Protease Inhibitors

HOME Genotype-Rx Genotype-Pheno Genotype-Clinical hivdb program

Protease Inhibitors

Subtype	B
Gene	PR
Mutation	M36L
Rx	PI-naive
IncludeMixtures	No

References	63
Patients	180
Isolates	192

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	PIMinorDRMs	OtherMut	Subtype
Hammer (1997)	ACTG320_3611	3611		None		L19I, K20R, L33V, M36L, R41K, Q61H, I64IV, E65ED, V82VI, L89LM, I93ILM	B
Eshleman (2001)	A107	AF357708	AF357708	None		M36L, I64V	B
Gonzales (2001)	CA2205	CA7989	AY030827	None		M36L, N37A, I62V, L63P, I64V, I72V	B
	CA4462	CA11024	AY031306	None		I13V, K14R, I15V, M36L, N37E, I62V, L63S, I64V	B
	CA4912	CA12109	AY031552	None		L10V, I15V, M36L, N37T, R41K, D60E, I62V, L63P	B
Holguin (2001)	SP_M2067	SP_M2067	AF247017	None		K14R, M36L, I62V, L63P	B
Perno (2001)	PCF_Pat20	PCF1881	AF376597	None		L10I, I13V, L19I, M36L, N37T, I62V, L63P, L89M, C95F	B
	PCF_Pat23	PCF3776	AF376699	None		I15V, M36L, N37CS, I62V, I64V	B
	PCF_Pat105	PCF420	AF376538	None	L33I	K14R, M36L, Q61E, L63P, I64V, I93L	B
	PCF_Pat185	PCF2302	AF376627	None		M36L, N37S, L38X, L63P, I64IV	B
Servais (2001)	JS97252	JS97252	AJ010717	None		I3X, M36L, N37X, R41K, R57K, L63P, A71T, V77I, I93L	B
	JS97251	JS97251	AJ279672	None		M36L, R41K, R57K, L63P, A71T, V77I, I93L	B
Cuevas (2002)	CU53	CU53	AF425434	None	L10LF	M36L, N37S, I64V	B
Brindeiro (2003)	BRNE265	BRNE265	AY213333	None		L10V, T12S, I15V, M36L, R41K, I62V, L63C, A71T, C95S	B
Hanna (2003)	HG010	HG010	AY049687	None		M36L, N37S, R41K, L63P	B
	HG044	HG044	AY049641	None		M36L, N37E, I62V, L63P	B
Jorgensen (2003)	JLB_Pat57	HIM419483	AJ419483	None		M36L, N37NS, I62V, L63LP, I64V	B
Shafer (2003)	A384_1383	1383a	EF548229	None		M36L, N37K, R41K, I64V	B
	A384_1022	1022a	EF548559	None		Q18K, M36L, N37S, R57K, I62V, L63P, H69N, F99X	B
	A384_0565	0565a	EF548842	None		M36L, N37S, I62V, L63P, I64V	B
	A384_5611	5611a	EF549132	None		I15IV, M36L, N37D, R57K, I62V, L63HQ, A71V, I93L, F99X	B
	A384_0198	0198a	EF549307	None		W6WL, L10I, G16E, M36L, I62V, L63S, I64V	B
Soares (2003)	BRBS465	BRBS465	AF527179	None		K14KR, G16E, E35D, M36L, I62V, L63H, I64V	B
Vaughan (2003)	VHE_Pat31	VHE031prrt	AY267280	None		I15V, L19Q, E35D, M36L, D60E, Q61E, L63P, A71T	B
Gulick (2004)	RG287	RG287w0		None		T12P, K14KR, G16GE, M36L, R41RK, I62V, L63S, I64V	B
		RG287w18		None		T12P, K14KR, G16GE, M36L, I62V, L63S, I64V	B
	RG433	RG433w-2		None		L10I, I13V, G16E, M36L, N37S, L63T	B
		RG433w64		None		L10I, I13V, G16E, M36L, N37S, L63T	B
		RG433w88		None		L10I, I13V, G16E, M36L, N37S, L63T	B
	RG461	RG461w0		None		L10I, K14R, I15V, M36L, N37D, R57K, I62V, L63H, A71T, I93L	B
