Protease Inhibitors

HOME Genotype-Rx Genotype-Pheno Genotype-Clinical hivdb program

Protease Inhibitors

Subtype	C
Gene	PR
Mutation	E35D
Rx	>= 1 PI
IncludeMixtures	No

References	27
Patients	129
Isolates	157

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	Wks	PIMajorDRMs	PIMinorDRMs	OtherMut	Subtype
Weidle (2001)	PW_UG4393	PW_UG4393	AF358747	RTV	51			I13V, K14R, E35D, M36I, R41K, H69K, L89M	C
Gibb (2002)	DMG104	104_w66		NFV	66	N88S	Q58QE	T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, D60E, Q61E, L63P, H69K, L89M, I93L	C
	DMG78	78_w9		NFV	9	D30DN, L90LM	L89MV	T12S, I15V, L19I, E35D, M36L, N37E, D60E, L63P, I64IV, H69K, I93L	C
		78_w30		NFV	30	D30N	N88ND, L89MV	T12S, I13IV, I15V, L19I, E35D, M36L, N37E, K45KQR, D60E, L63P, H69K, I93L	C
	DMG85	85_w19		NFV	17			T12S, I15V, L19I, E35D, M36I, R41K, D60DE, L63LAPV, H69K, V82I, L89M, I93L	C
		85_w29		NFV	27			T12S, I15V, L19I, E35D, M36I, R41K, K45R, D60E, Q61E, L63P, H69K, L89M, I93L	C
		85_w50		NFV	36			T12S, I15V, L19I, K20KT, E35D, M36I, R41K, L63LV, H69K, V82I, L89M, I93L	C
	DMG86	86_w82		NFV	65	D30N	L10F, N88D, L89V	T12S, I13V, I15V, L19I, E35D, M36L, N37E, K45R, D60E, L63P, H69K, I93L	C
	DMG91	91_w22		NFV	22	D30N	L10F, N88D, L89V	T12S, I13V, I15V, L19I, E35D, M36L, N37E, K45R, D60E, L63P, H69K, I93L	C
	DMG95	95_w75		NFV	75			I15V, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L	C
Kantor (2002)	TCDD-01	TCDD-01	AY090840	NFV	22			T12S, I15V, L19I, K20R, E35D, M36I, N37D, R41K, R57K, I62V, L63I, E65D, H69K, V82I, L89M, I93L	C
	TCDD-29	TCDD-29	AY090855	SQV	140	L90M		I15V, G16E, K20KR, E21EK, E35D, M36I, P39S, R41K, K45R, D60E, L63P, H69K, A71AV, L89M, I93L, F99X	C
	TCDD-30	TCDD-30_1	AY090856	NFV, IDV	14			L10I, T12A, I15V, L19I, E35D, M36I, N37ND, R41K, H69KQ, L89M, I93IL	C
	TCDD-32	TCDD-32	AY090858	RTV	18			T12S, I13LV, K14EQ, L19I, E35D, M36I, R41K, L63V, H69K, T74S, L89M, I93L	C
Snoeck (2002)	BE4	BE4b		NFV	48			K14R, I15V, L19I, E35D, M36I, R41K, H69K, L89M, I93L	C
	BE8	BE8	AF338992	IDV	80			I15V, L19V, E35D, M36L, R41K, L63V, H69K, T74S, L89M, I93L	C
Johnston (2003)	TC-60	TC-60		IDV	104	I54IV, V82A		I15V, E35D, M36I, R41K, L63P, H69K, A71AT, I93L	C
	TC-71	TC-71		IDV	52	G48V, I54T, V82A		L10I, I15V, L19I, K20R, E35D, M36I, R41K, L63V, H69K, A71V, T74S, L89M, I93L	C
Weber (2003)	85H	610185H-12	AY140821	RTV	13			L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69K, T74S, V77I, L89M, I93L	C
