<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype B
Gene PR
Mutation L24F
Rx >= 1 PI
IncludeMixtures No
References 12
Patients 64
Isolates 70
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Balotta (2000)CB-151CB-151AF252015SQV, RTV, IDV M46L, I84V, L90M L10I, L24F, E35D, M36I, I62V, L63P, I64V, A71V, V77I, N88NY, I93LB
Gonzales (2001)CA6437CA16211AY032390SQV, NFV164M46I, L90MG73STL10I, L24F, N37C, K45R, K55R, R57K, L63P, A71V, V77I, I93LB
Margot (2002)MM-3571368123571368121 PINAM46I, I84V, L90M L24F, M36I, N37D, I62V, L63P, A71V, I72V, T80TA, I93LB
Romano (2002)MZ-pt41pt41-t1AF493415IDV, RTV, LPV M46I, I54V, V82A, L90MG73SL10I, I15V, L19V, K20I, L24F, M36I, L63P, H69K, A71V, I93LB
Wu (2003)CA4914CA12111AF544578NFV, SQV, RTV, IDV68M46I, I54V, V82T, L90M L10I, L24F, N37D, L63P, A71V, V77I, I93LB
Colonno (2004)RC-009-007-064007-06421 NFV, SQV, ATV60M46I, I84V, L90ML23I, F53L, G73TL10X, I13V, K14R, I15V, G16A, L24F, E35D, N37X, I62V, L63P, I64V, I72X, V77I, I93L, C95FB
Gomez-Carrillo (2004)103277103277AY365674PINAM46I, I54V, V82A, L90ML33F, F53FL, G73SL10V, G16A, L24F, E34EQ, K45KR, K55H, Q61E, L63P, A71V, I72K, I93LB
 121150121150AY365998PINAI54V, L90ML33F, F53L, G73SI13V, L24F, L63P, A71V, V77IB
Rhee (2005)CA799CA21348AY796485RTV, IDV, SQV, NFV, Unknown, LPV, APV>210I54V, V82A, L90ML33F, G73S, L89LVL10I, I15V, K20V, L24F, E35DN, M36I, R57K, I62V, L63P, A71V, I72MB
 CA1502CA37835AY796742RTV, NFV, Unknown>222M46L, I54V, V82A, L90M L10I, I15V, L19I, K20R, L24F, M36I, R41K, L63P, A71V, I93LB
 CA5126CA23963AY797239IDV, APV242M46L, L90ML33F, G73S, L89VL10I, I13V, L24F, I62V, L63P, V77I, V82I, I93LB
 CA6437CA24640AY797405SQV, NFV, RTV, IDV230M46I, L90MG73TL10I, L24F, N37C, K45R, K55R, R57K, L63P, A71V, I72IT, V77I, I93LB
  CA37913AY797406SQV, NFV, RTV, IDV290M46I, L90MG73TL10I, L24F, N37C, K45R, K55R, R57K, L63P, A71V, I72T, V77I, I93LB
 CA8097CA20645AY797700RTV, NFV185M46L, I54V, V82A, L90ML33FI13V, L24F, I62IV, L63P, A71V, V77I, I93LB
  CA42697AY797701RTV, NFV343M46L, I54V, V82A, L90ML33F, K43KTI13V, L24F, I62IV, L63P, A71IV, V77I, I93LB
 CA14690CA34128AY798151Unknown, SQV, RTV>32M46I, I84V, L90M L10I, L19V, L24F, F53Y, L63P, A71V, I72V, V77I, Q92R, I93LB
Baxter (2006)12-16961696-30429DQ875996PINAM46I, I54V, V82A, L90ML33F, F53LL10I, L24F, E35ED, N37E, I62V, L63P, A71I, I93LB
 12-11201120-30319DQ876011PINAM46I, L90MG73CL10I, K14KR, K20I, L24F, I62V, L63P, A71V, I72V, T74S, V77I, I93LB
