<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L63I
Rx PI-naive
IncludeMixtures No
References 23
Patients 28
Isolates 28
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Becker-Pergola (2000)194.793BPG194-793AF177354None   I13V, K14KR, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Eshleman (2001)SE440SE440AF388079None   L10I, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Shafer (2003)A384_27742774aEF548532None   P9X, E35D, M36I, R41K, R57K, I62V, L63I, H69K, L89IM, F99XA
Eshleman (2004)ESH_Pat141ESH445AY435289None   L10I, I13V, K14R, G16GA, E35D, M36I, R41K, R57K, L63I, C67CG, H69K, L89MA
Eshleman (2004)194_793194_793AY444183None   I13V, K14KR, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Carr (2005)03UZ03003UZ030AY845759None   I13V, E35D, M36I, R41K, L63I, H69K, L89M, I93LA
Marechal (2006)JF_071JF_071DQ443675None   L10I, L19I, E35D, M36I, R41K, K45KR, G51GV, R57K, L63I, I66IM, H69K, I72IM, L89MA
Baker (2007)P0079P0079-160305EF186140None   L10V, I13V, K14R, I15V, G16E, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Church (2008)335346R335346REU380722None   L10I, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Ndembi (2008)IAEM022IAEM022EU306759None   I13V, K14KR, E35D, M36I, N37D, R41K, R57K, L63I, H69K, L89MA
Somi (2008)BG-05-438BG-05-438JQ616946None   I13V, I15V, E35D, M36I, L38C, R41K, R57K, L63I, H69K, L89MA
Thomson (2009)SP_B_033RU_SP_B_033FJ009798None   L10I, K14R, E35D, M36I, N37D, R41K, L63I, H69K, L89M, I93LA
Ndembi (2010)13354D_P113354GQ409556None   I13V, I15V, L19I, E35D, M36I, R41K, R57K, I62V, L63I, I64M, H69K, K70R, L89MA
Sanders-Buell (2010)051H051HGQ477444None   I13V, L19Q, K20R, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 046H046HGQ477447None   I13V, L19Q, K20R, E35D, M36I, R41K, R57K, I62V, L63I, H69K, L89MA
 027H027HGQ477451None   I13V, L19Q, K20R, E35D, M36I, R41K, R57K, I62V, L63I, H69K, L89MA
Towler (2010)439552-J439552-JHM037829None   L10I, I13V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Hamers (2011)CP076303121CP076303121HQ995296None   L10V, I13V, I15V, E35D, M36I, N37D, R41K, R57K, D60E, L63I, H69K, L89MA
Manasa (2011)10050661005066JN665013None   I13V, I15V, E35D, M36I, R41K, K45R, L63I, H69K, L89MA
Ndembi (2011)AICPS035AICPS035HQ702682None   L10M, I13V, K14R, I15V, G16E, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Sigaloff (2012)KELKN265KELKN265JN628523None   I13V, K20R, E35D, M36I, N37D, R41K, K45R, R57K, L63I, H69K, L89MA
Avi (2013)266266JX431787None   I13V, K14R, E35D, M36I, R41K, L63I, H69K, L89MA
Hassan (2013)RS09000913RS09000913HQ441658None   I13V, K14R, E35D, M36I, R41K, R57K, I62V, L63I, I64M, H69K, L89MA
Kiptoo (2013)KTL070KTL070KC517010None   I13V, I15V, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 KAP056KAP056KC516907None   E35D, M36I, N37D, R41K, R57K, L63I, H69K, L89MA
 KTL056KTL056KC517007None   I13V, K20IR, E35D, M36I, R41K, R57K, L63I, H69K, L89MA
 SNH068SNH068KC516950None   E35D, M36I, R41K, R57K, L63I, H69K, L89MA
Pircher (2013)B1134B1134JX110321None   I13V, E35D, M36I, R41K, K45R, L63I, H69K, L89MA