<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype C
Gene PR
Mutation L10I
Rx >= 1 PI
IncludeMixtures No
References 25
Patients 117
Isolates 133
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Kantor (2002)TCDD-30TCDD-30_1AY090856NFV, IDV14I54FLL33FL10I, T12S, I15V, L19I, E34D, M36I, R41K, Q58QP, D60E, L63P, H69K, T74E, P79PL, I85V, L89M, I93LC
Johnston (2003)TC-71TC-71 IDV52G48V, I54T, V82A L10I, I15V, L19I, K20R, E35D, M36I, R41K, L63V, H69K, A71V, T74S, L89M, I93LC
Weber (2003)85H610185H-12AY140821RTV13  L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69K, T74S, V77I, L89M, I93LC
  610185H-48AY140823RTV48I54V, V82A L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69R, T74S, V77I, L89M, I93LC
Grossman (2004)IL201IL201aAY529564IDV16  L10I, T12S, I15V, L19T, M36I, R41K, L63P, I64L, H69K, K70KE, L89M, I93LC
  IL201bAY529565IDV55  W6S, L10I, T12S, I15V, L19T, M36I, R41K, L63X, I64IL, H69KC
  IL201cAY529566IDV83  L10I, T12S, I15V, L19T, M36I, L63P, I64L, H69K, L89T, I93LC
 IL217IL217AY529576NFV104D30NN88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, I64IV, H69Q, L89IM, I93LC
 IL266IL266AY529621SQV, RTV, IDV, NFV180I54IL, I84V, L90MT74TPR8RG, L10I, I15V, K20KI, E35EG, M36I, R41RK, L63P, H69K, A71V, L89M, Q92QR, I93LC
 IL287IL287AY529620SQV, RTV, IDV, NFV184I84V, L90M L5LI, L10I, T12S, I15V, L19I, E35D, M36I, R41K, L63T, H69K, A71V, T74S, I93LC
Montes (2004)MB_patCOU02_COUL707AJ577870SQV, RTV, IDV, NFV221L90MG73SL10I, T12S, I15V, K20T, M36I, R41K, L63P, H69K, A71V, I93LC
Snoeck (2004)BE59BE59AY900757SQV, IDV, RTV, NFV217G48V, I54A, V82AL33F, K43KTL10I, I13V, I15V, L19I, M36L, N37EQ, L38M, I62V, L63V, H69K, I72V, T74S, L89LI, I93LC
Non-B Workgroup (2005)UK186bUK186bAY900763SQV, RTV183I84V, L90MV11VI, G73GSL10I, I15V, G16E, L19I, R41K, L63H, H69K, A71V, V77I, I93LC
 UK955UK955AY900786SQV, RTV, IDV137I54V, I84V, L90MG73S, L89VL10I, I15V, L19I, K20X, E35D, M36I, R41K, D60E, I62IV, L63P, H69K, A71V, I85V, I93LC
 IL257IL257AY900818IDV, RTV110V82A L10I, I15V, L19I, D29DV, M36I, R41K, L63P, H69K, I85V, I93LC
 TK1020TK1020 SQV, RTV, IDV211I54V, V82C, L90MF53LL10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, K55H, L63P, H69K, T74A, L89M, I93LC
  TK1020a SQV, RTV, IDV, LPV229M46L, I54V, V82C, L90ML23I, F53LL10I, I15V, L19I, K20R, E35D, M36I, N37D, K55H, L63P, H69K, T74A, L89M, I93LC
