<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L90M
Rx >= 1 PI
IncludeMixtures No
References 6
Patients 14
Isolates 19
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M35M35AY010399NFV M46I, L90M L10I, I13V, K14R, G16E, K20I, E35DN, M36I, I62IV, L63S, C67D, H69R, I72T, L89M, I93IMA
Montes (2004)MB_patSAN01_SANC718AJ577992SQV, IDV, RTV143M46I, I84V, L90MG73S, L89VL10V, I13V, G16A, K20R, E35D, M36I, N37E, R41K, D60E, I62V, L63P, H69KA
Non-B Workgroup (2005)TK2012TK2012 RTV, IDV, SQV186I54V, L90M L10V, I13V, K14R, I15V, K20R, E35D, M36I, R41K, R57K, I62V, H69K, T74S, L89IA
 TK3001TK3001 SQV90L90ML33FI13V, K14R, K20T, M36I, R41K, K43N, R57K, H69K, V82I, I85V, L89MA
 TK3017TK3017 RTV174L90M L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, L89MA
  TK3017a RTV222L90M L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, L63T, H69K, L89MA
  TK3017b RTV230L90M L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, L63T, H69K, L89MA
  TK3017c RTV249L90M L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, L63T, H69K, L89MA
 TK3029TK3029 SQV, NFV149L90M L10V, I13V, K20T, E35D, M36I, R41K, H69K, T74S, L89IA
 TK5005TK5005 SQV, IDV, RTV, NFV, LPV180G48V, I54T, V82A, L90M L10I, I13V, K14R, G17D, K20R, E34N, E35D, M36I, R41K, R57K, D60E, I62V, L63P, H69K, A71V, L89IA
  TK5005a SQV, IDV, RTV, NFV, LPV196G48V, I54T, L90M L10I, I13V, K14R, G17D, K20R, E34N, E35D, M36I, R41K, R57K, D60E, I62V, L63P, H69K, A71IV, L89I, I93IMA
Weber (2005)89M262689M2626AY677414SQV, NFV, RTV261I54V, L90MF53L, L89VL10I, I13V, K14R, K20I, E35D, M36I, N37E, R41K, R57K, H69K, A71V, T74SA
Baxter (2006)12-21202120-30715DQ876783PINAM46I, I47V, L90ML10F, L33I, F53L, G73GS, N88G, L89VI13V, K14R, K20T, E35D, M36I, R41K, R57K, I62V, L63P, H69K, A71IA
  2120-40510DQ876754PI, RTV, TPV>43M46I, I47V, L90ML10F, L33I, F53L, G73S, N88G, L89VI13V, K14R, K20T, E35D, M36I, R41K, R57K, I62V, L63P, H69K, A71IA
 48-12021202-30702DQ877746PINAI54V, V82A, L90ML33F, N83DI13V, G16E, K20R, E35D, M36I, N37D, R41K, R57RK, L63N, H69K, K70R, L89I, T91V, I93LA
 48-42174217-30915DQ878451PINAM46L, I54V, I84V, L90ML33F, K43T, N88GL10I, I13V, K14R, K20R, E21Q, E35D, M36I, N37D, Q61N, I62V, L63Q, H69K, A71L, T74S, Q92R, I93MA
 48-50215021-30606DQ878555PINAI54V, V82F, I84IV, L90ML33F, F53LL10I, V11L, I13V, I15V, G16E, L19P, K20I, E35N, M36I, K45V, L63T, H69K, L89MA
 48-50325032-30421DQ878558PINAI54V, L90ML10F, L33I, L89VI13V, E35D, M36I, R41K, R57K, I62IV, L63LP, H69KA
Jones (2012)199883199883JN671186PINAM46I, I54V, V82A, L90MN88DL10I, I13V, I15V, L19I, K20I, E35D, M36I, N37K, R41K, K45R, K55R, R57K, Q61N, L63P, C67F, A71T, I72EA