Protease Inhibitors

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Protease Inhibitors

Subtype	A
Gene	PR
Mutation	L63Q
Rx	PI-naive
IncludeMixtures	No

References	13
Patients	18
Isolates	19

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	PIMinorDRMs	OtherMut	Subtype
Vergne (2000)	LVMP1270	LVMP1270	AJ287032	None		L10V, I13V, G16E, E35D, M36I, R41K, K45R, L63Q, H69K, L89M	A
Weidle (2001)	PW_UG463	PW_UG463	AF358754	None		I13V, E35D, M36I, R41K, L63Q, H69K, L89M	A
Non-B Workgroup (2005)	PL49853	92544		None		L10V, I13V, G16E, E35D, M36I, R41K, K45R, L63Q, H69K, L89I	A
Galluzzo (2007)	M20520	UG_M20520	JQ220113	None		L10V, I13V, E35D, M36I, R41K, R57RK, L63Q, H69K, K70KR, L89M	A
Church (2008)	365770P	365770P	EU380733	None		I13V, I15V, E35D, M36I, R41K, R57K, L63Q, H69K, L89M	A
	377986-M	377986-M	EU380741	None		I13V, G16E, K20R, E35D, M36I, P39S, R41K, K45R, R57K, L63Q, H69K, L89M	A
Matthews (2008)	PS119	PS119	FJ199691	None		L10I, E35D, M36I, R41K, L63Q, H69K, L89M	A
Nyombi (2008)	TBK060	TBK060	EU251751	None		R41K, L63Q, I64V, E65D, H69Y, I72V	A
Aghokeng (2011)	HJ1956	HJ1956	JN639450	None		L10I, I13V, I15V, K20I, E35N, M36I, N37D, R41K, L63Q, H69Q, L89M	A
Charpentier (2011)	67	CP 001 369		None		L10V, I13V, G16E, E35D, M36I, N37DE, R41K, L63Q, H69K, K70R, I72V, L89M	A
Hamers (2011)	CP076301641	CP076301641	HQ993787	None		T4TP, K14KR, E35D, M36I, R41K, Q61E, L63Q, I64IM, H69K, K70KR, L89M	A
	CP076302969	CP076302969	HQ995054	None		L10I, I13V, E35D, M36I, P39S, R41K, K45R, R57K, L63Q, H69K, K70R, L89M	A
	CP076300861	CP076300861	HQ995124	None		L10I, I13V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63Q, H69K, L89M	A
	CP076301811	CP076301811	HQ995155	None		I13V, G16E, E35D, M36I, P39S, R41K, K45R, R57K, L63Q, H69K, K70R, L89M	A
	CP076302050	CP076302050	HQ995202	None	V11VI	L10LI, I13V, K14KR, G16E, K20R, E35N, M36I, R41K, I62V, L63Q, H69K, L89M	A
Kasang (2011)	32643	32643	HM572380	None		T12TP, I13V, K14KR, I15IV, G16GAE, E35D, M36I, R41K, R57K, L63Q, H69K, L89M	A
Karlsson (2012)	SE_297	SE_297	JQ698871	None		I13V, E35D, M36I, R41K, R57K, L63Q, H69K, L89M	A
Reynolds (2012)	E7105	E7105-0	JN652153	None		L10LV, I13V, K14KN, G16E, K20KR, E35D, M36I, R41K, K45R, R57K, L63Q, H69K, K70KR, L89M	A
		E7105-1	JN652186	None		L10V, I13V, K14KN, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63Q, I64IM, H69K, K70R, P81PS, L89M	A

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