Protease Inhibitors

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Protease Inhibitors

Subtype	B
Gene	PR
Mutation	L63T
Rx	>= 1 PI
IncludeMixtures	No

References	58
Patients	231
Isolates	275

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	Wks	PIMajorDRMs	PIMinorDRMs	OtherMut	Subtype
Schapiro (1996)	EV3	EV3_W0	AF013867	SQV	84			T12P, K14R, R41K, L63T, I64L, V77I, I93L	B
	EV1	EV1_W24	AF013876	SQV	24		Q58E	L10I, E35D, R41K, I62V, L63T, A71T, I93L	B
Craig (1998)	Craig-pt1	1W24		SQV	24		Q58E	Q18R, M36I, L63T, A71T	B
Deeks (1999)	SD-16	SD-16	AF124552	RTV	52	V82F	V11I	L10I, I13V, G16E, E35D, N37S, L63T, I64V, C67Y, V77I	B
Gatanaga (1999)	Gat-NR7	agaNR700	AB020922	IDV	32			Q2H, K14R, I15V, L19I, R41K, Q61L, L63T, I93L	B
Murphy (1999)	ACTG347_0040	040_PR_w11		APV	11			N37S, L63T, H69Y, K70KE, N98D	B
	ACTG347_0043	043_PR_w20		APV	20	I54IL		L10I, L63T, I93IL	B
Zolopa (1999)	CA1113	CA2499	AF085114	SQV, NFV	53	D30N	Q58E	T12M, K20R, E35D, M36I, R57K, I62V, L63T, I64V	B
Atkinson (2000)	BA5	BA5	AF247879	NFV	7	D30N, M46I		N37NS, R41RK, L63T, E65D, K70KR	B
Bacheler (2000)	LB3-P21	P21-8		IDV	8			L63T, I72V	B
		P21-12		IDV	12			L63T, I72V	B
		P21-16		IDV	16			L63T, I72V	B
		P21-33		IDV	33	M46L, V82A		L63T, I72V	B
		P21-45		IDV	45	M46L, V82A		L10I, L63T, I72V	B
		P21-70		IDV	70	M46L, V82A	L24I	L10I, I15V, L63T, I72V	B
		P21-96		IDV	96	M46L, I54V, V82A		L10I, L63T, I72V	B
	LB3-P44	P44-1		IDV	1			V56A, L63T, I64M, I72V	B
	LB4-P101	P101-72		IDV	52	M46I, V82F	L24I	L10I, M36I, I62V, L63T, I93L	B
	LB4-P102	P102-42		IDV	12	M46L		L10I, N37H, R41K, L63T, I64V, I93L	B
Balotta (2000)	CB-136	CB-136	AF252005	RTV, IDV		V82A		N37D, L63T, I64L, I72V, V77I	B
	CB-168	CB-168	AF252030	IDV		M46L, V82A		L10I, N37D, L63T, C67D, V77I, I93IL	B
	CB-210	CB-210	AF252060	RTV		M46I, I54V, V82A		M36I, Q61H, L63T, H69K, I72T	B
Baxter (2000)	GART-NG71	GART-71		PI, IDV	NA	M46I, V82F		L10I, I13V, I15V, M36I, N37S, R41K, L63T, I72T, I93L	B
	GART-NG109	GART-109		PI, IDV	NA	I54V, V82A	L33I	K20R, M36I, R41K, I62V, L63T, I64V, I85V	B
	GART-NG141	GART-141		PI, NFV	NA	G48V, I54T, V82A		L10I, G16E, K20KM, L63T, A71V, V77I, I93L	B
Masciotra (2000)	SM33	SM33_17	AF221024	PI	NA			E35D, D60E, L63T, T96S	B
Parkin (2000)	SD-16	SD-16_4	AF294559	RTV, SQV, NFV	56	V82F	V11I	L10I, I13V, G16E, E35D, N37S, L63T, I64V, C67Y, V77I	B
Rousseau (2000)	MNR17	MNR714mal	AJ405961	IDV, SQV, RTV, NFV	102	G48V, I54V, V82A		L10I, R41K, L63T, H69Y, A71V, I72T, T74A, V77I, I93L	B
Sevin (2000)	SA-270788c	SA-270788c	AF226133	SQV	73			K14R, N37E, K43R, L63T, I64M, A71V, I72T, I93L	B
	SA-171040c	SA-171040c	AF226114	SQV	90	L90M		N37D, L63T, A71T, V77I, I93L	B
	SA-042298h	SA-042298h	AF226079	SQV	185	L90M		L10LI, K20KT, L38LF, L63T, I64V, T74S, V77I	B
Walter (2000)	HW6	HW6_2	AF288801	IDV, SQV, NFV	16			I13V, N37S, L63T, E65X, V77I, L89M	B
	HW7	HW7_1	AF288802	RTV, IDV		M46I, I54V, V82A		L10I, I15V, R41K, Q61X, I62M, L63T, H69Y, I72T, I93L	B
Bacheler (2001)	DMP003-21	03-21503	AF349328	IDV	72	M46L, V82A	L24I	L10I, I15V, L63T, I72V	B
Caride (2001)	ERRJ04	PROERRJ04	AF165570	SQV, RTV				T12E, L19I, N37C, L63T	B
	ERRJ09	PROERRJ09	AF165575	IDV				L63T, I64L, V77I, G78R, Q92R	B
Cinque (2001)	Pat14	14pla_BL	AF259952	SQV				L10I, I13IV, G16E, L33LV, E35D, N37T, R57K, I62V, L63T, I64V, C67Q, N83Y	B
		14csf_Post	AF266539	SQV, RTV	8		I47IL	L10I, I13V, G16E, L33V, E35D, N37T, R57K, I62V, L63T, I64V, C67Q	B
Delgado (2001)	ED_V15	ED_V15	AY016826	RTV				L10I, I13V, G16E, M36MI, L63T, I93L	B
	ED_V56	ED_V56	AY016867	SQV				T12P, L19I, N37S, L63T, V77I, I93L	B
