<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype B
Gene PR
Mutation L23I
Rx >= 1 PI
IncludeMixtures No
References 25
Patients 176
Isolates 189
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Balotta (2000)CB-131CB-131AF252001PINAM46L, I54V, V82A, I84V, L90ML23I, Q58EQ2K, L10I, E35D, M36I, L63P, A71V, I93LB
Shulman (2000)CA1158CA11021AY798381IDV, SQV, NFV, RTV127I54V, V82A, L90ML23I, F53LL10I, E35D, M36V, R57K, D60E, I62V, L63P, A71V, I93LB
 CA1277CA4390AY798386IDV, NFV64 L23IK20KR, N37T, L63P, T74S, V77VI, V82I, I93LB
Gonzales (2001)CA1435CA3837AY030573IDV, SQV, RTV, NFV103V32I, M46I, V82A, L90ML23I, F53LL10V, T12S, L19Q, M36L, N37S, I62V, L63P, A71VB
 CA1800CA4836AY030718RTV, SQV120M46ML, I54V, V82A, I84IV, L90ML23IL10I, R41RK, R57K, L63P, A71VB
 CA1809CA4855AY030724NFV85 L23II13V, K14R, I15V, K20T, E35G, R41K, I64V, V77I, V82I, I93LB
 CA3910CA9686AY030913SQV, NFV, RTV162M46L, I54V, V82A, I84V, L90ML23IL10I, P39A, L63P, A71V, V77IB
 CA5750CA14288AY032140IDV, SQV, RTV157M46I, L76V, I84V, L90ML23I, F53LL10I, E35D, N37D, D60E, L63P, I64V, A71V, I93LB
Chantratita (2002)G23G23AF193891PINAM46I, L90ML23IL10I, I15V, N37D, D60E, L63A, I64V, T74A, Q92KB
Tural (2002)880418880418 RTV, IDV, SQV, NFV143I54V, V82A, L90ML23I, F53LL10V, I15V, K20R, M36I, N37D, R41K, I62V, L63P, I93LB
 880423880423 IDV, NFV, SQV120M46I, I54V, V82F, L90ML23IL10I, E35D, N37D, R41K, F53Y, L63P, A71T, I72V, V77I, Q92R, I93LB
 880814880814 SQV, NFV85M46I, L90ML23I, F53L, G73SL10I, K20I, N37H, R41K, L63P, A71V, V77IB
 881505881505 IDV, SQV, RTV138M46I, L76V, I84VL23I, F53LL10I, I13V, I15V, L19V, K20R, M36I, I62V, L63P, I64VB
Wu (2003)CA1277CA10012AF544453IDV, NFV70 L23IN37T, L63P, T74S, V77I, V82I, I93LB
 CA3910CA20414AF544536SQV, NFV, RTV219M46L, I54V, V82A, I84V, L90ML23IL10I, P39A, D60DE, I62IV, L63P, A71V, V77IB
 CA8022CA20534AF544609SQV310I54V, L90ML23I, N88DL10I, I13V, M36MI, N37ND, L63P, A71V, I72V, T74SB
 CA8355CA21281AF544615RTV, IDV, SQV, APV316V32I, M46I, I47V, I54V, L90ML23I, L33I, F53L, G73CL10I, E35D, M36I, I62V, L63P, I64V, I66L, A71X, I72MV, I93LB
 CA9429CA23150AF544618NFV202M46I, L90ML23ID60E, I62V, L63N, I64V, I72T, V77I, V82I, I93LB
Colonno (2004)RC-009-014-023014-02321 NFV, SQV, ATV68M46I, I84V, N88SL23IL10I, I13V, E35D, N37Y, R41K, L63X, A71T, V77I, L89MB
 RC-810024D24D11 NFV D30NL10F, L23I, N88DI13V, N37S, R41K, I62V, L63P, K70R, A71T, I93LB
 RC-009-007-064007-06421 NFV, SQV, ATV60M46I, I84V, L90ML23I, F53L, G73TL10X, I13V, K14R, I15V, G16A, L24F, E35D, N37X, I62V, L63P, I64V, I72X, V77I, I93L, C95FB
Rhee (2004)CA9752CA41282AY798494NFV111 L23I, Q58QEE35D, R41K, L63P, V77I, V82I, I93LB
Garcia-Bujalance (2005)GBS_45GBS_45AY872326SQV, RTV, LPV M46L, I54V, V82A, I84V, L90ML10FI, L23I, L33F, Q58EI13IV, E34EQ, I62V, L63P, A71V, I72VB
 GBS_04GBS_04AY872285RTV, NFV135M46LL23II13V, I15V, K20T, M36I, L63P, H69K, A71T, L89I, Q92RB
Non-B Workgroup (2005)TK2028TK2028 IDV, SQV, RTV207M46MI, I54V, L90LML23I, F53L, N88NDK14KR, E35ED, N37P, L63P, A71AVB
