<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype B
Gene PR
Mutation K20V
Rx >= 1 PI
IncludeMixtures No
References 16
Patients 100
Isolates 109
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Baxter (2000)GART-G20GART-20 PI, NFVNAM46I, L90M K14R, K20V, N37E, A71VB
 GART-G136GART-136 PI, NFVNAD30N, M46MLN88DK20V, A71VB
Shulman (2000)CA1466CA11103AY798399NFV, IDV, RTV101M46I, L90MG73CK20V, N37S, R41K, I62IV, L63P, I64V, T74S, V77IB
Gonzales (2001)CA4113CA9819AY031103IDV, NFV166M46I, V82T, I84V, L90ML10FI3IT, I15V, L19I, K20V, M36I, I62V, L63A, A71V, I85V, I93LB
 CA4510CA11092AY031349NFV, SQV, RTV, APV85M46I, V82T, I84VV11IL10I, I13V, K20V, M36I, L63P, A71T, I72VB
 CA4874CA12063AY031514IDV171M46I, L76V, V82A L10I, I13V, L19T, K20V, N37D, K55KR, I62V, L63P, A71T, T74SB
 CA5990CA14913AY032236SQV, NFV216L90M K20V, E35D, M36I, I62V, L63P, I64V, T74SB
 CA6470CA16250AY032421RTV, IDV211I54V, V82AL89LVL10I, I13V, K20V, M46X, L63P, A71T, I93ILB
 CA6585CA16507AY032491IDV, SQV, RTV, NFV64M46I, L90MG73SL10V, T12D, I15V, K20V, D60E, Q61D, I62V, L63P, C67Y, H69K, A71V, I72L, V77IB
Kantor (2002)CA1466CA13957AY047430NFV, IDV, RTV128M46I, L90MG73CK20V, N37S, R41K, I62V, L63P, I64V, T74S, V77I, I93ILB
Margot (2002)MM-4011368054011368051 PINAD30NN88DT12D, L19I, K20V, I62V, L63P, A71T, T74S, V77I, I85VB
Tural (2002)347965347965 SQV, IDV157L90MG73SK20V, E35D, M36I, D60E, I62V, L63P, H69K, A71VB
Monno (2003)ML_Pat97ML_Pat97 PINAM46I, I84V, L90MG73SL10I, I13V, Q18H, K20V, A22V, L63P, A71V, I72L, I85VB
Saah (2003)AS-32AS-32 NFV102L90MQ58E, G73SI13V, K20V, L63P, A71V, V77IB
Gomez-Carrillo (2004)106543106543AY365752PINAM46I, N88S, L90M T4P, L10I, K14R, I15V, K20V, M36I, I62V, L63P, G73D, Q92K, I93LB
 114241114241AY365893PINAM46I, I47V, I54V, I84V, L90MV11VI, G73SL10Y, I15V, G17D, Q18QH, K20V, E35D, M36I, N37E, K55R, D60E, I62V, L63P, C67F, A71V, I72T, I85V, I93LB
Rhee (2004)CA14192CA33304AY798495IDV, NFV, SQV, RTV285L90MG73SL10I, K14R, K20V, L63P, A71IV, V77I, I93LB
Garcia-Bujalance (2005)GBS_22GBS_22AY872303SQV, NFV M46I, L90M K20V, L63P, A71I, T74S, V77I, I93LB
Rhee (2005)CA799CA21348AY796485RTV, IDV, SQV, NFV, Unknown, LPV, APV>210I54V, V82A, L90ML33F, G73S, L89LVL10I, I15V, K20V, L24F, E35DN, M36I, R57K, I62V, L63P, A71V, I72MB
 CA1274CA39309AY796583SQV, IDV, RTV, NFV279L90MQ58E, G73GSL10I, I15V, L19LP, K20V, M36I, I62V, L63PB
