<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation D30N
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 30
Isolates 31
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG7878_w30 NFV30D30NN88ND, L89MVT12S, I13IV, I15V, L19I, E35D, M36L, N37E, K45KQR, D60E, L63P, H69K, I93LC
 DMG8686_w82 NFV65D30NL10F, N88D, L89VT12S, I13V, I15V, L19I, E35D, M36L, N37E, K45R, D60E, L63P, H69K, I93LC
 DMG9191_w22 NFV22D30NL10F, N88D, L89VT12S, I13V, I15V, L19I, E35D, M36L, N37E, K45R, D60E, L63P, H69K, I93LC
Grossman (2004)IL128IL128bAY529542NFV41D30N K14N, A22G, M36I, R41K, H69K, L89M, I93LC
  IL128eAY529545NFV74D30N K14N, E35D, M36I, R41K, L63LP, H69K, L89M, I93LC
 IL160IL160AY529612SQV, NFV128D30NN88DT12S, I15V, L19I, K20I, M36I, P39PS, R41K, K45R, L63T, H69K, A71IV, I93LC
 IL185IL185cAY529558NFV132D30N T12S, I15V, L19I, E35D, M36I, R41K, K45R, H69K, I85V, L89I, I93L, N98NIC
 IL217IL217AY529576NFV104D30NN88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, I64IV, H69Q, L89IM, I93LC
 IL477IL477AY529602NFV208D30NL10F, N88DT12S, I15V, L19V, K20T, E35D, M36I, N37D, R41K, L63V, I64M, H69K, L89M, I93LC
 IL574IL574AY529605NFV56D30N Q7H, R8A, I15V, L19I, K20T, M36I, N37S, R41K, L63S, H69K, I93LC
Non-B Workgroup (2005)UK1518UK1518AY900807NFV68D30NN88DT12S, I15V, L19V, K20T, E35D, M36I, N37NS, R41K, H69K, T74S, L89M, I93LC
 UK2069UK2069AY900845NFV D30NN88DT12S, I13V, I15V, Q18H, L19I, K20R, E35D, M36I, R41K, L63V, H69K, T74S, L89I, I93LC
 SA75_DR16SA75_DR16AY901099NFV D30NL10F, V32VA, N88DI15IL, G16E, L19I, E35D, M36IV, R41K, Y59YF, Q61E, I62IV, H69K, T74S, L89M, I93L, N98KC
 TK3027TK3027 RTV, SQV, NFV190D30N, L90MN88DT12S, I13V, I15V, L19I, K20R, E35D, M36I, N37D, I62IV, L63P, H69K, T74S, L89I, I93LC
 TK3031TK3031 SQV, NFV203D30NN88DI15V, L19I, K20T, E35G, M36I, R41K, G51GR, L63S, H69K, T74A, L89M, I93LC
 PL4706685002 IDV, NFV104D30NN88DT12S, I13V, I15V, L19I, E35ED, M36I, R41K, L63P, H69K, T74A, L89M, I93LC
Rhee (2005)CA7907CA24813AY797580IDV, NFV260D30NL10F, N88DT12P, K14R, I15V, G16E, K20IT, E35G, M36V, R41K, L63T, H69Q, T74S, V77VI, I85IV, L89M, I93LC
Weber (2005)F56949F56949AY677453NFV154D30N T12S, I13V, I15V, L19I, K20T, M36I, R41K, K45T, L63P, H69K, I93LC
Doualla-Bell (2006)Pt1FDB_Pt1 NFV D30N T12S, I15V, G16A, L19I, K20T, E35D, M36I, R41K, K45Q, D60E, C67E, H69K, L89IM, I93LC
 Pt10FDB_Pt10 NFV D30N, L90ML33FI15V, G17D, L19V, E35D, M36I, N37K, R41K, L63P, H69K, A71V, I93LC
 Pt13FDB_Pt13 NFV D30N, M46IL10F, N88DI15V, M36I, R41K, L63P, H69K, I93LC
 Pt3FDB_Pt3 NFV D30N T12S, I15V, L19V, K20T, E35D, M36I, R41K, K45Q, D60E, Q61E, L63P, H69K, V75I, I93LC
 Pt7FDB_Pt7 NFV D30NL33FL10M, V11F, I13V, I15V, K20R, E35D, M36I, R41K, I62V, L63T, H69K, I93LC
 Pt8FDB_Pt8 NFV D30NL33F, N88DT12S, I15V, G16E, L19I, M36L, R41K, L63Q, H69K, L89IC
 Pt9FDB_Pt9 NFV D30NL33F, N88DT12S, I15V, L19I, M36I, R41K, I62V, L63P, H69K, T74A, L89IM, I93LC
von Wyl (2007)41662849EF449918PINAD30NN88DI15V, E35D, M36I, N37K, R41HN, L63P, H69K, A71AV, I85IV, I93LC
Pillay (2008)DR58DR58AY589910NFV D30N T12S, I13V, I15V, L19I, K20R, E35D, M36I, R41K, K45Q, I64V, H69K, L89I, I93LC
 DR1602ZA.DR16AY589877NFV D30NL10F, V32VA, N88DI15IL, G16E, L19I, E35D, M36IV, R41K, Y59YF, Q61E, I62IV, H69K, T74S, L89M, I93L, N98KC
Kandathil (2009)VL06_253VL06_253EU030406PINAD30NN88D, L89VL10M, T12S, I13V, I15V, L19T, K20T, E21D, E35K, M36I, P39A, R41K, K45R, Q61D, L63P, H69K, T74S, V82I, I93LC
Grossman (2014)217217KF135024NFV, LPV52D30N, I54V, V82AL33F, N88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, H69Q, V75I, L89I, I93LC
 160160KF134989SQV, LPV52D30NN88DT12V, L19I, K20I, M36I, R41K, K45R, L63T, H69K, A71V, I93LC