<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L63Q
Rx PI-naive
IncludeMixtures No
References 22
Patients 29
Isolates 30
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Weidle (2001)PW_UG463PW_UG463AF358754None   I13V, E35D, M36I, R41K, L63Q, H69K, L89MA
Non-B Workgroup (2005)PL4985392544 None   L10V, I13V, G16E, E35D, M36I, R41K, K45R, L63Q, H69K, L89IA
Rousseau (2006)Pt6303PS119MB1DQ351238None   L10I, E35D, M36I, R41K, L63Q, H69K, L89MA
Galluzzo (2007)M20520UG_M20520JQ220113None   L10V, I13V, E35D, M36I, R41K, R57RK, L63Q, H69K, K70KR, L89MA
Church (2008)365770P365770PEU380733None   I13V, I15V, E35D, M36I, R41K, R57K, L63Q, H69K, L89MA
 377986-M377986-MEU380741None   I13V, G16E, K20R, E35D, M36I, P39S, R41K, K45R, R57K, L63Q, H69K, L89MA
Matthews (2008)PS119PS119FJ199691None   L10I, E35D, M36I, R41K, L63Q, H69K, L89MA
Hamers (2011)CP076301641CP076301641HQ993787None   T4TP, K14KR, E35D, M36I, R41K, Q61E, L63Q, I64IM, H69K, K70KR, L89MA
 CP076302969CP076302969HQ995054None   L10I, I13V, E35D, M36I, P39S, R41K, K45R, R57K, L63Q, H69K, K70R, L89MA
 CP076300861CP076300861HQ995124None   L10I, I13V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63Q, H69K, L89MA
 CP076301811CP076301811HQ995155None   I13V, G16E, E35D, M36I, P39S, R41K, K45R, R57K, L63Q, H69K, K70R, L89MA
 CP076302050CP076302050HQ995202None  V11VIL10LI, I13V, K14KR, G16E, K20R, E35N, M36I, R41K, I62V, L63Q, H69K, L89MA
Kasang (2011)3264332643HM572380None   T12TP, I13V, K14KR, I15IV, G16GAE, E35D, M36I, R41K, R57K, L63Q, H69K, L89MA
Karlsson (2012)SE_297SE_297JQ698871None   I13V, E35D, M36I, R41K, R57K, L63Q, H69K, L89MA
Mollan (2012)MK180MK180w0 None  Q58EE35D, M36I, R41K, R57K, D60E, Q61E, L63Q, C67E, H69K, L89MA
Reynolds (2012)E7105E7105-0JN652153None   L10LV, I13V, K14KN, G16E, K20KR, E35D, M36I, R41K, K45R, R57K, L63Q, H69K, K70KR, L89MA
  E7105-1JN652186None   L10V, I13V, K14KN, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63Q, I64IM, H69K, K70R, P81PS, L89MA
Kiertiburanakul (2013)R74116R74116KC791335None   L10I, I13V, I15V, A28V, M36I, R41K, G52S, L63Q, I66L, H69QA
Kiptoo (2013)SNH029SNH029KC516975None   I15V, E35D, M36IV, N37D, R57K, L63Q, H69K, L89MA
Lee (2014)MBA1214MBA1214KJ906910None   I13V, I15V, E35D, M36I, R41K, R57K, L63Q, H69K, L89MA
 AMU002AMU002KJ906626None   L10V, I13V, G16E, K20R, E35D, M36I, R41K, R57K, L63Q, E65ED, H69K, L89MA
Bruzzone (2015)HM2213FHM2213FKP889085None   I13V, G16E, K20R, E35D, M36I, R41K, L63Q, H69K, T74A, L89M, T91AA
Dauwe (2015)A1_03057A1_03057KT863561None   L10V, I13V, I15V, G16E, E35D, M36I, R41K, K45R, R57K, L63Q, H69K, L89MA
 A1_03001A1_03001KT863559None   L10IM, I13V, G16E, E35D, M36I, N37Y, R41K, R57K, L63Q, H69KQ, L89MA
Neogi (2015)11KR131111KR1311KP307310None   L10V, I13V, I15V, K20R, E35D, M36I, N37E, R41K, K45R, R57K, L63Q, E65D, H69K, L89MA
Billings (2016)CO6592V5CO6592V5KX907412None   I13V, E35D, M36I, R41K, L63Q, H69K, L89MA
Boillot (2016)VIR61VIR61KT315994None   L10I, I13V, K14R, G16E, K20KR, E35D, M36I, N37D, R41K, R57K, D60E, L63Q, H69K, K70R, L89MA
Hattori (2016)C12_111345C12-51111345-1AB865751None   I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63Q, H69K, L89MA
Li (2016)16981698KT191936None   L10LV, T12P, I13V, K14R, G16E, E35D, M36I, R41K, L63Q, H69K, L89MA
Otecko (2016)421498421498KX306468None   E35D, M36I, N37D, R41K, K55R, R57K, D60E, L63Q, H69K, L89LMA