Protease Inhibitors

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Protease Inhibitors

Subtype	B
Gene	PR
Mutation	L63S
Rx	>= 1 PI
IncludeMixtures	No

References	53
Patients	248
Isolates	295

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	Wks	PIMajorDRMs	PIMinorDRMs	OtherMut	Subtype
Condra (1996)	pt-N	ptNW24		IDV	24	M46I		L10I, N37C, I62V, L63S, V77I, I85V, I93L	B
Molla (1996)	RTV-228	RTV228W2		RTV	2	V82A		L63S, I72T	B
	RTV-229	RTV229W16		RTV	16	I54V, V82A		L10I, I13V, K14R, G16E, K20R, M36I, L63S, I64V, A71V	B
Patick (1998)	503-182	503-182W13		NFV	13	D30N	M46V	L63S, I64V, I72V	B
	503-23	503-23W52		NFV	52	D30N		E35D, M36I, L63S, I64V	B
	503-123	503-123W4		NFV	4			I15V, E35D, L63S	B
	503-163	503-163W4		NFV	4			N37D, L63S, V77I, I93L	B
	510-114	510-114W8		NFV	8			I15V, E35D, M36I, I62V, L63S, T91X, I93L	B
	510-25	510-25W12		NFV	12	D30N		L10X, I62V, L63S, C67S	B
Ruiz (1998)	LR-RCC	RCCW24		IDV	24	G48V		L10I, T12E, I15V, L19I, M36I, I62V, L63S, I66V, A71V	B
Cabana (1999)	Cab-k	K21	AF102325	IDV, SQV, RTV	84	G48V, I54T, V82A		L10I, T12E, I15V, L19I, K20R, M36I, I62V, L63S, I64V, A71V, I93F	B
		K24	AF102326	IDV, SQV, RTV	96	G48V, I54T, V82A		L10I, T12E, I15V, L19I, K20R, M36I, I62V, L63S, I64V, A71V	B
		K35	AF102327	IDV, SQV, RTV	140	G48V, I54T, V82A		L10I, T12E, I15V, L19I, K20R, M36I, F53Y, I62V, L63S, A71V	B
Murphy (1999)	ACTG347_0131	131_PR_w12		APV	11			E35D, N37E, L63S, I64V, E65D	B
	ACTG347_0193	193_PR_w12		APV	12	I84IV		L10I, I13V, L63S, I64M, I72V	B
	ACTG347_0068	068_PR_w21		APV	21			L10I, Q18QR, N37S, L63S, V77I, I93L	B
Bacheler (2000)	LB3-P11	P11-9		IDV	9			I13V, G16E, N37D, L63S, I64V, Q92K	B
		P11-16		IDV	16			I13V, G16E, N37D, L63S, I64V, Q92K	B
		P11-21		IDV	21			I13V, G16E, N37D, L63S, I64V, Q92K	B
	LB3-P24	P24-94		IDV	92			I15V, L63S, I93L	B
	LB3-P4	P4-16		IDV	16			L63S, I72V	B
		P4-34		IDV	34			L63S, I72V	B
	LB3-P44	P44-8		IDV	8			L63S, I64M, I72V	B
		P44-14		IDV	14			L63S, I64M, I72V	B
		P44-16		IDV	16			L63S, I64M, H69L, I72V, F99L	B
		P44-35		IDV	35			L10I, L63S, I64M, I72V	B
		P44-44		IDV	44			E35D, L63S, I64M, I72V	B
	LB3-P57	P57-1		IDV	1			K20R, L24S, N37D, L63S, A71V, I93L	B
		P57-12		IDV	12			K20R, N37D, L63S, A71V, I93L	B
		P57-16		IDV	16			K20R, N37D, L63S, A71V, I93L	B
		P57-24		IDV	24	V82A		K20R, N37D, L63S, A71V, T74S, I93L	B
		P57-87		IDV	87	V82A		K20R, N37D, L63S, A71V, T74S, I93L	B
Balotta (2000)	CB-150	CB-150	AF252014	NFV, IDV		M46I, L90M		L10V, K14KR, K20I, T31TP, M36I, I62V, L63S, I64V, T74S, I93L	B
	CB-162	CB-162	AF251979	IDV		V32I, M46I, V82A		L5P, T12S, L19V, I62V, L63S, A71V, I72M	B
	CB-174	CB-174	AF252032	SQV, RTV, IDV		I54V, V82AT, L90M		L10I, I62V, L63S, I64L, C67E, H69K, A71V, V77I	B
	CB-223	CB-223	AF252078	SQV, IDV		M46I, G48M, V82A, L90M		L10I, N37H, R41K, R57K, L63S, H69K, A71T, I93L	B
	CB-241	CB-241	AF251961	IDV				L10LI, I13V, G16E, L63S, I64M, H69K, V77I	B
	CB-284	CB-284	AF251967	IDV				K14R, N37S, R41K, L63S, I64V, H69K	B
	CB-317	CB-317	AF252026	IDV, SQV, NFV, RTV		M46I, I54A, V82A	L24I, L33F, Q58E	L10I, T12S, I13V, G16A, F53Y, I62V, L63S, I64IL, I66F, H69K, A71V, V77I	B
