<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation V82I
Rx PI-naive
IncludeMixtures No
References 42
Patients 65
Isolates 65
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Pandrea (2002)IP_96CIRMF6296CIRMF62AY140634None   E35D, M36I, R41K, I62V, C67E, H69K, V82I, L89MA
Eshleman (2004)ESH_Pat157ESH520AY435296None   I13V, I15IL, E35D, M36I, N37D, R41K, C67CG, H69K, V82I, L89MA
Non-B Workgroup (2005)TK5001TK5001 None   L10I, I13V, K14R, E35D, M36I, R41K, R57K, L63T, H69K, V82I, L89MA
Weber (2005)F54577F54577AY677382None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
Vidal (2006)NV_KSTB00702.KSTB007AM040992None   I13V, K14R, K20I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
Zarandia (2006)MZ_03GEMZ03803GEMZ038DQ205292None   L10I, I13V, E35D, M36I, R41K, L63V, C67CY, H69K, V82I, N83X, L89MA
Brumme (2007)1365PRRT_1365EF368675None   I13V, K14R, K20I, M36I, R41K, H69K, V82I, L89MA
Eyzaguirre (2007)KZ30023503KZ300235EF576767None   I13V, K14R, E35D, M36I, R41K, H69K, V82I, L89M, I93LA
Razafindratsimandresy (2007)1111HIV-SEYEF143503None   I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 1212HIV-SEYEF143504None   I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 1313HIV-SEYEF143505None   I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 1717HIV-SEYEF143509None   I13V, K14R, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 1919HIV-SEYEF143511None   I13V, G16A, E35D, M36I, R41K, R57K, I62V, H69K, V75I, V82I, L89MA
 2121HIV-SEYEF143513None   I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 2929HIV-SEYEF143520None   I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
 4343HIV-SEYEF143534None   I13V, G16A, E35D, M36I, R41K, R57K, L63V, H69K, V82I, L89M, I93LA
Nyombi (2008)TBK018TBK018EU251725None   I13V, K20I, E35D, M36I, R41K, R57K, L63P, H69K, I72L, V82I, L89MA
Auwanit (2009)42AE-PR42FJ463518None   K14R, I15IV, L19LQ, E35D, M36I, R41K, I62V, L63ST, H69K, K70R, V82I, L89IA
Vercauteren (2009)pt2162245005610GQ398862None   L10I, T12R, I13V, I15V, L19I, K20I, E35D, M36I, N37D, R41K, H69Q, V82I, L89MA
 pt13395208160299GQ399685None   I13V, K14R, I15V, M36I, R41K, D60E, L63P, C67Y, H69K, V82I, L89M, I93LA
 pt5759510400631GQ400449None   L10I, T12A, I13V, I15K, G16E, K20R, E21D, E35D, M36I, L63A, C67CY, H69K, K70R, V82I, L89MA
Tovanabutra (2010)KECst_028KECst_028FJ623479None   I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
Hamers (2011)CP076301537CP076301537HQ993581None   I13V, E35D, M36I, R41K, R57K, L63PT, H69K, V77I, V82I, L89MA
 CP076301760CP076301760HQ993748None   I13V, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, K70R, V82I, L89M, T91V, I93LA
 CP076304140CP076304140HQ993876None   L10I, I13V, G16A, M36I, R41K, K43R, R57K, L63T, H69KN, K70R, V82I, L89IA
 CP076303076CP076303076HQ995254None   I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89MA
Kasang (2011)13261326HM572420None   I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
Ngo-Giang-Huong (2011)PHPT4352PHPT4352PR-RTHQ996515None   T12A, K14R, I15IV, G16GA, Q18QL, M36D, R41K, H69K, V82I, L89M, I93LA
Afonso (2012)ANG40ANG40JN937053None   E35K, M36I, N37D, R41K, R57K, L63T, H69K, V82I, L89MA
Chen (2012)YN09DH0016YN09DH0016JQ658489None   L10I, I13V, I15V, K20I, E35D, M36I, L63P, H69K, V82I, L89M, I93VA
 YN10DH0085YN10DH0085JQ658706None   I13V, M36I, R41K, I62V, L63P, H69K, K70R, V82I, L89MA
Dvali (2012)R006R006FJ178577None   R8RP, I13V, E35D, M36I, R41K, H69K, V82I, L89M, I93LA