		RG461w24		None		L10I, I15V, M36L, N37D, R57K, I62V, L63H, A71T, I93L	B
Kuritzkes (2004)	KDR_pat136	A0159	AY527976	None		M36L, N37S, I62V, L63P, I93L	B
		A0160	AY527977	None		M36L, N37S, I62V, L63P, I93L	B
		A0161	AY527978	None		M36L, N37S, I62V, L63P, I93L	B
		A0162	AY527979	None		M36L, N37S, I62V, L63P, I93L	B
		A0163	AY527980	None		M36L, N37S, I62V, L63P, I93L	B
	KDR_pat137	A0164	AY527981	None		I15IV, M36L, N37S, I62V, L63P, I93L	B
		A0165	AY527982	None		M36L, N37S, I62V, L63P, I93L	B
		A0166	AY527983	None		M36L, N37S, I62V, L63P, I93L	B
Machado (2004)	cs276	cs276	AY569836	None		L10I, I13V, M36L, R57K, L63S, I64V	B
Grossman (2005)	24307	24307PR349		None		W6L, T12S, M36L, D60DE, I62V, L63P, H69Y, I72E	B
Holguin (2005)	00025924	02_25924	AY248411	None		M36L, N37S, R41K, I62V, L63P, I93L	B
Rhee (2005)	CA2205	CA9809	AY796897	None		M36L, N37A, I62V, L63P, I64V, I72V	B
	CA8453	CA21438	AY797767	None		E35D, M36L, L63P	B
	CA16097	CA38320	AY798170	None		I15V, L19I, M36L, N37S, R57K, L63A, I72V	B
Vazquez de Parga (2005)	RU01035	RU01035	EU345742	None		T12P, L19I, M36L, I62V, L63P, G68D, H69I, L89M, I93L	B
Chin (2006)	KRC4325	4325_0408	DQ660447	None		I15V, M36L, N37S, L63T, I64V	B
	KRC4360	4360_0407	DQ660452	None		T12A, I15V, M36L, N37S, L63T, I64V	B
	KRC2349	2349_0211	DQ660484	None		I15V, M36L, N37S, L63T, I64V	B
	KRC2200	2200_0209	DQ660488	None		G16E, M36L, N37S, I62V, L63A	B
	KRC5020	5020_0501	DQ660491	None		I15V, M36L, N37S, I62V, L63T, I64V	B
Jayaraman (2006)	2-00-0626	2-00-0626		None		K14R, L19I, M36L, I62V, L63C	B
Lama (2006)	Pt5005	5005		None		L10V, E35E_TN, M36L, L63A, L89M	B
Andresen (2007)	PMVL 027	PMVL 027	EF514698	None		M36L, N37T, R57K, L63P	B
Brumme (2007)	1221	PR_1221	EF368531	None		I15V, E35D, M36L, N37D, P39Q, R41K, D60E, I62V, L63P	B
	1704	PRRT_1704	EF369014	None		L10I, M36L, I62V, L63AS, I64IV, I72V, I93L	B
	1798	PRRT_1798	EF369108	None		L10I, K20R, E35D, M36L, N37D, L63P, I93L	B
Dilernia (2007)	N84	N84	EF120335	None		I15V, G16E, K20R, M36L, N37S, V75I, I93L	B
	N05	N05	EF120354	None		T12S, I15V, L19I, M36L, N37S, I62V, L63P	B
Gonsalez (2007)	09	HIV_09	GU288739	None		I15V, E35D, M36L, R41K, R57K, L63P, I93L	B
	35	HIV_35	GU288779	None		E35D, M36L, Q61H, I62V, L63P, H69Q, I72T	B
	87	HIV_87	GU288751	None		I13V, I15V, M36L, N37A, R57K, I62V, L63P, H69K	B
Lin (2007)	4V76	4V76	EF078237	None		Q7R, I13V, M36L, P39S, R41K, P44S, K45T, R57K, I62V, L63P, C67F, H69Y, K70N, T74A, N83I, Q92H, F99Y	B
Vicenti (2007)	LR_97	35052R	EF376607	None		L19T, M36L, N37ST, I62V, L63LP, H69Y, I72M	B