Baxter (2000)	GART-G7	GART-7		PI, RTV	NA			R8RL, T12M, E35D, M36I, I62V, L63S, I64V	B
	GART-NG65	GART-65		PI, NFV	NA	D30N	L10F, N88ND	I13V, K45I, I62V, L63S, A71T, V77I	B
	GART-NG70	GART-70		PI, IDV	NA			L33V, L63S, I64V	B
	GART-NG72	GART-72		PI, IDV	NA	M46I, V82T		K20M, E35D, M36I, L63S, I64V, I85V	B
Masciotra (2000)	SM36	SM36	AF221027	PI	NA			T12N, L19I, R41K, L63S, T96S	B
Sevin (2000)	SA-630469c	SA-630469c	AF226147	SQV	85			I15V, E35D, M36I, N37ND, I62V, L63S, T74TS	B
	SA-231206j	SA-231206j	AF226130	SQV	107	L90LM		T12P, K14R, I15IV, M36I, Q61E, I62IV, L63S, E65ED, A71AV, I93L	B
	SA-172018l	SA-172018l	AF226116	SQV	106		Q58QE	N37DH, G52GV, Q61QP, L63S, E65ED, A71T, I72T	B
	SA-090951c	SA-090951c	AF226098	SQV	99		L33F	I13IV, G16E, N37Q, P39S, R57K, I62V, L63S, I64V	B
Walter (2000)	HW10	HW10_1	AF288807	IDV				T12S, I15V, R41K, L63S, I64V	B
	HW6	HW6_1	AF288800	IDV				I13V, G16E, N37C, I62V, L63S, I64M	B
Bacheler (2001)	DMP003-04	03-04186	AF349323	IDV	27			L63S, I72V	B
	DMP003-44	03-44259B	AF349343	IDV	37			L63S, I64M, E65D	B
Delgado (2001)	ED_V72	ED_V72	AY016882	SQV, NFV				M36I, L63S, I72V	B
	ED_V73	ED_V73	AY016883	IDV				R41K, L63S, I64V, V77I	B
Dunne (2001)	ALD-pt8	ALD-pt8	AF369801	PI	NA	M46I, V82T	L24I	L10I, I15V, K20KR, E35D, M36I, G51A, I62V, L63S, I64V	B
Eshleman (2001)	A054	AF357756	AF357756	RTV	8			I15IV, L63S, V77I	B
	A058	AF357814	AF357814	RTV	47			D60E, I62V, L63S	B
	A069	AF357767	AF357767	NFV	16			L10I, N37CS, R41K, I62V, L63S, I64IM, V77I, I93L	B
Gonzales (2001)	CA1116	CA2517	AY030434	IDV	21			E35D, N37H, R41K, L63S	B
	CA1339	CA3372	AY030534	IDV, NFV	35	D30N		E35D, M36I, K43Q, I62V, L63S, I64V, E65D	B
	CA1458	CA3893	AY030594	IDV, NFV	100	M46L, I54V, V82A		L10I, R41K, D60E, I62V, L63S, I64MV	B
	CA4093	CA9796	AY031085	SQV, IDV, NFV, RTV	145	I84V, L90M		L10I, K20KR, E35D, M36I, I62V, L63S, I64V	B
	CA4349	CA10757	AY031212	NFV	44			L10I, M36I, I62V, L63S, I64IM, I93L	B
	CA4414	CA10829	AY031270	SQV	31			I15V, N37D, D60E, L63S	B
	CA4487	CA11057	AY031330	NFV, IDV	84			L63S, V77VI	B
	CA4578	CA11229	AY031375	IDV	156	N88S		L10I, M46X, I62V, L63S, V77I, I93IL	B
	CA4788	CA11832	AY031448	NFV		D30N, M46I		N37D, K43R, L63S, A71V, I72T, V75I, V77I, I93L	B
	CA5016	CA12555	AY031591	IDV, NFV	78	L90M		M36I, R57K, I62V, L63S, A71V, I93L	B
	CA5042	CA12598	AY031613	IDV, SQV, RTV	165			T12S, L19I, L63S, V77I	B
	CA5058	CA12621	AY031628	NFV, IDV, SQV, RTV	127	M46I, L90M	G73T	E35D, L63S, I64V, A71V, I72V, I93L	B
	CA5140	CA12718	AY031706	IDV, NFV	181	M46L		K20I, N37E, L63S, A71V, T74S, V77I, I93L	B
	CA5200	CA12778	AY031763	NFV	75	D30N	N88D	I13V, E35D, M36I, R41K, I62V, L63S, A71V	B
	CA5301	CA13218	AY031858	IDV	34			L5LV, I62V, L63S, I93L	B
	CA5458	CA13639	AY031998	SQV	18			L63S	B
	CA6413	CA16179	AY032367	IDV	61			L63S, I72V	B
Kempf (2001)	DK-2304	DK-2304		SQV	67	G48V	D30DG	L10I, R41K, I62V, L63S, I64V, T74S	B
	DK-9105	DK-9105		IDV, RTV	21			L10LR, L19I, N37T, D60E, I62V, L63S, V77I	B
Servais (2001)	JS10	JS98113	AJ401924	RTV, IDV	84	M46L, I54V, V82A		L10I, K14R, I62V, L63S, C67D, H69K, A71V, V77I, I93L	B
		JS98318	AJ401947	RTV, IDV	96	M46L, I54V, V82F		L10I, K14R, I62V, L63S, C67D, H69K, A71V, V77I, I93L	B