 CA1420CA20635AY796661SQV, RTV, IDV, NFV, APV252I54V, I84V, L90ML33F, G73SL10I, K20V, E35D, M36L, N37D, I62V, L63P, C67F, A71VB
 CA1466CA37901AY796710NFV, IDV, RTV, Unknown>241M46I, L90MG73CK20V, N37S, R41K, I62V, L63P, I64V, T74S, V77I, I93ILB
  CA42649AY796711NFV, IDV, RTV, Unknown>241M46I, L90MG73CK20V, N37S, R41K, I62V, L63P, I64V, T74S, V77I, I93LB
 ASRU016ASRU016 IDV, SQV, NFV67L90MG73SI15V, K20V, E35D, N37S, R41K, I62V, L63P, A71XB
 CA5990CA38036AY797375SQV, NFV, RTV, APV395M46I, I50V, L90ML10F, G73A, L89LVI13V, K20V, M36I, I62V, L63P, I64V, T74SB
 CA6470CA33557AY797411RTV, IDV, APV313I47IV, I54V, V82AK43T, L89VL10I, I13V, K20V, M46X, L63P, A71TB
 CA7938CA20399AY797603NFV172L90M I15V, K20V, E35ED, M36I, I62V, L63P, A71T, I72XB
  CA41246AY797604NFV187L90M I15V, K20V, M36I, I62V, L63P, A71T, I72ITB
 CA14170CA33276AY797993NFV, IDV, Unknown>58M46I, L90M L10LI, I13V, K14KR, K20V, R41K, K55R, R57K, L63P, I93LB
 CA14192CA42733AY798000IDV, NFV, SQV, RTV, APV, LPV396I84V, L90MV11I, G73S, L89VL10I, K14R, K20V, L63P, A71I, P79A, I93LB
Baxter (2006)12-12811281-30424DQ875986PINAM46I, L90MG73SL10I, K20V, L24LM, D25N, D60E, Q61E, I62IV, L63P, H69Q, A71V, I72R, V77IMB
 12-22362236-30725DQ876047PINAM46I, I54V, I84VQ58E, L89VL10I, I13V, K20V, P39S, R41K, K55R, L63P, H69Q, A71T, Q92KB
 12-40684068-30221DQ876120PINAM46L, I54V, I84V, L90MV11I, G73GSL10I, I15V, K20V, M36I, K55KR, D60E, I62V, L63P, A71T, I72T, I85VB
 12-40504050-30820DQ876156PINAI54V, I84V, L90ML10F, G73SI15V, L19P, K20V, L24F, E34Q, M36I, N37D, I62V, L63P, A71V, I72L, P79D, I93LB
 12-40164016-30723DQ876185PINAM46L, I54V, I84V, L90MV11I, G73SL10I, I15V, L19P, K20V, A22V, M36MI, K55KR, D60E, I62V, L63P, A71T, I72T, I85V, Q92QKB
 12-14791479-30731DQ876190PINAI54V, V82A, L90ML10F, K43T, L89LVV11L, T12K, I15V, Q18H, L19I, K20V, E21ED, E35D, M36I, N37D, R57K, I62V, L63P, A71I, I85V, Q92K, I93LB
 12-16471647-30421DQ876200PINAV32I, M46I, I47V, I54M, I84V, L90MV11I, L33I, L89VL10I, I13V, G16A, L19P, K20V, A22V, E35G, N37D, D60E, L63P, K70T, A71I, G73E, V77I, I93LB
 12-23992399-30818DQ876221PINAV32I, M46I, I47V, I54L, I84V, L90ML10FYI15V, G16A, K20V, E34Q, L63Q, I64V, H69Q, T74S, V77I, I85V, L89I, T91S, Q92KB
 12-17051705-30409DQ876291PINAM46I, I54M, I84V, L90ML10F, L33F, G73S, L89VI13V, I15V, L19I, K20V, E35N, M36I, N37T, R41K, I62V, L63P, I66F, A71V, P79AB