Eshleman (2001)	A097	AF357779	AF357779	RTV	13			I15IV, G16GE, R41K, L63T, E65D, K70KR, I72V, V77I	B
Gonzales (2001)	CA1283	CA3084	AY030503	IDV	93	V82A		L10I, I62V, L63T, I64L, I93IL	B
	CA1332	CA3346	AY030529	IDV, NFV	68	I84V		L10I, T12P, G16E, L19I, E35D, M36MI, N37D, L63T, C67Y, A71T, I72T, I93L	B
	CA1522	CA4361	AY030641	IDV, NFV	119	M46L, I54V, V82A		I15LV, I62IV, L63T, I66F, I72IT	B
	CA1585	CA4519	AY030684	SQV, NFV, IDV	49			L10I, G16E, E35D, M36I, R57K, L63T, I93L	B
	CA1626	CA4610	AY030714	SQV, IDV	135	I84IV		L10I, L63T, H69Q, A71AV	B
	CA1833	CA4929	AY030743	IDV, NFV	115	D30N, M46L, V82A		L10I, T12S, I13IV, G16GE, L19V, L63T, A71V, I72T, I93IL	B
	CA2249	CA8161	AY030836	RTV, IDV	56			I15V, E35D, N37DE, L63T, I64V	B
	CA3891	CA9641	AY030896	RTV, IDV, NFV	152			L10V, V11VA, I15V, K20R, E35D, M36I, N37D, L63T, I72V	B
	CA3977	CA9548	AY030976	IDV, SQV, RTV, NFV	98	V32I, M46I, I84V		L10V, I15V, G16E, E34N, E35D, N37S, P39PS, R41K, L63T, I72V, V77I	B
	CA4000	CA9612	AY030998	RTV	12	I84V, L90M		N37D, R57K, D60E, I62V, L63T, H69Y, A71V, I72T, V77I, I93L	B
	CA4035	CA9748	AY031030	RTV, NFV, Unknown	>77	D30N	N88D	L10I, E35D, M36V, N37Y, R41K, I62V, L63T, A71V, I72V, I93L	B
	CA4094	CA9797	AY031086	NFV	4			G16GE, D60E, I62V, L63T, E65D, V77I	B
	CA4345	CA10753	AY031208	IDV, NFV, SQV, RTV	148	M46I, G48Q, I54T, V82F, L90M	K43T	L10I, E35D, M36I, N37D, I62V, L63T, I72V, V77I, L89M, I93L	B
	CA4861	CA12042	AY031501	IDV, SQV, NFV	113	M46L, I54V, V82A, L90M		L10I, E35D, N37D, R57K, D60E, I62V, L63T, I64V, A71AV, I93IL	B
	CA5195	CA13203	AY031758	SQV, RTV, NFV	196	I54V, V82F	K43T	L10I, I13V, I15IV, E35D, M36I, N37S, D60E, I62V, L63T, I64V, I72V, V77I	B
	CA5240	CA12915	AY031797	NFV	25	D30N		I13V, I15V, G16E, M36MV, L63T, I64V	B
	CA5248	CA12888	AY031805	NFV	63			L10I, G16GE, L19Q, E35D, N37S, L63T, I93L	B
	CA5249	CA12889	AY031806	IDV, SQV, RTV	37	M46I, I54V, V82A, L90M	F53L	I62V, L63T, A71V, I93L	B
	CA6011	CA14942	AY032254	NFV	20	D30N		N37S, L63T, V77I	B
	CA6496	CA16283	AY032447	NFV, SQV	132		L23LI	I15IV, G17GW, E35D, N37S, R41K, L63T	B
	CA6830	CA17001	AY032562	IDV	57			T12P, M36I, N37T, R41K, Q61N, L63T, I64V, E65D, K70R, I72V, I93L	B
Kempf (2001)	DK-8873	DK-8873		NFV	76	D30N	N88D	L10I, L63T, I64V, E65D, A71V, V77VI	B
		8314_d168		NFV, LPV	100	D30N	N88GD	L10I, L63T, I64V, E65D, A71V	B
Parkin (2001)	NP-D16	NP-D16		Unknown, IDV, SQV, NFV	NA	V82F		L10I, L63T, V77I	B
Servais (2001)	JS17	JS98372	AJ401954	IDV	88			I15V, E34D, E35I, L63T, I64V, I93L	B
Gibb (2002)	DMG46	46_w43		NFV	43			L10I, E35D, L63T, I93L	B
		46_w48		NFV	48		I50IN	L10I, E35D, L63T, I93L	B
Kantor (2002)	EV3	EV3_sqv		SQV	99	G48V, V82A	L23LI	L10I, K14R, A22V, L63T, G68E, A71V, V77I, I93L	B
		EV3_idv	AY047368	SQV, IDV	118	G48V, V82A		L10I, K14R, L63T, G68E, A71V, V77I, I93L	B
	CA1332	CA7959	AY047420	IDV, NFV, SQV, RTV	104	I84V		L10I, T12P, G16E, L19I, E35D, M36MI, N37D, L63T, C67Y, A71T, I72T, I93L	B
	CA5195	CA17528	AY047475	SQV, RTV, NFV	238	M46ML, G48EV, I54V, V82F, L90LM	K43T	W6W*, L10I, I13V, I15V, E35D, M36I, N37S, I62V, L63T, I64V, I72V, V77VI	B
Margot (2002)	MM-371436656	3714366561		PI	NA	M46I, I54V, V82AT		L10I, K14KR, G16E, K20R, E35D, M36I, R41K, K55KR, I62V, L63T, I72V, P79A, L89M, I93L	B
	MM-235036860	2350368601		PI	NA			T12P, K14R, I62V, L63T, A71T, I72E, V77I, I93L	B
	MM-278536682	2785366821		PI	NA			L10V, G16A, N37A, L63T, V77I	B
	MM-287736669	2877366691		PI	NA	I54L, V82F	Q58E	L10I, R41K, L63T, E65D, I72V, V77I	B
Venturi (2002)	GV-1	GV-1.1	AF517253	SQV	44			I62V, L63T, I72M, V77I	B
	GV-7	GV-7.1	AF517259	SQV	24			K14KR, L19V, E21EV, L38LF, I62V, L63T, T74A, V77I	B
