, N37D, R41K, K55R, R57RK, I62V, L63P, H69K, A71IV, T91S, I93LC
 613613KF135114NFV, LPV52L90M Q7R, I15V, L19T, K20I, E35N, M36I, R41K, K43R, H69K, T74S, L89I, I93LC
 4949KF135089NFV, LPV52I54V, V82A, L90ML10F, L33F, T74PI13V, I15V, G16E, K20MT, E35N, M36I, R41K, R57K, Q61QHKN, I62IV, L63T, H69K, A71V, I93LC
 183183KF135005NFV, LPV52M46I, I54V, V82F, L90M L10I, I13V, I15V, L19T, K20T, E35N, M36I, R41K, K45R, H69K, A71T, T74S, V77I, L89I, I93L, C95YC
Diaz (2015)RenG17227RenG17227KT748255PINA L23IL10M, I13V, K20T, E35N, M36I, N37K, R41N, K45Q, I62V, L63P, H69K, T74K, V82VI, L89I, I93LC
 RenG17053RenG17053KT748081PINAI50L, L90ML33IL10Y, I13IV, I15V, K20T, E34EQ, E35N, M36I, N37E, R41N, K45R, D60N, I62IV, L63LP, C67CF, G68GE, H69KR, A71I, L89I, I93LC
 RenG16791RenG16791KT747819PINAM46I, I54V, V82A, L90ML10F, L33F, T74PI13V, I15V, K20T, E35N, M36I, N37Q, R41N, I62IV, L63V, H69K, I72V, L89I, I93LC
 RenG14709RenG14709KT745737PINAD30N, M46MI, V82AL10F, L24I, L33F, N88DT12P, I15V, K20T, E35N, M36I, N37K, R41N, K45R, L63P, H69K, V75I, I93LC
 RenG14916RenG14916KT745944PINAI50L, V82M, L90ML23I, L33FI13V, I15V, K20T, E35N, M36I, N37K, R41N, Q61E, L63PS, H69KN, A71V, T74S, L89I, I93LC
 RenG12519RenG12519KT743547PINAM46I, I54V, V82A, L90ML10F, L23II13V, K14R, I15V, K20I, E35N, M36I, N37E, R41N, Q61H, I62V, L63P, H69K, A71T, T74S, L89I, I93LC
 RenG11410RenG11410KT742438PINAI54V, V82A, L90M L10V, I13A, K20V, A22V, E35N, M36I, N37K, R41H, R57RK, D60E, I62V, L63P, I64V, H69K, A71V, I93MC
Rossouw (2015)RP152RP152KT032054LPV80  L5LF, T12S, K14R, I15V, L19V, K20R, L23LF, E35N, M36I, N37D, R41K, L63V, H69K, L89MC