	JS11	JS98491	AJ401963	IDV	108	I54V, V82F		L10I, K14R, I62V, L63S, C67D, H69K, A71V, V77I, I93L	B
	JS23	JS99284	AJ401973	SQV, IDV	96	G48GV	L10F, N88T	I15V, K20R, E35D, M36I, R41K, M46X, I62V, L63S, A71V, I72V, L89M, I93L	B
Cuevas (2002)	CU49	CU49	AF425430	NFV				N37S, R41K, L63S, I64L	B
Maguire (2002)	SW32533	SW32533		APV	48	M46I, I50V		I15V, M36I, I62V, L63S, E65D, V82I	B
Margot (2002)	MM-212736523	2127365231		PI	NA			G16E, I62V, L63S	B
	MM-304036676	3040366761		PI	NA	D30N	N88D	L10V, I13IV, G16E, L19I, E35D, M36I, I62V, L63S, I72V	B
	MM-216636574	2166365741		PI	NA			N37D, L63S, V77I, I93L	B
	MM-549536852	5495368521		PI	NA			I15V, N37D, L63S, I93L	B
Romano (2002)	MZ-pt40	pt40-t0	AF493375	SQV, RTV, NFV, APV		M46I, I84V, L90M	F53FL	I15V, G16E, K20I, Q61H, L63S, H69K, A71V, V77I, I85V	B
		pt40-t1	AF493414	SQV, RTV, NFV, APV, LPV		M46I, L76V, I84V, L90M	F53L	L10I, I15V, G16E, K20I, Q61H, L63S, H69K, A71V, V77I, I85V	B
	MZ-pt35	pt35-t0	AF493370	SQV, IDV, NFV		L90M		L10I, T12S, L19T, K20KI, I62V, L63S, A71T, V77I	B
		pt35-t1	AF493409	SQV, IDV, NFV, LPV		L90M		L10I, T12S, L19T, K20IM, I62V, L63S, A71T, V77I	B
Tural (2002)	57699	57699		IDV, NFV	59	D30N	N88D	I62V, L63S, A71V, V77I, I93L	B
	193544	193544		SQV, RTV	141	I54V, V82A, L90M	F53L, G73C	L10I, I15V, G16E, K20M, M36I, N37D, L63S, A71V, I72R	B
	284395	284395		NFV	53	D30N		L10V, I13V, G16E, N37Q, L63S, A71V, V77I	B
	880417	880417		IDV, NFV	153	G48V, V82A		L10I, I15V, G16E, N37Q, L63S, I93L	B
	880712	880712		IDV	99			N37S, L63S, I64V	B
	880718	880718		RTV	123			L63S, I64L, E65V	B
Venturi (2002)	GV-6	GV-6.1	AF517258	SQV	55			L63S	B
	GV-31	GV-31.1	AF517283	RTV	60			L10I, I13IV, E35D, M36I, I62V, L63S, I64M	B
	GV-39	GV-39.1	AF517291	SQV	140	L90M		K20KR, I62V, L63S, A71V, V77I, Q92QL, I93L	B
	GV-42	GV-42.1	AF517294	NFV	76	D30N	N88D	I13V, I62V, L63S, I64M, A71V, V77I	B
de Sa Filho (2003)	BREPM071	BREPM071	AY182801	IDV				R41K, L63S, V77I	B
Gonzales (2003)	CA1116	CA9442	AY305977	IDV, SQV, RTV, NFV	74			E35D, N37H, R41K, L63S	B
Holguin (2003)	SP_LP33	SP_LP33	AF455628	PI	NA			L63S, V77I	B
Monno (2003)	ML_Pat20	ML_Pat20		PI	NA	L90M		L19I, L63S, I64V, V77I	B
	ML_Pat67	ML_Pat67		PI	NA	I54V, V82T		L10I, I13V, K20M, M36I, D60E, Q61N, I62V, L63S, I64V, I66F	B
Saah (2003)	AS-40	AS-40		NFV	79	M46I, L90M	Q58E	L19I, K20T, M36I, I62V, L63S, I64V, V77I, I93L	B
Shafer (2003)	A384_0302	0302c	EF548189	NFV	50			I15V, L19V, L63S	B
	A384_7804	7804b	EF548299	NFV	13			Q7QR, P9PR, K43KN, L63S, I64V	B
	A384_2105	2105b		NFV	11			L19LI, M36MI, N37D, I62V, L63S, Q92K	B
	A384_1486	1486c	EF548878	NFV	94	D30N	N88D	L10I, I13V, K14R, E35ED, M36I, R41K, K45R, I62V, L63S, I64MV	B
	A384_1146	1146b	EF548954	NFV	97			L63S	B
	A384_2922	2922b	EF549020	NFV	26	M46MI		T12N, E35D, L63S	B
	A384_2581	2581b		NFV	1			E35D, N37D, L63S, I64V, E65D, V82I	B
		2581c	EF549163	NFV	137			E35D, N37D, L63S, I64V, E65D, V82VI	B
	A384_0144	0144b	EF549239	NFV	9			E35D, M36I, N37D, D60E, L63S, A71V, V77I, I93L	B
	A384_0187	0187b	EF549320	NFV	39			T12S, L63S, V77I	B
	A384_6657	6657b	EF549370	NFV	24			T12TS, N37D, I62IV, L63S, I64IM, V77I	B
