<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype B
Gene PR
Mutation V11L
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 65
Isolates 70
 
Show mutation frequency as:
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Rhee (2005)CA622CA37880AY798413IDV, SQV, RTV, LPV387M46I, I54V, V82T, I84V, L90ML10F, L33F, G73S, L89VV11L, G16A, L19I, R41K, L63P, A71V, T91S, I93LB
 CA1341CA48551AY796641IDV, SQV, RTV, NFV, APV, LPV304M46L, I54V, V82A, L90ML33F, Q58E, G73AL10I, V11L, G16A, L19I, R41K, K55R, D60E, I62V, L63P, I64M, A71I, I72M, V77I, I93LB
 CA1590CA42641AY796792IDV, SQV, RTV, NFV, APV413M46I, I50V, I54V, V82L, L90ML33F, G73T, L89VL10I, V11L, T12E, I13V, L19IM, M36I, R41K, L63P, A71V, V77I, I93LB
 CA4497CA33389AY797111IDV, SQV, NFV, RTV, LPV, APV310I54V, V82T, I84VL89VL10I, V11L, I13V, I15V, K20I, E35D, M36I, N37D, D60E, L63P, K70E, A71I, Q92KB
  CA34161AY797112IDV, SQV, NFV, RTV, LPV, APV350I54V, V82T, I84VL89VL10I, V11L, I13V, I15V, K20I, E35D, M36I, N37D, D60E, L63P, K70E, A71I, Q92KB
  CA42653AY797113IDV, SQV, NFV, RTV, LPV, APV417I54V, V82T, I84VL89VL10I, V11L, I13V, I15V, K20I, E35D, M36I, N37D, D60E, L63P, K70E, A71I, Q92KB
Baxter (2006)12-10011001-30227DQ875949PINAG48GASW, I54T, V82AL33FL10I, V11L, G16A, L19V, K20R, E34Q, E35D, M36I, N37E, D60E, L63P, I64IL, A71V, V77I, L89I, I93LB
 12-13211321-30402DQ875968PINAI54M, I84V, L90ML10F, Q58E, G73S, L89VV11L, T12S, I13V, K14R, I15V, Q18H, L19Q, K20I, E34Q, M36MI, N37S, G51A, D60E, L63P, A71V, P79QB
 12-10931093-30224DQ875992PINAG48V, I50V, I54V, V82SL89VL10I, V11L, K14R, I15V, K20I, M36I, R41K, I62V, L63P, A71V, T74S, I85V, T91TSB
 12-40794079-30224DQ876172PINAM46I, I84V, L90ML33I, G73SL10I, V11L, I13V, K14R, A22V, E35D, M36I, N37D, I62V, L63P, A71V, I72VB
 12-14791479-30731DQ876190PINAI54V, V82A, L90ML10F, K43T, L89LVV11L, T12K, I15V, Q18H, L19I, K20V, E21ED, E35D, M36I, N37D, R57K, I62V, L63P, A71I, I85V, Q92K, I93LB
 12-10051005-30304DQ876196PINAM46I, I54L, V82T, I84V, L90ML33F, G73SL10I, V11L, I13V, E34Q, N37S, K55R, R57RK, L63P, A71V, I93LB
 12-16431643-30312DQ876198PINAM46I, I54V, L76V, I84V, L90ML33F, L89VL10I, V11L, I13V, G16A, N37D, K55R, D60E, L63P, H69Y, A71V, I72FL, V77VI, I93LB
 12-13221322-30423DQ876328PINAM46I, I54V, V82C, I84V, L90ML33F, G73S, L89VL10I, V11L, G16A, E34Q, K55R, R57K, L63P, H69Q, K70E, A71V, I72L, T91S, I93LB
 12-23762376-30821DQ876348PINAM46I, I50L, I54V, V82L, L90ML33F, G73C, T74PL10I, V11L, I13V, G16A, K20R, E35D, M36I, N37D, R41K, I62V, L63P, A71V, L89A, I93LB
 12-10751075-30314DQ876398PINAV32I, I47V, I54M, L90ML10F, Q58E, G73GS, L89VV11L, I13V, K20T, E35D, M36I, N37D, D60E, Q61E, L63P, A71I, V77VI, I93LB
