<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L10Y
Rx >= 1 PI
IncludeMixtures No
References 4
Patients 12
Isolates 13
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK1447UK1447AY900803IDV, SQV, RTV83G48GA, I54V, V82A, I84V, L90ML23LI, K43KTL10Y, I15V, M36I, R41K, I62V, L63V, H69K, A71V, T74S, L89LM, I93LC
Sen (2007)T093NPT93EF186929RTV, IDV M46I, I54L, L90ML23LI, G73STL10Y, T12S, L19T, K20I, L24LF, R41K, K45KR, K55KR, L63P, H69K, A71V, I72IM, V77I, I93LC
  NPT93-PLEF186978RTV, IDV M46I, I54IL, L90MG73STL10Y, T12S, L19T, K20I, L24F, R41K, K45R, K55R, L63P, H69K, A71V, V77I, I93LC
Saravanan (2013)YRG86YRG86KC016281PINAM46I L10Y, T12S, I13V, I15V, L19I, E34EQ, E35D, M36I, N37D, R41K, K45KR, L63P, H69K, T74A, L89T, I93LC
Diaz (2015)RenG17053RenG17053KT748081PINAI50L, L90ML33IL10Y, I13IV, I15V, K20T, E34EQ, E35N, M36I, N37E, R41N, K45R, D60N, I62IV, L63LP, C67CF, G68GE, H69KR, A71I, L89I, I93LC
 RenG17048RenG17048KT748076PINAM46I, I54L, L90ML33F, Q58E, N88G, L89VL10Y, I13V, I15V, K20T, E35D, M36I, N37Q, R41N, K43R, I62V, L63P, H69K, A71V, T74S, Q92K, I93LC
 RenG16715RenG16715KT747743PINAD30N, I54LN88DL10Y, I15V, L19Q, K20T, E35D, M36I, N37K, R41N, L63V, H69K, A71T, L89T, I93LC
 RenG15215RenG15215KT746243PINAM46L, I50IL, I54V, V82AL24I, L33FL10Y, E35D, M36L, N37EK, R41N, R57K, D60E, L63P, H69K, A71AT, L89I, Q92QK, I93LC
 RenG13568RenG13568KT744596PINAM46I, I54V, V82AK43T, T74PL10Y, I15V, L19LI, K20R, E35D, M36I, N37K, R41N, Q61N, I62IV, L63P, H69K, L89T, I93LC
 RenG13278RenG13278KT744306PINAI54IL, I84V, N88SL33F, Q58EL10Y, I13V, I15V, K20R, E35D, M36I, N37K, R41N, K45R, R57K, D60E, Q61E, I62V, L63P, H69K, A71T, L89M, I93LC
 RenG12637RenG12637KT743665PINAM46I, N88SF53LL10Y, I15V, K20T, E35G, M36I, N37D, R41K, L63V, I64V, H69K, T74A, L89M, I93LC
 RenG11780RenG11780KT742808PINAI54IV L10Y, I15V, K20I, E35G, M36I, N37K, R41N, K45R, H69K, A71I, T74S, I85V, L89T, I93LC
 RenG10990RenG10990KT742018PINAI84V L10Y, I13IV, I15V, K20R, E35D, M36I, N37K, R41N, L63P, H69K, A71IV, I85IV, L89T, I93LC