  TK1020b SQV, RTV, IDV, LPV392M46I, I47V, I54V, V82C, L90ML23I, K43T, F53LL10I, I15V, L19I, K20R, E35D, M36I, N37D, R41RK, K55H, I62V, L63P, H69K, T74E, L89M, I93LC
 TK2023TK2023 RTV, IDV, SQV173  L10I, I15V, L19I, M36I, R41K, L63V, H69K, T74S, V75I, L89M, I93LC
 TK3015TK3015 SQV, IDV204I54V, V82A, L90MK43TL10I, T12S, I15V, L19I, K20I, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, I93LC
  TK3015c SQV, IDV, LPV, RTV, TPV375I54V, V82T, I84IV, L90MK43TL10I, T12S, I15V, L19I, K20IR, E35D, M36I, R41K, D60E, Q61E, L63P, H69K, A71V, I85V, L89LM, I93LC
 TK3019TK3019 SQV, NFV, RTV143I54V, I84IV, L90MV11VI, G73SL10I, I13V, I15V, L19I, K20R, E35D, M36I, R41K, K45R, I62V, L63P, H69T, A71V, I72L, I93LC
 TK3035TK3035 IDV, NFV, RTV202I54A, V82A L10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K45KR, D60E, L63P, H69K, A71V, L89M, I93LC
 TK5007TK5007 IDV, RTV261 G73STL10I, T12S, I15V, L19I, E35D, M36I, N37S, R41K, K45R, I62V, L63P, H69K, I85V, I93LC
 PL3670560970 IDV98V82A, L90LMT74PL10I, T12TS, I15V, L19I, K20KR, M36I, N37NS, R41K, K45R, Q61N, L63S, H69K, I72V, L89M, I93LC
 PL472558294 Unknown, LPV>4G48V, I54V, V82T, L90MQ58EL10I, I15V, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63P, H69K, A71T, T74S, I85V, L89I, I93LC
 PL833877353 IDV, RTV304I54V, V82A L10I, I13IV, I15V, L19I, M36L, R41K, I62V, L63P, I64V, H69K, L89M, I93L, C95FC
Weber (2005)F16446F16446AY677447SQV, NFV, APV, LPV208M46I, I54V, I84V, L90M L10I, T12S, L19I, K20M, M36I, R41K, D60E, L63P, H69K, L89M, I93LC
 F30356F30356AY677479Unknown, NFV>201I54V, V82A, L90M L10I, T12S, I15V, L19T, K20R, E35D, M36I, N37H, P39PS, R41K, K45R, L63P, H69KQ, A71I, I93LC
Baxter (2006)12-10071007-30519DQ875953PINAM46L, I54IV, V82A, L90ML33F, K43KTL10I, I15V, L19T, K20R, E35D, M36I, R41K, Q61E, I62IV, L63P, H69K, T74S, L89M, I93LC
 12-17161716-30421DQ876854PINAM46L, I54V, V82A, I84VL24I, L33F, K43TL10I, I15V, K20R, E35D, M36I, N37ND, R41K, I62V, L63T, H69K, T74S, L89M, I93LC
 12-30823082-30430DQ877155PINAM46I, I84V, L90MG73SL10I, T12S, I13N, I15V, L19I, M36I, R41RK, Q61H, L63P, H69K, A71V, I72L, I93LC
 12-31023102-30610DQ877250PINAL90ML23I, L33F, F53L, Q58EL10I, T12P, I15V, G16E, L19V, K20R, E35D, M36I, N37T, I62V, L63T, H69K, T74A, V82I, I85V, L89M, I93LC
 48-12291229-30428DQ877762PINAM46I, I54A, V82F, L90M L10I, T12S, I13V, Q18R, L19I, K20I, E34EQ, E35E_PSDGNS, M36L, I62V, L63P, H69K, T74A, V77I, L89M, I93LC