Rhee (2005)CA628CA17003AY796444SQV, IDV, RTV, Unknown, APV>152M46L, V82A, I84V, L90ML23I, Q58EL10I, D60E, Q61EK, L63P, A71T, I72TB
 CA1158CA33933AY796531IDV, SQV, NFV, RTV, APV, LPV214I54V, V82A, L90ML23I, L33F, F53LL10I, E35D, M36V, R57K, D60E, I62V, L63P, A71V, I93LB
 CA1263CA41214AY796570IDV, SQV, RTV427L90ML23I, F53L, G73SL10I, I62V, L63P, H69HY, A71T, V77I, I85VB
 CA1800CA13472AY796814RTV, SQV, Unknown>120M46L, I54V, V82A, I84V, L90ML23IL10I, R57K, L63P, A71V, Q92KB
 CA2251CA33641AY796909IDV, NFV238M46IL23I, L76EL10I, I13V, E35D, N37D, Q61N, I62IV, L63P, I64V, V77IB
  CA37811AY796910IDV, NFV288M46IL23I, L76EL10I, I13V, E35D, N37D, Q61N, I62V, L63P, I64V, V77IB
 CA5175CA37858AY797256IDV, SQV, RTV319V32I, M46L, I54V, V82A, L90ML23I, L33F, F53LI13V, K14R, K20R, M36I, L63P, I64V, A71VB
 CA5204CA33687AY797264NFV, SQV, RTV184I84V, L90ML23I, N88DG16A, K20R, M36I, R57K, Q61H, L63P, H69Q, A71I, I93MB
 CA8022CA24065AY797651SQV325I54V, L90ML23I, N88DL10I, I13V, M36I, N37D, L63P, A71V, I72V, T74SB
 CA8355CA33974AY797717RTV, IDV, SQV, APV, LPV398V32I, M46I, I47V, I50V, I54V, L90ML23I, L33I, F53L, G73CL10I, K20R, E35D, M36I, I62V, L63P, I64V, I66L, A71I, I72V, I93LB
 SWC-3636P3636-2284 NFV, SQV, RTV65M46L, L90ML23I, G73TL10I, T12E, L19I, M36I, I62V, L63P, R87K, I93LB
 CA9429CA33310AY797775NFV, Unknown>202M46I, L90ML23IL10LI, D60E, I62V, L63N, I64V, I72T, T74TS, V77I, V82I, I93LB
 CA17599CA41438AY798266RTV, IDV, LPV330M46L, I54V, L76V, V82AL23IL10I, I15V, I62V, L63V, H69R, A71V, I72K, L89M, I93LB
Baxter (2006)12-16261626-30328DQ875995PINAM46L, I54V, V82A, L90ML23IL10I, T12TS, K20R, M36MI, N37D, I62V, L63P, A71V, Q92R, I93LB
 12-19151915-30714DQ876008PINAM46I, I54V, L90ML10F, L23I, L33F, F53L, G73ST12E, R41K, Q61R, I62V, L63P, C67Y, A71V, I72L, V77VI, I93LB
 12-11721172-30415DQ876058PINAM46L, I54V, V82A, L90ML23I, L33F, Q58E, G73SL10I, N37T, D60E, I62V, L63P, A71V, I72K, I93LB
 12-40044004-30128DQ876161PINAM46I, I54V, L76V, V82AL23I, F53LL10I, R41K, D60E, I62V, L63P, A71V, I93LB
 12-20072007-30604DQ876238PINAV32I, I54V, L90ML23I, L33LI, M46V, F53L, Q58E, G73SL10I, I13IV, K20R, E35D, M36I, N37S, R57K, I62IV, L63P, I64V, A71V, V82IB
 12-22372237-30715DQ876249PINAM46I, I54V, L76V, V82F, L90ML23I, L33F, K43TL10I, I13V, E35D, M36I, N37NS, I62V, L63P, I64V, A71AV, I93LB
 12-23192319-30819DQ876417PINAI54V, V82A, I84V, L90ML23I, L33F, G73SL10I, I15V, N37Y, I62V, L63P, A71V, I72LB
 12-10831083-30429DQ876423PINAM46L, I54V, V82T, L90ML10F, L23I, L33F, K43T, F53LK20R, E35D, M36I, K55R, I62V, L63P, A71V, I93LB
 12-22172217-30730DQ876459PINAM46L, I54V, V82A, L90ML10F, L23I, K43T, Q58EI15V, K20R, E35D, M36I, N37D, I62V, L63P, A71V, I93LB
 12-19201920-30529DQ876481PINAV32I, I47V, I54M, V82A, L90ML23I, L33F, K43T, G73S, L89VL10I, K14R, G16R, E34Q, E35D, M36L, N37D, I62V, L63P, A71L, I72L, V77I, I93LB
 12-13531353-30711DQ876492PINAM46L, I54V, V82A, L90ML23I, L33F, Q58EL10I, I13V, L19I, L24M, M36ML, N37D, K55R, I62V, L63P, H69Y, A71T, I72T, V75IB
 12-23592359-30814DQ876599PINAL90ML23I, G73SL10I, K45R, R57K, L63P, A71V, V77VI, I93LB
