Protease Inhibitors

HOME Genotype-Rx Genotype-Pheno Genotype-Clinical hivdb program

Protease Inhibitors

Subtype	A
Gene	PR
Mutation	L89M
Rx	>= 1 PI
IncludeMixtures	No

References	31
Patients	139
Isolates	162

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	Wks	PIMajorDRMs	PIMinorDRMs	OtherMut	Subtype
Gonzales (2001)	CA6428	CA16183	AF331690	NFV	41			I13V, K14R, I15V, E35D, M36I, R41K, L63M, H69K, L89M	A
		CA24095		NFV, LPV	123			I13V, E35D, M36I, R41K, L63M, H69K, L89M	A
Weidle (2001)	PW_UG4399	PW_UG4399a		RTV	69	V82A	L33F	L10V, I13V, K20R, E35D, M36I, R41K, R57K, C67Y, H69K, L89M	A
	PW_UG463	PW_UG463a		IDV	13			I13V, E35D, M36I, R41K, L63Q, H69K, L89M	A
	PW_UG471	PW_UG471a	AY900678	SQV	13			I13V, G16E, K20R, E35D, M36I, R41K, R57K, H69K, K70R, L89M	A
	PW_UG473	PW_UG473	AF358758	RTV	40			I13V, K20I, E35D, M36I, R41K, H69K, L89M	A
Yahi (2001)	NY_M35	M35	AY010399	NFV		M46I, L90M		L10I, I13V, K14R, G16E, K20I, E35DN, M36I, I62IV, L63S, C67D, H69R, I72T, L89M, I93IM	A
	NY_M36	M36	AY010400	NFV				G16A, E35D, M36I, R41K, H69K, L89M	A
	NY_M71	M71	AY010433	IDV				L10V, I13V, K14R, G16E, E35D, M36I, R41K, R57K, H69K, L89M	A
	NY_M73	M73	AY010435	IDV				L10V, I13V, K14R, G16E, K20KI, E35D, M36I, R41K, R57K, H69K, T74TA, L89M	A
Gibb (2002)	DMG102	102_w51		NFV	52		V32L	I13V, E35D, M36I, R41K, K45R, R57K, L63P, H69K, L89M	A
	DMG106	106_w41		NFV	41	M46L	N83D	I13V, G16A, K20R, A22V, E35D, M36I, R41K, R57K, I64IV, H69K, L89M	A
		106_w43		NFV	43			I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M	A
	DMG16	16_w16		NFV	15			I13V, K14R, E35D, M36I, N37D, R41K, K45R, R57K, H69K, L89M	A
		16_w32		NFV	30			I13V, K14R, E35D, M36I, N37D, R41K, K45R, R57K, H69K, L89M	A
	DMG65	65_w9		NFV	9			I13V, G16A, K20R, E35D, M36I, R41K, R57K, H69K, A71AV, L89M	A
	DMG68	68_w27		NFV	27	M46MI		I13V, G16A, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
		68_w30		NFV	30			I13V, G16A, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	DMG70	70_w27		NFV	27			I13V, G16E, E35D, M36I, R41K, L63V, G68GE, H69K, L89M, T91V, I93L	A
	DMG77	77_w19		NFV	14			I13V, E35D, M36I, R41K, R57K, H69K, L89M	A
		77_w42		NFV	37			I13V, E35D, M36I, R41K, R57K, H69K, L89M	A
		77_w67		NFV	59			I13V, E35D, M36I, R41K, R57K, H69K, L89M	A
	DMG86	86_w71		NFV	54			I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M	A
	DMG98	98_w29		NFV	29			I13V, E35D, M36I, R41K, K45R, R57K, L63P, H69K, L89M	A
		98_w55		NFV	55			I13V, K20R, E35D, M36I, N37D, R41K, Q61QE, H69K, I72IV, L89M	A
Vergne (2002)	LV04B	LV04B	AJ313406	IDV	74			I13V, G17E, K20I, M36I, N37D, L63P, H69K, K70R, L89M	A
Holguin (2003)	SP_LP5	SP_LP5	AF455604	PI	NA			L10I, I13V, K14R, E35D, M36I, R41K, L63V, H69K, L89M	A