Wu (2003)	CA1339	CA20590	AF544464	IDV, NFV, SQV, RTV	187			M36I, I62V, L63S, I64IV, E65D	B
	CA1458	CA23193	AF544480	IDV, NFV, SQV, RTV	266	M46L, I54V, V82A, I84IV, L90M	L23LI	L10I, R41K, G48X, D60E, I62V, L63S, I64V, H69HR	B
	CA2091	CA13936	AF544525	RTV, SQV, NFV	177	M46MI, L90M		M36MI, L63S, I64V	B
	CA4414	CA12784	AF544558	SQV, NFV, APV	50			T12TA, I15LV, G16GV, N37D, D60E, L63S	B
Colonno (2004)	RC-008-061-188	061-18821		NFV	73			I15V, G16E, L19I, K20T, E35X, M36I, R57K, I62V, L63S, K70R, T74S, I93L	B
Dumans (2004)	263	263	AY390071	RTV	58	V82L, L90M		N37D, I62V, L63S, A71V, I72L, V77I	B
Gomez-Carrillo (2004)	96295	96295	AY365522	PI	NA			R41K, D60E, I62V, L63S, I72V, V77I, Q92K	B
	97285	97285	AY365544	PI	NA	M46ML, I54IL, L90LM	K43KT	Q7QH, T12TP, I15IV, N37E, I62IV, L63S	B
	99401	99401	AY365599	PI	NA			T12TK, K14KR, R41K, D60E, I62IV, L63S, I64IV	B
	100500	100500	AY365611	PI	NA			L19I, E35D, L63S	B
	101626	101626	AY365644	PI	NA			I15V, N37S, R41K, L63S, K70R	B
	106532	106532	AY365750	PI	NA			I15V, N37S, R41K, L63S, K70R	B
	106934	106934	AY365757	PI	NA			K14R, L38LI, I62V, L63S, I72IV, V77I	B
	111946	111946	AY365855	PI	NA			I15AV, N37S, R41K, L63S, K70R, I93L	B
	112454	112454	AY365858	PI	NA			M36MI, R57K, L63S, A71V, I93L	B
	113426	113426	AY365876	PI	NA			L10I, E35D, N37S, I62V, L63S, I64M, I72V	B
	113964	113964	AY365887	PI	NA			T12N, G16E, L19I, M36I, R57K, I62V, L63S, I64V	B
	117782	117782	AY365940	PI	NA	I54V, V82A, L90M	F53L	L10V, I15V, G16E, N37D, L63S, I66F, A71V, T91A	B
Gulick (2004)	RG247	RG247w119		ATV	8			L19T, E35D, N37D, L63S, A71T	B
	RG285	RG285w118		NFV	10			N37D, K55E, R57K, I62V, L63S, K70KE, I72V, V77I, Q92QH	B
	RG287	RG287w34		ATV	9			T12P, K14R, G16E, M36L, I62V, L63S, I64V	B
	RG412	RG412w26		RTV, IDV	6			M36I, I62V, L63S, V77VI	B
Montes (2004)	MB_patTERR	02_TERR707	AJ578167	RTV, IDV, SQV, NFV, LPV	193	M46L, G48A, I54V, V82A, L90M		L10I, K20R, E35D, M36I, N37E, I62V, L63S, I64M, A71V, I93L	B
	MB_patVERG	99_VERG702	AJ578175	IDV, SQV, NFV, RTV	52	M46I		L19Q, K20M, L63S	B
	MB_patMIL	01_MIL704	AJ577951	SQV, NFV, RTV	52	M46I, L90M	F53L	L10I, I13V, N37S, R41K, L63S, I64M, A71V, T74S, V77I, I93L	B
Rhee (2004)	CA4487	CA38068	AY798489	NFV, IDV	302			L63S, V77VI	B
Mo (2005)	9208	9208_d362		PI, LPV	NA			E35D, N37D, L63S, V82I	B
	9226	9226_d167		PI, LPV	NA			L10I, I13V, N37T, L63S, I64V, V77VI	B
Ochoa de Echaguen (2005)	B-0327	B-0327	AY833582	IDV				L23LP, N37S, L63S, V77I	B
Rhee (2005)	CA1116	CA13563	AY796493	IDV, SQV, RTV, NFV, PI, Unknown	>74			E35D, N37H, R41K, L63S	B
	CA1829	CA48175	AY796827	IDV, NFV, SQV, RTV, ATV	339			M36I, I62V, L63S, V82I	B
	CA2091	CA33616	AY796871	RTV, SQV, NFV, IDV	299	M46I, L90M		L63S, I64V, V77I, I93L	B
	CA4093	CA17504	AY797014	SQV, IDV, NFV, RTV, Unknown	>145	I84V, L90M		L10I, K20R, E35D, M36I, I62V, L63S, I64V	B
	CA4414	CA20563	AY797087	SQV, NFV, APV, Unknown	>50			I15V, E35ED, N37D, D60DE, L63S	B
	CA4461	CA23715	AY797103	IDV	130			L10LI, E35D, K45KR, L63S, I64V, E65D	B
	CA4487	CA20418	AY797108	NFV, IDV	169			L63S	B
		CA33929	AY797109	NFV, IDV	262			L63S, V77VI	B
	SWC-2620	P2620-825		IDV, SQV, RTV	67	V32I, M46I, V82A	F53L	L10I, L63S, I64V, E65D, A71V	B