 12-12491249-30304DQ876080PINAM46L, I54L, V82A, L90ML10F, L33F, K43TI13V, L24F, K55R, I62V, L63P, A71V, V77I, L89I, I93LB
 12-40504050-30820DQ876156PINAI54V, I84V, L90ML10F, G73SI15V, L19P, K20V, L24F, E34Q, M36I, N37D, I62V, L63P, A71V, I72L, P79D, I93LB
 12-16461646-30403DQ876199PINAM46I, I54V, V82A, L90ML33F, G73TL10I, I13V, L19LV, K20R, L24F, E35D, M36I, K55N, I62V, L63P, A71V, I72K, V77I, I93LB
 12-10531053-30402DQ876310PINAM46L, I54V, I84V, L90ML33F, G73TL10I, K20R, L24F, E35D, M36I, N37D, K43Q, I62V, L63P, I64V, A71V, I72R, P79AB
 12-10781078-30409DQ876401PINAV32I, M46L, I54V, V82A, L90ML33F, T74PL10I, I13V, G16A, K20R, L24F, M36I, K55R, I62V, L63P, I66V, G73V, I85LB
 12-16281628-30416DQ876523PINAM46L, I54V, V82A, L90ML33F, F53LL10V, G16A, L24F, R41K, L63P, I64L, A71V, I72V, V77I, T91S, I93LB
 12-24942494-30821DQ876595PINAM46L, I54V, V82A, L90MV11VI, L33F, F53L, G73TL10I, I13V, G16A, K20R, L24F, M36MIL, R41K, K55R, I62V, L63P, A71V, I72TB
 12-14691469-30422DQ876874PINAI54IV, V82A, L90MV11IL, L33F, F53LL10I, I15V, K20V, L24F, E35N, M36I, R41K, K45KR, K55KR, D60E, I62V, L63P, A71I, I85IV, L89LIMB
 12-19491949-30528DQ876913PINAM46I, V82T, I84V, L90ML10F, L33F, G73SI13V, L24F, I62V, L63P, A71V, I72VB
 12-30963096-30513DQ877196PINAI54V, V82C, L90ML10F, G73SI13M, I15V, G17E, K20V, L24F, M36I, N37D, K43KR, R57K, D60E, I62V, L63P, A71V, I72RB
 12-30633063-30325DQ877224PINAM46I, I47A, I84V, L90ML33I, G73GSL10I, L24F, N37D, K45R, I62V, L63P, A71V, I72L, V77I, I93LB
 12-32133213-30818DQ877252PINAM46I, I54V, I84V, L90ML33F, G73TL10IT, G16A, L24F, Q61H, I62V, L63P, I66IV, A71V, I72IL, V77I, I93LB
 48-10111011-30610DQ877314PINAM46L, I54L, V82A, L90ML33F, Q58EL10I, I13IV, K20R, L24F, E35D, M36I, N37D, R41K, D60E, I62V, L63P, A71V, I93LB
 48-10641064-30611DQ877315PINAM46IL, I54V, V82A, L90MV11VI, L33F, K43T, G73SL10I, I13V, L24F, E34Q, K55R, D60E, I62V, L63P, A71V, I72K, V77I, I93LB
 48-12561256-30515DQ877782PINAM46L, I54V, V82A, L90ML10F, L33F, K43T, F53LT4P, I13V, I15V, L19LI, K20R, L24F, E35D, M36I, R41K, L63P, A71I, Q92K, I93LB
 48-14351435-30318DQ877824PINAM46L, I54V, V82A, L90MG73SL10I, I15V, G16A, L19I, K20R, L24F, E35ED, M36I, R41K, I62V, L63P, A71V, I93LB
 48-26222622-30908DQ877910PINAV32I, M46I, I47V, I54M, V82A, L90MV11I, L33F, G73S, L89VL10V, I13V, L24F, N37D, K45R, L63P, A71I, V77I, I93LB
 48-31063106-30425DQ878012PINAM46L, I54V, V82C, L90ML10F, L33I, Q58EK20R, L24F, E35D, M36I, N37DE, K55R, R57K, I62IV, L63P, A71V, I93LB