 12-10821082-30328DQ876422PINAI54V, V82T, I84V, L90MG73S, L89VL10I, V11L, I13V, Q18H, K20V, M36I, N37D, L63P, A71VB
 12-13401340-30421DQ876444PINAV32I, M46I, I47V, I54M, L90ML33F, K43T, G73S, L89VL10V, V11L, I13V, K14M, Q18H, E34Q, N37S, Q61H, I62V, L63P, A71I, V77I, V82VI, I93L, G94DB
 12-22572257-30818DQ876574PINAI54L, I84V, L90ML33F, T74PL10I, V11L, I13V, K20R, E34Q, E35D, M36I, N37D, D60E, I62V, L63P, A71V, I93LB
 12-21612161-30708DQ876586PINAM46I, I54V, V82CG, I84IV, L90MF53FL, Q58QEL10I, V11L, I13V, K20V, K55KR, I62V, L63P, A71V, Q92QKRB
 12-22972297-30812DQ876657PINAM46I, I54AV, V82A, I84VL10F, L89VV11L, I13V, L19Q, K20I, M36I, L63P, H69K, K70R, A71T, T74S, T91SB
 12-15981598-30711DQ876702PINAV32I, M46I, I54V, L90ML10F, K43T, F53LV11L, K20V, E35D, M36I, N37K, L63P, A71LB
 12-12621262-30324DQ876710PINAV32I, M46I, I47V, I54L, V82C, L90MK43T, L89VL10I, V11L, I15V, L19LQ, K20I, E35D, M36I, N37ND, R41K, L63P, A71V, I85V, Q92KB
 12-31573157-30515DQ876726PINAM46IL, I54V, I84V, L90MG73S, L89VL10I, V11L, K14KR, I15V, K20V, M36MI, R41RK, D60E, I62V, L63P, A71V, I72L, P79A, I85VB
 12-14021402-30702DQ876770PINAV32I, M46I, I47V, I54M, L90MK43T, G73S, L89VL10I, V11L, I13V, L19I, K20R, E35D, M36I, N37H, L63P, A71I, I72E, V77I, V82I, I93LB
 12-14351435-30728DQ876834PINAI54M, I84V, L90ML33F, G73S, L89VV11L, I13V, R57K, D60E, I62V, L63P, I66F, A71V, I72M, V77I, R87SB
 12-14971497-30620DQ876892PINAI54V, V82F, L90MF53LL10I, V11L, I13V, I15V, K20V, E35D, M36I, N37ND, R41K, D60E, I62V, L63P, I64V, A71VB
 12-19401940-30521DQ877026PINAM46L, I54V, I84V, L90ML33F, T74PL10I, V11L, I13V, R41K, K55KR, D60E, L63P, A71V, V77VI, I93LB
 12-17361736-30418DQ877138PINAG48AS, I54V, V82A, L90MK43T, G73SL10I, V11L, T12E, I15V, K20I, E35D, M36I, I62V, L63P, A71V, I72R, I85IVB
 12-20622062-30623DQ877142PINAM46I, I47V, I54L, L76V, I84V, L90MG73S, L89VL10I, V11L, I13V, I15V, Q18H, K20I, E34Q, E35D, M36I, N37ND, D60E, I62V, L63P, A71L, I72L, I93LB
 12-30943094-30509DQ877195PINAM46I, I47V, I54V, I84V, L90ML10F, Q58E, G73SV11L, I13V, K14R, I15V, K20I, M36I, R41K, D60E, I62V, L63P, A71V, I72L, I85IVB
 12-30243024-30306DQ877237PINAM46I, I54V, V82A, I84V, L90ML33F, T74PL10I, V11L, I13V, N37D, R41K, I62V, L63P, A71V, I72V, V77VI, I93LB
 48-22012201-30331DQ877854PINAI54L, I84V, L90ML33F, G73AL10I, V11L, I13V, N37H, R41K, K45R, L63P, A71V, V77I, I93LB
 48-30193019-30812DQ877929PINAM46L, I54V, V82A, L90ML10F, L33I, Q58E, L89VT4PS, V11L, I13V, L19LV, K20I, E35D, M36I, L63P, A71V, T91TCS, I93LB
 48-30573057-30325DQ877969PINAM46I, I54M, L90ML33F, Q58E, G73CL10I, V11L, I13V, K14KR, K20T, K55R, R57K, Q61E, I62V, L63E, A71T, I72T, V77I, V82IB