 48-30583058-30401DQ877970PINAI54L, V82A, L90ML33F, K43KTL10I, L19I, K20R, E35D, M36I, N37D, R41K, I62V, L63P, H69K, T74S, L89M, I93LC
 48-41344134-30317DQ878365PINAG48V, I54V, V82A, I84VL33F, K43TL10I, I15V, G16E, L19I, K20V, E35DN, M36I, L63C, H69K, T74S, I85V, L89M, I93LC
 48-80568056-30930DQ879080PINAV32I, I47AL33F, Q58EL10I, T12S, I15V, L19I, K20T, M36I, D60E, L63P, H69K, T74A, V82I, I85V, L89M, I93LC
Sanabani (2006)04BR01304BR013AY727522PINAM46I, G48V, V82AL24IL10I, K20R, M36I, N37E, R41K, K55R, I62V, L63P, H69K, T74A, L89M, I93LC
Sen (2007)T076NPT76-PLEF186980NFV, RTV M46LT74PL10I, T12S, L19I, K20R, M36I, K55N, L63P, H69K, A71V, L89M, I93LC
 T002NPT2EF186926RTV, IDV M46I, I54V, V82VAL24IL10I, T12S, I15V, L19I, M36L, N37S, R41K, Q61H, L63P, H69K, L89M, I93LC
  NPT2-PLEF186983RTV, IDV M46I, I54V, V82AL24IL10I, T12S, I15V, L19I, M36L, N37S, R41K, Q61H, L63P, H69K, A71AV, L89M, I93LC
Pillay (2008)DR44DR44AY589899RTV M46I, I54V, V82A L10I, I15V, L19I, K20R, M36I, N37S, H69K, L89M, I93LC
Kandathil (2009)VL07_103VL07_103EU781835PINAM46I, I54V, V82AL24IL10I, T12S, I15V, L19T, M36I, R41K, L63P, H69K, L89M, I93LC
Kassaye (2009)TCDD-30TC30_2003FJ445708NFV, IDV99I54V, I84V L10I, T12A, I15V, L19I, K20KR, E35D, M36I, R41K, L63P, H69Q, L89M, I93LC
Dau (2010)06552A06552AGU581760PINAM46I, I54V, L76V, V82A L10I, I13V, G16GE, L19I, K20R, M36I, N37ND, R41K, Q61N, L63PS, H69K, T74S, L89M, I93LC
Knops (2010)ID2137ID2137-GT1GU271172IDV, LPV V32I, I47A, V82A L10I, T12S, I15V, L19AP, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93LC
  ID2137-GT2GU271173IDV, LPV, DRV, RTV33V32I, I54L, L76V, V82AL89VL5F, L10I, T12S, I15V, L19T, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93LC
Malan DR (2010)7DMG_7a ATV48  L10I, I13V, G16GE, L19T, K20R, M36I, R41K, L63AITV, I64IM, E65D, H69K, T74TA, L89M, I93LC
Green (2011)707PKE19F707PKE19FHM623509RTV, LPV131M46I, I54V, L76V, V82AQ58EL10I, T12S, I15V, L19T, K20R, E35D, M36I, R41K, I62V, L63P, H69K, L89M, I93LC
Barber (2012)6599465994JQ361682LPV M46MI, I54V, V82A L10I, T12S, I15V, L19V, M36I, R41K, K45KR, L63P, H69K, T74S, I93LC
Kouri (2012)CU310-10CU310-10JQ585380PINAL90M L10I, I13IV, E35D, N37S, R41K, L63P, H69K, L89M, I93LC
 CU2104-09CU2104-09JQ585341PINAG48GV, I54MV, I84V, L90LML33F, Q58QE, T74PS, N83NDL10I, E34K, E35D, M36I, N37S, R41K, L63LP, G68GE, H69K, A71AV, L89IM, I93LC
 CU1340-10CU1340-10JQ585423PINAM46I, I54AT, V82A, I84IVL24I, L33F, K43TL10I, I13V, I15V, K20R, E35D, M36I, N37S, R41K, L63P, H69K, A71AV, T74TA, L89M, I93LC