Shafer (2003)	A384_0983	0983b	EF548169	NFV	43			L10V, I13V, K20T, E35D, M36I, R41K, R57K, H69K, L89M, I93M	A
Weber (2003)	3M	IRIS3M-24	AY140812	SQV, RTV	22			I13V, E35D, M36I, R41K, H69K, L89M	A
	5W	IRIS5W-48	AY140814	IDV	48			L5F, I13V, E35D, M36I, R41K, R57K, H69K, L89M	A
	SI	IRIS6I-48	AY140815	SQV, RTV	52			I13V, E35D, M36I, R41K, R57K, H69K, V77I, L89M	A
Gomez-Carrillo (2004)	103396	103396	AY365678	PI	NA	I54V		I13V, K20I, E35D, M36I, N37D, R41K, I62V, L63V, I66F, G68E, H69R, L89M, T91V	A
	111780	111780	AY365851	PI	NA			I13V, E35D, M36I, N37D, R41K, L63V, H69K, K70R, L89M, T91V	A
Grossman (2004)	IL88	IL88	AY529535	NFV	65			A22R, E35D, M36I, R41K, H69K, L89M, I93L	A
Montes (2004)	MB_patSAA	00_SAA713	AJ577989	NFV, SQV	21			L10I, I13V, I15V, E35D, M36I, R41K, H69K, L89M	A
		01_SAA704	AJ577990	NFV, SQV	21			L10I, I13V, I15V, E35D, M36I, R41K, H69K, L89M	A
	MB_patBES	00_BES703	AJ577738	SQV	104			I13V, I15S, G16R, G17R, E35D, M36I, R41K, R57K, H69K, L89M	A
		02_BES706	AJ577740	SQV, RTV	108			I13V, K14R, I15V, E35D, M36I, R41K, R57K, H69K, L89M, G94A	A
Non-B Workgroup (2005)	UK847b	UK847b	AY900783	NFV, LPV				I13V, K14R, E35D, M36I, R41K, R57K, L63P, H69K, L89M	A
	UK1516	UK1516		PI, LPV	NA	I54L		L10I, I13V, G16E, K20T, E35D, M36I, R41K, R57K, L63T, H69K, T74S, V82VI, I85V, L89M	A
	IL276	IL276		IDV	81			L10I, E35D, M36I, R41K, R57K, L63T, H69R, L89M, I93L	A
	PL9728	60099	AY901076	IDV, RTV, ATV		I54V, V82A	L33I, F53L, N83D	L10Y, I13V, G16E, K20R, A22AV, E35DN, M36I, N37ND, R41RK, L63T, H69K, T74S, L89M, T91A	A
	TK1001	TK1001		IDV	129			L10I, I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M	A
	TK1005	TK1005		RTV, IDV, NFV	201			I13V, E35D, M36I, N37ND, R41K, R57RK, L63LI, H69K, L89M	A
	TK1010	TK1010a		IDV, Unknown	>229		L10F	T12I, I13V, G16E, E35D, M36I, R41K, R57K, H69K, K70R, L89M	A
		TK1010b		IDV, Unknown	>229		L10F	T12I, I13V, G16E, E35D, M36I, R41K, R57K, I62V, L63H, H69K, K70R, L89M	A
	TK1025	TK1025		IDV, LPV	180			I13V, I15V, E35D, M36I, R41K, K45R, R57K, Q61E, I64M, H69K, K70Q, I72IV, L89M	A
	TK1030	TK1030		SQV, RTV, IDV	146			L10I, I13V, G16E, E35D, M36I, R41K, R57K, L63S, H69K, L89M	A
		TK1030a		SQV, RTV, IDV	305			L10V, I13V, G16GE, E35D, M36I, R41K, R57K, L63PS, H69K, L89M	A
	TK2004	TK2004		IDV	181			I13V, K20R, E35D, M36I, R41K, R57K, H69K, K70R, L89M	A
	TK2007	TK2007		SQV, RTV	69			I13V, E35D, M36I, N37ND, R41K, K45R, R57K, H69K, L89M	A
	TK2017	TK2017		NFV	35			I13V, E35D, M36I, R41K, R57K, H69K, V77I, L89M	A
	TK2021	TK2021		NFV	88			I13V, I15V, E35D, M36I, R41K, R57RK, H69K, K70R, L89M	A
	TK2022	TK2022		SQV, RTV	12			L10X, I13V, I15IV, L19LI, E35D, M36I, R41K, R57K, L63X, H69K, L89M	A
	TK2027	TK2027		IDV, RTV	90			I13V, E35D, M36I, R41K, K45R, R57K, H69K, L89M	A