 12-10411041-30717DQ876304PINAM46L, I54V, V82A, I84VV11I, L24IL10I, I15V, L19P, K20V, A22V, K55KR, I62IV, L63P, A71V, I72V, T74S, T91SB
 12-17831783-30515DQ876313PINAM46I, I54V, L76V, I84V, L90ML10F, V11I, Q58E, G73S, L89VI15V, K20V, E35D, M36I, N37E, R57RK, I62V, L63P, K70R, A71V, I72L, I85VB
 12-13271327-30708DQ876332PINAI54V, I84V, L90ML10F, G73TI13M, K14KR, I15V, K20V, E35D, M36I, I62V, L63P, I64V, E65D, I66IV, A71I, I72IM, I85IV, I93LB
 12-22812281-30822DQ876337PINAM46I, I54V, L76V, I84V, L90ML10F, V11I, G73S, L89VI13V, I15V, K20V, E34Q, M36I, R57K, I62V, L63P, A71V, I72L, P79ADB
 12-20272027-30722DQ876338PINAV32I, M46I, I54V, V82A, L90MV11I, K43T, F53L, L89VL10V, I13V, K20V, M36I, Q61H, L63P, A71I, Q92KB
 12-21662166-30820DQ876353PINAM46I, I47V, I54A, V82A, L90MG73TL10I, T12TS, K14R, I15V, K20V, E34Q, E35D, M36I, N37NS, R41K, K55KR, D60E, I62V, L63P, I64V, A71V, I85VB
 12-20332033-30618DQ876355PINAI54V, I84V, L90ML10F, G73SI13M, I15V, K20V, M36I, I62V, L63P, I66V, A71V, N83SB
 12-22672267-30820DQ876363PINAV32I, M46I, I47V, I54M, L90MF53L, G73A, L89VL10I, I13V, L19P, K20V, A22AV, E35G, M36I, D60E, I62V, L63P, I64V, A71I, I72T, V77I, V82I, I85VB
 12-10821082-30328DQ876422PINAI54V, V82T, I84V, L90MG73S, L89VL10I, V11L, I13V, Q18H, K20V, M36I, N37D, L63P, A71VB
 12-12801280-30417DQ876479PINAM46I, I54V, I84V, L90ML10F, V11VI, L24LIM, Q58E, G73SI15V, L19LP, K20V, A22V, D60N, I62IV, L63P, H69HQ, A71V, I72L, V77I, N83NS, I85VB
 12-22722272-30804DQ876581PINAV32I, M46I, I47V, L90ML10F, L33F, Q58E, G73S, L89VV11VL, K14KR, I15V, L19I, K20V, M36I, D60E, I62V, L63P, H69KQ, V77I, I85VB
 12-21612161-30708DQ876586PINAM46I, I54V, V82CG, I84IV, L90MF53FL, Q58QEL10I, V11L, I13V, K20V, K55KR, I62V, L63P, A71V, Q92QKRB
 12-20992099-30613DQ876602PINAV32I, M46I, I47V, I54M, I84V, L90MV11IL, G73S, L89VL10Y, I13V, K20V, L38W, I62V, L63P, A71IVB
 12-15041504-30626DQ876626PINAV32I, M46I, I47V, I54L, I84V, L90ML10F, V11I, Q58E, G73S, L89VI15V, G16A, K20V, F53Y, L63P, T74K, V77I, I85VB
 12-20132013-30616DQ876681PINAL90LM L10I, I13AV, K20V, M36I, L63P, A71ATB
 12-15891589-30617DQ876687PINAI47V, I54L, V82A, L90ML10F, V32I_R, G73GS, L89LVI15V, G16E, K20V, L63H, K70E, A71V, V77ILB
 12-15981598-30711DQ876702PINAV32I, M46I, I54V, L90ML10F, K43T, F53LV11L, K20V, E35D, M36I, N37K, L63P, A71LB
