<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L63S
Rx >= 1 PI
IncludeMixtures No
References 7
Patients 10
Isolates 11
Show mutation frequency as:
Exclude mutations:

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)TK1030TK1030 SQV, RTV, IDV146  L10I, I13V, G16E, E35D, M36I, R41K, R57K, L63S, H69K, L89MA
Weber (2005)F78596F78596AY677480IDV18  L10I, I13V, I15L, K20I, E35D, M36I, L63S, H69K, L89MA
Baxter (2006)48-12541254-30617DQ877779PINAG48VL33F, N83DL10LI, I13V, E35D, M36V, N37NS, P39T, R41K, R57K, L63S, H69K, L89MA
  1254-40601DQ877780PI, RTV, TPV>50 L33FT12A, I13V, E35D, M36IV, P39AT, R41K, R57K, L63S, H69K, L89MA
Van Zyl (2013)O7211935KC423520LPV52  T12P, I13V, I15V, G16E, E35D, M36I, R41RK, D60DE, L63S, H69K, K70R, L89IM, T91V, I93LA
Kolomeets (2014)423423_577KJ870619ATV   E35D, M36I, R41K, L63S, H69K, V77I, L89MA
 323323_458KJ870537ATV M46MIG48R, I54IFE35D, M36I, R41K, L63S, H69K, L89M, I93LA
Zain (2015)MYHIVDR089MYHIVDR089KT281535PINA  L10V, I13V, I15V, M36I, R41RK, L63S, H69K, L89MA
Svard (2017)2nd_50092nd_5009KX775285LPV215  I13V, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89MA
 2nd_50162nd_5016KX775286LPV57  L10V, I13V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63S, H69K, K70R, L89MA
 2nd_50452nd_5045KX775292RTV, ATV10  T12A, I13V, K14KR, E35D, M36I, N37D, R41K, K45R, R57K, L63S, H69K, L89MA