<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation V77I
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 10
Isolates 10
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Weber (2003)SIIRIS6I-48AY140815SQV, RTV52  I13V, E35D, M36I, R41K, R57K, H69K, V77I, L89MA
Non-B Workgroup (2005)TK2017TK2017 NFV35  I13V, E35D, M36I, R41K, R57K, H69K, V77I, L89MA
 TK2029TK2029 IDV39  L10I, I13V, K14R, G16GE, E35D, M36I, R41K, K45R, R57K, L63P, H69K, V77I, L89MA
Baxter (2006)48-33163316-30818DQ878217PINAI54A, V82F L10I, T12TK, I13V, G16A, L19LV, K20I, E35N, M36I, R41K, D60E, L63P, H69K, T74S, V77I, L89MA
Thomson (2009)SP_B_005RU_SP_B_005FJ009783RTV, IDV, APV, LPV   K14R, G16GE, E35D, M36I, R41K, H69K, V77I, L89M, I93ILA
 SP_B_051RU_SP_B_051FJ009809DRV4  I13V, I15V, E35D, M36I, R41K, H69K, V77I, L89M, I93LA
Reynolds (2012)J7227J0722-2JN652210LPV   I13V, K20I, A22AV, E35N, M36I, R41K, H69K, V77I, L89MA
Avidor (2013)1756_FN1756_FNKC184227LPV   I13IV, E35D, M36I, N37ND, R41K, H69K, V77I, L89MA
Grossman (2014)14601460KC184186LPV52  I13IV, E35D, M36I, R41K, Q61E, L63P, H69K, V77I, L89M, I93LA
 948948 LPV52  I13V, E35D, M36I, R41K, L63T, H69K, V77I, L89M, I93LA