 12-14071407-30507DQ876789PINAM46L, I54V, L76V, V82A, I84IV, L90ML23I, L33FL10I, I13V, G16GA, L63P, H69Y, A71V, I72V, V77I, I93LB
 12-11521152-30701DQ876894PINAM46I, I50VL10F, L23I, L33F, F53L, G73GSI13V, G16GA, N37ND, L63P, V77I, I93LB
 12-11701170-30305DQ876942PINAI54V, V82A, L90ML23I, K43T, F53L, N88DL10I, K20R, E35D, M36I, R57K, I62V, L63P, A71VB
 12-19581958-30606DQ876990PINAI54V, L76V, V82FL23I, L33I, Q58EL10I, Q18E, K20KR, E34D, E35D, M36I, N37C, I62V, L63P, H69R, L89MB
 12-12601260-30318DQ877128PINAM46L, I54V, L76V, V82AL23I, Q58EL10IV, I15V, G16GA, L63A, A71V, I93LB
 12-30673067-30402DQ877206PINAM46I, L76V, V82F, L90ML23I, L33F, Q58EI13V, E35D, M36I, N37D, I62V, L63Q, I64VB
 12-30353035-30310DQ877215PINAI54V, V82A, L90ML23I, F53FLL10I, N37NS, R41RK, D60E, I62V, L63P, I64L, A71T, I72IV, V77I, I93LB
 12-31023102-30610DQ877250PINAL90ML23I, L33F, F53L, Q58EL10I, T12P, I15V, G16E, L19V, K20R, E35D, M36I, N37T, I62V, L63T, H69K, T74A, V82I, I85V, L89M, I93LB
 48-10441044-30617DQ877367PINAM46I, L76V, V82T, L90ML23I, F53L, Q58EL10I, I15V, K20R, E35D, M36I, N37D, K55R, R57K, D60E, I62V, L63P, A71V, I93LB
 48-11151115-30716DQ877380PINAM46I, I50IV, I54IM, V82A, L90ML23I, L33F, K43T, F53FLT4S, L10I, L63P, H69Q, A71V, I85IV, I93LB
 48-12471247-30610DQ877770PINAM46I, I54V, L76VL23I, L24I, F53L, Q58EL10I, T12P, L19LI, N37S, I62V, L63Q, I64V, H69R, A71V, V77I, L89M, I93LB
 48-26172617-30630DQ877907PINAI54V, V82A, I84V, L90ML23I, K43TL10I, T12E, L19V, K20R, E35D, M36IV, I62V, L63P, H69Q, A71I, Q92K, I93MB
 48-30033003-30225DQ877913PINAM46MI, I54V, V82A, I84VL23I, L24LI, F53FLL10I, I15V, G16GE, L19V, K20M, E35D, M36I, R41RK, K45N, K55KR, Q61QH, I62V, L63T, I64V, E65D, I72V, I85IV, T91SB
 48-30203020-30303DQ877930PINAM46I, I54L, L76V, L90ML10F, L23I, L33F, Q58E, G73S, L89VI13V, K20A, E34Q, E35D, M36I, K55R, R57K, I62V, L63P, A71V, I72LB
 48-30443044-30306DQ877956PINAM46L, I54V, V82A, I84V, L90ML23I, L33F, Q58E, T74PL10I, I13V, K14KR, G49GE, L63P, A71V, I93LB
 48-30723072-30326DQ877981PINAG48V, I54V, V82S, L90ML23I, Q58EL10I, I15V, K20R, M36I, N37D, G52GV, I62V, L63PB
 48-31163116-30321DQ878024PINAM46I, I50V, I54V, V82A, L90ML23IL10I, E35ED, M36V, N37D, R41K, L63P, A71V, I93LB
 48-31263126-30409DQ878034PINAM46L, I54V, V82A, L90ML23I, K43TL10I, T12P, I15V, D60E, I62V, L63P, L89LM, T91TS, Q92RB
 48-31283128-31125DQ878038PI, RTV, TPV>32M46MIL, I47IV, I54V, V82L, L90ML23I, F53LL10V, I13V, K20R, E35D, M36V, N37E, R57K, D60DE, I62V, L63P, A71IV, V77I, I93LB
  3128-40708DQ878037PI, RTV, TPV>64M46IL, I47IV, I54V, V82L, L90ML23I, F53FL, Q58QEL10V, I13V, K20R, E35D, M36V, N37E, R57K, D60DE, I62V, L63P, A71IV, V77I, L89LM, I93LB
 48-31753175-30422DQ878084PINAM46L, I54V, V82F, L90MV11I, L23I, L33F, F53LL10I, I13V, K43S, I62V, L63P, A71V, I72V, T74A, V77I, I93LB
 48-32253225-30521DQ878132PINAM46L, I54V, V82A, L90ML23I, L33F, K43T, F53L, T74PL10I, I13V, L19I, K20R, E35D, M36I, N37T, K55R, I62V, L63T, C67E, I72T, L89MB