Van Zyl (2013)13341229KC422979LPV26  L10I, T12S, I15V, L19T, K20R, E35N, M36I, R41K, H69Q, L89M, I93LC
  1657KC423304LPV26  L10I, T12S, I15V, L19T, K20R, E35N, M36I, R41K, H69Q, L89M, I93LC
 1177240KC423694LPV26  L10I, I15V, L19I, M36I, P39PQ, R41K, L63T, H69Q, L89M, I93LC
 751548KC424133LPV26M46I, I50V, I54V, V82AL23IL10I, T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61HN, L63N, H69K, A71V, L89M, I93LC
  1563KC423234LPV26M46I, I50V, I54V, V82AL23IL10I, T12S, I15V, G16E, L19I, K20R, E35D, M36I, R41K, Q61HN, L63H, H69K, A71V, I72IM, L89M, I93LC
 582996KC424424LPV26M46I, I54V, L76V, V82A L10I, T12S, L19I, K20R, M36I, R41K, K55R, D60E, L63P, H69K, A71V, L89M, I93LC
  1287KC423030LPV78M46I, I54V, L76V, V82A L10I, T12S, L19I, K20R, M36I, R41K, K55R, D60E, I62V, L63P, H69K, A71V, L89M, I93LC
 905569KC424143LPV26  L10I, K14S, I15V, L19I, M36I, R41K, L63T, I64M, H69K, I72V, L89M, I93LC
 4502121KC423634LPV104 V11IL10I, I13V, G16E, Q18K, L19T, K20R, M36I, R41K, K43I, R57RK, L63T, H69K, L89M, I93LC
 82457KC424144LPV26  L10I, T12S, I15V, L19T, K20R, M36I, R41RK, D60DE, Q61E, I62IV, L63T, E65D, H69K, L89M, I93LC
 12059KC423591LPV26  L10I, T12S, K14KR, I15V, L19D, M36I, R41K, L63V, H69K, T74TA, L89M, I93LC
 16391905KC423504LPV26  L10I, T12S, I15V, L19I, M36I, R41K, L63T, H69Q, I72T, I93LC
 622524KC424116LPV26  L10I, I15V, L19V, E35D, M36I, R41K, L63V, H69K, T74S, L89M, I93LC
 624991KC424420LPV26  L10I, T12S, L19I, M36L, L63P, H69K, K70R, L89M, I93LC
 1823126KC423008LPV26I54V, V82A L10I, T12S, I15V, G16A, L19V, K20R, E35D, M36I, R41K, L63PS, H69K, T74S, L89M, I93LC
 14371338KC423071LPV26  L10I, G16E, L19T, M36I, H69K, L89M, I93LC
 12681155KC422920LPV26  I3V, L10I, L19I, M36I, R41K, L63P, I64L, H69K, I93LC
 152711KC423795LPV26  L10I, K14T, I15V, L19V, M36I, R41K, L63T, E65D, H69K, L89M, I93LC
Grossman (2014)609609KF135112LPV52M46I, I54V, V82A, L90MN83D, L89VL10I, V11L, I13A, K20R, A22V, E35N, M36I, N37D, R41K, I62V, L63P, H69K, A71V, I93LC
  609 LPV134M46I, I54V, V82A, L90MG73S, N83D, L89VL10I, V11L, I13V, K20R, A22V, E35N, M36I, N37D, R41K, K55R, I62V, L63P, H69K, A71V, T91S, I93LC
  609 LPV292M46I, I54V, V82A, L90MG73GS, N83D, L89VL10I, V11L, I13AV, K20R, A22V, E35N, M36I, N37D, R41K, K55R, R57RK, I62V, L63P, H69K, A71IV, T91S, I93LC
 16281628KF134991LPV52 V11IR8T, P9T, L10I, I15V, L19I, M36I, R41K, L63T, H69K, T74S, L89M, I93LC