		610185H-48	AY140823	RTV	48	I54V, V82A		L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69R, T74S, V77I, L89M, I93L	C
Colonno (2004)	RC-008-060-076	060-07621	AY461494	ATV	80	I50L		T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, L89M, I93L	C
	RC-007-045-235	045-2351	AY461491	ATV		M46I, I50IL		T12S, I15V, L19T, E35D, M36I, R41K, K45R, K55H, R57K, L63IT, H69K, I93L	C
	RC-008-060-169	060-1691	AY461495	ATV		I50L		T12S, I15V, G16GE, L19I, K20R, E35D, M36I, R41K, H69KQ, L89M, I93L	C
	RC-034-067-562	067-5621	AY461501	ATV		I50L		K14R, I15V, L19I, K20T, E34EK, E35D, M36I, N37D, R41K, K55KN, D60E, I64IV, H69K, A71V, L89MT, I93L	C
Gomez-Carrillo (2004)	96105	96105	AY365516	PI	NA			T12A, I15S, G16R, E35D, M36I, N37K, R41N, L63T, H69K, I72T, T74S, L89M, I93L	C
Grossman (2004)	IL128	IL128c	AY529543	NFV	52			I15IV, D29DV, E35D, M36I, R41K, L63LP, H69K, L89M, I93L	C
		IL128d	AY529544	NFV	65	D30DN		I15IK, E35D, M36I, R41K, L63P, I64IL, E65ED, H69K, L89M, I93L	C
		IL128e	AY529545	NFV	74	D30N		K14N, E35D, M36I, R41K, L63LP, H69K, L89M, I93L	C
	IL48	IL48	AY529529	IDV	136			I15V, E35D, M36I, R41K, K45R, H69K, L89M, I93L	C
	IL49	IL49	AY529530	NFV	64	N88NS, L90LM		Q7QK, L10LI, I15V, G16E, K20RT, E35D, M36I, L38LM, R41RK, R57K, L63T, H69K, T74TS, L89M, I93L	C
	IL178	IL178	AY529547	NFV	65	N88S		L19KT, K20T, T31TK, E35D, M36I, R41K, K45KR, L63P, H69K, L89M, I93L	C
	IL185	IL185c	AY529558	NFV	132	D30N		T12S, I15V, L19I, E35D, M36I, R41K, K45R, H69K, I85V, L89I, I93L, N98NI	C
	IL197	IL197a	AY529559	NFV	34			T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, L89M, I93L	C
	IL217	IL217	AY529576	NFV	104	D30N	N88D	L10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, I64IV, H69Q, L89IM, I93L	C
	IL267	IL267	AY529619	IDV, RTV, SQV, NFV	229	L90M		I13IV, K14R, I15V, G16GE, K20T, E35D, M36I, R41K, H69K, A71AV, T74S, L89I, I93L	C
	IL287	IL287	AY529620	SQV, RTV, IDV, NFV	184	I84V, L90M		L5LI, L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63T, H69K, A71V, T74S, I93L	C
	IL401	IL401	AY529596	NFV	209	L90LM		L10R, V11F, K14R, D29DV, E35D, M36V, N37ND, R41K, L63P, I64IV, H69K, I72IV, L89LM, I93L	C
	IL477	IL477	AY529602	NFV	208	D30N	L10F, N88D	T12S, I15V, L19V, K20T, E35D, M36I, N37D, R41K, L63V, I64M, H69K, L89M, I93L	C
Montes (2004)	MB_patNIB	01_NIB719	AJ577965	NFV	94	L90M	L23I	T12S, I13V, I15V, L19I, K20T, E35D, M36I, N37R, R41N, Q61E, L63A, I64M, H69K, V82I, L89M, I93L	C
Snoeck (2004)	BE42	BE42	AY900745	NFV	31			I15V, E35D, M36I, N37NS, R41K, H69K, T74S, L89M, I93L	C
