<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation V82I
Rx PI-naive
IncludeMixtures No
References 35
Patients 58
Isolates 59
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Eshleman (2004)ESH_Pat157ESH520AY435296None   I13V, I15IL, E35D, M36I, N37D, R41K, C67CG, H69K, V82I, L89MA
Non-B Workgroup (2005)TK5001TK5001 None   L10I, I13V, K14R, E35D, M36I, R41K, R57K, L63T, H69K, V82I, L89MA
Weber (2005)F54577F54577AY677382None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
Vidal (2006)NV_KSTB00702.KSTB007AM040992None   I13V, K14R, K20I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
Zarandia (2006)MZ_03GEMZ03803GEMZ038DQ205292None   L10I, I13V, E35D, M36I, R41K, L63V, C67CY, H69K, V82I, N83X, L89MA
Brumme (2007)1365PRRT_1365EF368675None   I13V, K14R, K20I, M36I, R41K, H69K, V82I, L89MA
Eyzaguirre (2007)KZ30023503KZ300235EF576767None   I13V, K14R, E35D, M36I, R41K, H69K, V82I, L89M, I93LA
Liu (2007)fj53fj53EF432686None   L10I, I13V, E35D, M36I, R41K, K43R, L63P, H69K, V82I, L89M, I93V, F99LA
Razafindratsimandresy (2007)1111HIV-SEYEF143503None   I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 1212HIV-SEYEF143504None   I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 1313HIV-SEYEF143505None   I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 1717HIV-SEYEF143509None   I13V, K14R, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 1919HIV-SEYEF143511None   I13V, G16A, E35D, M36I, R41K, R57K, I62V, H69K, V75I, V82I, L89MA
 2121HIV-SEYEF143513None   I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 2929HIV-SEYEF143520None   I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
Nyombi (2008)TBK018TBK018EU251725None   I13V, K20I, E35D, M36I, R41K, R57K, L63P, H69K, I72L, V82I, L89MA
 TBK093TBK093EU251775None   T12S, I13V, I15V, L19I, E35D, R41K, L63T, H69KQ, A71T, V82I, I93LA
Vercauteren (2009)pt2162245005610GQ398862None   L10I, T12R, I13V, I15V, L19I, K20I, E35D, M36I, N37D, R41K, H69Q, V82I, L89MA
 pt5759510400631GQ400449None   L10I, T12A, I13V, I15K, G16E, K20R, E21D, E35D, M36I, L63A, C67CY, H69K, K70R, V82I, L89MA
Ndembi (2010)DT2829_05_P12829GQ409610None   I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
Hamers (2011)CP076301537CP076301537HQ993581None   I13V, E35D, M36I, R41K, R57K, L63PT, H69K, V77I, V82I, L89MA
 CP076301760CP076301760HQ993748None   I13V, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, K70R, V82I, L89M, T91V, I93LA
 CP076304140CP076304140HQ993876None   L10I, I13V, G16A, M36I, R41K, K43R, R57K, L63T, H69KN, K70R, V82I, L89IA
 CP076303076CP076303076HQ995254None   I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MA
Dvali (2012)R006R006FJ178577None   R8RP, I13V, E35D, M36I, R41K, H69K, V82I, L89M, I93LA
Nazziwa (2012)51191015119101JX499006None   I13V, K14R, E35D, M36I, R41K, R57K, I62V, L63H, H69K, V82I, L89MA
Serrano (2012)20106934522010693452JQ616891None  V11IL10I, T12K, I13V, L19V, M36I, N37D, R41K, I62V, L63A, H69Q, V82I, L89MA
Ssemwanga (2012)3272HR3272HRJF800198None   I13V, K20I, E21K, M36I, R41K, L63N, H69K, V82I, L89MA
 8651HR8651HRJF800231None   T12S, I15V, E35D, M36I, N37D, R57K, L63T, H69K, V82IA
