<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L10M
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 18
Isolates 18
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Doualla-Bell (2006)Pt7FDB_Pt7 NFV D30NL33FL10M, V11F, I13V, I15V, K20R, E35D, M36I, R41K, I62V, L63T, H69K, I93LC
Cardoso (2009)3098BRGO3098FJ638445PINA  L10M, I15V, L19T, M36I, N37K, R41N, L63V, H69K, I93LC
Kandathil (2009)VL06_253VL06_253EU030406PINAD30NN88D, L89VL10M, T12S, I13V, I15V, L19T, K20T, E21D, E35K, M36I, P39A, R41K, K45R, Q61D, L63P, H69K, T74S, V82I, I93LC
Alcantara (2013)BRGO4066BRGO4066JN114160LPV   L10M, I15V, L19I, N37K, R41N, H69K, L89M, I93LC
Van Zyl (2013)324309.ZA.GT834KC424338LPV   L10M, I15V, L19M, E35D, R41K, L63V, H69K, L89M, I93LC
 73209.ZA.WC060KC422859LPV   L10M, K14N, L19I, M36I, R41K, L63V, H69K, L89M, I93LC
 279009.ZA.GT825KC424327LPV   L10M, T12S, I15IV, G16E, L19I, K20KR, M36I, P39S, R41K, D60E, H69K, L89M, I93LC
 218910.ZA.GT1096KC422944LPV   L10M, T12S, I15V, L19IT, M36I, R41K, L63LP, H69K, T74AS, L89M, I93LC
 266010.ZA.GT1324KC423142LPV   L10M, I15V, M36I, R41K, L63V, H69K, L89M, I93LC
Diaz (2015)RenG17227RenG17227KT748255PINA L23IL10M, I13V, K20T, E35N, M36I, N37K, R41N, K45Q, I62V, L63P, H69K, T74K, V82VI, L89I, I93LC
 RenG16176RenG16176KT747204PINA  L10M, K14R, I15V, M36I, N37K, R41N, R57K, H69Q, L89M, I93LC
 RenG14521RenG14521KT745549PINA  L10M, I15V, N37K, R41N, R57RK, L63S, C67E, H69K, V77I, L89M, I93LC
 RenG15422RenG15422KT746450PINA  L10M, I15IV, L19LI, N37K, R41N, L63T, H69K, I93LC
 RenG10491RenG10491KT741519PINAI50L, V82VA, N88S, L90LML33FL10M, I13V, I15IV, K20R, E35D, M36I, N37K, R41N, K45R, H69K, A71V, L89I, I93LC
 RenG11053RenG11053KT742081PINA  L10M, K14KR, I15IV, N37K, R41N, I62IV, L63PT, H69HKNQ, L89M, I93LC
Giandhari (2015)50792006_ZA_5079FKP056179RTV39  L10M, T12S, I15V, L19I, N37K, R41I, L63T, H69K, K70RC
Rossouw (2015)RP069RP069KT032019PINA  L10M, L19T, M36I, N37E, R57K, H69K, I72V, L89M, I93LC
 RP031RP031KT032004LPV102  L10M, T12S, I15V, L19I, N37S, R41K, D60DY, L63V, I64L, H69K, L89M, I93LC