<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L63V
Rx >= 1 PI
IncludeMixtures No
References 10
Patients 15
Isolates 15
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Gibb (2002)DMG7070_w27 NFV27  I13V, G16E, E35D, M36I, R41K, L63V, G68GE, H69K, L89M, T91V, I93LA
Maguire (2002)SW32381SW32381AY900671APV48M46L, I54L L10I, I13V, K20R, M36I, N37D, R41K, L63V, H69KA
Holguin (2003)SP_LP5SP_LP5AF455604PINA  L10I, I13V, K14R, E35D, M36I, R41K, L63V, H69K, L89MA
Gomez-Carrillo (2004)103396103396AY365678PINAI54V I13V, K20I, E35D, M36I, N37D, R41K, I62V, L63V, I66F, G68E, H69R, L89M, T91VA
 104575104575AY365707PINA  I13V, E35D, M36I, N37D, R41K, L63V, H69K, K70R, L89IM, T91VA
 111780111780AY365851PINA  I13V, E35D, M36I, N37D, R41K, L63V, H69K, K70R, L89M, T91VA
Weber (2005)F76135F76135AY677380RTV65  Q7QH, T12V, K14R, K20R, E21K, E35D, M36I, N37D, R41K, R57K, L63V, H69K, L89MA
 F87084F87084AY677406IDV28  L10I, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63V, H69K, L89MA
Baxter (2006)48-12041204-30709DQ877748PINAM46I, G48Q, I54T, V82FL33F, Q58E, N83DL10V, I13V, G16E, E35D, M36L, P39S, R57K, I62V, L63V, H69K, T74A, L89MA
von Wyl (2007)1345191462EF449882PINA  L10V, I13V, E35D, M36I, R41K, K45R, R57K, L63V, L89MA
Dau (2010)10412A10412AGU582000PINA  L10V, I13V, E35D, M36I, R41K, L63V, I64V, H69KA
Jones (2012)160444160444JN669977PINAI54IVL10F, F53FLI13V, E35D, M36I, N37D, R41K, L63V, H69K, K70R, T74A, L89M, T91VA
 178278178278JN670478PINAI54V, V82VA, L90LML10F, F53LI13V, K20I, E35D, M36I, N37D, R41K, I62V, L63V, H69K, K70R, T74A, L89M, T91VA
 203362203362JN671308PINA  L5LF, L10LP, I13V, G16E, E35D, M36I, R41K, L63V, H69K, L89M, T91VA
Van Zyl (2013)313697KC424232LPV26  G16E, K20KR, E35D, M36I, R41K, I62IV, L63V, I64L, H69K, I72V, L89MA