 48-32543254-30610DQ878158PINAV32I, M46I, I47A, L90ML23I, F53FLL10I, I15V, K20T, E35N, M36I, N37D, I62V, L63P, I66IV, A71L, I72V, V77I, I93LB
 48-32733273-30701DQ878178PINAM46I, I54V, L76V, V82AL23I, Q58EL10I, I15V, K20R, M36I, R41K, G51A, L63P, H69R, A71V, I93LB
 48-32863286-30707DQ878192PINAM46I, I54V, L76V, V82F, L90ML23I, F53L, Q58EL10I, K14R, I15V, I62V, L63P, A71V, I93LB
 48-32943294-30729DQ878199PINAM46L, I54V, L76V, V82F, L90ML23I, L33F, Q58EL10I, I13V, K14KR, D60DN, Q61QH, L63P, C67DE, A71AV, V77I, L89M, I93LB
 48-40784078-30225DQ878307PINAM46L, I54L, V82F, I84V, L90ML23I, L33FL10V, I13V, L19V, E35D, M36L, N37D, F53FY, Q61QE, I62V, T74E, L89MB
 48-41554155-30327DQ878389PINAM46I, I47V, I54V, V82AL10F, L23I, F53LR41K, I64V, A71V, I93LB
 48-41964196-30519DQ878429PINAM46L, I54V, V82A, L90ML23I, K43T, F53FL, Q58EL10I, L63P, A71V, I93ILB
 48-42144214-30507DQ878447PINAM46L, I54V, V82A, L90ML23I, L33F, Q58E, G73GS, T74TPL10I, I13V, L24F, I62V, L63P, A71V, I93LB
 48-42484248-30617DQ878481PINAV32I, M46I, I47V, I54L, L90ML23I, L33F, F53L, G73CI13V, E35D, M36L, L63P, A71AT, I72IT, V82I, I93LB
 48-42564256-30715DQ878488PINAM46I, I54V, V82F, L90ML23I, F53FL, Q58EL10I, K20R, E35D, M36I, K55R, R57RK, I62V, L63P, I64IL, I66V, H69HR, A71T, I72V, V77I, I93L, C95FB
 48-60716071-30604DQ878669PINAM46I, L76V, V82F, L90ML23I, L33FL10I, T12K, I13V, K14KR, I62V, L63P, T74A, V77I, L89MB
 48-60886088-30603DQ878683PINAM46I, I54V, L76V, V82F, I84V, L90ML23I, L33F, G48E, Q58EL10I, I13V, E34K, N37T, I62V, L63P, V77I, L89MB
 48-61086108-30930DQ878700PINAM46L, G48A, I54V, V82AL23I, F53L, Q58EL10I, I15V, K20R, E21K, E35D, M36I, N37D, K55R, R57K, I62V, L63V, G68E, H69K, A71V, I93MB
 48-61186118-30923DQ878704PINAM46I, I50V, I54V, V82A, L90ML23I, L33F, K43KT, N88DL10I, I13V, E34Q, M36MI, I62V, L63P, A71V, I72M, C95FB
 48-61216121-30807DQ878707PINAM46I, I54V, L76V, V82A, L90ML23IL10I, T12P, K55R, R57K, D60E, Q61E, I62V, L63P, A71V, I93LB
 48-62266226-30730DQ878793PINAM46L, I54V, L76V, V82F, L90ML23IL10I, I15V, D60E, I62V, L63P, A71V, I93LB
 48-70047004-30805DQ878892PINAM46L, I54V, V82AL23I, L24I, F53LL10I, I15L, L19V, R41K, K55R, L63P, A71I, T74S, V77IB
 48-70647064-30729DQ878932PINAM46I, I50V, I54V, L90ML10F, L23I, G73S, L89VI15V, K20V, E35D, M36I, N37D, D60E, Q61H, L63P, A71V, I72M, I85V, Q92K, I93LB
 48-93149314-30922DQ877646PINAM46L, I54V, V82A, L90ML23I, Q58ER8Q, L10V, L19I, E35D, M36I, N37S, R41K, I62V, L63P, A71V, I72IV, I93LB
 48-93189318-30923DQ877647PINAM46I, I54V, L76V, V82F, L90ML23I, Q58EL10I, K14R, K20R, E35D, M36I, N37D, I62V, L63P, I64V, A71V, I93LB
Rhee (2006)CA1834CA63811 RTV, NFV, IDV, APV, LPV, ATV450I54V, L76V, V82AL10F, L23I, L33F, Q58EI13V, R57K, D60E, L63P, A71V, I93LB
Rosen-Zvi (2008)1700p17-1 SQV, IDV, NFV, RTV199M46I, L90ML23I, F53L, G73SL10I, I13V, I15IV, K20KR, I62IV, L63P, H69R, A71V, V77IB
  01p17-3 SQV, IDV, NFV, RTV, APV257M46I, I54M, L90ML23I, L33F, F53L, G73SL10I, I13V, I15V, K20R, L63P, H69R, A71V, V77IB
Waleria-Aleixo (2008)08RJ06060608RJ060606FJ591766PINAL90ML23II13V, K20T, E35G, M36I, R41K, I62V, L63HQ, I64V, T74S, V82I, I93ILB