	GV-44	GV-44.1	AF517296	NFV	63	D30N		L10I, I13V, I15V, G16E, E35D, M36I, L63T, H69Q, I72IT	B
Gonzales (2003)	CA1833	CA24787	AY305966	IDV, NFV, SQV, RTV, APV	212	M46L, G48V, I54M, V82A, I84V	L33F	L10I, T12S, L19V, L63T, A71V, I72T, I93L	B
Monno (2003)	ML_Pat2	ML_Pat2		PI	NA			N37E, L63T	B
	ML_Pat9	ML_Pat9		PI	NA		G48E	R41K, I62V, L63T, V77I	B
	ML_Pat47	ML_Pat47		PI	NA	M46I		L10V, I13V, I15V, Q18H, K20T, K55R, R57K, L63T, C67D, V77I, I93L	B
Saah (2003)	AS-38	AS-38		NFV	33	M46L	L10F, T74P	T12I, I15V, L19T, L63T, I72V	B
	AS-42	AS-42		NFV	111	L90M	Q58E, G73S	L10I, D60E, I62V, L63T, A71V, T74S, V77I	B
Shafer (2003)	A384_0867	0867b	EF548473	NFV	55	D30N		L10I, I15V, N37D, R41K, D60E, I62V, L63T, V77I, I93L	B
	A384_1575	1575b	EF548635	NFV	13			N37D, L63T, V77I, I93L	B
	A384_1933	1933d		NFV	23			I62IV, L63T, A71V, I72T, V77I, I93L	B
	A384_6200	6200b	EF548681	NFV	4	M46MI		I13V, G16E, E35D, M36I, N37NK, R41K, K45R, L63T, I64V, E65D, I72T, V77I, Q92QK, I93IL	B
	A384_1145	1145b	EF548970	NFV	120	V32VI		W6WR, L10I, E35D, M36MI, D60DE, I62IV, L63T, E65D, A71AV	B
	A384_5951	5951c	EF549359	NFV	10			I62IV, L63T, I64L, V77I	B
Wu (2003)	CA1626	CA8199	AF544508	SQV, IDV	152	I84IV		L10I, N37X, K55KR, L63T, H69Q, A71AV	B
	CA5195	CA21312	AF544582	SQV, RTV, NFV	265	M46L, G48EV, V82F, L90LM	K43T	L10I, I13V, I15V, E34EK, E35D, M36I, N37S, I54X, D60DE, I62V, L63T, I64V, I72V, V77VI	B
Colonno (2004)	RC-009-007-064	007-06411		NFV		D30N	L33F, N88D	K14R, I15V, R41K, D60E, Q61N, L63T	B
Gomez-Carrillo (2004)	98766	98766	AY365581	PI	NA	V82A		L10I, R41K, L63T, K70KT, V77I, I93L	B
	100755	100755	AY365618	PI	NA			L10I, M36I, N37E, L63T, I64L, I72V, I93L	B
	108666	108666	AY365792	PI	NA	M46I, I84V, L90M		L10V, T12K, K20I, E35D, M36I, R41K, L63T, I64V, A71V, V77I, I93L	B
	122425	122425	AY366011	PI	NA			I13V, I15V, R41K, K43R, I62V, L63T, V77I	B
	125287	125287	AY366044	PI	NA			L10V, I13V, L33V, K45R, L63T, I64V	B
	126443	126443	AY366054	PI	NA			T12S, E35D, N37D, K43R, R57K, I62V, L63T, I64V, H69R, A71T, V77I	B
Montes (2004)	MB_patNAT	01_NAT716	AJ577960	IDV, SQV, RTV, NFV, LPV, APV	226	M46L, G48V, I54V, V82A, I84V	Q58E	L10I, K14R, K20R, M36I, L63T, I64V, K70T	B
	MB_patLEJ	02_LEJ703	AJ577932	IDV, RTV	52			R41K, L63T, E65D	B
Mueller (2004)	MSM_pat2	MLpat2_b		PI	NA	M46I, I54V, V82T, I84V, L90M	Q58E	L10I, I15V, L19I, K20R, M36I, R41K, K55R, I62V, L63T, I64V, I72V, T74K, L89M, I93LM	B
		MLpat2_c		PI	NA	M46I, I54V, V82T, I84V, L90M	Q58E	L10I, I15V, L19I, K20R, M36I, R41K, K55R, I62V, L63T, I64V, I72V, T74K, L89M, I93LM	B
Nukoolkarn (2004)	267	267		RTV, IDV		M46I		L63T, I72T, L89M	B
Rhee (2004)	CA14752	CA38174		Unknown, LPV	>12			G16E, M36I, N37D, R57RK, I62V, L63T, A71V, I72T, I93L	B
Garcia-Bujalance (2005)	GBS_13	GBS_13	AY872294	NFV			V11I	T12N, I15V, L19I, L63T, V82I	B
Mo (2005)	9095	9095_d1		PI	NA	M46MI, I54V, V82A	L24LI	L10I, T12P, K14R, G16E, K20KT, M36MI, P39S, K55KR, I62V, L63T, I64IL, G68D, A71V, I93L	B
		9095_d337		PI, LPV	NA	I54V, V82A		L10I, T12P, K14R, G16E, K20T, M36I, P39S, I62V, L63T, G68D, A71V, I93L	B
	9019	9019_d1		PI	NA			I15IV, M36I, L63T, I64IV, E65ED, I72IT	B
		9019_d349		PI, LPV	NA			L10LI, M36MI, L63T, E65ED, I72IT	B
Non-B Workgroup (2005)	PL9219	65471		IDV		V82T	K43T	L10IV, Q18QH, K20R, E35D, M36I, N37D, R41K, L63T, I64V, E65D, I72V, I93L	B
Rhee (2005)	CA1113	CA38061	AY796490	SQV, NFV, RTV	56	D30N	Q58E	T12M, K20R, E35D, M36I, R57K, I62V, L63T, I64V	B
	CA1626	CA20334	AY796813	SQV, IDV, Unknown	>152	M46MI, I84IV		L10I, M36MI, N37NS, L63T, H69Q, A71AV, I93IL	B
	CA1833	CA12670	AY796828	IDV, NFV, SQV, RTV	179	M46L, G48V, V82A		L10I, T12S, I13V, G16E, L19V, L63T, A71V, I72T, I93L	B