 48-31843184-30429DQ878092PINAM46L, I54V, V82A, L90ML33F, Q58E, G73STL10I, I13V, K20R, L24F, E35D, M36I, N37D, K55R, R57RK, I62V, L63P, A71V, I72ITB
 48-32053205-30612DQ878115PINAM46L, I54V, V82A, L90MQ58EL10I, L19Q, K20R, L24F, E35D, M36I, R41K, R57RK, D60X, I62V, L63P, A71V, I93LB
 48-32373237-30521DQ878144PINAM46I, I54L, V82A, L90ML33F, G73TL10I, I13V, L24F, R41K, K55R, I62V, L63P, A71I, I72V, V77I, I93LB
 48-32783278-30910DQ878185PINAM46I, I54V, V82A, L90ML33F, F53L, G73SL10I, I13V, G16A, L24F, N37D, Q61H, L63P, I64IM, A71V, I72L, I93LB
 48-40024002-30311DQ878235PINAM46L, I54V, V82A, L90ML33F, G73SL10I, I13V, L24F, I62V, L63P, A71V, I72T, V77IB
 48-41204120-30403DQ878351PINAM46L, I54V, V82A, L90ML33F, K43T, F53L, T74PL10I, I13V, L24F, I62V, L63P, A71V, V77I, I93LB
 48-41324132-30320DQ878363PINAM46I, I54V, V82A, L90ML33F, G73SL10I, I13V, K14KR, L19I, K20R, L24F, E35D, M36I, N37D, I62V, L63P, A71V, I93LB
 48-41744174-30502DQ878408PINAM46L, I54V, V82A, L90ML33F, G73SL10I, I13V, L24F, I62V, L63P, A71V, I72T, V77IB
 48-41974197-30522DQ878430PINAM46L, I54V, V82A, L90ML33F, Q58E, G73SL10I, I13V, G16A, L24F, K55R, I62V, L63P, A71V, I72MB
 48-42004200-30515DQ878432PINAM46L, I54L, V82A, L90ML10F, L33F, K43T, F53L, G73AG16A, L19I, L24F, E34Q, K55R, D60E, I62V, L63P, I64M, A71I, I72L, I93LB
 48-42144214-30507DQ878447PINAM46L, I54V, V82A, L90ML23I, L33F, Q58E, G73GS, T74TPL10I, I13V, L24F, I62V, L63P, A71V, I93LB
 48-50135013-30513DQ878548PINAM46I, I54V, V82A, L90MQ58E, G73SL10I, I15V, G16A, L19P, K20M, L24F, M36V, K55KR, R57K, D60E, I62V, L63P, A71V, I72LB
 48-60076007-30226DQ878603PINAM46L, I54V, V82A, I84V, L90ML33F, K43TL10I, I13V, I15V, K20R, L24F, E35D, M36I, N37D, R57K, Q61N, I62V, L63A, A71V, Q92KB
 48-60246024-30407DQ878623PINAM46L, I54V, V82A, L90ML33F, Q58E, G73GSL10V, T12I, I13V, L24F, N37D, K55R, D60E, L63P, A71V, V77I, I93LB
 48-72027202-30808DQ879027PINAI54V, V82A, L90MV11VI, F53LL10I, I15V, K20I, L24F, E35D, M36I, R41K, D60E, I62V, L63P, A71I, I72LB
 48-93109310-30923DQ877295PINAM46I, L90ML33F, Q58QE, G73SL24F, N37D, L63P, A71V, I72R, V77I, I93LB
 48-90389038-30901DQ877505PINAM46L, I54V, V82A, L90ML33F, G73SL10I, G16A, L24F, K55R, R57K, D60E, I62V, L63P, A71V, I72LB
 48-91999199-30910DQ877575PINAM46L, I54V, V82A, L90MG73SL10I, I15V, G16A, K20M, L24F, E35D, M36I, R41K, K55R, I62V, L63P, A71V, I72LB