		P2620-1008		IDV, SQV, RTV, NFV	79	M46I, V82A	F53L	L10I, M36X, K45I, L63S, I64V, E65D, A71V	B
		2620-2207		IDV, SQV, RTV, NFV	148	V32I, M46I, V82A	F53L	L10I, K20R, M36I, L63S, I64V, E65D, A71V, Q92X, F99X	B
		2620-3080		IDV, SQV, RTV, NFV, APV	193	V32I, M46I, V82A	F53L	L10I, K20R, M36I, L63S, I64V, E65D, A71V	B
		2620-4108		IDV, SQV, RTV, NFV, APV	251	V32I, M46I, V82A	L33LF, F53L	L10I, K20R, M36I, L63S, I64V, E65D, A71V	B
	SWC-6100	6100-4969		SQV, RTV, APV, Unknown	>105			E35D, N37E, P39S, R57K, I62V, L63S, I64L, A71V, V77I, I93L	B
	SWC-4651	P4651-319		IDV	11		L33I	N37S, I62V, L63S, I64L, A71V, V77I	B
	CA4788	CA13923	AY797153	NFV		M46MI		N37D, K43R, D60DE, L63S, A71V, I72AT, V75VI, V77I, Q92QP, I93L	B
		CA37738	AY797154	NFV, Unknown	NA			N37D, K43R, L63S, A71V, I72T, V75I, V77I, I93L	B
	CA4795	CA17067	AY797161	NFV	100			I15IV, L33LV, L63S	B
	ASRU010	ASRU010		IDV, NFV		D30N	N88D	L10I, I62V, L63S, I93L	B
	CA5016	CA24594	AY797207	IDV, NFV	78	L90M		M36I, R57K, I62V, L63S, A71V, I93L	B
	CA5042	CA20265	AY797210	IDV, SQV, RTV	191			T12S, L19I, L63S, V77I	B
		CA24348	AY797211	IDV, SQV, RTV	191			L5LR, T12S, I13IV, L19I, L63S, V77VI	B
		CA33442	AY797212	IDV, SQV, RTV	191			T12S, L19T, L63S, V77I	B
		CA38122	AY797213	IDV, SQV, RTV	191			T12S, K14KR, L19I, L63S, V77I	B
	CA5058	CA23682	AY797222	NFV, IDV, SQV, RTV	230	M46I, L90M	G73T	L10I, E35D, L63S, I64V, A71V, I72V, I93L	B
		CA48109	AY797223	NFV, IDV, SQV, RTV	369	M46I, L90M	G73T	L10V, E35D, L63S, I64V, H69R, A71V, I72V, I93L	B
	CA5109	CA33640	AY797232	NFV	113			I15IV, E35D, N37D, L63S, I72T	B
	CA5140	CA33854	AY797241	IDV, NFV	182	M46L		K20I, N37E, L63S, A71V, T74S, V77I, I93L	B
	CA6555	CA37698	AY797419	NFV	57			K14M, K43R, I62V, L63S, E65D, A71V, I72T, V77I, I93L	B
	CA6855	CA17029	AY797461	Unknown, RTV, IDV	>5			E35D, N37D, L63S, A71T	B
	CA6880	CA17063	AY797475	IDV	143			L10I, L63S, I93L	B
	CA8071	CA20599	AY797686	NFV	101	D30N		T12S, L19I, K45I, L63S, A71V, T74TS, V77I	B
	CA8404	CA21402	AY797743	IDV	30			L10I, V11A, I62V, L63S, I64IM, C67CY, A71V, V77I, I93L	B
		CA38084	AY797744	IDV	30			L10I, V11A, T12TP, Q61QE, I62IV, L63S, I64IM, C67CY, A71V, I72IT, V77I, I93L	B
		CA42701	AY797745	IDV	30			L10I, V11A, T12P, I62V, L63S, I64IM, C67Y, A71V, I72IT, V77I, I93L	B
	CA9882	CA24388	AY797903	IDV, NFV	235	M46I, L90M		L10I, T12L, L19T, K20I, L63S, A71IV, V77I, I85V, Q92K, I93L	B
	CA9883	CA24392	AY797904	SQV, Unknown	>104			R41K, L63S, I64IV, V77VI	B
		CA41288	AY797905	SQV, Unknown	>104	L90M		R41K, L63S, I64V	B
	CA14497	CA41386	AY798096	NFV	20			I3IV, L10LI, G16E, E35D, L63S, T74TA	B
	CA14545	CA38272	AY798116	NFV	52	I84C		L63S, I64V	B
	CA14661	CA38166	AY798141	LPV	18			M36MI, N37D, L63S, I64V	B
	CA14663	CA34083	AY798142	IDV	91			I15V, E35D, N37D, I62V, L63S, I64M, A71V, I72E, I93L	B
	CA16174	CA38486	AY798185	IDV	243			T12TS, I13IV, I15IV, I62V, L63S, V77I	B
	CA16267	CA38684	AY798210	SQV	362			L63S	B
Baxter (2006)	12-1024	1024-30513	DQ876266	PI, RTV, TPV	>8	M46I, L76LV, V82F, L90LM	L33F, Q58E	L10V, I13V, E35D, M36I, R57K, I62V, L63S, L89M	B
