<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L76V
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 12
Isolates 12
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK2149UK2149AY900859Unknown, LPVNAM46I, L76V, I84VL33I, N83DL10I, I13V, A22V, E35D, M36I, N37D, R41K, K45R, R57K, L63P, A71V, L89IA
Baxter (2006)48-14321432-30818DQ877822PINAM46I, I54V, L76V, V82TL24IL10I, I13A, K20I, E35D, M36I, R41K, Q61H, L63P, H69K, T74S, L89IA
 48-32933293-30722DQ878198PINAM46I, I54V, L76V, V82A, L90MV11IL10I, T12E, I13V, I15V, K20I, E35N, M36I, N37D, R41K, I62V, L63P, H69K, K70KR, A71V, T74S, L89I, T91SA
 48-41534153-30326DQ878387PINAM46I, I54L, L76V, I84VL10FI13V, G16E, K20I, L33L_L, E35D, M36I, R57K, Q61R, L63T, H69K, L89I, T91TSA
Knops (2010)ID1585ID1585-GT2GU271169SQV, NFV, RTV, APV, LPV64I54V, L76V, V82M, L90ML33F, Q58E, G73S, L89VL10V, T12V, I13V, I15V, K20R, E35D, M36I, N37E, R57K, I62IV, L63P, H69KA
Barber (2012)5085750857JQ361664LPV M46I, L76V, I84V L10I, I13V, G16E, M36I, R41K, L63T, H69K, L89MA
Nerrienet (2014)R0712188R0712188JN675747LPV M46I, G48V, I54V, L76V, V82TL89VL10R, I13A, K14R, K20I, E35D, M36I, N37D, R41K, K55N, D60E, L63P, H69K, K70R, A71V, T91A, Q92KA
 R1113090R1113090JN675748LPV M46I, I47V, L76V, I84VL10FI13V, G16Q, L19V, K20I, E35D, M36I, P39S, R41K, K55R, D60E, I66F, H69K, A71AV, L89MA
 T0807129T0807129JN675757LPV M46I, I47V, L76V, V82FQ58EL10I, I13V, G16E, K20I, E35DN, M36I, N37ND, K55R, L63T, I64V, H69K, I72T, L89MA
Diaz (2015)RenG16380RenG16380KT747408PINAM46I, I54V, L76V, V82A L10I, I13V, I15V, G16A, L19IV, K20I, E21Q, E35D, M36I, N37E, R41K, I62V, L63P, I64V, H69K, A71T, T74TSA
Ndahimana Jd Riedel (2016)21412141KT982484LPV M46I, I54V, L76V, I84V L10I, I13A, K14R, I15V, K20I, E35N, M36I, R41K, K45R, K55R, R57K, I66F, H69K, L89I, I93VA
 21402140KT982495LPV M46I, I54V, L76V, V82A L10V, I13V, G16E, K20R, E35D, M36I, R41KT, R57K, L63R, H69K, L89I, T91SA