Non-B Workgroup (2005)	UK320	UK320	AY900769	NFV	57	L90M		T12S, I15V, L19I, K20T, E35D, M36I, R41K, H69K, T74S, L89I, I93L	C
	UK449	UK449		SQV, NFV, RTV		L90M	L23I	T12S, L19I, E35D, M36I, R41K, D60E, L63S, H69K, V82I, L89M, I93L, L97X	C
	UK773a	UK773a		NFV				P9PL, T12S, I15IV, L19T, K20R, E35D, M36I, R41K, L63V, H69K, T74S, L89M, I93L	C
	UK955	UK955	AY900786	SQV, RTV, IDV	137	I54V, I84V, L90M	G73S, L89V	L10I, I15V, L19I, K20X, E35D, M36I, R41K, D60E, I62IV, L63P, H69K, A71V, I85V, I93L	C
	UK973	UK973	AY900789	NFV	54			T12S, I15V, L19T, K20KT, E35D, M36I, R41K, L63T, H69K, T74S, L89M, I93L	C
	UK1147	UK1147	AY900794	IDV, NFV	117	M46I	K43T	T12S, I15V, L19I, K20T, E35D, M36I, N37D, D60E, Q61E, L63P, H69K, A71T, L89T, I93L	C
	UK1154	UK1154	AY900795	NFV		L90M		T12S, I13V, I15V, L19I, K20T, E35D, M36I, R41K, D60E, L63P, I64V, H69K, V82I, L89M, I93L	C
	UK1461	UK1461	AY900805	NFV	35		L23I	T12S, I15V, L19I, K20T, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93L	C
	UK1518	UK1518	AY900807	NFV	68	D30N	N88D	T12S, I15V, L19V, K20T, E35D, M36I, N37NS, R41K, H69K, T74S, L89M, I93L	C
	IL224	IL224	AY900815	SQV, RTV, IDV	239			K14R, E35D, M36I, N37D, R41K, H69K	C
	UK1461b	UK1461b		NFV	35	L90LM	L23I	T12S, I15V, L19I, K20T, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93L	C
	UK1447b	UK1447b	AY900833	IDV, NFV, SQV, RTV, APV, LPV	175	M46I, I50V, I54V, V82A, L90M	L10F, L23I, K43T	I15V, K20R, E35D, M36I, R41K, I62V, L63V, H69K, A71V, T74S, L89I, I93L	C
	UK2064	UK2064		IDV	150			I15V, L19I, E35D, M36I, R41K, L63V, H69K, T74S, L89M, I93L	C
	UK2055	UK2055	AY900844	SQV	141			T12S, I15V, L19T, E35D, M36I, N37NT, R41K, H69K, L89M, I93L	C
	UK2069	UK2069	AY900845	NFV		D30N	N88D	T12S, I13V, I15V, Q18H, L19I, K20R, E35D, M36I, R41K, L63V, H69K, T74S, L89I, I93L	C
	BR6	BR6	AY900885	SQV, RTV, IDV	306	I54V, I84V, L90M	L89V	L10V, I13V, I15V, G16A, K20M, E35D, M36I, N37K, R41N, D60E, L63P, H69K, A71V, I93L	C
	BR42	BR42	AY900895	NFV	97	M46I, L90M		L10V, E35D, M36I, N37K, R41N, L63P, I64V, H69K, L89M	C
	SA75_DR16	SA75_DR16	AY901099	NFV		D30N	L10F, V32VA, N88D	I15IL, G16E, L19I, E35D, M36IV, R41K, Y59YF, Q61E, I62IV, H69K, T74S, L89M, I93L, N98K	C
	SA84_DR29	SA84_DR29	AY901107	NFV				T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, H69K, T74S, L89M, I93L	C
	TK1004	TK1004		NFV, RTV, IDV	131			I3IV, T12P, I15V, L19I, K20T, E21G, E35D, M36I, N37D, R41K, K45R, L63P, I64L, H69K, T74A, L89M, I93L	C