 RG35RG35FJ592044PINAM46I, L90ML10FI, L23I, Q58EI13V, L63P, A71V, I72T, V77I, V82I, I93LB
 08PR05036608PR050366FJ591391PINAM46L, I54T, V82A, L90ML23I, L33F, T74PL10I, I13V, R41K, K55KR, I62V, L63P, I66F, A71V, V77VIB
 08RJ06068908RJ060689FJ591803PINAM46L, I54V, V82AL23I, F53LL10I, I15V, K55RB
Banke (2009)2288u2288uGQ334976PINAM46L, I54V, V82A, L90ML23I, F53L, N88DL10I, I15IV, K20X, E35ED, N37P, K45R, D60E, I62IV, L63P, I66IF, A71V, T91TSB
Rhee (2009)CA5204CA50796FJ983179NFV, SQV, RTV, LPV304I84V, L90ML10LF, L23I, N88DI13IV, G16A, K20R, M36I, R57K, Q61H, L63P, H69Q, A71I, I93MB
Dau (2010)06497A06497AGU581753PINAM46I, I50V, L76V, L90ML23IK14R, I15V, K20R, E35D, M36I, N37E, R41K, I62V, L63P, I64V, A71V, V82I, I93LB
 06725B06725BGU581775PINAI54V, V82A, L90LML23IL10I, T12P, K14KR, L19V, K20R, M36MI, R41K, L63P, A71T, V77I, I93LB
 06883A06883AGU581794PINAM46L, I54V, L76V, V82FL23I, L33FL10I, I13V, E35D, N37S, I62V, L63P, I64V, A71T, T74S, V77I, I93LB
 07763A07763AGU581867PINAM46L, I54V, V82A, L90ML10FI, L23IR57K, I62IV, L63P, I64IV, H69HY, A71V, I72IV, I93LB
 10962A10962AGU582026PINAM46MI, N88SL23IL10I, I13V, L63P, I64IM, V77I, I93LB
Knops (2010)ID0237ID0237-GT2GU271155Unknown, LPV>72M46L, L76V, V82F, L90ML23I, L33F, Q58EL10I, I13V, M36L, K55KR, I62V, I64VB
Margot (2010)2828HM116829PINAM46I, I54V, L76V, V82A, I84V, L90ML23I, L33F, Q58EL10I, I13V, K55R, R57K, D60E, I62V, L63P, A71I, I72V, V77I, I85V, L89M, I93LB
Rhee (2010)CA1834CA59294GQ211180RTV, NFV, IDV, APV, LPV, ATV446I54V, L76V, V82AL10F, L23I, L33F, Q58EI13V, R57K, D60E, L63P, A71V, I93LB
 CA14383CA63831 RTV, IDV, SQV, ATV518M46I, I54IV, I84V, L90ML23I, G73SL10LI, I13L, N37D, L63P, I66IV, C67CF, A71V, I72V, V77I, I93LB
 CA17599CA64053GQ211895RTV, IDV, LPV, APV, Unknown>415M46L, I54V, L76V, V82AL23I, F53LL10I, I15V, I62V, L63V, H69R, A71V, I72K, L89M, I93LB
Jones (2012)131910131910JN669506PINAL90ML23I, G73CL10I, N37D, R41RK, I62V, L63P, C67Y, Q92KB
 176684176684JN670408PINAM46L, I54V, V82A, L90ML23I, F53L, Q58QEL10V, N37D, K55R, D60E, L63P, A71V, V77VI, I85V, I93LB
 192523192523JN670855PINAM46L, I54V, V82AL23I, L24I, L33F, F53L, Q58EL10I, K20R, M36I, N37S, I62V, L63P, A71VB
Mollan (2012)MK85MK85w163 RTV, ATV163M46I, I47V, I54V, L76V, V82AL23I, Q58EL10V, R41K, K55R, D60E, I62V, L63P, A71V, V77I, I93LB
Diaz (2015)RenG16499RenG16499KT747527PINAM46I, L90ML23I, F53L, G73SL10I, I13V, I15V, K20T, E35G, M36I, P39S, I62V, L63P, A71V, I72L, T74S, V77I, I85VB
 RenG16241RenG16241KT747269PINAI50LL23I, F53LL10I, T12R, L19V, K20T, E34N, E35D, N37D, D60E, L63A, I64V, A71V, I72V, V77I, I85VB
 RenG16872RenG16872KT747900PINAM46I, I50V, V82A, L90ML23IL10R, T12P, L19Q, K20L, E34Q, N37D, L38L_DL, D60E, I62V, L63P, A71V, I72V, V77I, N83S, I93LB
 RenG16169RenG16169KT747197PINAM46L, I50L, V82AL23I, L33F, Q58EL10V, T12P, I15V, L19Q, K20M, L63P, A71TB
 RenG16546RenG16546KT747574PINAM46I, I50V, V82AL10F, L23I, L33F, F53L, Q58EI13V, Q61N, L63P, A71V, I93LB