 12-31193119-40623DQ879132PI, RTV, TPV>62M46L, I54V, V82T, L90MV11I, L33I, N88DI15V, K20V, E35G, M36I, R41K, I62V, L63P, I66L, A71T, I72M, I85V, F99YB
 12-31573157-30515DQ876726PINAM46IL, I54V, I84V, L90MG73S, L89VL10I, V11L, K14KR, I15V, K20V, M36MI, R41RK, D60E, I62V, L63P, A71V, I72L, P79A, I85VB
 12-19121912-30514DQ876760PINAI54V, I84V, L90ML10F, V11I, L33LF, G73S, L89VI15V, K20V, E35D, M36I, R57K, L63P, A71V, I72FL, P79A, I85VB
 12-19131913-30515DQ876762PINAD30N, I54LV, V82A, L90ML10F, L33F, N88DI15V, K20V, E35N, M36I, R41K, I62V, L63P, K70N, A71V, I72VB
 12-14691469-30422DQ876874PINAI54IV, V82A, L90MV11IL, L33F, F53LL10I, I15V, K20V, L24F, E35N, M36I, R41K, K45KR, K55KR, D60E, I62V, L63P, A71I, I85IV, L89LIMB
 12-14971497-30620DQ876892PINAI54V, V82F, L90MF53LL10I, V11L, I13V, I15V, K20V, E35D, M36I, N37ND, R41K, D60E, I62V, L63P, I64V, A71VB
 12-19601960-30714DQ876992PINAM46I, L90MQ58EL10V, I13V, K14R, I15V, Q18E, K20V, I62V, L63P, A71V, V77I, Q92KB
 12-30833083-30613DQ877156PINAM46I, I54V, I84VL24I, G73TL10Y, I13V, I15V, Q18QH, K20V, F53Y, Q61QH, L63P, V77VIB
  3083-40114DQ879131PI, RTV, TPV>31M46I, I54V, I84VL33F, G73TL10Y, I13V, I15V, K20V, E21D, L24M, F53Y, L63P, V77IB
 12-30923092-30506DQ877192PINAM46I, I47V, I54V, I84V, L90ML10F, V11VI, G73TI15V, K20V, M36I, R41K, I62IV, L63P, A71V, I85V, I93LB
 12-30963096-30513DQ877196PINAI54V, V82C, L90ML10F, G73SI13M, I15V, G17E, K20V, L24F, M36I, N37D, K43KR, R57K, D60E, I62V, L63P, A71V, I72RB
 48-10751075-30626DQ877261PINAI54V, V82A, L90ML33F, F53L, T74PSL10I, I13V, I15IV, G16A, K20V, E35D, M36I, R41K, K55KR, R57K, Q61N, L63AV, A71V, I93LB
 48-12091209-30701DQ877751PINAM46I, I54V, I84V, L90ML10F, V11I, L33F, G73TK20V, E35D, M36I, I62V, L63P, I64V, C67F, H69R, A71V, I72L, P79A, I85VB
 48-22452245-30722DQ877884PINAM46I, I50V, I54V, V82A, L90ML33FL10I, I13V, K20V, E35D, M36V, N37C, L63P, I64V, A71V, V77I, I93L, C95CFB
 48-30043004-30226DQ877914PINAM46I, I54V, V82T, I84VL10F, L24I, G73SI15V, K20V, M36I, L63P, A71V, I85VB
 48-30933093-30401DQ878000PINAM46I, I54M, L90ML10F, L33F, Q58E, G73S, L89VK20V, E35N, M36I, R41K, K55R, D60E, Q61E, I62V, L63P, A71V, I72T, I85V, I93LB
 48-31663166-30424DQ878075PINAM46I, I54V, L76VL24I, Q58EL10V, I15V, K20V, E35N, M36I, K55KR, R57K, D60E, I62V, L63P, I64V, I72V, V82IB
 48-31763176-30425DQ878085PINAI47V, G48V, I54M, L76V, V82C, L90MF53L, G73A, L89VL10I, V11L, I13V, G16A, K20V, E34Q, N37D, L63P, H69Y, A71V, V77I, I93LB