 48-30743074-30411DQ877983PINAM46I, I54V, V82T, I84V, L90MV32I_RR, L33F, G73S, L89VL10V, V11L, I13V, L19V, K20R, M36L, R57K, L63P, A71VB
 48-31363136-30404DQ878047PINAM46L, I54V, V82A, I84V, L90ML33F, G73S, L89VL10I, V11L, I13V, K14RT, G16GA, E34EQ, I62V, L63P, A71V, I72E, V77I, P79SB
 48-31763176-30425DQ878085PINAI47V, G48V, I54M, L76V, V82C, L90MF53L, G73A, L89VL10I, V11L, I13V, G16A, K20V, E34Q, N37D, L63P, H69Y, A71V, V77I, I93LB
 48-31883188-30505DQ878096PINAV32I, M46I, I47V, I54M, V82A, L90ML33FL10I, V11L, I13V, E34Q, N37D, L63P, I66IV, A71IL, V77I, I93LB
 48-31993199-30507DQ878109PINAM46I, I47V, I54L, I84V, L90MG73TL10I, V11L, I15V, Q18H, L19P, K20I, A22V, E34Q, M36I, K55R, L63P, I64V, A71V, I72L, I85VB
 48-32503250-30627DQ878154PINAI54V, V82A, L90ML33IV, F53FL, G73S, L89VL10V, V11L, I13V, K20M, A22V, M36I, R41K, K55KR, D60E, Q61N, I62V, L63P, A71I, I72T, I93LB
 48-40474047-30625DQ878280PINAM46I, I54V, V82T, I84V, L90MQ58E, G73S, L89VL10I, V11L, I15V, G16A, K20IT, E21Q, M36MI, R41K, D60E, Q61D, L63P, A71V, I72T, I85V, T91CS, I93LB
 48-41044104-30224DQ878334PINAM46I, I54V, V82A, I84V, L90ML33F, F53FL, Q58ET4S, L10I, V11L, I13V, G16E, L19I, M36I, Q61R, L63T, L89I, T91SB
 48-41294129-30318DQ878360PI, RTV, TPV>1V32I, M46I, I47V, I54L, I84V, L90ML33F, F53FL, Q58E, T74PL10I, V11L, I13V, K20R, E34Q, E35D, M36I, R41Q, K55KR, L63P, A71V, I72V, V77I, I93LB
 48-41634163-30403DQ878396PINAM46I, I54V, I84V, L90ML33I, Q58E, T74PL10I, V11L, I13V, Q18H, A22V, E35D, M36I, N37D, I62V, L63P, H69R, A71V, Q92KB
 48-42284228-30430DQ878461PINAM46I, I54V, V82T, I84V, L90MK43TL10I, V11L, I13V, G16A, N37D, F53W, L63P, I64V, A71V, T91SB
 48-42374237-30508DQ878468PINAM46I, I54V, I84V, L90MG73TL10I, V11L, I15V, K20I, E35D, M36I, I62V, L63P, A71V, I85VB
 48-42594259-30530DQ878491PINAV32I, M46I, I47V, I54M, I84V, L90ML33FL10I, V11L, N37S, L63P, A71L, I72IV, V77I, I93LB
 48-60156015-30317DQ878612PINAM46I, I54V, I84V, L90ML10F, G73SV11L, I13V, K14R, I15V, K20I, I62V, L63P, A71V, I72LB
  6015-30904DQ878614PI, RTV, TPV>24M46I, I54A, I84V, L90ML10FI, G73S, L89VV11L, I13V, K14KR, I15V, K20I, L33V, I62V, L63P, A71V, I72LB
  6015-40805DQ878613PI, RTV, TPV>72M46I, I54A, I84V, L90MK43KT, G73S, L89VL10IV, V11L, I13V, K14R, I15V, K20I, L33V, D60DE, I62V, L63P, A71V, I72LB
 48-60626062-30728DQ878660PINAM46I, I47IV, I54V, V82T, I84V, L90MG73ST, L89LVL10I, V11L, I15V, G16A, L19V, K20I, M36I, L63P, A71V, I72L, I85VB
 48-61766176-30710DQ878748PINAI54V, V82T, I84V, L90ML10F, L89VV11L, T12P, I13V, Q18H, K20I, M36I, N37D, R41K, K55R, I62V, L63P, A71V, T74S, T91S, Q92KB