Feng (2013)GX070005GX070005JX112830None   I13V, K14R, G16E, E35D, M36I, R41K, K45R, H69K, V82I, L89MA
Frentz (2013)EHR-07924EHR-07924JX299669None   I13V, I15V, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
Hassan (2013)RS09000931RS09000931HQ441673None   I13V, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, K70R, V82I, L89M, T91V, I93LA
 RS11000320RS11000320JQ698398None   T12P, I13V, G16E, K20R, E35D, M36I, R41K, Q61E, L63V, G68E, H69K, K70R, V82I, L89M, T91V, I93LA
Acharya (2014)DGP049DGP049KJ185219None   I13V, K14R, E35D, M36I, N37D, R41K, R57K, I62V, I64L, H69K, V82I, L89MA
Aghokeng (2014)CM-3-010CM-3-010KC350336None   I13V, I15V, M36I, R41K, L63A, H69K, V82I, L89MA
Lee (2014)MBA1135MBA1135KJ906833None   I13V, K20R, M36I, R41K, R57K, L63P, H69K, V82I, L89MA
 MBA1430MBA1430KJ907113None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
 MBA1029MBA1029KJ906732None   I13V, K14R, K20I, L23LV, E35D, M36I, R41K, H69K, K70KR, V82I, L89MA
 AMU009AMU009KJ906633None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
Meixenberger (2014)12-0021112-00211KJ771681None   K20R, E35D, M36I, R41K, L63P, I64L, H69K, V82I, L89M, I93LA
 10-0276710-02767KJ771432None   K20R, E35D, M36I, R41K, L63P, I64L, H69K, V82I, L89M, I93LA
Budambula (2015)MK38MK38KP792032None   I13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, Q61H, I64M, H69K, I72E, V82I, L89MA
 MK60MK60KP792054None   I13V, M36I, R41K, I62V, H69K, V82I, L89MA
Meini (2015)111128111128KM438261None   T12TA, I13V, R41K, H69K, K70R, V77I, V82I, L89MA
Billings (2016)CO0329V1CO0329V1KX907342None   I13V, K14R, E35D, M36I, R41K, K45R, R57K, L63S, H69K, V82I, L89MA
Boillot (2016)ALO03ALO03KT315948None   T12P, I13V, L19I, E35D, M36I, R57K, L63P, C67Y, H69K, V82I, L89MA
Castley (2016)P098043942P098043942KT228564None   I15V, K20R, E35D, M36I, R41K, I62V, C67E, H69K, V82I, L89MA
 P149402802LP149402802LKT229075None   T12P, I13V, L19Q, M36I, L63P, H69K, K70R, V82I, L89I, F99XA
Chow (2016)MYNBB026MYNBB026KU535915None   L10I, T12I, I13V, M36I, N37D, R41K, L63P, H69K, K70R, V82I, L89IA
 MYNBB050MYNBB050KU535931None   L10V, T12I, I13V, M36I, R41K, L63P, H69K, K70R, V82I, L89IA
 MYNBB072MYNBB072KU535953None   T12I, I13V, M36I, N37D, R41K, L63P, H69K, K70R, V82I, L89I, I93LA
 MYNBB058MYNBB058KU535939None   T12I, I13V, E35D, M36I, N37D, R41K, L63P, H69K, K70R, V82I, L89I, I93LA
Hattori (2016)C09_110862C09-51110862-1AB865268None   I13V, I15V, E35D, M36I, R41K, K45R, R57K, L63T, H69K, V82I, L89MA
Onsongo (2016)114114KM376206None   D25H, E35D, M36I, N37D, R57K, L63P, H69K, V77I, V82I, L89MA
Otecko (2016)405478405478KX306401None   I13V, K14N, G16E, L19I, E35D, M36I, N37H, R41K, L63N, H69K, I72T, V82I, L89M, T91V, I93LA
 402775402775KX306387None   I13V, K14R, E35D, M36I, N37E, R41K, R57K, C67Y, H69K, K70R, V82I, L89MA
Pouran Yousef (2016)433210-02767KX466977None   K20R, E35D, M36I, R41K, L63P, I64L, H69K, V82I, L89M, I93LA
  12-00211KX466978None   K20R, E35D, M36I, R41K, L63P, I64L, H69K, V82I, L89M, I93LA
Van Tran (2016)VI-417VI-417LC101257None   I13V, L19V, M36I, R41K, H69K, V82I, L89MA