<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation N88S
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 9
Isolates 9
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Papa (2002)16GR16AF385360IDV M46I, N88SK43T, L89VI13V, K20I, E35DG, M36I, N37D, R41K, I62IV, H69K, A71TA
Snoeck (2002)BE18BE18AF339014NFV52N88SL89VL10M, I13V, E35D, M36I, R41K, L63P, H69K, I93LA
Non-B Workgroup (2005)PL803667027 IDV, NFV234N88SL10FG16E, K20IR, E35D, M36I, N37DE, P39PS, R41K, L63V, H69K, K70R, T74TS, L89M, T91V, I93LA
 TK4006TK4006 NFV83N88SL10FI13V, I15V, K20I, E35N, M36I, R41K, K45R, R57Q, H69K, L89IA
 TK5002TK5002 NFV189N88SL10FI13V, K14R, I15V, K20T, E35D, M36I, R41K, K45R, R57K, H69K, L89IA
Weber (2005)01M612201M6122AY677413NFV224N88SL10FI13V, K20I, E35D, M36I, R41K, H69K, L89MA
Dau (2010)11741A11741AGU582052PINAN88SL10F, L89VI13V, K20T, E35D, M36I, R41K, I62V, L63P, H69K, T74SA
Acharya (2014)DGP185DGP185KJ185355RTV, ATV M46I, I54V, V82A, N88SL24I, L33F, Q58EL5I, L10V, I13V, I15V, E35D, M36I, N37E, R41K, R57K, D60E, H69K, A71V, L89MA
Diaz (2015)RenG14395RenG14395KT745423PINAN88S I15V, K20T, E35H, M36I, P39S, R41K, R57K, Q61N, L63C, E65D, T74S, L89MA