	TK2029	TK2029		IDV	39			L10I, I13V, K14R, G16GE, E35D, M36I, R41K, K45R, R57K, L63P, H69K, V77I, L89M	A
	TK3001	TK3001		SQV	90	L90M	L33F	I13V, K14R, K20T, M36I, R41K, K43N, R57K, H69K, V82I, I85V, L89M	A
	TK3017	TK3017		RTV	174	L90M		L10V, I13V, G16E, K20R, E35D, M36I, R41K, L63T, H69K, L89M	A
		TK3017a		RTV	222	L90M		L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, L63T, H69K, L89M	A
		TK3017b		RTV	230	L90M		L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, L63T, H69K, L89M	A
		TK3017c		RTV	249	L90M		L10V, I13V, G16E, K20R, E35D, M36I, P39PS, R41K, L63T, H69K, L89M	A
	TK3029	TK3029a		SQV, NFV, LPV	207			I13V, E35D, M36I, R41K, H69K, L89M	A
	TK3030	TK3030		SQV, NFV	250			I13V, E35D, M36I, N37NT, R41K, K45R, R57K, H69K, L89M, I93IM	A
	TK3033	TK3033		NFV	1			I13V, I15IV, E35D, M36I, R41K, R57K, H69K, L89M	A
		TK3033a		NFV	1			I13V, K20KR, E35D, M36I, R41K, R57K, H69K, L89M	A
	TK4003	TK4003		NFV	116		N83D	L10V, I13V, K14R, G16E, E35D, M36I, R41K, K45R, R57K, L63T, H69K, K70R, L89M, I93L	A
	TK4009	TK4009		IDV	336			I13V, K14R, G16E, K20R, E35D, M36I, R41K, H69K, L89M, I93L	A
	TK4012	TK4012		SQV, RTV	4			K14R, E35D, M36I, N37D, R41K, R57K, H69K, L89M	A
	TK4013	TK4013		SQV, RTV, NFV	213			I13V, K14R, I15V, E35D, M36I, R41K, R57K, H69K, L89M	A
	TK5008	TK5008		IDV	93			I13V, G16E, K20R, E35D, M36I, R41K, R57K, H69K, K70R, L89M	A
	TK5011	TK5011		IDV	34			L10V, I13IV, K14KR, E35D, M36I, R41K, R57K, H69K, L89M	A
	TK5012	TK5012		IDV	54			L10I, I13V, K14R, G16E, K20R, E35D, M36I, R41K, L63T, H69K, L89M	A
		TK5012a		IDV, LPV	152			L10I, I13V, K14KR, G16E, K20R, E35D, M36I, R41K, L63T, H69K, L89M	A
		TK5012b		IDV, LPV	191			L10IV, I13V, K14KR, G16E, K20R, E35D, M36I, R41K, L63T, H69K, L89M	A
		TK5012c		IDV, LPV	215			L10I, I13V, K14KR, G16E, K20R, D25DG, E35D, M36I, R41K, L63ST, H69K, L89M	A
	PL43110	75401		IDV	208			K20R, E35D, M36I, N37D, R41K, I62V, L63T, H69K, L89M	A
Weber (2005)	F76135	F76135	AY677380	RTV	65			Q7QH, T12V, K14R, K20R, E21K, E35D, M36I, N37D, R41K, R57K, L63V, H69K, L89M	A
	F45753	F45753	AY677422	SQV, NFV	258			L10I, I13V, G16E, K20R, E35D, M36I, P39S, R41K, H69K, L89M	A
	M76115	M76115	AY677424	LPV	19			I13V, I15V, E35D, M36I, N37E, R41K, K45R, R57K, H69K, L89M	A
	M49551	M49551	AY677385	RTV	96			T4TP, I13V, G16E, E35D, M36I, R41K, H69K, L89M	A
	F46097	F46097	AY677388	NFV, SQV, RTV	148			T4TP, I13V, K14R, Q18QH, E35D, M36I, R41K, R57K, L63P, H69K, L89M	A
	F51354	F51354	AY677444	SQV, NFV	115			L10V, I13V, K14R, G16E, K20T, E35D, M36I, R41K, R57K, L63T, H69K, I72T, T74TA, L89M	A
	M36781	M36781-2	AY714402	Unknown, LPV	>8			I13V, G16E, E35D, M36I, R41K, K45R, R57K, H69K, I72K, L89M	A
	F65588	F65588	AY677449	NFV	46			I13V, E35D, M36I, R41K, K45R, R57K, H69K, V82I, L89M	A