	12-4007	4007-30129	DQ876165	PI	NA	M46L, G48V, I54ST, V82A, L90LM		L10I, K20R, E34Q, E35D, M36I, R41K, I62V, L63S, A71V, I93L	B
	12-2107	2107-30626	DQ876434	PI	NA	M46I, I54IL, N88S	L10F, Q58E	I13V, M36MI, N37E, I62IV, L63S, V77I, L89M, I93L	B
	12-1965	1965-30610	DQ876451	PI	NA			I15V, N37C, R41RK, I62V, L63S, V77VI	B
	12-1503	1503-30619	DQ876625	PI	NA	V32I, M46I, I47V, G48M, I54M, V82A	L33F, F53L	L10V, K14R, G16E, K20R, E35D, M36I, K43I, K55R, R57K, I62V, L63S, A71V, I72V	B
	12-1425	1425-30401	DQ876806	PI	NA			I13V, G16GE, Q61N, L63S, I64L, I72V, V77I	B
	12-1173	1173-30812	DQ876944	PI	NA	M46L	Q58E	L10LI, T12P, I13IV, K14R, I62V, L63S, I64V, C67D	B
	12-1539	1539-30625	DQ877003	PI	NA	M46I, I50IV, I54A, V82A, L90M	L33F	W6W*, L10I, I13V, E34Q, N37H, R41K, I62V, L63S, A71V, V77I, Q92R, I93L, C95F	B
	12-1654	1654-30407	DQ877089	PI	NA	G48M, I54V, V82A, L90M	F53L, N88D	L10IV, L19I, K20R, E35D, M36I, N37D, R41K, K55KR, R57K, D60E, I62V, L63S, A71V, I93L, C95F	B
	12-3160	3160-30709	DQ877176	PI	NA	M46MI, G48GV, I54IV, V82AT, I84V	L24LI, F53FL	L10I, T12P, I13IV, G16GE, K20KT, E34EQ, N37ND, K55KR, I62V, L63S, I66IF, A71I	B
	12-3070	3070-30428	DQ877208	PI	NA			L10I, I15V, L63S, I93L	B
	48-1076	1076-30630	DQ877336	PI	NA			L63S, I64V, V77I	B
		1076-30925	DQ877337	PI, RTV, TPV	>12			L63S, I64V, V77I	B
	48-1113	1113-30707	DQ877378	PI	NA			L10V, I15V, M36I, R41K, R57K, Q61N, L63S, I64L, I93L	B
	48-1036	1036-30618	DQ877391	PI	NA			L10I, I13IV, L63S, I64V, E65D	B
	48-1269	1269-30814	DQ877790	PI	NA	G48V, I54A, V82A	K43T	L10I, I13V, K20IM, E35ED, M36I, N37D, I62V, L63S, I64V, H69Y, I72IV	B
	48-3051	3051-30326	DQ877962	PI	NA	M46L, I54V, V82A, L90M	K43T	L10I, K20R, E35D, M36I, N37E, R41K, R57RK, I62V, L63S, I64IM, A71V, I72IT, V77I, I93L	B
	48-3137	3137-30411	DQ878048	PI	NA	M46L, G48GV, I54IV, V82A		L10I, L63S, A71V, V77I, I93L	B
	48-4219	4219-30423	DQ878453	PI	NA	D30DN, M46MI, I54V, V82VAIT, L90LM	L10FI, L33LF, F53FL, N88D	T12TP, I13V, I15IV, G16E, K20KT, E35EG, M36X, R41RK, K45T, I62V, L63S, I64IV, C67CY, A71AV, I72IV, V77VI, I93IL	B
	48-4239	4239-30513	DQ878470	PI	NA			L10I, L63S, V77I, I93L	B
	48-4277	4277-30626	DQ878501	PI	NA			L10I, I13IM, L19LP, N37D, K43R, D60DE, Q61QE, I62V, L63S, I93L	B
	48-5033	5033-30421	DQ878559	PI	NA	M46I, I54V, L76V, V82T, I84V		L10I, I15V, L19I, K20R, M36I, R41K, I62V, L63S, I64IM, A71V, I72IV	B
	48-6020	6020-30328	DQ878619	PI	NA	G48V, I50IV, I54S, V82A	L33F	L10IV, I13V, G16E, K20KT, D60E, L63S, A71V, V77I, I93L	B
	48-6065	6065-30805	DQ878663	PI	NA		L10LF	G16E, E35D, I62V, L63S, H69K, A71T, V77I	B
	48-6160	6160-30710	DQ878736	PI	NA	M46I, I84V	L10F, N88D	I15V, G16E, K20M, N37S, Q61H, L63S, H69K, V77I, P79A	B
	48-6224	6224-30730	DQ878791	PI	NA	V32I, M46I, I47V, I54M, V82A, L90M	L10F, V11VI, Q58E, G73S, L89V	I13IV, I15IV, G16E, L19V, K20V, E35D, M36I, I62V, L63S, A71V	B
	48-6273	6273-30923	DQ878826	PI	NA	M46I, I54V, V82A	Q58E	L10I, M36MI, K55KR, I62V, L63S, I64MV	B
	48-6293	6293-30910	DQ878838	PI	NA	M46L, I54V, V82A, L90M	F53L, G73T	L10V, T12K, I15V, G16E, L19P, K20I, E34Q, M36I, K45KR, Q61H, L63S, H69K	B
	48-6345	6345-30918	DQ878868	PI	NA	M46I, L76LV, V82F, I84V, L90LM	Q58E	L10V, G16A, F53Y, Q61D, L63S, H69K, V77I	B
