<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L76V
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 11
Isolates 11
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)UK2149UK2149AY900859Unknown, LPVNAM46I, L76V, I84VL33I, N83DL10I, I13V, A22V, E35D, M36I, N37D, R41K, K45R, R57K, L63P, A71V, L89IA
Baxter (2006)48-41534153-30326DQ878387PINAM46I, I54L, L76V, I84VL10FI13V, G16E, K20I, L33L_L, E35D, M36I, R57K, Q61R, L63T, H69K, L89I, T91TSA
Barber (2012)5085750857JQ361664LPV M46I, L76V, I84V L10I, I13V, G16E, M36I, R41K, L63T, H69K, L89MA
Jones (2012)159797159797JN669961PINAM46I, I54V, L76V, V82AL33LFL10I, I13V, I15IV, G16E, K20M, E35D, M36I, R41K, K55R, R57K, Q61N, A71T, I72R, L89IA
 182090182090JN670599PINAM46I, I54V, L76VL89VK20P, E35N, M36I, N37D, R41K, R57K, Q61N, I62V, L63P, A71T, T74S, V82I, Q92KA
Kouri (2012)CU1737-09CU1737-09JQ585309PINAM46MI, I54V, L76V, V82AL10F, L24I, L33FI13V, N37S, R41K, Q61QH, L63P, H69K, A71V, L89M, I93LA
 CU1124-09CU1124-09JQ585275PINAM46MI, I54V, L76V, V82AL10F, L24I, L33FI13V, N37S, R41K, L63P, H69K, A71V, L89M, I93LA
Thiam (2013)2841-HALD2841-HALDJN673708LPV M46I, L76V, I84VV11I, L89VL10I, I13V, L19P, K20I, E35D, M36I, R41K, I62V, H69K, K70R, A71V, I72IR, P79AS, T91TS, Q92QKA
Steegen (2014)09ZAKS00309ZAKS003KJ176287LPV M46I, I54V, L76V, V82AQ58QER41K, D60E, I62V, L63P, H69K, L89IA
 12ZAKS19512ZAKS195KJ176476LPV M46I, I54V, L76V, V82A Q61QH, I62V, L63V, H69K, T74S, L89M, I93LA
 09ZAKS00109ZAKS001KJ176285LPV M46I, I54V, L76V, V82A R41K, D60E, Q61E, L63P, H69K, L89M, I93LA