		TK1004a		NFV, RTV, IDV	183			T12P, I15V, L19I, K20T, E35D, M36I, N37D, R41K, K45R, L63P, I64L, H69K, T74S, L89M, I93L	C
		TK1004b		NFV, RTV, IDV	196			T12P, I15V, L19I, K20T, L24LF, E35D, M36I, N37D, R41K, K45R, L63P, I64L, H69K, T74S, L89M, I93L	C
		TK1004c		NFV, RTV, IDV	268			T12P, I15V, L19IT, K20T, E35D, M36I, N37D, R41K, K45R, L63P, I64L, H69K, T74S, L89M, I93L	C
	TK1020	TK1020		SQV, RTV, IDV	211	I54V, V82C, L90M	F53L	L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55H, L63P, H69K, T74A, L89M, I93L	C
		TK1020a		SQV, RTV, IDV, LPV	229	M46L, I54V, V82C, L90M	L23I, F53L	L10I, I15V, L19I, K20R, E35D, M36I, N37D, K55H, L63P, H69K, T74A, L89M, I93L	C
		TK1020b		SQV, RTV, IDV, LPV	392	M46I, I47V, I54V, V82C, L90M	L23I, K43T, F53L	L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55H, I62V, L63P, H69K, T74E, L89M, I93L	C
	TK1021	TK1021		IDV, RTV, LPV	331	M46I, I54V, V82A	L10F, L24I, Q58E	T12S, L19I, E35D, M36I, N37D, R41K, K55R, D60E, Q61E, I62V, L63P, H69K, L89M, I93L	C
		TK1021a		IDV, RTV, LPV	332	M46MI, I54IV, V82VA	L10LF, L24LI, Q58QE	T12S, I15IV, L19IV, E35D, M36I, N37D, R41K, K55KR, D60E, Q61E, I62IV, L63P, H69K, L89M, I93L	C
	TK2024	TK2024a		IDV, RTV, SQV	216			T12S, I15V, L19I, E35D, M36I, N37D, L63LP, H69K, L89M, I93IL, L97Q	C
		TK2024b		IDV, RTV, SQV	275			T12S, I15V, L19I, E35D, M36I, N37ND, R41RK, L63LP, H69K, L89M, I93IL	C
	TK3009	TK3009		SQV, NFV	158	L90M		K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93L	C
		TK3009a		SQV, NFV, LPV	232	L90M		I13V, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93L	C
		TK3009b		SQV, NFV, LPV	232	L90M		I13IV, K20R, E35D, M36I, N37D, R41K, L63P, H69K, T74S, L89M, I93L	C
	TK3015	TK3015		SQV, IDV	204	I54V, V82A, L90M	K43T	L10I, T12S, I15V, L19I, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93L	C
		TK3015a		SQV, IDV, LPV	264	I54V, V82A, L90M	L10F, K43T	T12S, I15V, L19K, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93L	C
		TK3015b		SQV, IDV, LPV	283	I54V, V82A, L90M	L10F, K43T	T12P, I15V, L19K, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93L	C
		TK3015c		SQV, IDV, LPV, RTV, TPV	375	I54V, V82T, I84IV, L90M	K43T	L10I, T12S, I15V, L19I, K20IR, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, L89LM, I93L	C
	TK3016	TK3016		SQV, NFV	167	I54V, L90M	T74P	L10V, I15V, E35D, M36I, R41K, H69K, A71V, L89M, I93L	C
	TK3019	TK3019		SQV, NFV, RTV	143	I54V, I84IV, L90M	V11VI, G73S	L10I, I13V, I15V, L19I, K20R, E35D, M36I, R41K, K45R, I62V, L63P, H69T, A71V, I72L, I93L	C