 RenG17454RenG17454KT748482PINAM46L, I54V, L76V, V82AL23I, L24I, L33FL10I, I13V, K45KR, Q61N, L63A, C67E, H69K, A71V, V77IB
 RenG15919RenG15919KT746947PINAD30N, I54VL23I, L33LI, N88DL10I, I13V, I15V, K20RT, E35D, M36I, R41K, I62V, L63P, A71T, I72V, L89TB
 RenG15770RenG15770KT746798PINAD30NL23I, L33I, F53L, N88DL10R, I13V, K20R, E35D, M36L, N37T, R57K, Q61E, L63P, I64V, H69K, A71V, T74S, V77IB
 RenG17001RenG17001KT748029PINAI54L, L90ML23I, Q58E, G73SL10I, I62V, L63P, A71V, I72L, V77I, I93LB
 RenG16281RenG16281KT747309PINAV32I, M46I, I47V, I54V, V82A, L90ML23I, K43T, F53L, G73STL10I, T12N, I15IV, L19I, R41K, K55R, L63P, A71V, V77I, I93LB
 RenG17244RenG17244KT748272PINAD30N, I54LL23I, Q58E, N88DL10I, I13V, I15V, K20T, E35D, M36I, L63P, A71T, T74S, V77I, I93LB
 RenG15869RenG15869KT746897PINAI54V, V82A, L90ML23I, L33F, K43T, G73SL10I, T12E, I13V, L19I, K20KR, E35D, M36L, N37T, I62V, L63P, H69K, A71I, I93LB
 RenG15712RenG15712KT746740PINAD30N, M46I, I84V, L90ML23I, N88DI13V, G17D, K20R, N37S, L63P, K70R, A71V, I72V, V77I, I93L, T96TAB
 RenG16727RenG16727KT747755PINAM46L, I50V, I54V, V82AL23I, K43TT12K, I15V, L19I, K20T, E35D, M36I, L63P, A71V, I85IVB
 RenG16854RenG16854KT747882PINAD30N, M46I, L90ML23I, L33I, K43T, F53L, N88DL10I, T12I, G16E, K20KT, E35G, M36L, N37E, I62V, L63R, A71T, I85VB
 RenG16575RenG16575KT747603PINAM46I, L90ML23I, G73TL10V, K20R, E35D, M36V, N37S, L63P, H69Q, A71V, V77I, I93LB
 RenG15642RenG15642KT746670PINAM46I, I50V, I54IV, V82AL10F, L23I, L33F, K43T, F53FLK20T, E35D, M36I, N37T, R41K, K55KR, R57RK, I62V, L63P, I64L, H69Y, A71V, I72E, V77I, I93LB
 RenG16755RenG16755KT747783PINAM46L, I54V, V82AL10F, L23I, L24I, L33F, K43T, F53LI13V, L19I, K20R, E35D, M36I, R41K, K55R, R57K, D60E, Q61E, I62V, L63A, I72VB
 RenG15978RenG15978KT747006PINAM46I, I50LL23IT12N, L33LV, G51A, L63P, A71IV, I85IVB
 RenG16002RenG16002KT747030PINAM46I, L90ML23I, G73TL10I, I15V, K20T, E35D, M36I, P39PQ, R41K, K45R, Q61E, I62V, L63P, I72T, I93LB
 RenG16632RenG16632KT747660PINAD30N, L90LML23I, L33F, F53L, N88DI13V, K14KR, I15V, K20V, E35G, R41K, D60E, L63P, A71I, T74S, V77I, L89I, I93LB
 RenG16675RenG16675KT747703PINAM46I, I50L, L90ML23I, Q58EL10I, G16E, K20R, E34Q, E35D, M36V, P39S, W42Y, K55KR, D60E, I62V, L63P, I64V, A71AT, V77I, L89M, I93LB
 RenG15183RenG15183KT746211PINAM46L, I54V, V82A, I84VL23I, Q58QEL10V, I15V, L19I, K20R, E35D, M36I, D60E, I62IV, L63PB
 RenG13926RenG13926KT744954PINAI54V, V82A, L90ML23I, L33F, F53L, G73AL10I, I13V, K14R, I15V, K20T, E34Q, E35D, M36V, N37S, P39S, R41K, K55R, I62V, L63P, I64V, K70E, A71V, T74S, V77I, I93LB
 RenG14370RenG14370KT745398PINAI50L, L90LML23IL10V, G17E, K20R, E35D, M36I, N37S, R41K, L63P, A71V, V77I, I93LB
 RenG14039RenG14039KT745067PINAM46L, I54V, V82AL23I, L24I, L33FL10I, I13V, I15V, G16E, L19I, M36L, N37T, P39S, R41K, G51A, K55KR, I62V, L63T, I72T, T74A, L89MB
 RenG13596RenG13596KT744624PINAV32I, M46L, I47V, I50V, I54V, V82AL23IL10I, I15V, K20R, E35D, M36I, N37E, K55R, L63P, I64M, A71V, L89M, Q92KB