	48-9070	9070-30901	DQ877484	PI	NA			K14E, L63S, C67E, H69K, V77I, I93L	B
	48-9345	9345-30923	DQ877523	PI	NA	M46MI, I50IV, I54V, V82A, I84IV	Q58E	L10I, I15V, G16GE, L19I, K20R, E35D, M36I, R57K, D60DE, I62V, L63S, I64L, A71V, V77VI, I93IL	B
	48-9241	9241-30915	DQ877541	PI	NA			K14R, I15V, E35D, N37D, R57RK, L63S, A71V, V77I, I93L	B
	48-9307	9307-30918	DQ877566	PI	NA	D30N	N88D	L10V, I13IV, I15V, K20T, E35D, M36I, R41K, Q61DN, L63S, E65D, A71AV, I72IT	B
Santos (2006)	053	053PR_RT	AY275743	RTV, IDV	9			T12S, L19I, K43R, L63S, A71V, I72M, I93L	B
Rios (2007)	CH71	MR_CH71.1	EF193966	IDV				L10I, E35D, M36I, R41K, R57K, L63S, I93L	B
von Wyl (2007)	43	698037	EF449816	PI	NA	M46I	Q58E	I13V, L19LI, K20M, E35D, M36MI, L63S, H69Q, L89LM, I93IL	B
	125	4798867	EF449986	PI	NA	D30DN		I15V, L19I, E35D, M36I, L63S, H69K, I93L	B
	139	5202270	EF449873	PI	NA			T12S, K14R, L19I, E35D, L63S, I64V, V77I	B
	95	662081	EF449985	PI	NA	D30N	L10LF, L33LF, N88ND	K14R, T31TI, N37D, R57RK, L63S, A71AV	B
Zolopa (2007)	6	AZ_6		RTV, ATV	24	I50ILM		N37DE, L63S, A71V, I72Q, V77I, I93L	B
Riddler (2008)	RG11340	RG11340w131		LPV	131			T12P, I13V, L33V, I62V, L63S, I64V, Q92E	B
	RG13636	RG13636w35		LPV	20			L19V, L63S	B
	RG18978	RG18978w74		LPV	74			I13V, G16E, M36I, N37T, D60E, Q61D, I62V, L63S, I64V	B
	RG27982	RG27982w38		LPV	38			I13V, G16E, N37S, P39S, D60E, I62V, L63S, I64V, V77I	B
	RG31923	RG31923w67		LPV	67		K43T	T12P, I13V, L33V, L63S, I64V, C67Y	B
	RG41688	RG41688w13		LPV	13			K14KR, Q61E, L63S	B
	RG47278	RG47278w59		LPV	52			E35Q, N37D, I62V, L63S, I64V, H69Q, A71T, I72V, V77I, I93L	B
	RG55053	RG55053w59		LPV	59			M36MI, D60E, I62V, L63S, I64V	B
	RG79921	RG79921w44		LPV	44			L10LV, T12N, I15IV, L19IT, L63S, V77I	B
	RG8290	RG8290w29		LPV	20			L10LI, I13IV, I15V, M36I, N37D, L63S, I64L	B
Rosen-Zvi (2008)	79	06p79-3		RTV, ATV, LPV	35	V82A		L10I, I62V, L63S, A71V, I72V, V77I, I93L	B
Rhee (2009)	CA4340	CA37829	FJ983167	LPV	138			L10IV, K14R, I15V, L19I, N37D, L63S, E65ED, I72IT, V77I, I93L	B
		CA68600	FJ983169	LPV	143			L10IV, K14KR, I15V, L19I, N37D, L63S, E65D, I72IT, V77I, I93L	B
	CA8428	CA21401	FJ983293	SQV, RTV	84			N37S, R57K, L63S, A71V, I72M, V77I, I93L	B
	CA14501	CA33817	FJ983383	IDV	44			K14R, I15V, L63S, E65D	B
	CA14724	CA34188	FJ983397	NFV	234			I15V, L63S	B
	CA16540	CA39269	FJ983437	NFV	10			T12P, K14R, Q18E, L63S, K70KR, V77I, I93L	B
	CA21008	CA48325	FJ983466	RTV	30			L63S	B
Thomson (2009)	SP_B_001	RU_SP_B_001	FJ009780	RTV, IDV	216	V32I, M46L, V82A	K43T	L10I, N37Y, L63S, A71V	B
	SP_B_009	RU_SP_B_009	FJ009787	IDV	8			N37H, R41K, L63S, V77I, I93L	B
Dau (2010)	06134A	06134A	GU581707	PI	NA			I62V, L63S, I64L, K70R, V77I	B
	06236A	06236A	GU581717	PI	NA			L63S, A71V, I72E, V77I, I93L	B
	06982A	06982A	GU581808	PI	NA	M46I, I50V, I54V, V82ACGS, L90M	L33F	L10I, I13V, N37H, R41K, I62V, L63S, I64IM, A71V, V77I, Q92R, I93L, C95F	B
	08011A	08011A	GU581887	PI	NA	M46MI, I84IV, L90LM		L10V, I13IV, I15V, K20KM, N37NK, R41K, I62IV, L63S, I64V, E65D, A71AV, V75VI, Q92QK, I93IL	B
	09540A	09540A	GU581974	PI	NA			L33V, L63S, I64V	B
