<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation A71V
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 18
Isolates 18
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Yahi (2001)NY_M72M72AY010434IDV M46MI, I84V I13V, K20I, E35D, M36I, R41K, L63P, H69K, A71V, L89TA
Vergne (2003)VL00SN69HPD00SN69AJ583752IDV I84VG73SI13V, E35D, M36I, R41K, K45R, R57K, L63P, H69K, A71V, L89TA
Non-B Workgroup (2005)UK2149UK2149AY900859Unknown, LPVNAM46I, L76V, I84VL33I, N83DL10I, I13V, A22V, E35D, M36I, N37D, R41K, K45R, R57K, L63P, A71V, L89IA
 TK5005TK5005 SQV, IDV, RTV, NFV, LPV180G48V, I54T, V82A, L90M L10I, I13V, K14R, G17D, K20R, E34N, E35D, M36I, R41K, R57K, D60E, I62V, L63P, H69K, A71V, L89IA
 PL3403155128 IDV, NFV207M46I, I84VL89VL10I, T12S, I13V, L19V, K20I, E35D, N37D, L63P, I66F, H69K, K70R, A71VA
Weber (2005)M50457M50457AY677433NFV94  L10I, T12S, I13V, K14KR, I15IV, K20I, E35D, M36I, N37S, R41K, K45R, H69K, A71V, L89TA
 89M262689M2626AY677414SQV, NFV, RTV261I54V, L90MF53L, L89VL10I, I13V, K14R, K20I, E35D, M36I, N37E, R41K, R57K, H69K, A71V, T74SA
Baxter (2006)48-50315031-30421DQ878557PINAM46I, I54V, V82AG73SI13V, I15V, K20I, E35D, M36I, Q61H, L63D, H69K, A71V, L89TA
Tee (2006)MYKL185504MYKL1855AY960955LPV I54V, V82FL33I, L89VL10I, I13V, Q18H, A22V, E35D, M36I, N37D, H69K, A71V, I93MA
Kouri (2012)CU2041-09CU2041-09JQ585335PINAM46I, I54VL33I, G73SI13V, K14R, K20I, E35D, M36I, H69K, A71V, T74S, V75I, L89TA
 CU1737-09CU1737-09JQ585309PINAM46MI, I54V, L76V, V82AL10F, L24I, L33FI13V, N37S, R41K, Q61QH, L63P, H69K, A71V, L89M, I93LA
 CU1124-09CU1124-09JQ585275PINAM46MI, I54V, L76V, V82AL10F, L24I, L33FI13V, N37S, R41K, L63P, H69K, A71V, L89M, I93LA
Thiam (2013)2841-HALD2841-HALDJN673708LPV M46I, L76V, I84VV11I, L89VL10I, I13V, L19P, K20I, E35D, M36I, R41K, I62V, H69K, K70R, A71V, I72IR, P79AS, T91TS, Q92QKA
Diaz (2015)RenG13633RenG13633KT744661PINAM46I, I47A, I84V, L90ML10F, V11I, F53L, G73S, L89VI13V, I15V, K20T, E35N, M36I, R41K, K55R, R57K, Q61N, L63P, A71V, T74S, T91S, I93LA
 RenG12430RenG12430KT743458PINAD30N, M46L, I50L, V82AN88DL10V, T12A, I13V, I15S, G16R, K20R, E21Q, E35D, M36I, N37T, R41K, K45R, R57K, Q61N, I62V, L63AD, A71V, I72IV, T74TS, I85IV, Q92QRA
 RenG11829RenG11829KT742857PINAM46I, I47A, I84V, L90MF53LL10Y, I13V, I15V, K20IT, E35DG, M36I, R41K, R57K, Q61N, L63P, A71V, T74S, L89I, I93LA
 RenG12636RenG12636KT743664PINAD30N, V32VI, M46I, I47V, I54LVF53FL, L76LM, N88DL10V, T12IM, I13A, K20T, A22AV, E35N, M36I, N37ND, R41K, K45R, R57K, Q61N, L63C, A71V, T74S, L89T, Q92RA
Abdellaziz (2016)1505115051KT339029PINAV32I, M46I, V82AL10F, K43T, L89VI13V, K20M, M36I, L63P, H69K, A71VA