 285285KF135040IDV, LPV52  L10I, I13V, K14R, I15V, M36I, N37D, R41K, L63V, E65D, H69K, T74S, L89M, I93LC
 183183KF135005NFV, LPV52M46I, I54V, V82F, L90M L10I, I13V, I15V, L19T, K20T, E35N, M36I, R41K, K45R, H69K, A71T, T74S, V77I, L89I, I93L, C95YC
 217217KF135024NFV, LPV52D30N, I54V, V82AL33F, N88DL10I, I13V, K14R, I15V, K20R, E35D, M36I, R41K, L63Q, H69Q, V75I, L89I, I93LC
  217KF135025NFV, LPV273M46I, I50V, I54V, V82A, L90ML33FL10I, I13V, K14R, I15V, K20R, E35D, M36I, N37DE, R41K, K55R, L63E, G68GE, H69Q, A71AV, L89I, I93LC
 201201KF135014IDV, LPV52M46IT74PL10I, T12S, I15V, L19T, M36I, R41K, K55R, L63I, H69K, L89M, I93LC
 581581KF135103IDV, LPV52L90M L10I, T12TA, L19I, K20I, E35ED, M36I, R41K, Q61H, L63P, I64L, H69K, A71V, T74S, I85V, L89M, I93LC
  581KF135104IDV, LPV187L90M L10I, L19I, K20I, E35D, M36I, R41K, Q61H, L63P, I64L, H69K, A71V, T74S, I85V, L89M, I93LC
 789789KF135144NFV, RTV, IDV, LPV52I54IV, V82A, I84IV L10I, T12S, I15V, K20M, E34K, M36I, R41K, L63V, H69K, T74S, L89M, I93LC
 464464 NFV, IDV, LPV52V32I, I47V, I54MN83DL10I, M36I, R41K, I62V, L63V, T74S, V82I, I85V, L89I, I93LC
Diaz (2015)RenG16635RenG16635KT747663PINA  L10I, K14R, G16GE, N37K, R41N, D60E, Q61E, I62V, L63P, C67CS, H69K, V77I, L89M, I93LC
 RenG17127RenG17127KT748155PINA  L10I, I15V, L19I, M36I, N37K, R41N, Q61E, L63V, H69K, L89M, I93LC
 RenG16936RenG16936KT747964PINA  L10I, G16E, N37K, R41IT, R57K, D60E, L63T, H69K, L89M, I93LC
 RenG16898RenG16898KT747926PINA  L10I, I13V, M36I, N37K, R41N, I62V, L63V, C67Y, H69K, T74S, L89MC
 RenG15743RenG15743KT746771PINAM46I, I50L, V82AL24I, L33F, K43TL10I, I13V, K14KR, I15V, M36L, N37K, R41N, K55R, D60DEKN, I62V, L63P, H69K, A71V, T74S, I93LC
 RenG17418RenG17418KT748446PINAM46I, I54V, V82F, L90M L10I, V11L, I13V, I15V, K20IT, E35G, M36I, N37K, P39Q, R41N, F53Y, L63P, I64IV, H69K, T74S, L89I, I93LC
 RenG16582RenG16582KT747610PINA  L10I, I15V, L19I, M36I, N37K, R41N, K43KR, Q61E, L63V, H69K, L89M, I93LC
 RenG16825RenG16825KT747853PINA  L10I, M36I, N37K, R41N, L63T, H69K, L89M, I93L, N98IC
 RenG17259RenG17259KT748287PINAI54V, V82T L10I, I15V, K20R, M36I, N37K, R41N, I62V, L63P, H69K, A71AV, T74S, I85V, L89IM, I93LC
 RenG14788RenG14788KT745816PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, K20R, E35D, M36I, N37K, R41Y, R57RK, Q61N, L63P, H69K, A71V, L89M, I93LC
 RenG15086RenG15086KT746114PINA  L10I, K14GR, I15V, M36I, N37K, R41N, L63V, H69K, L89M, I93LC