	12071A	12071A	GU582061	PI	NA			K43KR, L63S, I64V	B
	12739A	12739A	GU582064	PI	NA			L10I, R41K, I62IV, L63S, E65D, I72T, V77I, V82VI, L89M, I93L	B
Barber (2012)	56144	56144	JQ361688	LPV		I47V		I15V, R41K, L63S, H69K, I93L	B
Jones (2012)	127155	127155	JN669434	PI	NA	I54V, V82A, L90M		L10I, K20R, E35D, M36I, N37D, R57K, Q61N, I62V, L63S, A71V, T74S, V77I, I93L	B
	130225	130225	JN669481	PI	NA			L19T, L63S, I72T	B
	135460	135460	JN669544	PI	NA			T12NS, N37D, R41K, I62IV, L63S, A71V, V77I, I93L	B
	141378	141378	JN669600	PI	NA	I54IL, L90LM		L10IV, I15V, K20KT, E35D, M36MIV, R41K, D60E, I62V, L63S, I93L	B
	145136	145136	JN669653	PI	NA			I13IV, K43KR, I62V, L63S, I72IV, V77I	B
	148896	148896	JN669725	PI	NA			T12P, E35D, M36I, P39PA, R41K, I62IV, L63S, I64V, I72V, V77I	B
	150238	150238	JN669746	PI	NA			L5LF, K14R, N37E, K55R, I62V, L63S, H69N, V77I	B
	150599	150599	JN669751	PI	NA			T12NS, N37D, R41K, I62V, L63S, A71V, I72M, V77I, I93L	B
	154205	154205	JN669812	PI	NA	M46I, N88S		L63S, V77I	B
	157078	157078	JN669877	PI	NA			L63S, V77I, I93IL	B
	157635	157635	JN669894	PI	NA			T12N, L19I, R41K, L63S, V77I, L89LP, I93L	B
	157711	157711	JN669898	PI	NA	G48V, I54V, V82A, L90M	Q58E	L10I, L19LV, K20R, M36I, N37D, I62V, L63S, I64V	B
	160561	160561	JN669982	PI	NA			T12P, K14R, N37A, R41K, L63S	B
	161153	161153	JN669994	PI	NA	D30N	L10LF, N88D	T12N, L19I, R41K, D60E, L63S, I64V, A71V, I72IR, V77I	B
	164867	164867	JN670087	PI	NA			T12P, L19I, L63S, V77I, I93L	B
	165323	165323	JN670095	PI	NA			L19I, N37D, I62V, L63S, V77I, I93L	B
	168324	168324	JN670177	PI	NA			T12E, G16E, L19I, M36I, N37E, P39R, L63S, I72T, V82I	B
	170275	170275	JN670217	PI	NA			T12A, I15V, L19I, K20R, M36I, N37ND, I62V, L63S, K70T	B
	171152	171152	JN670249	PI	NA	D30N	L33LF, N88D	T12N, N37D, R41K, K45KR, I62V, L63S, A71V, I72M, V77I, I93L	B
	176461	176461	JN670398	PI	NA			G16E, M36I, I62V, L63S	B
	181666	181666	JN670578	PI	NA			L10I, L19I, R41K, K43R, L63S	B
	184478	184478	JN670679	PI	NA	M46I, I54V, V82A		L10LI, I15IM, G16E, K20R, M36I, N37D, K55KR, R57K, Q61N, L63S, E65D, I72T	B
	188303	188303	JN670752	PI	NA			T12K, N37A, R41K, L63S, I64V	B
	193231	193231	JN670888	PI	NA			I15V, N37S, R41K, L63S, I72T	B
	195602	195602	JN670989	PI	NA			K14KR, I15V, N37E, L63S	B
	195722	195722	JN670998	PI	NA	L90M		R41K, K43R, I62V, L63S, A71V, V77I, I93L	B
	197775	197775	JN671084	PI	NA			L19I, M36I, I62V, L63S, I93L	B
	198465	198465	JN671119	PI	NA			T12P, K14KR, N37A, R41RK, L63S, I64IM	B
	201016	201016	JN671210	PI	NA	L90M		E35D, M36I, N37D, Q61N, L63S, I72T	B
	201859	201859	JN671238	PI	NA			R41K, K43R, I62V, L63S, A71V, V77VL, I93L	B
	201905	201905	JN671242	PI	NA			N37S, L63S, I64V, I72V	B
	202179	202179	JN671259	PI	NA			T12P, L19T, L63S, V77I, I93L	B
	202601	202601	JN671279	PI	NA			Q18L, L63S, I93L	B
	205344	205344	JN671355	PI	NA			I15V, L19V, N37S, R41K, L63S, V77I	B
	205716	205716	JN671369	PI	NA			T12E, G16E, L19I, E35D, M36I, R41K, I62IV, L63S, I64V, I72R	B
	206281	206281	JN671396	PI	NA	D30N	L33F, N88D	I15IV, E35D, M36I, R41K, R57K, Q61N, L63S, I64L, H69HY, I72T	B

Protease Inhibitors

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