<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L63I
Rx PI-naive
IncludeMixtures No
References 29
Patients 37
Isolates 37
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Becker-Pergola (2000)194.793BPG194-793AF177354None   I13V, K14KR, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Eshleman (2001)SE440SE440AF388079None   L10I, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Shafer (2003)A384_27742774aEF548532None   P9X, E35D, M36I, R41K, R57K, I62V, L63I, H69K, L89IM, F99XA
Eshleman (2004)ESH_Pat141ESH445AY435289None   L10I, I13V, K14R, G16GA, E35D, M36I, R41K, R57K, L63I, C67CG, H69K, L89MA
Eshleman (2004)194_793194_793AY444183None   I13V, K14KR, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Carr (2005)03UZ03003UZ030AY845759None   I13V, E35D, M36I, R41K, L63I, H69K, L89M, I93LA
Baker (2007)P0079P0079-160305EF186140None   L10V, I13V, K14R, I15V, G16E, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Church (2008)335346R335346REU380722None   L10I, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Ndembi (2008)IAEM022IAEM022EU306759None   I13V, K14KR, E35D, M36I, N37D, R41K, R57K, L63I, H69K, L89MA
Somi (2008)BG-05-438BG-05-438JQ616946None   I13V, I15V, E35D, M36I, L38C, R41K, R57K, L63I, H69K, L89MA
Thomson (2009)SP_B_033RU_SP_B_033FJ009798None   L10I, K14R, E35D, M36I, N37D, R41K, L63I, H69K, L89M, I93LA
Towler (2010)439552-J439552-JHM037829None   L10I, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89M, F99LA
Hamers (2011)CP076303121CP076303121HQ995296None   L10V, I13V, I15V, E35D, M36I, N37D, R41K, R57K, D60E, L63I, H69K, L89MA
Ndembi (2011)AICPS035AICPS035HQ702682None   L10M, I13V, K14R, I15V, G16E, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Ndase (2012)5016476250164762KC900577None   I13V, G16E, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 5011940250119402KC900574None   I13V, L33V, E35D, M36I, R41K, R57K, D60E, L63I, H69K, L89MA
Sigaloff (2012)KELKN265KELKN265JN628523None   I13V, K20R, E35D, M36I, N37D, R41K, K45R, R57K, L63I, H69K, L89MA
Avi (2013)266266JX431787None   I13V, K14R, E35D, M36I, R41K, L63I, H69K, L89MA
Hassan (2013)RS09000913RS09000913HQ441658None   I13V, K14R, E35D, M36I, R41K, R57K, I62V, L63I, I64M, H69K, L89MA
Kiptoo (2013)KTL070KTL070KC517010None   I13V, I15V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 KAP056KAP056KC516907None   E35D, M36I, N37D, R41K, R57K, L63I, H69K, L89MA
 KTL056KTL056KC517007None   I13V, K20IR, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 SNH068SNH068KC516950None   E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Pircher (2013)B1134B1134JX110321None   I13V, E35D, M36I, R41K, K45R, L63I, H69K, L89MA
Lee (2014)MBA1441MBA1441KJ907123None   L10I, I13V, K20R, E35D, M36I, N37E, R57K, L63I, H69K, L89MA
Meixenberger (2014)03-0025803-00258KJ769823None   I13V, I15V, G16A, E35D, M36I, R41K, L63I, G68E, H69K, K70R, L89M, T91V, I93LA
 07-0101707-01017KJ770548None   I13V, I15V, G16A, E35D, M36I, R41K, I62IV, L63I, G68E, H69K, K70R, L89M, T91V, I93LA
Parczewski (2014)3A_BI103A_BI10KM284224None   L10I, I13V, K14R, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Hora (2015)DEURF10UG016DEURF10UG016KP109493None   L10I, I13V, G16A, E35D, M36I, R41K, R57K, L63I, H69Q, L89MA
Laga (2015)ARM050ARM050KF692172None   E35D, M36I, R41K, L63I, H69K, I72V, L89MA
Billings (2016)KE169579V3KE169579V3KT022360None  L33II13V, K14R, G16E, E35D, M36V, R41K, R57K, L63I, H69K, L89MA
Ndahimana (2016)14251425KU922785None  L33FL10V, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 12231223KU922818None   L10I, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Zeh (2016)2005290_052005290_05KU248656None   E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 0518760_040518760_04KU248632None   E35D, M36I, R41K, R57K, L63I, C67CY, H69K, L89MA
Vahabpour (2017)P-7P-7KX641034None   M36I, R41K, R57K, L63I, E65D, H69K, L89MA
 P-8P-8KX641035None   M36I, R41K, R57K, L63I, E65D, H69K, L89MA