		CA33923	AY796829	IDV, NFV, SQV, RTV, APV	330	M46L, G48M, I54M, V82A, I84V	L33F	L10I, T12P, L19V, L23LV, L63T, A71V, I72T, T74A, I93L	B
	CA3977	CA14912	AY796970	IDV, SQV, RTV, NFV	104			R8RG, I15V, G16E, E35D, N37S, R41K, L63T, I72V, V77I	B
		CA24384	AY796971	IDV, SQV, RTV, NFV, Unknown	>104			L10LV, I15V, G16E, E35D, N37S, R41K, L63T, I72V, V77I	B
	CA4000	CA21462	AY796982	RTV	12			N37D, R57K, D60E, I62IV, L63T, A71V, I72T, V77I, I93L	B
		CA41316	AY796983	RTV	12			N37D, R57K, D60E, L63T, A71V, I72T, V77I, I93L	B
	CA4345	CA17500	AY797059	IDV, NFV, SQV, RTV	212	M46I, G48Q, I54T, V82F, L90M	K43T	R8RQ, L10I, K20R, E35D, M36I, N37D, R41RK, I62V, L63T, I64M, I72V, V77I, L89M, I93L	B
		CA23508	AY797060	IDV, NFV, SQV, RTV, LPV	277	M46I, G48Q, I54T, V82F, L90M	L33F, K43T	L10I, K20R, E35D, M36I, N37D, R41K, Q61QE, I62V, L63T, I72V, V77I, L89I, I93L	B
	SWC-4520	P4520-1146		IDV	104			L10I, N37S, K45R, I62V, L63T, V77I	B
		4520-2566		IDV, NFV, Unknown	>167			L10I, N37D, K45R, I62V, L63T, C67S, V77I, I93L	B
	SWC-4603	4603-4823		APV, NFV	29	D30N		G16E, E35D, M36MI, L63T, I64V	B
	CA4861	CA16079	AY797177	IDV, SQV, NFV, APV	142	M46L, I54V, V82A, I84V		L10I, E35D, N37D, K55R, R57K, D60E, I62V, L63T, I64V, I66F, A71V	B
		CA33670	AY797178	IDV, SQV, NFV, APV, RTV	256	M46L, I54LV, V82A, I84V	L33F	L10I, I13V, K20KT, E35D, N37D, K55R, R57K, D60E, I62V, L63T, I64IV, I66F, A71V, T91S, I93V, F99L	B
		CA37726	AY797179	IDV, SQV, NFV, APV, RTV	260	M46L, I54IV, V82VA, I84IV	L33LF	L10I, I13IV, E35D, N37NDGS, K55KR, R57RK, D60E, I62V, L63T, I64V, E65ED, I66F, A71AV, T91TS, I93IV	B
	CA5249	CA23626	AY797274	IDV, SQV, RTV	39			I62V, L63T, V77VI	B
		CA33241	AY797275	IDV, SQV, RTV	39	M46I, I54IV, V82A, L90M	F53LW	Q7QL, L10I, R41K, I62V, L63T, A71V, I93L	B
	CA7101	CA17570	AY797519	SQV, RTV	154	M46L, G48T, I54V, V82A, I84V	L24I	L10I, T12TI, I13V, G16E, K20I, L63T, I72T, T74S, V77I, L89M, T91A	B
		CA33576	AY797520	SQV, RTV	239	M46L, G48T, I54V, V82A, I84V	L24I	L10I, I13V, G16E, K20I, L63T, I72T, T74S, V77I, L89M, T91A	B
		CA37746	AY797521	SQV, RTV	299	M46L, G48T, I54V, V82A, I84V	L24I	L10I, I13V, G16E, K20I, L63T, I72T, T74S, V77I, L89M, T91A	B
	CA9694	CA23727	AY797805	IDV, SQV, RTV	290			L10I, I13V, G16E, L63T, I72IV, V77I	B
	CA9862	CA24303	AY797892	IDV, NFV	169	D30N, M46L		L63T, A71AV, V77VI	B
	CA9915	CA24488	AY797925	NFV	55			K14R, G16E, N37T, R41K, I62V, L63T, I64L, I72T, V77I	B
		CA34249	AY797926	NFV	55			K14R, G16E, N37T, R41K, I62V, L63T, I64L, I72T, V77I	B
		CA48221	AY797927	NFV, ATV	112	I50L		K14R, G16E, N37T, R41K, I62V, L63T, I64L, I72T, V77I	B
		CA48223	AY797928	NFV, ATV	121	I50L		K14R, G16E, N37T, R41K, I62V, L63T, I64L, A71AV, I72T, V77I	B
	CA14205	CA41366	AY798009	IDV, NFV	315		L24LI	Q18L, K20KT, E35D, M36I, N37E, D60E, I62IV, L63T, I64V, I93IL	B
	CA14357	CA33582	AY798055	IDV	56			Q18QE, N37NS, L63T, V77VI	B
	CA16418	CA38996	AY798249	RTV, IDV	78			K14R, Q18H, E35D, M36I, N37D, I62IV, L63T, I64L, C67CS, A71V, I72T, V77I, I93L	B
Baxter (2006)	12-1870	1870-30811	DQ875973	PI	NA	L90LM		R8A, L63T, I64IV, H69Y, I72T, V77I	B
	12-1763	1763-30424	DQ876044	PI	NA	M46L, I54V, V82A, I84V		T4S, L10V, T12M, I15V, L19V, K20R, M36I, L63T, A71V, I72T, T74E, I93L	B
	12-1203	1203-30325	DQ876063	PI	NA	M46L, G48V, I54V, V82A	L33F	L10V, I13V, N37HY, R41I, I62V, L63T, T74A, I85V, L89M, T91A	B
	12-3125	3125-30501	DQ876096	PI	NA	M46L, G48V, V82A		L10V, T12I, I15V, G16A, N37D, R41K, K43KR, L63T, I72T, T74A, V77I	B
	12-4008	4008-30129	DQ876164	PI	NA			I15V, M36I, L63T, I64V	B
