<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L63H
Rx PI-naive
IncludeMixtures No
References 37
Patients 57
Isolates 58
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Eshleman (2002)123793k123793kAF410210None   I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89IA
 144449s144449sAF410242None   I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89MA
Eshleman (2004)ESH_Pat30ESH839AY435379None   I13V, K14R, I15V, K20R, E35D, M36I, N37D, L63H, H69K, K70E, L89MA
Church (2007)839-146276F839EF612164None   I13V, K14R, I15V, K20R, E35D, M36I, N37D, L63H, H69K, K70E, L89MA
Ndembi (2008)IAEM041IAEM041EU306770None   I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89M, I93LA
Nyombi (2008)TBK002TBK002EU251716None   L10LI, I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89MA
 TMS148TMS148EU251837None   I13V, G16E, E35D, M36I, R41K, Q61H, L63H, H69K, I72V, T74S, L89M, I93LA
Steegen (2009)BV113BV113-1EU872133None   L10V, I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, K70R, L89MA
Vercauteren (2009)pt13175288564221GQ399707None   T12P, I13V, K14R, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89MA
Moussa (2010)1062-BAW1HM117934None   L10I, I13V, G16E, E35D, M36I, R41K, K43R, L63H, H69K, I72M, L89MA
Towler (2010)326455-J326455-JHM037846None   T12TA, I13V, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89MA
Avi (2011)090u090uGQ926653None   I13V, K14R, E35D, M36I, R41K, L63H, H69K, V77I, L89MA
Hamers (2011)CP076301534CP076301534HQ993578None   I15V, G16E, L19X, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89IA
 CP076302269CP076302269HQ993829None   L10I, I13V, G16E, E35D, M36I, N37DE, R41K, R57K, L63H, H69K, L89MA
 CP076303114CP076303114HQ995290None   L10V, I13V, G16E, E35D, M36I, R41K, K43R, R57K, L63H, H69K, L89MA
Nazziwa (2012)51191015119101JX499006None   I13V, K14R, E35D, M36I, R41K, R57K, I62V, L63H, H69K, V82I, L89MA
Ndase (2012)5801436258014362KC900704None   T12R, I13V, G16E, E35D, M36I, R41K, I62V, L63H, H69K, L89MA
Hassan (2013)RS09000966RS09000966HQ441704None   L10I, I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, K70R, L89MA
 RS11000253RS11000253JQ698353None   L10LV, K20R, E35D, M36I, N37D, R41K, I62V, L63H, H69K, K70R, L89MA
Kemal (2013)77177717JQ364523None   I13V, K14N, G16E, L19I, K20I, E35D, M36I, K45R, R57K, L63H, H69K, L89MA
Rusine (2013)468H468HKC841710None   L10V, I13V, G16E, E35D, M36I, R41K, R57K, L63H, E65ED, H69K, K70KR, L89MA
  468HKC841711None   L10V, I13V, G16E, K20KI, E35D, M36I, R41K, R57K, L63H, E65ED, H69K, K70KR, L89MA
Sigaloff (2013)JFP103_0JFP103_0JX182011None   L10A, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, K70R, L89MA
Bartolo (2014)09AOHDP25009AOHDP250KF853824None   I13V, G16E, L19I, K20I, E35D, M36I, R41K, R57K, L63H, H69K, K70R, V77I, L89MA
Lee (2014)MBA1269MBA1269KJ906961None   I13V, G16E, K20I, E35D, M36I, P39Q, R41K, L63H, H69K, K70R, V77I, L89MA
 MBA1521MBA1521KJ907194None   I13V, G16E, K20R, E35D, M36I, R41K, R57K, L63H, H69K, L89MA
 MBA1420MBA1420KJ907105None   T12A, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, L89MA