	M41971	M41971	AY677401	IDV, NFV, LPV	181	I54V, V82A	L10F, L33I	T4TS, I13V, G16E, L19LI, K20R, E35D, M36I, N37D, R41K, K45V, K55T, R57K, L63H, H69K, K70R, L89M, T91TS	A
	F87084	F87084	AY677406	IDV	28			L10I, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63V, H69K, L89M	A
	F78596	F78596	AY677480	IDV	18			L10I, I13V, I15L, K20I, E35D, M36I, L63S, H69K, L89M	A
	M47502	M47502	AY677409	NFV	51	N88NS		L10I, I13V, K20KT, E35ED, M36I, R41K, L63T, I64IV, H69K, L89M	A
	M41984	M41984	AY677484	IDV	139		L33F	I13V, K14R, E35D, M36I, R41K, K43KR, R57K, H69K, L89M	A
	F40883	F40883	AY714449	NFV, Unknown, LPV	>105			I13V, I15V, K20KR, E35D, M36I, R41K, R57K, H69K, L89M	A
	F56706	F56706	AY714473	SQV, RTV	153			T12A, I13V, E35D, M36I, N37D, R41K, R57K, D60E, H69K, L89M	A
Baxter (2006)	12-2024	2024-30709	DQ876698	PI	NA	M46L, I54V	L33F, N83D	L10V, I13V, K14R, E35D, M36IL, N37ND, R41K, R57K, H69Q, L89M	A
	48-1204	1204-30709	DQ877748	PI	NA	M46I, G48Q, I54T, V82F	L33F, Q58E, N83D	L10V, I13V, G16E, E35D, M36L, P39S, R57K, I62V, L63V, H69K, T74A, L89M	A
	48-1253	1253-30605	DQ877778	PI	NA			L10V, T12TP, I13V, K14R, G16E, K20R, E35D, M36I, R41K, R57RK, Q61QE, I62IV, L63CS, H69K, L89M	A
	48-1254	1254-30617	DQ877779	PI	NA	G48V	L33F, N83D	L10LI, I13V, E35D, M36V, N37NS, P39T, R41K, R57K, L63S, H69K, L89M	A
		1254-40601	DQ877780	PI, RTV, TPV	>50		L33F	T12A, I13V, E35D, M36IV, P39AT, R41K, R57K, L63S, H69K, L89M	A
	48-3316	3316-30818	DQ878217	PI	NA	I54A, V82F		L10I, T12TK, I13V, G16A, L19LV, K20I, E35N, M36I, R41K, D60E, L63P, H69K, T74S, V77I, L89M	A
	48-4018	4018-30227	DQ878252	PI	NA	M46I	L10F, V11I, L24I, L33F, Q58E, T74P	T12TA, I13V, E35D, M36IV, N37D, I62V, L63T, H69K, K70R, I85V, L89M	A
	48-4186	4186-30408	DQ878420	PI	NA	I54V, V82A	L24I, L33I, Q58E, N83D	L10I, I13V, G16E, K20R, A22V, E35D, M36I, N37D, R41K, L63T, H69K, I72V, T74A, L89M, T91V, I93L	A
	48-5021	5021-30606	DQ878555	PI	NA	I54V, V82F, I84IV, L90M	L33F, F53L	L10I, V11L, I13V, I15V, G16E, L19P, K20I, E35N, M36I, K45V, L63T, H69K, L89M	A
	48-5035	5035-30421	DQ878561	PI	NA			T12P, I13V, K14R, E35D, M36I, R41K, K45R, R57K, L63P, H69K, K70R, L89M	A
Laurent (2006)	CK2-75	02CM-75	AM279446	IDV	39			L10V, I13V, I15V, E35D, M36I, R41K, R57K, D60E, H69K, L89M	A
Saad (2006)	MDS_02UAKV125	02UAKV125	DQ055293	SQV				I13IV, G16GA, E35D, M36I, R41K, H69K, L89M, I93L	A
Seyler (2007)	265	CS_265		IDV	66			L10V, I13V, L19P, K20I, M36I, R41K, K43R, L63LP, H69K, L89M	A
	483	CS_483		NFV	162			L10V, I13V, G16GE, E35D, M36I, R41K, H69K, K70R, L89M	A
	547	CS_547		NFV	268		G48GR, V82VD	I13V, K14R, G16GR, K20I, M36IT, R41K, L63P, H69K, L89M	A
von Wyl (2007)	27	10528715	EF449796	PI	NA			I13IV, K14KR, I15IV, E35D, M36I, R41K, L63T, H69K, L89M	A
