<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation N83D
Rx >= 1 PI
IncludeMixtures No
References 5
Patients 14
Isolates 15
 
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG106106_w41 NFV41M46LN83DI13V, G16A, K20R, A22V, E35D, M36I, R41K, R57K, I64IV, H69K, L89MA
Non-B Workgroup (2005)UK1436UK1436AY900801SQV, RTV, NFV123 N83DI13V, K14R, K20R, A22V, E35D, M36I, R41K, R57K, H69K, L89I, T91AA
 UK2149UK2149AY900859Unknown, LPVNAM46I, L76V, I84VL33I, N83DL10I, I13V, A22V, E35D, M36I, N37D, R41K, K45R, R57K, L63P, A71V, L89IA
 PL972860099AY901076IDV, RTV, ATV I54V, V82AL33I, F53L, N83DL10Y, I13V, G16E, K20R, A22AV, E35DN, M36I, N37ND, R41RK, L63T, H69K, T74S, L89M, T91AA
 TK2002TK2002 IDV, RTV273M46MI, V82ATL33I, N83DL10LI, I13V, K14R, A22AV, E35D, M36I, R41K, R57K, H69K, L89IMA
 TK4003TK4003 NFV116 N83DL10V, I13V, K14R, G16E, E35D, M36I, R41K, K45R, R57K, L63T, H69K, K70R, L89M, I93LA
  TK4003a NFV215I54VL33I, N83DL10V, I13V, K14R, G16E, A22V, E35D, M36I, R41K, K45R, L63T, H69R, K70R, L89IA
Weber (2005)F73291F73291AY677477NFV195M46LL33I, N83DL10V, I13V, A22V, E35D, M36I, R41K, I62V, L63PS, H69K, T74S, L89I, I93LA
Baxter (2006)12-20242024-30709DQ876698PINAM46L, I54VL33F, N83DL10V, I13V, K14R, E35D, M36IL, N37ND, R41K, R57K, H69Q, L89MA
 48-12021202-30702DQ877746PINAI54V, V82A, L90ML33F, N83DI13V, G16E, K20R, E35D, M36I, N37D, R41K, R57RK, L63N, H69K, K70R, L89I, T91V, I93LA
 48-12041204-30709DQ877748PINAM46I, G48Q, I54T, V82FL33F, Q58E, N83DL10V, I13V, G16E, E35D, M36L, P39S, R57K, I62V, L63V, H69K, T74A, L89MA
 48-12541254-30617DQ877779PINAG48VL33F, N83DL10LI, I13V, E35D, M36V, N37NS, P39T, R41K, R57K, L63S, H69K, L89MA
 48-30453045-30317DQ877957PINAG48V, I54S, V82AL33F, Q58E, N83DL10V, I13V, K14R, I15V, M36L, R41RK, D60DE, I62IV, L63P, H69K, I85V, L89I, T91TSA
 48-41864186-30408DQ878420PINAI54V, V82AL24I, L33I, Q58E, N83DL10I, I13V, G16E, K20R, A22V, E35D, M36I, N37D, R41K, L63T, H69K, I72V, T74A, L89M, T91V, I93LA
von Wyl (2007)70496347EF449835PINA N83DI13V, M36L, N37T, R41K, H69K, L89IA