		TK3019a		SQV, NFV, RTV	149	L90M	G73S, T74AP	I15V, L19I, E35D, M36I, R41K, I62V, L63P, H69T, A71V, I72L, I93L	C
	TK3020	TK3020		RTV, NFV, SQV	120			T12S, I15V, L19I, E35D, M36I, R41K, L63AT, H69K, T74S, L89I, I93L	C
		TK3020a		RTV, NFV, SQV	120			T12S, I15V, L19I, E35D, M36I, R41K, L63T, H69K, T74S, L89I, I93L	C
	TK3022	TK3022		SQV, NFV	103			T12S, I15V, L19I, K20R, E35D, M36I, K43R, L63T, H69K, L89M, L97LI	C
	TK3024	TK3024		SQV, NFV	205	L90M		T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45R, L63P, H69K, A71I, T74S, I93L	C
		TK3024a		SQV, NFV, LPV	246	L90M		T12S, I15V, L19I, K20T, E35D, M36I, R41K, K45KR, L63P, H69K, A71I, T74S, I93L	C
	TK3026	TK3026		RTV, SQV, NFV	292	L90M		I15V, L19I, K20T, E35D, M36I, R41RK, L63P, H69K, A71I, T74S, L89I, I93L	C
	TK3027	TK3027		RTV, SQV, NFV	190	D30N, L90M	N88D	T12S, I13V, I15V, L19I, K20R, E35D, M36I, N37D, I62IV, L63P, H69K, T74S, L89I, I93L	C
		TK3027a		RTV, SQV, NFV, LPV	259			T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, L89M, I93L	C
		TK3027b		RTV, SQV, NFV, LPV	276	D30DN, L90LM	N88D	T12S, I13IV, I15V, L19I, K20R, E35D, M36I, N37ND, R41RK, L63P, H69K, T74S, L89IM, I93L	C
	TK3032	TK3032		SQV, IDV	239	M46I, I54V, V82T, L90M		L10R, T12S, I15V, L19I, K20R, E35D, M36I, R41K, I62V, L63P, G68GE, H69K, L89M, I93L, C95F	C
	TK3035	TK3035		IDV, NFV, RTV	202	I54A, V82A		L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K45KR, D60E, L63P, H69K, A71V, L89M, I93L	C
	TK5007	TK5007		IDV, RTV	261		G73ST	L10I, T12S, I15V, L19I, E35D, M36I, N37S, R41K, K45R, I62V, L63P, H69K, I85V, I93L	C
	PL27956	60622		NFV, RTV, IDV	184	L90MR		L10V, T12S, I15V, L19I, K20R, E35D, M36I, R41K, I62IV, L63P, H69K, A71AV, T74S, V77VI, I93L	C
	PL4725	58294		Unknown, LPV	>4	G48V, I54V, V82T, L90M	Q58E	L10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L	C
		69936		Unknown, LPV	>51	G48V, I54V, V82S, L90M	Q58E	L10V, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95CF	C
		80404		Unknown, LPV	>90	G48V, I54V, V82S, L90M	Q58E	L10V, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55R, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95F	C
		100703		Unknown, LPV, APV	>159	M46ML, G48V, I54V, V82S, L90M	V11VI, L33F, Q58E	L10V, I13V, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55R, I62V, L63P, H69K, K70KR, A71T, I72IM, T74S, I85V, L89I, I93L, C95F, T96S	C
	PL52496	99430		IDV	191			T12S, I15V, L19I, E35D, M36I, R41K, D60E, L63H, H69K, L89M, I93L	C