von Wyl (2007)	133	7207282	EF449931	None		I15V, M36L, N37T, I62V, I64V	B
		1475858	EF449885	None		I15V, M36L, N37AT, R41RG, Q58QR, I62V, L63PQ, I64V	B
Bang (2008)	078	BJH_078	EF157934	None		I15V, M36L, N37S, L63T, I72T	B
	080	BJH_080	EF157936	None		I3V, I15V, M36L, L63P, I64V	B
Chang (2008)	TW8477a	TW8477a		None		Q7X, I13V, E35E_E, M36L, R41K, R57K, I62V, L63P	B
Ibe (2008)	362	362	AB356353	None		L10I, I15V, M36L, N37S, I62V, L63A, I93L	B
	454	454	AB356419	None		T12S, I15IV, L19LI, M36L, N37NS	B
	531	531	AB356466	None		L10I, I15V, M36L, N37S, I62V, L63A, I93L	B
	567	567	AB356491	None		Q7QH, L10I, I15V, M36L, N37NS, I62V, L63A, I93L	B
McConnell (2008)	NV55	NV55	EU288140	None		V11M, T12S, L19I, M36L, N37S, L63C, I64V	B
Miura (2008)	BEC53	BEC53	EU517916	None		L19LI, M36L, R41K, D60E, I62IV, L63P, Q92T	B
Brown (2009)	CAS_11_1_5767	CAS_11_1_5767	FJ030653	None		G16E, M36L, G40GR, R41K, R57K, I62V, A71T, I93L	B
Brumme (2009)	F8505	F8505	GQ371880	None		T12A, I15V, G16E, M36L, R41K, I62V, L63H	B
	P5594	P5594	GQ372088	None		M36L, I62V, L63P, I64L	B
	W1506	W1506	GQ372222	None		M36L, N37S, R41RK, I62V, L63LHQ, I64V	B
Cardoso (2009)	BRGO3050	BRGO3050	FJ594127	None		I15V, M36L, I62V, L63Q, I64V, C67S	B
Cuevas (2009)	P1328	P1328.1	EU822631	None		I13V, M36L, I62V, L63P, I72M, V75I	B
	P1714	P1714.1	EU822755	None		L10I, I13V, G16E, M36L, I72R	B
Dumans (2009)	13_05	13_05	FJ405053	None		I15V, E35D, M36L, R41K, K45R, L63P, K70R, I93L	B
	451_05	451_05	FJ405054	None		I15V, E35D, M36L, R41K, K45R, L63P, K70R, I93L	B
Fujisaki (2009)	457	457	AB442253	None		L10I, I15V, M36L, N37S, I62V, L63A, I93L	B
	587	587	AB442258	None		L10I, I15V, M36L, N37S, I62V, L63A, H69HY, I93L	B
	608	608	AB442274	None		L10I, T12P, I15V, M36L, N37S, R41RK, I62V, L63V, I64V, I93L	B
	657	657	AB442318	None		L10V, I15V, L19I, M36L, N37S, I62V, L63A, I93L	B
Rhee (2009)	CA8363	CA24546	FJ983277	None		I15V, K20KM, M36L, N37S, I62V, I64V	B
Smith (2009)	PI56	US1997PI56		None		M36L, R57K, L63P	B
	PI149	US2004PI149		None		I15IV, M36L, N37T, P39PS, R57K, I62IMV, L63P, I72IV	B
	PI170	US2004PI170		None		I15V, M36L, N37T, R57K, L63P	B
	PI180	US2003PI180		None		M36L, N37S, R41K, D60E, I62V, L63P	B
	PI196	US2005PI196		None		I15V, M36L, N37IT, R57K, L63P, I72V	B
	PI227	US2005PI227		None		I15V, M36L, N37T, R57K, L63P, I72V	B
	PI286	US2005PI286		None		M36L, N37T, R57K, I62V, L63P	B
	PI344	US2005PI344		None		Q2QR, I15V, M36L, N37T, R57K, L63P, I72V, I93L	B
	CR80	US2006CR80		None		M36L, N37T, R57K, L63P	B
	CR128	US2006CR128		None		T12TK, I15V, L19I, E35ED, M36L, N37NS, R41K, I62V, L63P, T74A	B