 RenG13652RenG13652KT744680PINA  L10I, K20R, M36I, N37K, R41N, L63AT, H69K, L89M, I93LC
 RenG13840RenG13840KT744868PINAI54A, V82M, L90MQ58EL10I, I15V, G16A, K20R, E35D, M36I, R41K, I62IV, L63P, H69K, A71IV, I72IT, I85V, L89M, Q92QK, I93LC
 RenG14354RenG14354KT745382PINA  L10I, K14R, G16E, N37K, R41IN, R57RK, H69K, L89M, I93LC
 RenG14451RenG14451KT745479PINA  L10I, L19I, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG14721RenG14721KT745749PINA  W6G, L10I, M36I, N37E, R41N, D60N, L63T, H69K, L89M, I93LC
 RenG14330RenG14330KT745358PINA  L10I, I13V, I15V, K20R, M36I, N37K, R41N, H69K, I72V, L89I, I93LC
 RenG14113RenG14113KT745141PINAG48V, I50V, I54V, V82AL33IL10I, I13V, L19IV, E35D, M36I, N37R, R41N, Q61E, I62V, L63P, H69K, T74S, I85V, L89IC
 RenG14949RenG14949KT745977PINA T74PL10I, T12S, I15V, L19I, M36I, N37K, R41N, D60DE, L63PT, H69K, L89M, I93LC
 RenG13882RenG13882KT744910PINAL90M L10I, V11F, I15V, L19I, K20I, L33V, R41K, K45R, L63P, H69K, A71I, L89T, I93LC
 RenG15500RenG15500KT746528PINAM46I, I47IV, I54V, V82F, L90ML23I, L33LI, F53FL, Q58EL10I, I13V, K14KR, K20R, E35D, M36I, N37K, R41N, K55KR, I62IV, L63P, H69K, L89I, Q92QK, I93LC
 RenG14834RenG14834KT745862PINAM46I, I54V, L76V, V82F, L90ML33FL10I, I13V, I15IV, K20R, E35D, M36I, N37K, R41N, Q61N, L63P, G68GE, H69K, K70KR, A71V, L89IM, I93LC
 RenG12983RenG12983KT744011PINAI54V, V82A, L90M L10I, K20R, E35D, M36I, N37K, R41P, Q61QK, L63P, H69K, A71V, I72VC
 RenG12315RenG12315KT743343PINA  L10I, I15V, M36I, N37K, R41N, L63AITV, H69K, L89M, I93LC
 RenG12407RenG12407KT743435PINA  L10I, I13V, K20R, M36I, N37E, R41N, Q61K, L63I, H69K, T74K, L89M, I93LC
 RenG13284RenG13284KT744312PINA  L10I, I13V, I15V, G16E, M36T, N37K, R41N, L63T, H69K, L89M, I93LC
 RenG12354RenG12354KT743382PINAM46I, I54V, V82A, L90ML33LI, K43KT, G73SL10I, I15V, L19LP, K20KI, A22AV, E35DN, M36I, N37K, P39PQ, R41N, K45KR, I62V, L63P, C67F, H69K, A71IV, I72L, I85V, I93ILC
 RenG13225RenG13225KT744253PINAL90LML23LIL10I, I15IV, K20KR, E35ED, M36I, N37K, R41N, K45KR, I62IV, L63V, I64IV, H69K, T74TS, L89M, I93LC
 RenG11645RenG11645KT742673PINA  L10I, K14KR, E35D, M36I, N37K, R41N, H69K, L89M, I93LC
 RenG11482RenG11482KT742510PINA  L10I, I15V, M36I, N37K, R41N, H69K, L89M, I93LC
 RenG11520RenG11520KT742548PINAI54IV, V82VA, L90LML23LI, G73GS, L89MVL10I, I15V, G16GW, L19LP, K20KIM, E35D, M36I, N37K, R41N, K45KR, K55KR, I62IV, L63LP, H69K, A71AT, I85IV, I93LC