Weber (2005)	F77878	F77878	AY677381	Unknown, NFV	>133	L90M		G17D, K20R, E35D, M36I, L63Q, I64V, H69K, L89M, I93L	C
	F30356	F30356	AY677479	Unknown, NFV	>201	I54V, V82A, L90M		L10I, T12S, I15V, L19T, K20R, E35D, M36I, N37H, P39PS, R41K, K45R, L63P, H69KQ, A71I, I93L	C
	F62043	F62043	AY677411	NFV	85			T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, L89M, I93L	C
	939949	939949	AY714411	LPV	22			T12S, I15V, L19M, E35D, M36I, H69K, L89M, I93L	C
Baxter (2006)	12-1007	1007-30519	DQ875953	PI	NA	M46L, I54IV, V82A, L90M	L33F, K43KT	L10I, I15V, L19T, K20R, E35D, M36I, R41K, Q61E, I62IV, L63P, H69K, T74S, L89M, I93L	C
	12-1716	1716-30421	DQ876854	PI	NA	M46L, I54V, V82A, I84V	L24I, L33F, K43T	L10I, I15V, K20R, E35D, M36I, N37ND, R41K, I62V, L63T, H69K, T74S, L89M, I93L	C
	12-3102	3102-30610	DQ877250	PI	NA	L90M	L23I, L33F, F53L, Q58E	L10I, T12P, I15V, G16E, L19V, K20R, E35D, M36I, N37T, I62V, L63T, H69K, T74A, V82I, I85V, L89M, I93L	C
	48-1407	1407-30410	DQ877803	PI	NA	I54V, V82A, L90M	L10FI, K43T	T12PS, I15V, L19IK, K20I, E35D, M36I, R41K, D60E, Q61E, I62IV, L63P, H69K, A71V, I85V, I93L	C
	48-2254	2254-30930	DQ877888	PI	NA	G48V, I54V, V82S, L90M	L33F, Q58E	L10V, I13IV, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55R, R57RK, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93L, C95F, T96TS	C
	48-3058	3058-30401	DQ877970	PI	NA	I54L, V82A, L90M	L33F, K43KT	L10I, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63P, H69K, T74S, L89M, I93L	C
	48-3229	3229-30523	DQ878136	PI	NA	M46I, I54V, V82A, I84V	L10F, L24I, L33F, K43T	T12S, I13V, L19I, K20M, E35D, M36I, R41K, L63V, I64V, H69K, T74S, L89I, T91S	C
	48-4006	4006-30326	DQ878240	PI	NA			L10LV, T12S, I15IV, L19I, E35D, M36I, R41K, K45KR, D60E, H69K, L89M, I93L	C
	48-7101	7101-30723	DQ878954	PI	NA	M46I, I54V, V82A	L10F, L24I	T12P, I13V, L19I, K20I, E35D, M36I, R41K, L63P, H69K, T74AS, L89M, I93L	C
	48-9302	9302-30918	DQ877587	PI	NA	I54V, V82A, L90M	L10F, G73GS, L89IMV	I15V, K20I, E35D, M36I, N37K, R41N, Q61H, L63P, H69K, A71V, I85V, I93L	C
Doualla-Bell (2006)	Pt1	FDB_Pt1		NFV		D30N		T12S, I15V, G16A, L19I, K20T, E35D, M36I, R41K, K45Q, D60E, C67E, H69K, L89IM, I93L	C
	Pt10	FDB_Pt10		NFV		D30N, L90M	L33F	I15V, G17D, L19V, E35D, M36I, N37K, R41K, L63P, H69K, A71V, I93L	C
	Pt3	FDB_Pt3		NFV		D30N		T12S, I15V, L19V, K20T, E35D, M36I, R41K, K45Q, D60E, Q61E, L63P, H69K, V75I, I93L	C
	Pt4	FDB_Pt4		NFV		L90M		K14R, I15V, L19I, K20T, E35D, M36I, R41K, D60E, Q61E, I64V, H69K, L89M, I93L	C