	12-2269	2269-30812	DQ876322	PI	NA	M46ML, G48GV, I54IV, V82VA, I84IV, L90LM	K43T	L10I, I15IV, K20KR, E35D, M36MI, D60DE, I62V, L63T, A71V, I72T, I93L	B
	12-2370	2370-30729	DQ876342	PI	NA			L10I, I15V, G16GE, R41K, L63T, H69HQ, I93L	B
	12-1061	1061-30325	DQ876376	PI	NA	V32I, M46L, I47V, I54M, I84V, L90M	L33F	I13V, E34EQ, R41K, L63T, I64L, I66L, A71V, I72T, T74A, V77I, I93L	B
	12-1069	1069-30528	DQ876395	PI	NA	M46I, I54V, L76V, V82A	K43T	L10IV, T12I, I15V, K20R, E35D, M36I, R41K, K55R, D60DE, Q61N, I62IV, L63T, E65D, H69HR, I72T, T74S, L89M	B
	12-1342	1342-30423	DQ876445	PI	NA	M46L, I54V, I84V, L90M	L10F, L33F, K43T, T74P	I13V, E34Q, M36MI, L63T, A71V, I72V, T91S, I93L	B
	12-1811	1811-30513	DQ876448	PI	NA	M46L, G48V, I54V, V82S, I84V	L33F, T74P	L10I, I13V, G16E, K55R, L63T, V77I	B
	12-1277	1277-30417	DQ876477	PI	NA	V32I, M46I, I47V, I54L, I84V, L90M		L10V, E34Q, M36MI, N37S, I62V, L63T, H69Q, K70Q, A71V, I72T, Q92K, I93L	B
	12-2230	2230-30709	DQ876606	PI	NA			L10I, N37S, L63T, I72T, V77I, I93L	B
	12-2235	2235-30730	DQ876623	PI	NA	I47IV	F53FL	L10I, T12Q, I13IV, G16GE, M36I, N37ND, R41K, R57K, Q61QE, I62V, L63T, I64IV, E65ED, C67CGW, A71AV, I93L	B
	12-2112	2112-30813	DQ876638	PI	NA	M46L, G48V, I54L, V82A, I84V		L10H, V11P, I13V, L19V, K20I, I62V, L63T, I64V, T74S, T91A	B
	12-1208	1208-30507	DQ876652	PI	NA	M46L, I54V, V82A, L90M	L33I, K43T, F53L	L10I, G16E, K20R, E35D, M36I, N37NI, K55R, R57K, D60E, I62IV, L63T, I64V, A71V, I85V, Q92K, I93L	B
	12-2150	2150-30818	DQ876682	PI	NA	M46I, I54LV, L76V, V82A	L33F	L10I, I13V, G16E, M36IV, P39P_EK, K43KQ, K55R, D60E, Q61D, L63T, C67Y, I72T, T74TS, L89M	B
	12-1594	1594-30822	DQ876688	PI	NA	M46MI, I54V, I84V, L90M	L10F, Q58E	K20R, E35D, M36I, N37S, R41RK, I62V, L63T, A71V, I72T, T74S, L89M, Q92K, I93L	B
	12-2218	2218-30814	DQ876750	PI	NA			L10I, K14R, I15V, G16E, P39PS, L63T, V77I, I93L	B
	12-1715	1715-30409	DQ876853	PI	NA	L90M		L10I, N37S, R41K, D60E, I62V, L63T, V77I, I93L	B
	12-1188	1188-30421	DQ876974	PI	NA	M46I, I54V, V82F		L10I, I13V, I15V, R41K, Y59S, L63T, I72V, V77I, I93L	B
	12-1548	1548-30811	DQ877056	PI	NA	M46MI, I54V		L10I, I15V, E35D, M36I, N37Q, R41K, L63T, I93L	B
	12-1726	1726-30502	DQ877094	PI	NA	M46L, G48V, I54S, V82A, L90M	L33F, Q58E	L10I, I13V, G16E, I62V, L63T, A71V, V77I, I93L	B
	12-1738	1738-30617	DQ877141	PI	NA	G48V, I50V, I54S, V82A	L33F, K43T	Q7E, L10IV, I13IV, G16A, E34Q, R41K, L63T, A71V, V77I, I93L	B
	12-3150	3150-30610	DQ877160	PI	NA	M46L, G48V, I54S, V82A	L33F, K43T, T74TP	L10I, I13V, K14R, L19Q, R41RK, L63T, A71V, V77I, I93L	B
	12-3030	3030-30312	DQ877241	PI	NA	M46I, I54V, V82A	L24I, Q58QE	L10I, K20R, M36I, R41K, I62V, L63T, I64V, E65D	B
	48-1004	1004-30609	DQ877311	PI	NA		T74P	I15V, E35D, M36I, R41K, R57K, Q61N, L63T, E65D, I72T	B
	48-1098	1098-30730	DQ877349	PI	NA	M46L, L76LV, V82A	L24I	L10I, I15V, K20R, E35D, M36I, R41K, K55KR, R57K, Q61N, L63T, I66IV, A71AV, I72T, I93L	B
	48-1032	1032-30908	DQ877389	PI	NA			T12N, L19V, K20I, M36I, R41K, L63T, I72V, T74S	B
		1032-31009	DQ877388	PI, RTV, TPV	>4			T12N, L19V, K20I, M36I, R41K, L63T, I72V, T74S, Q92QH	B
	48-1022	1022-30617	DQ877402	PI	NA	M46L, I54V, V82A	L24I, G48E	L10Y, K20M, E35D, M36I, N37E, K55N, I62V, L63T, I64V	B
	48-1833	1833-30924	DQ877469	PI	NA	M46MI, I54IV, L76LV, V82VA		L10I, G16GE, K20KR, M36I, N37ND, R41RK, L63T, I72IV, L89LM	B
	48-1252	1252-30605	DQ877777	PI	NA	G48V, I50V, I54A, V82A	L33F	L10I, N37D, I62V, L63T, H69Y, A71V, V77I, I93L	B
	48-2013	2013-30324	DQ877845	PI	NA	M46L, I54V, V82A	L24I, Q58QE	L10V, I15V, K20R, E35D, M36I, I62V, L63T, I72T, T74A, L89M	B
	48-2226	2226-30423	DQ877868	PI	NA	M46L, I54V, L76LV, V82A, L90M		L10I, T12P, K14R, K20M, E34Q, E35D, M36I, N37S, R41K, I62V, L63T, I64V, A71V, T74S, I93L	B