	85	495945	EF449807	PI	NA			L10V, I13V, E35D, M36I, R41K, H69K, L89M	A
	134	5191462	EF449882	PI	NA			L10V, I13V, E35D, M36I, R41K, K45R, R57K, L63V, L89M	A
	13	662529	EF449971	PI	NA			I13V, I15V, E35D, M36I, R41K, R57K, H69K, T74S, L89M	A
Gody (2008)	Pt047	Pt047		IDV				L10V, I13V, G16E, E35D, M36I, N37D, L63AS, H69K, I72V, L89M	A
Rosen-Zvi (2008)	39	01p39-1		RTV, IDV, LPV	138			I13V, E35D, M36I, R41K, K45R, L63LP, H69K, L89M	A
		03p39-2		RTV, IDV, LPV	248			I13IV, E35D, M36I, R41K, K45R, L63LP, H69K, L89M	A
		08p39-3		RTV, IDV, LPV, ATV	479			E35D, M36I, R41K, K45R, L63P, H69K, A71T, L89M	A
Sylla (2008)	A2868	A2868_C1	EF525663	IDV				L10I, I13V, G16E, K20R, E35D, M36I, R41K, H69K, K70R, I72R, L89M	A
Koyalta (2009)	33	TCHAD-33	FJ688184	IDV	26			L10I, I13V, G16A, K20I, E35D, M36I, R41K, H69Q, L89M	A
Rhee (2009)	CA6428	CA21387	FJ983200	NFV	91			I13V, E35D, M36I, R41K, L63M, H69K, L89M	A
Steegen (2009)	BV114	BV114-1	EU872122	LPV	4			I13V, G16E, K20R, E35D, M36I, R41K, Q61H, L63T, G68E, H69K, K70R, V82I, L89M, T91V, I93L	A
	BV223	BV223-1	EU872135	LPV	4			I13V, E35D, M36I, P39Q, R41K, L63P, H69K, L89M	A
Thomson (2009)	SP_B_005	RU_SP_B_005	FJ009783	RTV, IDV, APV, LPV				K14R, G16GE, E35D, M36I, R41K, H69K, V77I, L89M, I93IL	A
	SP_B_008	RU_SP_B_008	FJ009786	LPV				L10LI, I13V, K14R, M36I, R41K, H69K, L89M	A
	SP_B_028	RU_SP_B_028	FJ009793	NFV				L10LI, I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M, I93IL	A
	SP_B_029	RU_SP_B_029	FJ009794	LPV, NFV	25			K14R, E35D, M36I, R41K, H69K, L89M, I93L	A
	SP_B_031	RU_SP_B_031	FJ009796	LPV, IDV	160			K14R, E35D, M36I, N37D, R41K, H69K, L89M	A
	SP_B_043	RU_SP_B_043	FJ009804	LPV	47			K14R, E35D, M36I, R41K, H69K, L89M	A
	SP_B_051	RU_SP_B_051	FJ009809	DRV	4			I13V, I15V, E35D, M36I, R41K, H69K, V77I, L89M, I93L	A
	SP_B_057	RU_SP_B_057	FJ009812	RTV, IDV, LPV	29			L10I, E35D, M36I, R41K, H69K, L89M	A
Hamkar (2010)	2	Ir-HIV-DR-02	GU724805	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	3	Ir-HIV-DR-03	GU724806	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	6	Ir-HIV-DR-06	GU724809	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	7	Ir-HIV-DR-07	GU724810	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	8	Ir-HIV-DR-08	GU724811	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	9	Ir-HIV-DR-09	GU724812	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	11	Ir-HIV-DR-11	GU724814	PI	NA			T12K, I13V, K14I, L19Q, K20R, E35D, M36I, R41K, G49E, R57K, H69K, L89M	A
	12	Ir-HIV-DR-12	GU724815	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	14	Ir-HIV-DR-14	GU724817	PI	NA			I13V, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	15	Ir-HIV-DR-15	GU724818	PI	NA			I13V, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	17	Ir-HIV-DR-17	GU724820	PI	NA		L23I	Q2H, T12P, K14R, K20R, E35D, M36I, R41K, L63P, H69K, L89M, I93F, T96P	A