 48-90169016-30908DQ877628PINAI54V, V82A, L90ML33F, K43KPQT, G73TL10I, I13V, G16A, L24F, E34Q, R57K, Q61E, I62V, L63P, A71T, I72T, I93LB
 48-90919091-30827DQ877652PINAM46L, I54V, V82A, L90MV11I, L33F, Q58E, G73S, L89VL10I, I13V, L24F, N37D, K55R, D60DN, I62V, L63P, K70KN, A71I, I72M, V77I, C95LB
 48-91029102-30908DQ877691PINAM46I, I54V, I84V, L90MG73SL10I, Q18H, L19P, K20I, L24F, L33V, M36I, N37S, I62V, L63P, H69L, A71T, I72R, I93MB
 48-91229122-30930DQ877710PINAI54V, V82A, L90ML33F, K43KT, F53L, G73SL10I, I13V, I15V, K20R, L24F, E35D, M36I, K55R, I62V, L63P, A71V, I72VB
 48-80068006-30527DQ879051PINAM46L, V82A, L90ML10F, Q58E, G73S, L89VI15V, Q18H, K20I, L24F, R41K, L63P, A71V, I72ILM, I93LB
Rosen-Zvi (2008)7703p77-2 SQV, IDV, NFV, RTV, APV, LPV252M46I, I84V, L90ML33F, G73SL5F, L10I, L24F, E34Q, R41K, F53Y, I62V, L63P, A71V, I72K, V77I, I93LB
  05p77-3 SQV, IDV, NFV, RTV, APV, LPV368M46I, I54IL, I84V, L90ML10F, L33F, G73SL5F, I13IM, G16A, L24F, E34Q, R41K, F53Y, I62V, L63P, I64IM, A71L, I72K, V77I, I93LB
  06p77-4 SQV, IDV, NFV, RTV, APV, LPV429M46I, I54L, I84V, L90ML10F, L33F, G73SL5F, I13V, G16A, L24F, E34Q, R41K, F53Y, I62IV, L63P, I64IM, A71L, I72K, I93LB
  07p77-5 SQV, IDV, NFV, RTV, APV, LPV475M46I, I54L, I84V, L90ML10F, L33F, G73SL5F, I13V, G16A, L24F, E34Q, R41K, F53Y, I62IV, L63P, I64IM, A71L, I72K, I93LB
Dau (2010)09214A09214AGU581958PINAM46L, I54V, V82A, I84V, L90ML33F, Q58E, G73SP9PL, L10I, I13V, K20R, L24F, T31TI, E35DN, M36I, N37EQ, K55R, R57K, D60E, I62V, L63P, A71V, I72TB
 10017A10017AGU581991PINAM46I, I54L, V82A, L90ML33F, K43T, G73ST4S, L10V, I13IV, I15V, G16A, L24F, I62V, L63P, A71I, I72R, V77VI, I93LB
Jones (2012)129273129273JN669462PINAM46I, I54V, I84V, L90ML10F, G73TI13V, I15V, Q18H, K20V, L24F, L33LM, M36L, N37P, Q61H, I62V, L63P, I66V, A71T, I72T, V77I, I93LB
 140263140263JN669586PINAM46I, I54V, I84V, L90ML33LI, G73TL10I, T12TP, G16GA, L24F, E35D, M36ML, N37D, K55KR, I62V, L63P, H69HR, A71IT, I72K, V77I, I93LB
 172184172184JN670281PINAM46I, I54V, V82A, L90ML33F, G73STL10I, I13V, L24F, E35ED, M36MV, N37NT, R41K, K55R, R57RK, I62V, L63P, A71V, I93LB
 178086178086JN670469PINAM46L, I54V, V82A, L90ML33F, K43T, G73SL10I, I13V, I15IV, L19LS, K20R, L24F, E35D, M36I, R41K, K55R, R57K, Q61N, I62IV, L63P, I66V, K70KT, A71V, I72IT, I85L, I93LB
 196990196990JN671051PINAM46I, I54V, V82A, L90ML33F, G73SL10I, I15V, K20R, L24F, E35D, M36L, N37D, K55R, R57K, I62V, L63P, H69K, A71V, I72FL, V77IB