	48-3003	3003-30225	DQ877913	PI	NA	M46MI, I54V, V82A, I84V	L23I, L24LI, F53FL	L10I, I15V, G16GE, L19V, K20M, E35D, M36I, R41RK, K45N, K55KR, Q61QH, I62V, L63T, I64V, E65D, I72V, I85IV, T91S	B
	48-3018	3018-30725	DQ877928	PI	NA	G48V, I50V, I54A, V82A	K43T	L10I, I13V, G16E, K20I, E35D, M36I, N37E, D60N, I62V, L63T, I72T, T74A, L89M	B
	48-3084	3084-30520	DQ877993	PI	NA	M46L, G48V, I54S, V82A	L33F, F53L	L10IV, I13V, G16E, N37D, I62V, L63T, A71I, V77I, I93L	B
	48-3225	3225-30521	DQ878132	PI	NA	M46L, I54V, V82A, L90M	L23I, L33F, K43T, F53L, T74P	L10I, I13V, L19I, K20R, E35D, M36I, N37T, K55R, I62V, L63T, C67E, I72T, L89M	B
	48-3276	3276-30716	DQ878183	PI	NA	M46L, I54A, V82A, L90M	L10F, G73S, L89V	Q7QE, I15V, G16E, M36L, R41RK_KR, K55R, R57RK, Q61H, L63T, K70T, A71V, I93L	B
	48-4014	4014-30408	DQ878250	PI	NA	M46L, I84V, L90M	L10F, V11I, G73C, L89V	I13V, I15V, G16AE, K20V, I62V, L63T, I64V, C67F, T74E, V77VI, P79A	B
	48-4104	4104-30224	DQ878334	PI	NA	M46I, I54V, V82A, I84V, L90M	L33F, F53FL, Q58E	T4S, L10I, V11L, I13V, G16E, L19I, M36I, Q61R, L63T, L89I, T91S	B
	48-4122	4122-30409	DQ878353	PI	NA	M46L, G48V, I54V, V82A, I84IV		L10I, K14R, P39Q, I62V, L63T, I64L, A71V, I72T, V77I, T91TS, I93L	B
	48-4247	4247-30519	DQ878480	PI	NA	M46I, G48V, I50V, I54A, V82A	L33F, Q58E	L10I, E34Q, P39Q, F53FY, D60E, Q61E, I62V, L63T, A71V, I72T, V77I, I93L	B
	48-4302	4302-30806	DQ878520	PI	NA	G48M, I54V, L76V, V82A, I84V	L33F, F53L	L10I, I13V, G16E, K20M, M36V, I62V, L63T, H69R, A71V, T74A, I93L	B
	48-5012	5012-30509	DQ878547	PI	NA	I54V, V82A, L90M	L33F, K43T, G48W, F53L	L10I, T12N, I13V, M36L, I62V, L63T, T74A, L89I	B
	48-6054	6054-30617	DQ878653	PI	NA	M46L, I54V, L76V, V82A	L10F	I13V, G16E, N37T, L63T, I64V, T74S, T91A	B
	48-6066	6066-30829	DQ878664	PI	NA	M46L, I54V, V82A	L10F, L33I, Q58E	I13V, K20R, M36I, N37T, R41K, I62V, L63T, I64V, T74S	B
	48-6069	6069-30925	DQ878667	PI	NA	M46L, V82A	L24I	L10I, I13IV, N37D, K55KR, D60E, Q61QE, I62V, L63T, I64MV, C67E, A71V, I72T, T74A, V77I, I93L	B
	48-6158	6158-30704	DQ878734	PI	NA	G48V, I50V, I54S, V82A	L33F, Q58E	Q7QE, L10I, G16A, L19I, E34Q, L63T, A71V, I72T, T74S, V77I, I93L	B
	48-6173	6173-30724	DQ878746	PI	NA	V32I, M46I, I47V, I54M, V82A	L10F, L33F, K43T	G16GE, K20R, E35D, M36I, N37D, K55KR, R57RK, L63T, I64V, E65D, H69K, A71V	B
	48-6186	6186-30723	DQ878758	PI	NA	M46I, G48V, I50V, I54T, V82A		L10I, T12P, K14R, G16E, K20R, E34N, E35D, M36I, N37S, R41K, L63T, I64V, I85V	B
	48-6249	6249-30929	DQ878808	PI	NA	V32I, M46I, I47V, I54M, V82A	L10FV, L33LF, K43T	I15V, G16E, K20M, E34EQ, M36V, I62IMV, L63T, I72T, T74A, L89M	B
	48-6260	6260-30828	DQ878817	PI	NA	V32I, M46I, I47A, V82A	K43T	L10I, K20R, M36I, I62V, L63T, I64V, E65D, A71V, I93IL	B
	48-6299	6299-30912	DQ878841	PI	NA	M46I, I47V, G48L, I54T, V82A, L90M	V11I	L10V, T12P, I13V, K14R, I15V, G16E, K20I, M36I, F53Y, L63T, I64V, H69K, A71I, T74S, I93L	B
	48-6324	6324-30923	DQ878858	PI	NA	L90M		L10I, I13V, G16GE, M36I, R41K, I62V, L63T, I64IV, A71T, I72T, I93L	B
	48-6341	6341-30918	DQ878864	PI	NA	M46MI, G48M, I54S, V82A, L90M		L10IV, K20R, M36I, N37D, Q61QHKN, I62V, L63T, I64V, H69K, A71V, T74S, I93L	B
	48-7193	7193-30725	DQ879020	PI	NA	M46I		L10V, I13V, K14R, N37S, L63T, T74S, V77I, I93L	B
	48-9205	9205-30917	DQ877486	PI	NA	M46I, I54V, L76V, V82A		L10I, I13V, G16E, L19I, L63T, H69K, T74A, L89M	B
	48-9028	9028-30825	DQ877497	PI	NA	M46I, I47V, I54V, V82F	Q58E	L10I, K20I, E35N, M36I, N37D, I62V, L63T, I72T, V77I, I85V, L89M	B
