Protease Inhibitors

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Protease Inhibitors

Subtype	A
Gene	PR
Mutation	V82I
Rx	PI-naive
IncludeMixtures	No

References	25
Patients	44
Isolates	44

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	PIMinorDRMs	OtherMut	Subtype
Gibb (2002)	DMG107	107_w-9		None		L10LI, T12S, I13V, L19LS, K20I, E35D, M36I, I64IM, H69K, K70KR, V82I, L89M	A
Pandrea (2002)	IP_96CIRMF62	96CIRMF62	AY140634	None		E35D, M36I, R41K, I62V, C67E, H69K, V82I, L89M	A
Eshleman (2004)	ESH_Pat157	ESH520	AY435296	None		I13V, I15IL, E35D, M36I, N37D, R41K, C67CG, H69K, V82I, L89M	A
Carr (2005)	01NGPL490	01NGPL490	DQ013273	None		L10I, I13V, K14R, K20I, E35Q, M36I, R41K, R57K, L63S, C67E, H69K, V82I, L89M	A
Non-B Workgroup (2005)	TK5001	TK5001		None		L10I, I13V, K14R, E35D, M36I, R41K, R57K, L63T, H69K, V82I, L89M	A
Tee (2005)	04MYKL1748	04_1748	AY904586	None		T12I, H69K, V82I, L89M, I93L	A
Weber (2005)	F54577	F54577	AY677382	None		I13V, K14R, I15V, K20I, E35D, M36I, R41K, H69K, V82I, L89M	A
Vidal (2006)	NV_KIST061	02.KIST061	AM041053	None		L10I, T12P, I13V, L19I, M36I, N37D, R41K, I62V, E65D, H69Q, V82I, L89M	A
Zarandia (2006)	MZ_03GEMZ038	03GEMZ038	DQ205292	None		L10I, I13V, E35D, M36I, R41K, L63V, C67CY, H69K, V82I, N83X, L89M	A
Brumme (2007)	1365	PRRT_1365	EF368675	None		I13V, K14R, K20I, M36I, R41K, H69K, V82I, L89M	A
Eyzaguirre (2007)	KZ300235	03KZ300235	EF576767	None		I13V, K14R, E35D, M36I, R41K, H69K, V82I, L89M, I93L	A
Razafindratsimandresy (2007)	2	2HIV-SEY	EF143494	None		I13V, L19I, E35D, M36I, R41K, R57K, I62V, I64L, H69K, V82I, L89M	A
	11	11HIV-SEY	EF143503	None		I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89M	A
	12	12HIV-SEY	EF143504	None		I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89M	A
	13	13HIV-SEY	EF143505	None		I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89M	A
	17	17HIV-SEY	EF143509	None		I13V, K14R, E35D, M36I, R41K, R57K, H69K, V82I, L89M	A
	19	19HIV-SEY	EF143511	None		I13V, G16A, E35D, M36I, R41K, R57K, I62V, H69K, V75I, V82I, L89M	A
	21	21HIV-SEY	EF143513	None		I13V, L19I, E35D, M36I, R41K, R57K, H69K, V82I, L89M	A
	29	29HIV-SEY	EF143520	None		I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89M	A
	43	43HIV-SEY	EF143534	None		I13V, G16A, E35D, M36I, R41K, R57K, L63V, H69K, V82I, L89M, I93L	A
Nyombi (2008)	TBK018	TBK018	EU251725	None		I13V, K20I, E35D, M36I, R41K, R57K, L63P, H69K, I72L, V82I, L89M	A
Bartolo (2009)	HDP72	01AOHDP72	EU068244	None		L10I, I13V, I15V, R41K, H69Q, I72V, V77I, V82I, L89M	A
	HDP74	01AOHDP74	EU068246	None		L10I, I13V, I15V, M36I, R41K, H69Q, I72M, V77I, V82I, L89M	A
	HDP78	01AOHDP78	EU068248	None		L10I, I13V, R41K, H69Q, I72V, V77I, V82I, L89M	A
	SNS39	01AOSNS39	EU068300	None	V11I	L10I, T12R, I13V, I15V, L19I, M36I, N37D, R41K, H69Q, V82I, L89I	A
Vercauteren (2009)	pt2162	245005610	GQ398862	None		L10I, T12R, I13V, I15V, L19I, K20I, E35D, M36I, N37D, R41K, H69Q, V82I, L89M	A
	pt1399	4864954378	GQ399625	None	V11VI	L10I, I13V, L19V, M36MI, N37S, R41K, I62V, L63LI, H69Q, V82I, L89M	A
	pt575	9510400631	GQ400449	None		L10I, T12A, I13V, I15K, G16E, K20R, E21D, E35D, M36I, L63A, C67CY, H69K, K70R, V82I, L89M	A
Hamers (2010)	300037	CP076300037	HM119631	None		I15V, L19M, K20R, E35D, M36I, R41K, H69K, V82I, L89M	A
Ndembi (2010)	DT2829_05_P1	2829	GQ409610	None		I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89M	A
Tovanabutra (2010)	KECst_028	KECst_028	FJ623479	None		I13V, E35D, M36I, R41K, R57K, H69K, V82I, L89M	A
Yang (2010)	2010693452	2010693452	JQ616891	None	V11I	L10I, T12K, I13V, L19V, M36I, N37D, R41K, I62V, L63A, H69Q, V82I, L89M	A
Hamers (2011)	CP076301537	CP076301537	HQ993581	None		I13V, E35D, M36I, R41K, R57K, L63PT, H69K, V77I, V82I, L89M	A
	CP076301760	CP076301760	HQ993748	None		I13V, G16E, K20R, E35D, M36I, R41K, L63T, G68E, H69K, K70R, V82I, L89M, T91V, I93L	A
	CP076304140	CP076304140	HQ993876	None		L10I, I13V, G16A, M36I, R41K, K43R, R57K, L63T, H69KN, K70R, V82I, L89I	A
	CP076304273	CP076304273	HQ993960	None		L19X, M36I, R41K, H69K, V82I, L89M	A
	CP076303076	CP076303076	HQ995254	None		I13V, K20I, E35D, M36I, R41K, H69K, K70R, V82I, L89M	A
	CP076301887	CP076301887	HQ995366	None		T12A, I13V, K20R, M36I, R41K, I62IV, L63LP, H69K, V82I, L89M	A
Kasang (2011)	1326	1326	HM572420	None		I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89M	A
Hassan (2012)	RS11000320	RS11000320	JQ698398	None		T12P, I13V, G16E, K20R, E35D, M36I, R41K, Q61E, L63V, G68E, H69K, K70R, V82I, L89M, T91V, I93L	A
Reynolds (2012)	A0721	A0721-1	JN652170	None		L10V, T12TA, I13V, K14R, G16E, E35D, M36I, N37D, R41K, H69K, V82I, L89M	A
Sigaloff (2012)	KELKN241	KELKN241	JN628507	None		I13V, R41K, L63A, H69K, V82I, L89I	A
Ssemwanga (2012)	3272HR	3272HR	JF800198	None		I13V, K20I, E21K, M36I, R41K, L63N, H69K, V82I, L89M	A
	8651HR	8651HR	JF800231	None		T12S, I15V, E35D, M36I, N37D, R57K, L63T, H69K, V82I	A

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