Budambula (2015)MK83MK83KP792077None   I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, L89MA
Laga (2015)AM008AM008KF720941None   I13V, I15V, E35D, M36I, N37D, R41K, L63H, H69K, L89M, I93Y, G94SA
 AM009AM009KF720942None   I13V, I15V, E35D, M36I, N37D, R41K, L63H, H69K, L89M, I93H, G94SA
Meini (2015)109264109264KM438247None   L10I, I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69Q, K70R, L89MA
Neogi (2015)11KR135111KR1351KP307343None   I13V, E35D, M36I, N37E, R41K, R57K, L63H, H69K, L89MA
Billings (2016)KE215154V4KE215154V4KT022400None   T12P, I13V, K14R, G16E, E35D, M36I, N37Q, R41K, K45R, R57K, L63H, C67Y, H69K, L89MA
 KE263806V2KE263806V2KT022361None   L10V, I13V, K14R, G16E, E35D, M36I, N37D, R41K, K45R, R57K, L63H, H69K, K70R, L89MA
Billings (2016)CO0543V2CO0543V2KX907348None   L10V, I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, L89MA
 CO6830V7CO6830V7KX907423None   I13V, E35D, M36I, R41K, R57K, L63H, H69K, L89MA
Chen (2016)PK033PK033KX232623None   I13V, E35D, M36I, R41K, K43R, R57K, L63H, H69K, L89MA
 PK027PK027KX232619None   I13V, E35D, M36I, R41K, R57K, L63H, H69K, K70Q, L89MA
 PK026PK026KX232618None   I13V, K14R, E35D, M36I, R41K, R57K, L63H, H69K, K70Q, L89MA
 PK015PK015KX232608None   I13V, E35D, M36I, R41K, R57K, L63H, H69K, L89MA
 PK014PK014KX232607None   I13V, E35D, M36V, R41K, R57K, L63H, H69K, L89MA
 PK013PK013KX232606None   T12I, I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, L89MA
Gashnikova (2016)Tyumen42Tyumen42KX640152None   E35D, M36I, R41K, Q61E, L63H, H69K, L89M, I93LA
Kityo (2016)JFP103JFP103m0KT348090None   L10A, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, K70R, L89MA
 MBA111MBA111m0KT348195None   I13V, K20R, M36I, R41K, R57K, L63H, H69KA
Ndahimana (2016)10231023KU922827None   L10V, T12V, I13V, G16E, L19V, E35D, M36I, R41K, K45KR, R57K, Q61D, L63H, H69K, L89MA
Otecko (2016)409312409312KX306432None   I13V, K14R, G16E, E35D, M36I, R41K, K45KR, R57K, L63H, H69K, K70R, I72IV, V77I, L89MA
Saeng-Aroon (2016)114894114894LC114955None   L10IV, I13V, G16E, E35D, M36I, R41K, L63H, H69K, K70R, I72V, L89MA
Zeh (2016)3005200_053005200_05KU248738None   E35D, M36I, R41K, L63H, H69K, L89MA
 0517200_040517200_04KU248621None   E35D, M36I, N37D, R41K, R57K, I62V, L63H, H69K, L89MA
Chaplin (2017)NJIH0326NJIH0326MF622877None   L10I, I13V, K14KR, G16E, E35D, M36I, R41K, L63H, H69Q, L89MA
 NJIH0325NJIH0325MF622876None   L10I, I13V, G16E, E35D, M36I, R41K, L63H, H69Q, L89MA
Dow (2017)1428814288KY747345None   L10I, I13V, G16E, L19S, K20R, E35D, M36I, R41K, R57K, L63H, H69T, L89MA
 1756117561KY747382None   L10V, I13V, G16E, K20R, E35D, M36I, P39S, R41K, R57K, I62V, L63H, H69K, K70R, L89MA
Hachiya (2017)C14-51111669LC162225LC162225None   L10I, I13V, G16E, E35D, M36I, R41K, Q61E, L63H, C67Y, H69K, I72V, L89MA
Kityo (2017)JCR081JCR081m0KT347957None   T12I, I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, I72VA
 JCR097JCR097m0KT347972None   I13V, E35D, M36I, R41K, R57K, L63H, H69K, L89MA
Onywera (2017)05006030500603KX790964None  V11II13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, K70R, L89IA