 48-40144014-30408DQ878250PINAM46L, I84V, L90ML10F, V11I, G73C, L89VI13V, I15V, G16AE, K20V, I62V, L63T, I64V, C67F, T74E, V77VI, P79AB
 48-40244024-30630DQ878258PINAV32I, M46I, I47V, I54L, I84V, L90ML10F, V11I, L33F, L89VK14R, I15V, K20V, E35H, M36IL, R41K, L63P, C67CY, A71I, I85V, Q92KB
 48-40404040-30512DQ878274PINAI54M, I84V, L90ML10F, L33F, G73S, L89VI13V, G16E, K20V, M36L, R41RK, I62V, L63H, A71VB
 48-40594059-30318DQ878291PINAI54IV, I84V, L90MG73SL10I, T12S, I15V, L19T, K20V, M36MI, D60E, L63P, A71V, I72ITB
 48-42134213-30429DQ878446PINAI54L, V82A, L90ML10F, L33F, Q58E, L89VI13V, K20V, E35G, M36I, N37D, R57K, D60E, I62V, L63P, A71T, Q92KB
 48-60996099-30618DQ878694PINAM46L, I54L, V82A, L90ML33I, Q58E, G73SL10I, K20V, E35D, M36I, N37D, Q61D, I62V, L63P, I66F, C67Y, A71T, I72RB
 48-62246224-30730DQ878791PINAV32I, M46I, I47V, I54M, V82A, L90ML10F, V11VI, Q58E, G73S, L89VI13IV, I15IV, G16E, L19V, K20V, E35D, M36I, I62V, L63S, A71VB
 48-70647064-30729DQ878932PINAM46I, I50V, I54V, L90ML10F, L23I, G73S, L89VI15V, K20V, E35D, M36I, N37D, D60E, Q61H, L63P, A71V, I72M, I85V, Q92K, I93LB
 48-71567156-30930DQ878994PINAI54V, V82AL24I, L33F, F53LL10I, T12P, K14R, K20V, E35D, M36I, N37D, D60E, I62V, L63P, A71IB
 48-92869286-30929DQ877301PINAM46I, L76V, I84VL10F, L33FI15V, G16E, K20V, M36L, N37NI, P39S, K55KR, I62V, T74S, I85V, L89I, T91AB
 48-92819281-30925DQ877617PINAM46I, I54V, I84V, L90ML10F, V11I, G73ST12S, K14N, I15V, L19Q, K20V, M36I, K55R, R57K, I62V, L63P, A71V, I72L, N83S, I85VB
 48-91079107-30915DQ877695PINAM46I, I47IV, I54V, L76V, I84V, L90MV11I, G73GDNS, L89VL10I, I13V, I15V, K20V, M36MI, R57K, I62V, L63P, A71IV, T74S, T91TS, Q92KB
 48-90429042-30924DQ877735PINAI54L, V82A, L90ML33F, G73CL10I, T12N, I13V, G16E, K20V, E34EQ, K55R, R57K, Q61D, I72R, V77IB
Dau (2010)06135A06135AGU581708PINAM46I, I54V, I84V, L90ML10F, G73TK20V, N37S, K55R, R57K, L63P, C67F, A71V, I72L, V77I, I85V, I93LB
 06271A06271AGU581729PINAM46L, I54V, V82A, L90ML10F, V11I, Q58E, G73SI15V, K20V, M36I, R41K, I62V, L63P, A71V, I72LB
 06333A06333AGU581733PINAV32I, I47A, L90MV11I, L89VL10I, I13V, K20V, M36I, I62V, L63P, A71IB
 06400A06400AGU581741PINAM46I, I47V, I54V, I84V, L90MG73CL10I, I13V, K20V, N37D, D60E, Q61E, I62V, L63P, C67F, A71T, I72T, P79D, T91S, I93LB