	48-9346	9346-30923	DQ877525	PI	NA	M46I, G48Q, I54V, V82A, I84V	L24I, Q58E	L10I, T12P, I15V, K20R, M36I, I62V, L63T, I64V, E65D	B
	48-9169	9169-30904	DQ877556	PI	NA	V82VA	Q58QE	L10I, I13IV, K20KR, M36I, I62V, L63T, I64IMV	B
	48-9372	9372-30929	DQ877681	PI	NA	M46L, G48V, I54V, V82T, I84V		L10I, I13V, K14KN, G16E, K20R, M36I, L63T, H69Q, T74A, L89I	B
	48-9115	9115-30924	DQ877706	PI	NA	M46I, V82A, I84V	L33F, Q58E, T74P	L10V, I13V, K20R, M36I, N37D, R41RK, I62V, L63T, I64V, E65D	B
	48-8013	8013-30811	DQ879058	PI	NA	M46I, G48V, I54S, V82A, I84V	K43T	L10I, E34Q, I62V, L63T, I64V, E65D, I72V, T74S, V77I, I85V, T91A	B
Mo (2006)	HM_A3	HM_A3		SQV, RTV		M46L, I84A		L10I, L63T, A71V	B
Sanabani (2006)	02BR005	02BR005	DQ358806	PI	NA			L10I, K20R, E35D, M36I, L63T, I72T, I93L	B
Santos (2006)	091	091PR_RT	AY275754	SQV, IDV, Unknown	>183			G17E, L63T, E65D	B
Eyer-Silva (2007)	BRSAP08	04BRSAP08	DQ899705	RTV, IDV				N37S, L63T, V77I	B
Rios (2007)	CH127	MR_CH127	EF194029	Unknown, IDV	NA			T12P, L19T, N37T, L63T, A71T, I72T, V77I, I93L	B
von Wyl (2007)	111	10324319	EF449940	PI	NA			I15V, L19I, R41K, L63T, E65D	B
	78	10516898	EF449953	RTV, PI	NA			K20R, M36I, N37K, R41K, Q61QE, L63T, H69K, I93L	B
Zolopa (2007)	2	AZ_2		RTV, ATV	24	I50L	L33F	E35D, M36I, N37D, K45I, L63T, G78GR	B
Riddler (2008)	RG12476	RG12476w44		LPV	40			I13V, I15V, L19I, N37S, L63T, H69R, K70T	B
	RG21379	RG21379w108		LPV	108			P39Q, I62V, L63T, A71V, I72IT, I93L	B
	RG50847	RG50847w7		LPV	7			L10V, L63T, I72T, T74S, V77I	B
		RG50847w15		LPV	12			L10V, K43KR, L63T, I72T, T74S, V77I	B
	RG58361	RG58361w68		LPV	67			K14Q, G16A, P39S, D60E, I62V, L63T, I72V, V77I	B
	RG77307	RG77307w43		LPV	37			L19I, L63T	B
	RG96878	RG96878w13		LPV	13			G16E, I62V, L63T, I72E, V77I	B
Rosen-Zvi (2008)	19	00p19-1		IDV, SQV, NFV, RTV	80			L10I, I13V, K14R, I15V, G16E, E35D, N37S, R41K, K45KR, L63T, I72T	B
	79	06p79-2		RTV, ATV	8			L10LI, I62V, L63T, I64IL, A71V, I72V, V77I, I93L	B
Cardoso (2009)	3064	BRGO3064	FJ638433	PI	NA			T12A, I15V, L19I, E35D, M36I, I62V, L63T, I72V, V77I, V82I, L89M	B
	3071	BRGO3071	FJ638435	PI	NA			N37S, L63T, V77I	B
Rhee (2009)	CA1833	CA50894	GQ208286	IDV, NFV, SQV, RTV, APV	440	M46L, G48M, I54M, V82A, I84V	V11VI, L33F	L10I, T12P, I13V, K14R, L19V, L63T, A71V, I72T, T74A, P79PS, I93L	B
	CA7889	CA20332	FJ983241	IDV, NFV, SQV, RTV, APV	183	M46I, I84V	L10F, L33F, F53L, T74P	L63T, L89M	B
Dau (2010)	06550A	06550A	GU581759	PI	NA	D30N	N88ND	I15V, K20MV, E35EG, M36IV, L63T, A71V	B
	06749A	06749A	GU581776	PI	NA	M46I, G48V, I54T, V82S	L24I, L33F, Q58E	L10I, I13V, Q61N, L63T, I64V, I72V, T74A, V77I	B
	07866A	07866A	GU581876	PI	NA	M46I, I54V, L76V	L10F	T12P, I13V, G16E, K20T, L63T, I64V, E65D, I72V	B
	09315A	09315A	GU581965	PI	NA		L33F	I13V, N37S, P39S, L63T, E65ED, I72V, V77I	B
	09655A	09655A	GU581975	PI	NA	M46I, I54LV, V82VF, I84IV	F53FL	L10I, L19Q, K43KQ, L63T, C67W, I72T, V77I	B
Rangel (2010)	N414	N414	GU807494	PI	NA			I13V, R41K, L63T, I64M, V77VI	B
Jones (2012)	129132	129132	JN669461	PI	NA			E35ED, N37S, P39PS, R41KQ, K43R, L63T, A71V, I72T, V77I, I93L	B
	129904	129904	JN669476	PI	NA			T12N, G16E, L19I, E35D, N37S, L63T, I64V, V77I, I93L	B
	140902	140902	JN669592	PI	NA			L10I, G16E, P39S, R57K, I62K, L63T, I64V	B
	143225	143225	JN669638	PI	NA			N37S, L63T, I72V, V77I	B
	148146	148146	JN669707	PI	NA	M46I, V82T	K43T	T12KN, L19I, K20I, E35D, M36I, R41K, K55R, I62IV, L63T, I64IV, E65D, A71AV, I72T, T74A, I93IL	B
	148316	148316	JN669711	PI	NA			L10I, K14R, I15V, N37A, R41K, L63T, C67S, H69Y, I72T	B
	151877	151877	JN669769	PI	NA	I54A, V82F, L90M	L33I	L10I, T12THNP, I13IV, G16E, L19IV, K20R, E34EK, E35D, M36I, D60E, I62V, L63T, A71V, I72T, I93L	B