 RenG14097RenG14097KT745125PINAM46MI, I50LL23I, L33F, F53L, Q58E, G73SL10V, T12K, I13V, I15V, K20R, E35D, M36I, N37E, K55KR, L63P, A71ATB
 RenG15343RenG15343KT746371PINAI54V, I84V, L90ML23I, G73TL10I, I15V, L19I, K20R, E35D, M36I, L63P, A71V, I85V, I93LB
 RenG14730RenG14730KT745758PINAV32I, M46I, I47V, I54M, V82A, L90ML23I, L33FL10I, K20R, E35D, M36I, N37ND, K55N, R57RK, L63P, H69K, A71V, I72VB
 RenG13803RenG13803KT744831PINAM46L, I54V, V82T, L90ML23I, F53L, Q58QEL10I, I15V, K20R, E35D, M36I, N37E, K55R, L63P, A71T, I72IV, I85V, Q92K, I93L, C95FB
 RenG13899RenG13899KT744927PINAM46I, L76V, V82F, L90MV11I, L23I, L33FL10I, T12P, I13V, K14R, R57K, I62V, L63P, A71V, I72T, V77I, I93LB
 RenG14830RenG14830KT745858PINAM46I, I54V, L76V, V82F, L90ML23I, Q58EL10I, R41K, R57K, D60T, I62V, L63P, I64V, A71V, V77I, I93LB
 RenG13637RenG13637KT744665PINAI50LL23I, L33F, Q58E, G73GSL10V, I13V, I15V, G16E, E35D, M36V, P39PS, R41K, G51GA, I64IV, A71V, I72R, V75IB
 RenG14128RenG14128KT745156PINAD30N, I54L, L90ML10F, L23I, L33I, N88DI15V, K20T, E21K, E35D, M36I, L63P, H69Q, K70KE, A71I, I72IV, T74S, V77VI, I93LB
 RenG15460RenG15460KT746488PINAM46I, L90ML23I, F53L, G73SW6L, Q7E, I13V, I15V, K20V, E34Q, E35D, M36V, P39S, D60E, I62V, L63P, A71V, V77I, I93L, N98IB
 RenG14333RenG14333KT745361PINAD30N, I54LL23I, N88DL10LGRV, I15V, K43R, R57K, L63P, H69Q, K70R, A71I, V75I, V77I, I85V, Q92K, I93LB
 RenG12601RenG12601KT743629PINAM46L, I50L, V82AL23I, L33F, K43KTL10LR, T12P, L19I, K20RT, E35D, M36V, N37H, R41K, K45KR, R57K, L63P, I64IL, V77I, I93LB
 RenG13454RenG13454KT744482PINAI54LL23I, G73CL10I, E34ED, E35D, M36I, D60E, Q61E, I62V, L63P, I72T, I93LB
 RenG13521RenG13521KT744549PINAI50L, V82AL23I, L33F, Q58E, G73SL10V, N37H, R41K, L63P, A71V, I72V, V77I, I93LB
 RenG13042RenG13042KT744070PINAD30N, M46ML, I54LL23I, L33I, K43KT, G73GS, N88DI13V, K20R, D25DG, E34D, E35D, M36I, K55N, L63P, A71T, T74TS, V75I, G86GR, I93LB
 RenG12413RenG12413KT743441PINAM46I, L90ML23I, F53L, G73TL10V, G17GE, N37P, K43KQ, K55R, R57K, D60E, Q61N, L63P, A71I, V77I, I93LB
 RenG12298RenG12298KT743326PINAM46L, I54V, V82A, L90ML23I, L33F, Q58EQ7K, L10I, L19I, R41K, K55KR, I62IV, L63P, A71T, I72K, V77I, I93L, N98IB
 RenG12647RenG12647KT743675PINAV32I, M46I, I47V, I54M, I84V, L90MV11VI, L23I, G73S, L89VL10I, I13V, I15V, L33F_E, N37S, L63P, A71V, I72M, V77IB
 RenG12491RenG12491KT743519PINAM46I, I54ILM, N88S, L90ML23I, Q58EL10I, I13V, D60DN, I62IV, L63P, A71I, V77I, I93LB
 RenG13414RenG13414KT744442PINA L23I, V32A, L33F, K43T, G73SI13V, I15V, E34D, M36L, L63P, H69Y, A71V, L89TB
 RenG12643RenG12643KT743671PINAM46I, L90ML23I, G73CT12K, I13V, L19I, R41K, K43R, I62V, L63P, I64IV, H69Q, T74S, V77IB
 RenG13086RenG13086KT744114PINAI54L, N88SL23I, Q58EL10V, T31A, I62V, L63P, H69K, A71I, V77I, I93LB
 RenG12470RenG12470KT743498PINAI54V, V82F, L90LML10F, L23I, L33I, K43T, N88DL19LR, E34ED, E35D, M36I, R41K, I62V, L63P, A71I, L89F, I93LB
 RenG11800RenG11800KT742828PINAM46L, I54V, V82A, L90ML10FI, V11VI, L23I, Q58E, G73S, L89VI13V, I15V, K20I, L33V, M36I, G51A, I62V, L63P, A71VB