 48-70347034-30812DQ878913PINAM46I, I54V, L76V, I84V, L90ML33I, G73S, L89VL10I, V11L, I13V, I15V, K20I, M36I, K55KR, R57RK, I62V, L63P, A71V, I72MB
 48-90369036-30825DQ877498PINAM46I, I54V, I84V, L90ML10F, G73SV11L, T12P, I15V, G17E, Q18H, K20I, M36MI, L63P, A71V, I72L, I85V, I93LB
 48-92559255-30911DQ877606PINAM46I, I47V, I54L, I84V, L90ML10F, L33F, K43KT, T74PV11L, I13V, E34Q, I62V, L63P, H69R, A71V, I72V, V77VI, I93LB
 48-80218021-30806DQ879064PINAM46I, I47V, I54M, I84V, L90ML10F, K43T, G73S, L89VV11L, T12N, I15V, L19LP, K20I, E35N, M36I, N37E, I62V, L63P, A71I, I72KR, V77I, I85V, I93LB
Cardoso (2009)3095BRGO3095FJ638442PINAI50V, I54V, V82A, L90MK43T, F53L, G73A, L89VL10IV, V11L, I13V, I15V, G16A, L19I, K20I, E35D, M36I, K55R, D60E, I62V, L63P, A71VB
 3124BRGO3124FJ638456PINAM46I, I54V, L76V, I84V, L90ML33FL10I, V11L, K20R, E34N, E35D, M36I, R41K, K55R, R57K, D60E, I62V, L63P, A71V, I72T, I93LB
Rhee (2009)CA1524CA63895FJ983143SQV, RTV, APV, LPV429G48M, I54V, V82A, I84VF53LL10I, V11L, I13V, K14KR, A22V, E35D, M36I, N37D, I62V, L63P, A71V, T74S, T91S, Q92KB
 CA1590CA57673FJ983145IDV, SQV, RTV, NFV, APV467M46I, I50V, I54V, V82L, L90ML33F, G73T, L89VL10I, V11L, T12E, I13V, Q18QH, L19M, M36I, R41K, L63P, A71V, V77I, I93LB
Dau (2010)06500A06500AGU581756PINAM46I, I54V, L76LV, V82VFI, L90ML33I, G73C, L89VL10I, V11L, I13V, K20V, M36I, P39T, I62V, L63P, I64V, T74S, I93ILB
 06981A06981AGU581807PINAM46I, I54V, V82AL10F, L89VV11L, I13V, L19Q, K20I, M36I, L63P, H69K, K70R, A71T, T91SB
 07893A07893AGU581880PINAI54M, L76V, I84V, L90ML33I, G73S, L89VL10I, V11L, I13V, Q18H, K20V, M36IL, I62V, L63P, A71IVB
 08255A08255AGU581902PINAI54A, V82A, L90ML33F, K43TL10I, V11L, I13V, K14KR, I15V, K20R, E34HKNQ, E35D, M36I, N37NI, R41K, D60E, I62V, L63PQ, I64V, H69HY, A71V, Q92K, I93LB
 09065A09065AGU581957PINAI54A, V82A, L90ML33F, K43TL10I, V11L, I13V, K14KR, I15V, K20R, E34N, E35D, M36I, R41K, D60E, I62V, L63PQ, I64V, H69HY, A71V, Q92K, I93LB
 09756A09756AGU581981PINAI54A, V82A, L90ML33F, K43TL10I, V11L, I13V, K14KR, I15V, K20R, E34N, E35D, M36I, P39PS, R41K, D60E, I62V, L63P, I64V, H69Y, A71V, Q92K, I93LB
 10025A10025AGU581992PINAM46I, I54V, V82A, I84V, L90ML33F, T74PL10I, V11L, I13V, N37D, R41K, I62V, L63P, A71V, I72V, V77VI, I93LB
Knops (2010)ID1318ID1318-GT2GU271163SQV, NFV, IDV, APV, LPV42M46I, I54V, L76V, L90MG73S, L89VL10I, V11L, I13V, I15V, L19Q, K20I, E35D, M36I, D60E, I62V, L63P, A71V, I93LB
Rangel (2010)HIV249bHIV249bGU807507PINAV32I, I47V, I54L, I84V, L90ML33F, T74PL10I, V11L, I13V, G16A, K20R, E35D, M36I, K55N, R57K, I62V, L63P, A71V, I72V, V82IB