 06461A06461AGU581749PINAM46MI, I47IV, I54V, I84V, L90ML10F, Q58QE, G73ST12K, K14M, I15V, L19P, K20V, M36I, R57K, I62V, L63P, A71V, I72IL, N83S, I85VB
 06500A06500AGU581756PINAM46I, I54V, L76LV, V82VFI, L90ML33I, G73C, L89VL10I, V11L, I13V, K20V, M36I, P39T, I62V, L63P, I64V, T74S, I93ILB
 06691A06691AGU581766PINAM46I, I54V, I84V, L90ML10F, G73SK14R, I15V, Q18H, K20V, E34Q, E35D, M36I, N37D, I62V, L63P, A71I, I72K, P79A, I85V, I93LB
 07106A07106AGU581818PINAM46I, I47V, I54V, V82A, L90ML33I, K43T, F53L, L89VL10I, I13V, L19V, K20V, E35D, M36I, I62IV, L63P, A71TB
 07893A07893AGU581880PINAI54M, L76V, I84V, L90ML33I, G73S, L89VL10I, V11L, I13V, Q18H, K20V, M36IL, I62V, L63P, A71IVB
 08848A08848AGU581950PINAM46I, V82VA, L90MG73SL10I, I15V, K20V, K45KR, R57K, L63P, A71I, I72R, V77I, I93LB
 10153A10153AGU581994PINAV32I, M46I, I47V, I54M, I84VL10F, L89VI13V, L19LP, K20V, M36I, L63P, A71V, T74SB
Rhee (2010)CA14192CA126200GQ213916IDV, NFV, SQV, RTV, APV, LPV605I84V, L90MV11I, G73S, L89VL10I, I13IV, K14R, K20V, L63P, A71I, P79A, I93LB
 CA25602CA79443GQ212821Unknown, RTV, ATV>107L90MF53L, G73SK20V, L63P, A71V, V77I, I85IVB
 CA38129CA84909GQ213273PI, Unknown, DRV, RTV>23V32I, M46I, I47V, I54M, I84IV, L90MV11I, L33LF, Q58E, G73S, L89VL10I, T12K, I13V, K20V, E35G, M36I, N37ND, R57K, L63P, I64V, A71IVB
Jones (2012)129273129273JN669462PINAM46I, I54V, I84V, L90ML10F, G73TI13V, I15V, Q18H, K20V, L24F, L33LM, M36L, N37P, Q61H, I62V, L63P, I66V, A71T, I72T, V77I, I93LB
 152142152142JN669774PINAM46I, I47V, I54V, I84V, L90MV11I, L33I, G73S, L89VL10Y, I13V, I15V, G17D, Q18H, K20V, E35N, M36I, N37E, K55R, R57RK, D60E, I62V, L63P, A71V, I72T, I85V, R87RG, I93LB
 152995152995JN669792PINAM46I, I54L, L90M L10R, I13V, K20V, E35N, M36I, K55R, D60E, I62V, L63P, I64VB
 154694154694JN669823PINAM46L, I50V, I54V, L90MQ58EL10I, I13M, I15V, L19I, K20V, D25DN, E35DN, M36I, N37D, D60DN, L63P, I66V, A71V, I72VB
 157470157470JN669886PINAM46I, I47V, I54V, I84V, L90MV11I, L33I, G73S, L89VL10Y, I13V, I15V, G17D, Q18H, K20V, E35N, M36I, N37E, K55R, R57K, D60E, I62V, L63P, A71V, I72T, I85V, I93LB
 159242159242JN669945PINAM46L, L90ML10FI, L33F, G73S, L89VI13V, K20V, E35G, M36I, N37D, R41K, I62V, L63P, I93LB
 202016202016JN671249PINAI54V, V82FQ58EL10I, I13V, K20V, E35D, M36I, N37DE, I62V, L63T, I64V, T74S, V77IB
 202025202025JN671250PINAM46I, I84V, L90ML10F, Q58QE, N88GI15V, Q18H, K20V, M36I, K55R, I62V, L63P, A71T, I72V, I85VB