	CR129	US2006CR129		None		K20R, E35D, M36L, N37D, I62V, L63S, I64V, I72V	B
	CR144	US2006CR144		None		M36L, I62V, L63P	B
	CR147	US2006CR147		None		M36L, I62V, L63P, C67CY	B
	CR172	US2006CR172		None		T12TA, I15V, M36L, N37T, P39PS, R57K, I62IMV, L63P, I72IV	B
	CR233	US2007CR233		None		I13V, M36L, N37S, R57K, L63P	B
	CR251	US2006CR251		None		T4TP, I15IV, K20KE, M36L, N37T, R57K, L63P, I72IV, V77VI	B
	CR262	US2006CR262		None		M36L, N37T, R57K, L63P, R87RK	B
	CR267	US2006CR267		None		K14R, M36L, N37T, R41RK, R57K, L63P	B
Vercauteren (2009)	pt2097	738438876	GQ398927	None		T12TA, M36L, R41K, R57K, L63P, I93L	B
	pt2036	1089109740	GQ398988	None		I15V, K20R, M36L, R41K, R57K, I62IV, L63LP, V77I, I93L	B
	pt1963	1507603441	GQ399061	None		I13V, I15V, L19V, M36L, R57K, D60E, I62V, L63P	B
	pt1884	1987543711	GQ399140	None		I15V, M36L, R41K, R57K, L63P, V77I, I93L	B
	pt1836	2279348359	GQ399188	None		I13V, K14R, M36L, N37D, R41K, I62IV, L63P, I72IT, V82I	B
	pt1420	4750105544	GQ399604	None		K20R, M36L, I62V, L63P, A71T	B
	pt1404	4823298120	GQ399620	None		I13IV, K14KR, M36L, R41K, R57K, L63P, A71AV, V77I, I93L	B
	pt1392	4899209107	GQ399632	None		K20R, M36L, I62V, L63P, A71T	B
	pt1267	5604452481	GQ399757	None		M36L, R41K, R57K, L63P, V77I, I93L	B
	pt1265	5612058831	GQ399759	None		L10I, I13V, M36L, N37NS, R57RK, I62IV, L63LP, I64V, A71AV, I93L	B
	pt1157	6246480820	GQ399867	None		M36L, N37S, R41K, R57K, L63P, A71V, V77I, I93L	B
	pt1087	6678219891	GQ399937	None		K20R, M36L, I62V, L63P, A71T	B
	pt613	9329543392	GQ400411	None		I15IV, M36L, N37D, I62V, L63P, I93L	B
	pt412	f06HkNauLA	GQ400612	None		M36L, N37S, I62V, L63LFPS, I64IV	B
Wang (2009)	SH8183	SH8183	FJ469768	None		T12P, L19I, M36L, N37S, L63P, A71V, V77I, I93L	B
Arruda (2010)	1067	16CE091067	JQ230660	None		L19V, M36L, N37S, K43R, R57K, I62V, L63P, I72L	B
	1108	16CE091108R	JQ230686	None		L19V, M36L, N37S, K43R, R57K, I62V, L63P, I72L	B
Brennan (2010)	Pat102	ARC-A131	JN697277	None		G17GE, M36L, N37S, G40GE, R41K, I62V, L63H, I64V	B
	Pat052	ARC-A185	JN697327	None		L33V, M36L, N37A, L63P, I64V	B
Ragonnet-Cronin (2010)	PHAC_347	PHAC_347	HM468845	None		E35D, M36L, N37D, Q61Q*, L63P	B
	PHAC_404	PHAC_404	HM468902	None		T12S, L19I, L33V, M36L, N37S, I64V	B
	PHAC_535	PHAC_535	HM469033	None		K14R, L19I, M36L, I62V, L63C	B
	PHAC_556	PHAC_556	HM469054	None		K14R, L19I, M36L, I62V, L63C	B
	PHAC_597	PHAC_597	HM469095	None		M36L, N37S, I62IV, L63C, L89M	B
	PHAC_777	PHAC_777	HM469275	None		K14R, L19I, M36L, I62V, L63C	B
Yebra (2010)	224147	05SP0224147	FJ481785	None		T12P, L19I, E35D, M36L, N37D, R57K, I62V, L63I, E65D, A71V, I72T, I93L	B