	152795	152795	JN669787	PI	NA	M46I, I54V, I84V	L24I	L10I, K20R, E35D, M36I, N37S, R41K, L63T, A71V, I72T, V77I, T91S, I93L	B
	155075	155075	JN669831	PI	NA	M46L, I54V, L76V, V82A, L90M		L10I, I15V, G16E, Q18QH, K20M, M36I, N37D, K55R, R57K, Q61N, L63T, A71V, I72T, I93L	B
	156113	156113	JN669851	PI	NA			T12K, I15IV, L19I, R41K, R57RK, Q61N, L63T, E65D, I72T, V77I, P79PS	B
	160640	160640	JN669989	PI	NA			L10V, E35D, N37S, R41K, L63T, I64L, A71V, I72T, I93L	B
	163241	163241	JN670059	PI	NA	M46I, L90M		T12KN, K20I, N37T, R41RK, K55R, I62IV, L63T, I64V, E65D, A71AV, I72IT, T74TS, V77I, I93L	B
	166747	166747	JN670134	PI	NA			L10I, I15V, L63T, I72V, I93L	B
	167539	167539	JN670154	PI	NA	M46MI, I54V, L76V, V82M	L24I, L33F, K43T	L10V, I13V, K20R, E35D, M36I, N37E, G51GA, R57K, Q61N, I62V, L63T, V77I	B
	167789	167789	JN670164	PI	NA	I54V, V82A	L33F	L10I, I13V, G16E, K20T, M36I, R41K, F53I, L63T, I72V	B
	169379	169379	JN670198	PI	NA	I50L, V82A	Q58QE	I15V, K20R, E34K, M36I, R41K, K43R, Q61D, L63T, E65D, I72T, T74S	B
	173237	173237	JN670318	PI	NA	V32I, M46I, G48A, I54V, V82A	K43T, F53L	L10V, K14R, N37S, L63T, A71V, I72T, T74A, V77I, I93L	B
	176192	176192	JN670388	PI	NA			T12N, L33V, R41K, L63T, I64V, I93L	B
	176775	176775	JN670413	PI	NA	I54IV, V82VF, L90LM	L33LI	T4S, L10I, I13IV, G16E, L19I, K20I, M36I, K43R, Q61H, L63T, I64V, A71AT, P79PHQ, I85IV, Q92K	B
	178197	178197	JN670474	PI	NA	M46I, I54V, L76V, V82A, L90M	L33F, F53L, Q58E	L10I, I13V, I15IV, G16E, M36L, R41R_R, K43KR, R57K, I62V, L63T, A71V, T74K, I93L	B
	178576	178576	JN670486	PI	NA			N37S, L63T, K70R, I72T, V77I	B
	178966	178966	JN670495	PI	NA			L10I, I13V, I15V, G16E, K20M, E35D, M36I, R41K, R57K, Q61N, L63T, A71S, I72T	B
	180346	180346	JN670544	PI	NA			T12S, I13V, L19I, N37S, R41K, K43R, Q61H, L63T, I64L, I72T	B
	183432	183432	JN670648	PI	NA	I54V, V82T, L90M	F53L	L10V, I15V, G16E, K20R, E35D, M36I, N37D, Q61N, L63T, A71V, T74S	B
	183985	183985	JN670669	PI	NA			L10I, I13V, I15V, R41K, L63T, I64IV, C67CY, V77I	B
	184847	184847	JN670688	PI	NA			L10I, R41K, L63T, K70R, I93L	B
	188789	188789	JN670759	PI	NA			L10I, T12P, I15V, G16E, L19I, K20T, E35D, P39Q, R41RK, L63T, A71T, I72T, I93L	B
	191349	191349	JN670821	PI	NA			L19LV, N37S, R41K, L63T	B
	193808	193808	JN670910	PI	NA			L10I, I15V, L63T, I64IV, I93L	B
	194823	194823	JN670950	PI	NA			I15V, M36I, L63T	B
	196686	196686	JN671033	PI	NA			T12N, L19LI, R41K, R57K, D60E, L63T, I64V	B
	197249	197249	JN671067	PI	NA	M46I, V82A, I84V	L10F, Q58E	I15V, L19LI, K20R, M36I, R41K, Q61DN, L63T, E65D, I72T, T74S	B
	197471	197471	JN671074	PI	NA	M46I, I84V	L10F, F53L, T74P	I13V, G16E, L19I, K20T, E35D, M36I, P39Q, K55R, R57K, D60E, Q61N, L63T, I64IV, E65D, L89M	B
	197934	197934	JN671096	PI	NA			L10I, L63T, I93L	B
	199214	199214	JN671155	PI	NA	M46I, I50V, I54V, V82A, L90M	K43T, F53L, T74P	L10V, I13IL, K14KM, K20R, E34R, E35D, M36I, R41K, K55R, R57K, I62V, L63T, I64M, A71V, I72T, I93L	B
	199813	199813	JN671183	PI	NA			I15IV, G16E, M36I, N37T, L63T, I64IV, E65D, I72T	B
	202016	202016	JN671249	PI	NA	I54V, V82F	Q58E	L10I, I13V, K20V, E35D, M36I, N37DE, I62V, L63T, I64V, T74S, V77I	B
	202192	202192	JN671261	PI	NA			L10LI, I13V, K14KIMN, I15V, G16E, L19LP, E35D, N37ND, P39PQ, L63T, I72V	B
	203217	203217	JN671302	PI	NA			L10I, I15V, M36I, N37E, R41K, R57K, D60N, Q61D, L63T, I93L	B
	205283	205283	JN671354	PI	NA			T12TA, R57K, L63T, A71V, I72T, V77I, I93L	B
	206655	206655	JN671404	PI	NA			L10I, G16E, K20R, M36I, I62V, L63T, I64V, E65D, C67Q, I72V	B

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