	Pt5	FDB_Pt5		NFV		N88S	L10F	I15V, L19I, K20T, E35D, M36I, R41K, Q61H, L63T, H69K, T74S, L89M, I93L	C
	Pt7	FDB_Pt7		NFV		D30N	L33F	L10M, V11F, I13V, I15V, K20R, E35D, M36I, R41K, I62V, L63T, H69K, I93L	C
McGrath (2007)	2	DMG_2a		RTV, ATV	48			T12S, I15V, L19I, K20R, E35D, M36I, R41K, H69K, L89M, I93L	C
von Wyl (2007)	132	5062429	EF449853	PI	NA			I13IV, E35D, M36I, R41K, K43R, H69K, L89M	C
	19	702313	EF449901	PI	NA	I54IV, N88NS, L90M		L10V, T12K, I15V, G16E, L19I, K20R, E35D, M36IV, N37Q, P39Q, R41N, D60DN, Q61QH, I62V, L63T, H69K, A71AV, I72IT, T74A, L89M, I93L	C
	41	662849	EF449918	PI	NA	D30N	N88D	I15V, E35D, M36I, N37K, R41HN, L63P, H69K, A71AV, I85IV, I93L	C
Marconi (2008)	SW055	sw055	EU308066	LPV	46			T12S, I15V, L19T, K20R, E35D, M36I, R41K, H69K, I72M, T74S, L89M, I93L	C
	SW070	SW070	EU308081	LPV	49	I54V, V82A	L33LF	G16A, L19V, E35D, M36I, R41K, I62V, L63P, H69K, T74S, L89M, I93L	C
	SW090	SW090	EU308099	LPV				T12S, I15V, L19T, E35D, M36I, R41K, K45R, D60E, I62V, L63P, H69K, V82I, L89M, I93L	C
Pillay (2008)	DR58	DR58	AY589910	NFV		D30N		T12S, I13V, I15V, L19I, K20R, E35D, M36I, R41K, K45Q, I64V, H69K, L89I, I93L	C
	DR60	DR60	AY589912	RTV		M46I, N88S		T12S, I15V, L19I, K20I, E35D, M36I, N37D, R41RK, D60E, L63P, H69K, A71AT, I72L, I93L	C
	DR16	02ZA.DR16	AY589877	NFV		D30N	L10F, V32VA, N88D	I15IL, G16E, L19I, E35D, M36IV, R41K, Y59YF, Q61E, I62IV, H69K, T74S, L89M, I93L, N98K	C
	DR29	02ZA.DR29	AY589886	NFV				T12S, I15V, L19I, K20R, E35D, M36I, R41K, R57K, H69K, T74S, L89M, I93L	C
	DR100	03ZA.DR100	AY589936	RTV		M46I, I54V, V82A		I15E, G16GE, L19E, K20R, E35D, M36I, R41K, H69K, L89I, I93L	C
Rosen-Zvi (2008)	71	06p71-2		LPV	12			I15V, Q18E, K20R, E35D, M36I, R41K, D60E, Q61E, I62V, L63V, H69K, T74A, L89M, I93L	C
		09p71-3		LPV	175	I54V, V82A		I15V, Q18E, K20R, E35D, M36I, R41K, K45I, D60E, I62V, L63V, H69K, L89M, I93L	C
Kandathil (2009)	VL07_040	VL07_040	EU030407	PI	NA	M46I, L90M	K43T	T12S, I15V, L19I, K20T, E35D, M36I, R41K, L63P, H69K, T74S, I93L	C
	VL06_192	VL06_192	EU037774	PI	NA			T12S, I15V, L19I, E35D, M36I, N37E, L63T, H69K, T74S, L76X, L89M, I93L	C
Kassaye (2009)	TCDD-05	TC05_2003	FJ445702	SQV	147	L90M		W6W*, P9PR, T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, A71V, I93L	C
	TCDD-30	TC30_2003	FJ445708	NFV, IDV	99	I54V, I84V		L10I, T12A, I15V, L19I, K20KR, E35D, M36I, R41K, L63P, H69Q, L89M, I93L	C
Rhee (2009)	CA14714	CA38172	FJ983395	NFV	48	L90M		T12S, K14R, I15V, L19I, K20T, E35D, M36I, R41K, K45R, L63PS, I64V, H69K, L89M, I93L	C