	19	Ir-HIV-DR-19	GU724822	PI	NA			I13V, L19Q, K20R, E35D, M36I, R41K, R57K, C67Y, H69K, L89M	A
	21	Ir-HIV-DR-21	GU724824	PI	NA			I13V, L19Q, K20R, E35D, M36I, R41K, R57K, C67Y, H69K, L89M	A
	24	Ir-HIV-DR-24	GU724827	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	25	Ir-HIV-DR-25	GU724828	PI	NA			I13V, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	28	Ir-HIV-DR-28	GU724831	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	30	Ir-HIV-DR-30	GU724833	PI	NA			T12P, K14R, K20R, E35D, M36I, R41K, L63P, H69K, L89M, I93L	A
	31	Ir-HIV-DR-31	GU724834	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	34	Ir-HIV-DR-34	GU724837	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	35	Ir-HIV-DR-35	GU724838	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, R41K, R57K, H69K, L89M	A
	37	Ir-HIV-DR-37	GU724840	PI	NA			I13V, K14I, L19Q, K20R, E35D, M36I, N37F, R41K, R57K, E65G, I66V, H69K, L89M	A
	38	Ir-HIV-DR-38	GU724841	PI	NA			I13V, K14I, L19Q, K20R, A28P, E35D, M36I, R41K, R57K, H69K, L89M	A
	40	Ir-HIV-DR-40	GU724843	PI	NA			I13V, L19Q, K20R, E35D, M36I, R41K, R57K, C67Y, H69K, L89M	A
	42	Ir-HIV-DR-42	GU724845	PI	NA			I13P, K14I, L19Q, K20R, G27P, E35D, M36I, R41K, R57K, H69K, P81G, L89M	A
Charpentier (2011)	8	CP 001-259		Unknown, LPV	NA			L10LI, K14KR, E35D, M36I, R41K, I62IV, L63AV, I64IL, H69K, K70KR, I72IV, L89M	A
	32	CP 001-144		Unknown, LPV	NA			I13V, K14R, G17E, K20I, E34K, M36I, N37D, P39M, L63T, I64M, H69K, K70KR, I72T, L89M	A
	51	CP 001 2273		Unknown, LPV	NA			T12P, I13V, G16E, K20R, E35D, M36I, R41K, K55K*, L63T, E65EG, G68GE, H69KR, L89M	A
Barber (2012)	50857	50857	JQ361664	LPV		M46I, L76V, I84V		L10I, I13V, G16E, M36I, R41K, L63T, H69K, L89M	A
	67784	67784	JQ361691	LPV		I54V		I13V, G17D, K20R, E35D, M36I, R41K, R57K, D60E, I62V, L63I, H69K, L89M	A
Jones (2012)	160444	160444	JN669977	PI	NA	I54IV	L10F, F53FL	I13V, E35D, M36I, N37D, R41K, L63V, H69K, K70R, T74A, L89M, T91V	A
	178278	178278	JN670478	PI	NA	I54V, V82VA, L90LM	L10F, F53L	I13V, K20I, E35D, M36I, N37D, R41K, I62V, L63V, H69K, K70R, T74A, L89M, T91V	A
	184144	184144	JN670673	PI	NA	M46I, I50IL, I54AV, V82A	L24I, L33F, Q58E	L10I, T12N, I13V, G16GE, K20I, E35N, M36I, N37E, R41K, R57K, D60E, Q61N, L63T, I72T, L89M	A
	203362	203362	JN671308	PI	NA			L5LF, L10LP, I13V, G16E, E35D, M36I, R41K, L63V, H69K, L89M, T91V	A
Reynolds (2012)	J7227	J0722-2	JN652210	Unknown, RTV, LPV	NA			I13V, K20I, A22AV, E35N, M36I, R41K, H69K, V77I, L89M	A
Alcantara (2013)	BRGO4024	BRGO4024	JN114130	LPV				I13V, I15V, G16E, K20M, E35D, M36MI, N37K, P39T, R41K, R57K, D60E, Q61D, L63P, L89M	A

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