<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation K20M
Rx PI-naive
IncludeMixtures No
References 20
Patients 47
Isolates 48
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Hoelscher (2001)97TZ0697TZ06AF361876None   T12S, I15V, G16E, L19I, K20M, E35D, M36I, R41K, L63V, H69K, T74S, V77I, L89M, I93LC
Bellocchi (2005)157MC157GU199582None   T12TA, I15V, L19V, K20M, M36I, P39Q, R41K, R57RK, H69K, L89M, I93LC
Rousseau (2006)Pt903PS017MB1DQ351224None   T12S, I15V, L19T, K20M, E35D, M36I, R41K, D60E, L63P, H69K, L89M, I93LC
 03ZASK212B03SK212BDQ978981None   T12S, I15V, L19T, K20M, M36I, R41K, L63I, H69K, L89M, I93LC
Jacobs (2008)18141814EF602243None   T12S, I15V, L19T, K20M, M36I, R41K, H69K, L89M, I93LC
Matthews (2008)PS017PS017FJ199599None   T12S, I15V, L19T, K20M, E35D, M36I, R41K, D60E, L63P, H69K, L89M, I93LC
Ayouba (2009)26582658HALDPRGQ351994None   T12S, I15V, K20M, M36I, R41K, L63P, H69K, L89M, I93LC
Bartolo (2009)LFA1501AOLFA15EU068265None   T12S, I15V, G16E, L19I, K20M, M36L, N37S, L63N, H69K, L89I, I93LC
 HM18001AOHM180EU068320None   T12S, I15V, G16E, L19I, K20M, M36IL, N37S, L63N, H69K, L89I, I93LC
Hosseinipour (2009)87608760GQ228214None   T12S, I15V, L19I, K20M, E35D, M36I, L63P, H69K, V82I, L89M, I93LC
Wallis (2009)23354852335485 None   T12S, I15V, L19I, K20M, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93LC
 22804152280415 None   T12S, I15V, L19I, K20M, M36I, N37T, L63V, H69K, T74S, L89M, I93LC
Gonzalez (2010)MO_1MO_1GQ433872None   T12A, I15V, L19I, K20M, E35N, M36I, N37D, R41K, L63V, H69K, T74S, L89MC
Papathanasopoulos (2010)1692306ZA16923GU253416None   T12S, I15V, G16E, L19T, K20M, E35D, M36I, I62V, L63A, H69K, A71T, I93LC
Wright (2010)113SK113HM593120None   T12TA, I13IV, I15V, G16E, L19I, K20M, M36I, R41K, D60E, G68GE, H69K, L89IM, T91TI, I93L, L97IC
Hamers (2011)300482CP076300482HM119901None   T12S, I15V, L19IR, K20M, M36I, R41K, L63V, H69K, L89M, I93LC
 300558CP076300558HM119967None   T12S, I15V, G16E, L19I, K20M, E35D, M36I, R41K, L63H, H69K, L89M, I93LC
 302395CP076302395HM120103None   T12S, I15V, L19T, K20M, M36I, R41K, L63V, H69K, T74S, L89M, I93LC
 CP076301498CP076301498HQ994451None  V11VIL10M, T12S, I15V, G16E, L19I, K20M, E35D, M36I, R41K, L63IV, H69K, L89M, I93LC
 CP076302166CP076302166HQ994518None   T12S, K14R, I15V, L19IT, K20M, N37S, R57K, I62V, L63S, H69K, L89M, I93LC
 CP076301100CP076301100HQ994782None   T12TS, K14R, I15V, L19T, K20M, E35D, M36I, R41K, H69K, T74A, L89M, I93LC
 CP763A03367CP763A03367HQ994903None   T12S, I15V, G16E, L19I, K20M, E35D, M36I, R41K, K45KR, H69K, T74A, L89M, I93LC
Nwobegahay (2011)08MB47ZA08MB47ZAGU188829None   T12S, G16E, L19I, K20M, E35D, M36I, R41K, D60E, H69K, L89M, I93LC
van Zyl (2011)A142A142JN638086None   L10M, T12S, I15V, L19V, K20M, E35D, M36I, P39Q, R41K, L63V, H69K, L89M, I93LC
Iweriebor (2012)07V10ZA07V10ZAGU201824None   I15V, L19T, K20M, E35D, M36I, R41K, D60E, L63P, H69K, L89M, I93LC
Manak (2012)08_LH0608_LH06JN687634None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
 08_LH0408_LH04JN687632None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
 08_LH0708_LH07JN687635None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
 08_LH0508_LH05JN687633None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
 08_LH0908_LH09JN687637None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
 08_LH0108_LH01JN687629None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
 08_LH0808_LH08JN687636None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
 08_LH0308_LH03JN687631None   T12S, I13V, K14R, G17D, L19I, K20M, M36I, N37S, L63P, H69K, L89M, I93LC
 08_LH0208_LH02JN687630None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
 08_LH1008_LH10JN687638None   T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93LC
Hawke (2013)2991463 H2991463 HKC238110None   L19I, K20M, M36I, N37T, R41K, R57K, L63H, H69K, I93LC
 2991464 H2991464 HKC238111None   G16GE, L19IT, K20M, M36I, N37NT, R41RK, R57K, L63H, I64IV, H69KQ, I72IT, I93LC
Van Zyl (2013)858428KC424055None   K14R, I15V, L19I, K20M, M36I, R41RK, H69K, I93LC
 12501210KC422963None   I15V, G16E, L19T, K20M, E34A, M36I, R41K, L63S, H69K, I72M, V77I, I93LC
  2691KC423789None   I15V, G16E, L19T, K20M, E34AT, M36I, R41K, L63S, H69K, I72M, V77I, I93LC
 14671741KC423371None   L10M, I15V, L19T, K20M, E35D, M36I, R41K, Q61H, H69K, L89M, I93LC
 5871590KC423252None   L5LF, T12S, K14T, G16E, L19T, K20M, M36I, L63V, H69K, T74S, L89M, I93LC
 7251493KC423183None   I15V, L19V, K20M, E35D, M36I, R41K, H69K, T74S, L89M, I93LC
 98981KC424288None   T12S, L19I, K20M, E35G, M36I, R41N, L63MV, H69K, L89M, I93LC
 2381042KC422828None   T12S, I15V, L19I, K20M, E35D, M36I, R41K, L63P, H69K, T74S, L89M, I93LC
 288447KC424066None   T12S, I13V, I15V, L19I, K20M, E34G, M36I, R41K, D60E, L63P, H69K, V82I, L89M, I93LC
 5692049KC423585None   T12S, I15IV, L19V, K20M, E35D, M36I, R41K, L63AITV, I64IM, H69K, K70R, I72IV, T74S, L89M, I93LC
Bartolo (2014)09AOHDP10209AOHDP102KF853754None   T12S, K14KE, I15V, G16E, L19I, K20M, E34A, M36I, P39PS, R41K, L63T, H69K, K70R, L89M, I93LC