 RenG13199RenG13199KT744227PINA L23I, F53L, G73STL63P, A71V, V77I, I93LB
 RenG10712RenG10712KT741740PINAM46I, I50L, V82A, L90ML23I, L33F, G73SL10I, I13V, K55R, R57K, D60E, L63P, A71I, I72V, V77VI, T91S, I93LB
 RenG11163RenG11163KT742191PINAL90ML23I, Q58E, G73TL10LI, I13A, K14R, K20I, E35N, M36I, N37S, I62V, L63P, I64V, A71V, I93LB
 RenG10560RenG10560KT741588PINAM46I, I50V, I54V, V82C, L90ML10F, L23I, L33I, K43T, N88D, L89VI13V, K14R, E35D, M36I, I62V, L63P, A71IB
 RenG11257RenG11257KT742285PINA L23IL10I, T12TA, I13V, K14KR, R41K, L63P, K70R, A71V, I72L, V77I, I93LB
 RenG11049RenG11049KT742077PINAV32I, M46I, I54M, V82C, I84V, L90MV11I, L23I, L33F, F53L, Q58E, T74P, L89VL10I, T12N, I13V, I15V, K20R, E34Q, E35D, M36L, R41K, D60E, I62V, L63P, I64V, G73V, V77IB
 RenG11524RenG11524KT742552PINAL90ML23I, F53LI13V, G17E, K20T, E35D, M36I, N37D, D60E, I62V, L63P, K70KR, A71I, V77VI, L89I, I93LB
 RenG11376RenG11376KT742404PINAM46I, I50V, I54V, V82AL10F, L23I, L33LFR41K, L63P, H69HR, A71TB
 RenG11714RenG11714KT742742PINAI84VV11I, L23I, Q58QE, G73STL10I, T12D, I15IV, K20R, E35D, M36I, D60E, I62V, L63P, A71I, I72L, T91S, I93LB
 RenG11652RenG11652KT742680PINAM46L, L90ML23I, Q58EL10I, N37S, K55KR, Q61QE, I62V, L63P, I64V, V77VI, I93LB
 RenG11466RenG11466KT742494PINAM46L, I50V, V82AL10F, L23I, L33F, Q58EK20R, E35D, M36I, R41K, R57K, L63E, I64V, H69YB
 RenG11374RenG11374KT742402PINAV32I, M46I, I47V, I54L, V82TL10F, L23I, L33F, K43TG17E, L19I, K20R, E35D, M36I, L63T, H69HY, A71V, I72T, T74S, N83NY, I93LB
 RenG10439RenG10439KT741467PINAM46IL23IL10I, L33V, N37A, L63P, H69K, I85V, L89T, I93LB
 RenG10820RenG10820KT741848PINAL90ML23I, L33F, F53L, G73SI13V, K20R, L63P, C67F, A71V, V77I, I93LB
 RenG10481RenG10481KT741509PINAM46L, I54V, V82AL23I, K43TL10I, I15V, G16GE, L19I, K20T, I62IV, L63V, I64VB
 RenG11578RenG11578KT742606PINAM46I, I54V, L76V, V82TL10F, L23II15V, K20R, M36I, R57RK, I62V, L63P, I64V, A71V, I93LB
 RenG11108RenG11108KT742136PINAM46I, V82T, I84VL10F, L23II15V, L19LI, K20R, M36I, N37D, K43KQ, K55R, R57K, L63P, A71T, I93LB
 RenG10335RenG10335KT741363PINAM46L, I50LL23I, L33F, G73ST12P, I13V, K14R, I15V, K20T, E35Q, M36I, N37E, K55KR, L63P, A71I, I72VB
 RenG10760RenG10760KT741788PINAI54V, L90ML23I, G73STL10I, I15V, K20V, E35G, M36I, I62V, L63P, A71IV, T74S, V77I, I85IV, I93LB
 RenG10459RenG10459KT741487PINAM46I, I50V, V82A, L90ML23I, L33F, K43T, F53LL10I, K20R, E34R, E35D, M36IV, R41K, R57K, D60E, Q61D, L63P, I64IM, I66IV, A71T, I72IV, V77I, I93LB
 RenG10051RenG10051KT741079PINAL90ML23I, F53L, G73SL10LI, K14KN, I15V, K20T, E34EQ, E35D, M36I, R41K, K45R, I62IV, L63P, I66IV, A71IL, I72T, V77I, I93LB
 RenG11425RenG11425KT742453PINAM46L, I54V, V82A, L90ML23I, F53FL, G73GSL10V, I15V, K55R, R57K, D60E, Q61D, L63P, A71V, I72V, I93LB
Lopez (2016)2013-1602013-160KT386100PINAL90ML23I, F53LG16E, Q18QH, K20T, E35D, M36I, L63Q, I64V, A71V, T74S, V77I, I93LB
 2012-0372012-037KT385946PINAI54V, L76V, V82F, L90ML23I, L33FK20R, E35D, M36I, N37E, R41K, R57K, D60E, I62V, L63P, K70R, P79A, R87RT, L89IB