Nazziwa (2012)51191015119101JX499006None   I13V, K14R, E35D, M36I, R41K, R57K, I62V, L63H, H69K, V82I, L89MA
Oliveira (2012)05CVHAN5105CVHAN51JF267456None   T12R, I13V, L19I, M36I, N37D, R41K, R57K, V82I, L89MA
Ssemwanga (2012)3272HR3272HRJF800198None   I13V, K20I, E21K, M36I, R41K, L63N, H69K, V82I, L89MA
Frentz (2013)EHR-07924EHR-07924JX299669None   I13V, I15V, E35D, M36I, R41K, R57K, H69K, V82I, L89MA
Hassan (2013)RS09000931RS09000931HQ441673None   I13V, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, K70R, V82I, L89M, T91V, I93LA
 RS11000320RS11000320JQ698398None   T12P, I13V, G16E, K20R, E35D, M36I, R41K, Q61E, L63V, G68E, H69K, K70R, V82I, L89M, T91V, I93LA
Acharya (2014)DGP049DGP049KJ185219None   I13V, K14R, E35D, M36I, N37D, R41K, R57K, I62V, I64L, H69K, V82I, L89MA
Aghokeng (2014)CM-3-010CM-3-010KC350336None   I13V, I15V, M36I, R41K, L63A, H69K, V82I, L89MA
Lee (2014)MBA1135MBA1135KJ906833None   I13V, K20R, M36I, R41K, R57K, L63P, H69K, V82I, L89MA
 MBA1430MBA1430KJ907113None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
 MBA1029MBA1029KJ906732None   I13V, K14R, K20I, L23LV, E35D, M36I, R41K, H69K, K70KR, V82I, L89MA
 AMU009AMU009KJ906633None   I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82I, L89MA
Budambula (2015)MK38MK38KP792032None   I13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, Q61H, I64M, H69K, I72E, V82I, L89MA
 MK60MK60KP792054None   I13V, M36I, R41K, I62V, H69K, V82I, L89MA
Dauwe (2015)A1_01025A1_01025KT863551None   I15V, E35D, M36I, R41K, R57K, C67E, H69K, V82I, L89MA
Li (2015)SF13G024SF13G024KR188163None   I13V, G16E, K20R, E35D, M36I, R41K, H69K, K70R, V82I, L89M, I93LA
Li (2015)HN13S0009HN13S0009KR823500None   G16E, L19I, E35N, M36I, R41K, L63M, H69K, V82I, L89M, I93LA
Meini (2015)111128111128KM438261None   T12TA, I13V, R41K, H69K, K70R, V77I, V82I, L89MA
Zhang (2015)HZ09S0065HZ09S0065KR106790None   I13V, M36I, R41K, L63A, H69K, P79D, V82I, L89MA
Billings (2016)CO0329V1CO0329V1KX907342None   I13V, K14R, E35D, M36I, R41K, K45R, R57K, L63S, H69K, V82I, L89MA
Boillot (2016)ALO03ALO03KT315948None   T12P, I13V, L19I, E35D, M36I, R57K, L63P, C67Y, H69K, V82I, L89MA
Castley (2016)P098043942P098043942KT228564None   I15V, K20R, E35D, M36I, R41K, I62V, C67E, H69K, V82I, L89MA
Chow (2016)MYNBB014MYNBB014KU535906None   E35D, M36I, R41K, K45R, L63P, H69K, K70R, V82I, L89M, I93L, L97IA
 MYNBB050MYNBB050KU535931None   L10V, T12I, I13V, M36I, R41K, L63P, H69K, K70R, V82I, L89IA
 MYNBB072MYNBB072KU535953None   T12I, I13V, M36I, N37D, R41K, L63P, H69K, K70R, V82I, L89I, I93LA
 MYNBB058MYNBB058KU535939None   T12I, I13V, E35D, M36I, N37D, R41K, L63P, H69K, K70R, V82I, L89I, I93LA
 MYNBB091MYNBB091KU535967None   T12I, I13V, E35D, M36I, N37D, R41K, L63P, H69K, V82I, L89IA
Feng (2016)YNBS01HSYNBS01HSKT625867None   T12S, K14R, I15V, Q18H, L19I, E35D, M36I, R41K, L63P, H69K, V82I, L89M, I93LA
Hattori (2016)C09_110862C09-51110862-1AB865268None   I13V, I15V, E35D, M36I, R41K, K45R, R57K, L63T, H69K, V82I, L89MA
Onsongo (2016)114114KM376206None   D25H, E35D, M36I, N37D, R57K, L63P, H69K, V77I, V82I, L89MA
Otecko (2016)405478405478KX306401None   I13V, K14N, G16E, L19I, E35D, M36I, N37H, R41K, L63N, H69K, I72T, V82I, L89M, T91V, I93LA
 402775402775KX306387None   I13V, K14R, E35D, M36I, N37E, R41K, R57K, C67Y, H69K, K70R, V82I, L89MA
Zhao (2016)LS5566LS5566KT379637None   I13V, G16E, K20R, M36I, I62V, L63S, H69K, K70R, V82I, L89IA