<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L89T
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 9
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M28M28AY010391NFV   I13V, L19LIV, K20I, L23LV, E35D, M36I, R41K, P44PS, L63P, H69K, A71AITV, L89TA
 NY_M72M72AY010434IDV M46MI, I84V I13V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89TA
Chantratita (2002)GEN13GEN13AF191198PINA  I13V, G16E, K20I, E35D, M36I, R41K, K55N, R57G, H69K, L89TA
Vergne (2003)VL00SN69HPD00SN69AJ583752IDV I84VG73SI13V, E35D, M36I, R41K, K45R, R57K, L63P, H69K, A71V, L89TA
Non-B Workgroup (2005)TK1009TK1009 IDV, NFV, RTV177M46ML I13V, K14KR, E35D, M36I, R41K, K45KR, R57RK, L63P, H69KQ, A71AV, L89TA
 TK4007TK4007 NFV178M46I I13V, E35D, M36I, R41K, R57K, L63P, H69K, A71AV, L89TA
Weber (2005)M50457M50457AY677433NFV94  L10I, T12S, I13V, K14KR, I15IV, K20I, E35D, M36I, N37S, R41K, K45R, H69K, A71V, L89TA
Baxter (2006)48-50315031-30421DQ878557PINAM46I, I54V, V82AG73SI13V, I15V, K20I, E35D, M36I, Q61H, L63D, H69K, A71V, L89TA
Konou (2015)H826H826KT316026PINAM46IF53LL10V, I13V, K20T, E34Q, E35D, M36V, R41K, L63P, H69K, A71V, T74S, V77I, L89TA