 RenG11203RenG11203KT742231PINA  L10I, K14R, I15V, M36IT, N37K, R41N, H69K, L89M, I93LC
 RenG10739RenG10739KT741767PINA  L10I, E35ED, M36I, N37K, R41N, L63V, H69K, L89IM, I93LC
 RenG10428RenG10428KT741456PINA  L10I, I13IV, I15IV, K20R, M36I, N37K, R41N, R57K, L63V, H69K, T74S, L89M, I93LC
 RenG10331RenG10331KT741359PINAM46I, I50L, V82AT74PL10I, I15V, L19I, K20R, M36I, N37K, R41N, I62IV, L63V, H69K, A71V, L89M, I93LC
 RenG11076RenG11076KT742104PINAI54V, V82A, L90ML23I, G73S, L89VL10I, I15V, G16GW, L19LP, K20IM, E35D, M36I, N37K, R41N, K45R, K55KR, I62V, L63P, H69K, A71T, I85V, I93LC
 RenG11471RenG11471KT742499PINAI54V, V82AK43T, T74PL10I, I15V, L19LI, K20R, E35D, M36I, N37K, R41INS, R57K, I62V, L63V, I64V, H69K, A71V, L89M, I93LC
 RenG10378RenG10378KT741406PINA  L10I, I15V, M36I, N37K, R41N, L63I, H69K, L89M, I93LC
 RenG10661RenG10661KT741689PINAM46I, I54V, V82A, L90ML33F, Q58E, G73SL10I, I13V, L19I, K20R, E35D, M36I, N37K, R41K, K55N, L63P, H69K, A71T, T74S, Q92K, I93LC
 RenG10978RenG10978KT742006PINAI54V, V82AL33F, T74PL10I, I13V, G16E, K20R, M36I, N37K, R41N, L63T, H69Q, L89M, I93LC
 RenG10474RenG10474KT741502PINAG48S, I54V, V82F, L90ML33F, K43T, T74P, N83DL10I, I13V, K14R, I15V, E35D, M36L, N37K, R41IN, Q61N, I62V, C67CR, H69Q, L89I, I93LC
 RenG10982RenG10982KT742010PINAM46I, I50V, I54V, V82A, L90MV11I, L33F, K43T, T74PL10I, I13V, I15V, K20R, E35D, M36I, N37K, R41N, I62IV, L63P, H69R, A71V, L89LM, I93LC
 RenG10394RenG10394KT741422PINAG48V, I54T, V82A L10I, I15V, K20R, E35D, M36I, N37K, R41N, Q61H, L63V, H69K, A71V, I72IR, T74S, I85V, L89I, I93LC
 RenG10631RenG10631KT741659PINAM46L, I54V, V82A, I84VV11I, L24I, K43TL10I, T12E, I13V, L19I, K20I, M36I, Q61N, L63T, I64V, H69K, A71V, I72IV, T74S, I93LC
Novitsky (2015)bcpp_203bcpp_203KR860688PINA  L10I, G16E, L19V, M36I, N37D, L63T, H69K, L89M, I93LC
Rossouw (2015)RP038RP038KT032009LPV89M46MI, I50V, I54V, V82A L10I, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, Q61D, I66L, H69K, A71AV, L89M, I93LC
 RP154RP154KT032055LPV, RTV228M46I, I54V, V82AQ58EL10I, T12S, I15V, L19I, K20R, E35D, M36I, R41K, K55KR, L63LP, H69K, K70R, L89IM, I93LC
 RP104RP104KT032036LPV124M46I, I50V, I54V, V82A L10I, T12S, I15V, L19V, K20R, T31TI, E35D, M36I, R41K, L63P, H69K, K70R, A71V, V77I, L89M, I93LC
 RP045RP045KT032012LPV133M46I, I54V, L76V, V82AQ58EL10I, I15V, L19I, K20R, E35D, M36I, R41K, D60E, Q61D, L63P, C67E, H69K, L89MC