	321469	06SP0321469	FJ481848	None		M36L, N37AGST, L63P, I64V	B
Chibo (2011)	S79	S79	JF895266	None		T12A, L19I, M36L, N37S, I62V, L63Q, I64V	B
de Medeiros (2011)	Pat029	RS101	JF487858	None	V32E, I84L	Q7E, E21G, E35N, M36L, N37S, R41K, L89M	B
Ferreira (2011)	BRMT2864	BRMT2864	HQ638733	None		I13V, M36L, N37S, Q61H, L63P, H69Q, K70E, A71V, T91A, Q92K	B
	BRMT3056	BRMT3056	HQ638740	None		M36L, N37S, K45R, I62V, L63S, I64V, H69Q, K70E, A71V, T91A, Q92K	B
	BRMT521	BRMT521	HQ638762	None		M36L, N37S, K45R, I62V, L63P, I64M, H69Q, K70E, A71V, T91A, Q92K	B
	BRMT522	BRMT522	HQ638763	None		I15V, K20KR, M36L, R41K, R57K, I62IV, L63P, I93L	B
	BRMT1238	BRMT1238	HQ638780	None		I13V, K20R, M36L, D60E, Q61E, I62V, L63LP, I64V	B
Truong (2011)	05003101	05003101		None		I13V, M36L, N37D, L63P, I72IV	B
	07000039	07000039		None		M36L, N37C, R57K, L63P, I64V	B
	06001484	06001484		None		I15V, M36L, I62V, I64L, H69Y, A71V, I72T, I93L	B
	05001481	05001481		None		I15V, M36L, I62V, H69Y, A71V, I72T, I93L	B
	05001841	05001841		None		I15V, M36L, I62V, H69Y, A71V, I72T, I93L	B
Avila-Rios (2012)	JC00MC6GRU	JC00MC6GRU	KC169104	None		T4P, K14R, E35D, M36L, N37D, R41K, L63P, I72IV	B
	JV00MEEOR0	JV00MEEOR0	KC169146	None		G16A, M36L, N37S, I62V, L63S, I64V, V77I, I93L	B
	M000M95GTD	M000M95GTD	KC169195	None		I15V, M36L, N37S, V56L	B
	J000MG1TQL	J000MG1TQL	KC168987	None		M36L, N37S, I62V, L63P, L89M	B
da Silveira (2012)	BRMS03_10	BRMS03_10	JF342314	None		T12K, I15IV, L19IV, M36L, N37S, P39PS, R57K, L63P, I64V	B
De Gascun (2012)	IRL41729	IRL41729	JN622591	None		I15V, L19I, K20R, E35D, M36L, N37D, L63S, Q92K	B
	IRL23656	IRL23656	JN622642	None		T12TP, E35D, M36L, N37E, I62V, L63IT, H69K, A71T, I93L	B
	IRL42604	IRL42604	JN622684	None		I15V, G16A, M36L, N37T, I62V	B
Delwart (2012)	477-3983-6	477-3983-6	JN214988	None		I13V, I15V, L19I, M36L, I62V, L63T, I64L, K70R, I72T	B
	478-4822-3	478-4822-3	JN215022	None		I13V, L19I, M36L, N37H, L63P	B
	479-9378-9	479-9378-9	JN215069	None		M36L, L63S, E65D, I72V, V77I	B
Gaspareto (2012)	LBS41	LBS41PT	HM752172	None		T4S, T12K, I15V, M36L, R41K, Q61N, I62V, L63V, I64M, E65D	B
Ragonnet-Cronin (2012)	A10_030	A10_030	JX014692	None		L10V, I15V, M36L, N37S, R41RK, L63T, I72T	B
	A10_175	A10_175	JX014749	None		L10V, I15V, G16E, M36L, L63T, I72T	B
	A10_187	A10_187	JX014756	None		L10I, I15V, M36L, N37S, L63T, I72T, L89M, I93L	B
	A10_254	A10_254	JX014782	None		L10V, I15V, M36L, N37S, L63T, I72T	B
	A10_370	A10_370	JX014826	None		L10I, I15V, M36L, N37S, R41K, D60E, L63T, I72T, I93L	B