El-Khatib (2010)	Pat079	11ZA_SAVE1255	JF960529	LPV				T12S, I15V, L19V, E35D, M36I, R41K, K45R, L63T, H69K, T74S, V82VI, L89M, I93L	C
	Pat085	11ZA_SAVE1382	JF960535	SQV, LPV				T12S, I15V, L19T, K20R, E35D, M36I, R41K, H69K, L89M, I93L	C
	Pat092	11ZA_SAVE1489	JF960542	RTV, ATV		N88NS, L90M	L23I, F53FL	T12S, I13V, I15V, L19I, K20T, E35D, M36I, R41K, I62IV, H69K, A71IV, T74S, V77VI, L89I, I93L	C
	Pat094	11ZA_SAVE2003	JF960544	LPV			T74PS	I15V, E35D, M36I, R41K, R57K, H69K, L89M, I93L	C
	Pat098	11ZA_SAVE2040	JF960548	LPV				T12S, I15V, L19I, E35D, M36I, R41K, R57RK, D60E, Q61E, L63P, H69K, L89M, I93L	C
	Pat104	11ZA_SAVE2119	JF960554	LPV				I15V, L19I, K20R, E35D, N37A, P39T, R41K, D60E, L63P, H69K, V77I, L89M	C
	Pat108	11ZA_SAVE2214	JF960558	LPV				T12S, I15V, L19I, K20KR, E35D, M36I, N37ND, R41RK, H69K, L89M	C
	Pat109	11ZA_SAVE2228	JF960559	LPV				T12S, I15V, L19I, K20R, E35D, M36I, R41K, I62V, H69K, T74S, L89M, I93L	C
	Pat117	11ZA_SAVE2359	JF960567	LPV				T12S, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L	C
	Pat129	11ZA_SAVE2478	JF960579	LPV				T12A, I15V, L19I, K20KR, E35D, M36I, R41RK, D60E, Q61E, L63P, H69K, L89M, I93L	C
Rodrigues (2010)	320_07	BR07SC320	GQ401304	LPV				L10V, T12S, I15V, K20R, E35D, M36I, N37K, R41N, H69K, L89M, I93L	C
	301_07	BR07SC301	GQ401314	SQV, RTV, LPV		M46L, G48V, I54V, V82S	L24I, L33F, T74P	L10V, I13V, I15V, G16E, K20M, E34Q, E35D, M36I, N37NKT, R41N, K55R, L63T, H69K, L89M, I93L	C
	307_07	BR07SC307	GQ401316	NFV				L10IV, E35D, M36I, N37K, R41N, H69K, T74S, L89M, I93L	C
	323_07	BR07SC323	GQ401320	LPV				T12P, I15V, L19Q, E35D, M36I, N37K, R41N, L63I, H69K, L89M, I93L	C
Green (2011)	707PKE12F	707PKE12F	HM623503	LPV	81			T12S, I15V, L19I, E35D, M36I, R41K, L63P, H69K, L89M, I93L	C
	707PKE19F	707PKE19F	HM623509	RTV, LPV	131	M46I, I54V, L76V, V82A	Q58E	L10I, T12S, I15V, L19T, K20R, E35D, M36I, R41K, I62V, L63P, H69K, L89M, I93L	C
	707PKE33F	707PKE33F	HM623520	LPV				T12S, I15V, L19V, E35D, M36I, R41K, L63P, H69K, I93L	C
	707PKE38F	707PKE38F	HM623525	LPV	83			L10LI, T12A, I15V, G16GE, E35D, M36I, R41K, K45R, L63APT, H69K, V82VI, L89M, I93L	C
	707PKE49F	707PKE49F	HM623531	LPV	121			T12S, I15V, L19I, K20MR, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, I93L	C
Barber (2012)	51030	51030	JQ361665	LPV		I54V		T12S, I15V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89M, I93L	C

Protease Inhibitors

Database

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