	B07_388	B07_388	JX014945	None		E35D, M36L, N37D, R57RK, I62V, L63S, I64ILM, A71V, I93L	B
Ragonnet-Cronin (2012)	PHAC08_084	PHAC08_084	JQ674820	None		L10I, T12K, M36L, N37D, R41RK, L63P, I93L	B
	PHAC08_089	PHAC08_089	JQ674822	None		I15V, E35EG, M36L, N37X, I62V, L63P, A71T, I72E, V77I, I93L	B
	PHAC08_149	PHAC08_149	JQ674837	None		K14R, L19I, M36L, I62V, L63C, I72IT	B
	PHAC09_099	PHAC09_099	JQ674916	None		M36L, N37T, D60E, Q61E, I62V, I64V, I72V	B
	PHAC09_104	PHAC09_104	JQ674918	None		L10I, K20R, E35DN, M36L, N37D, L63P, A71T, I93L	B
	PHAC08_114	PHAC08_114	JQ675086	None		I15IV, M36L, N37T, R41RK, D60E, Q61E, I62V, I64V, I72V	B
	PHAC08_136	PHAC08_136	JQ675098	None		I15V, M36L, N37A, D60E, Q61E, I62V, L63P	B
	PHAC08_151	PHAC08_151	JQ675103	None		L10I, M36L, N37D, L63PS, I93L	B
	PHAC08_254	PHAC08_254	JQ675159	None		L10I, I15V, M36L, N37S, L63T, I72T, I93L	B
	PHAC08_280	PHAC08_280	JQ675177	None		L10I, T12K, M36L, N37D, R57RK, L63P, I93L	B
	PHAC08_287	PHAC08_287	JQ675182	None		L10I, T12P, I15V, G16GE, E35D, M36L, N37D, P39Q, Q61DN, I62V, L63AT, I93L	B
	PHAC08_302	PHAC08_302	JQ675189	None		I15V, M36L, R41K, I62V, I64IV, A71T, I72V, V77VI, I93L	B
	PHAC08_310	PHAC08_310	JQ675191	None		L10I, I15V, M36L, N37S, R41RK, L63T, I72T, I93L	B
	PHAC09_161	PHAC09_161	JQ675260	None		M36L, N37E, R57K, I62V, L63P, A71V, I93L	B
Alencar (2013)	RJ2-0024	RJ2-0024	JQ237946	None		I15V, M36L, N37T, I62V, L63P, I72T	B
	MG2-0018	MG2-0018	JQ238018	None		T12P, K14R, L19I, M36L, L63P, C67Y, A71V, I72V, V77I, I93L	B
	PE2-0039	PE2-0039	JQ238030	None		I15V, M36L, N37S, I62V, L63P, H69HQ, I72IT	B
	PE2-0040	PE2-0040	JQ238054	None		I15V, M36L, N37S, I62V, L63P, I72T	B
	PE2-0091	PE2-0091	JQ238158	None		L10V, I13V, M36L, R41K, D60E, L63P, I64V	B
	RJ2-0105	RJ2-0105	JQ238217	None		K14R, I15V, L19T, M36L, N37S	B
Ferreira (2013)	BR09SP205	BR09SP205	HM534120	None		Q2QP, T12P, L19LI, M36L, N37E, D60E, I62V, L63P, I64V, I93L	B
Frentz (2013)	EHR-11420	EHR-11420	JX299721	None		I13V, I15V, L19I, K20R, M36L, N37S, R57K, L63S, I64V, V75VI	B
	EHR-149859	EHR-149859	JX299788	None		M36L, N37S, L63S, A71V, I72T, V77I, I93L	B
	EHR-16230	EHR-16230	JX299811	None		M36L, N37S, L63S, A71V, I72T, V77I, I93L	B
	EHR-33768	EHR-33768	JX300112	None		L10I, M36L, N37S, I62V, L63S, I64V, I93L	B
	EHR-38665	EHR-38665	JX300189	None		L10I, M36L, N37S, I62V, L63S, I64V, I93L	B
	EHR-48968	EHR-48968	JX300353	None		T12P, L19I, M36L, N37S, R41RK, Q61QHKN, L63S, I64V, E65D, I93IL	B
	EHR-59489	EHR-59489	JX300532	None		M36L, N37T, I62V, L63S, I64V	B

Protease Inhibitors

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