Protease Inhibitors

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Protease Inhibitors

Subtype	A
Gene	PR
Mutation	L63H
Rx	PI-naive
IncludeMixtures	No

References	16
Patients	22
Isolates	22

Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr)	Patient	Isolate	Acc#	PIs	OtherMut	Subtype
Eshleman (2002)	123793k	123793k	AF410210	None	I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89I	A
	144449s	144449s	AF410242	None	I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89M	A
Eshleman (2004)	ESH_Pat30	ESH839	AY435379	None	I13V, K14R, I15V, K20R, E35D, M36I, N37D, L63H, H69K, K70E, L89M	A
K'Aluoch (2005)	OK_TC020504	TC020504	DQ079840	None	I13V, G16GE, R41K, R57K, L63H, I64V	A
Church (2007)	839-146276F	839	EF612164	None	I13V, K14R, I15V, K20R, E35D, M36I, N37D, L63H, H69K, K70E, L89M	A
Derache (2008)	SGO-71	SGO-71	EU330814	None	I13V, L19P, K20I, M36I, R41K, L63H, H69K, L89M	A
Ndembi (2008)	IAEM041	IAEM041	EU306770	None	I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89M, I93L	A
Nyombi (2008)	TBK002	TBK002	EU251716	None	L10LI, I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89M	A
	TMS148	TMS148	EU251837	None	I13V, G16E, E35D, M36I, R41K, Q61H, L63H, H69K, I72V, T74S, L89M, I93L	A
Hawkins (2009)	P671	ZZP671	FJ931165	None	L10I, I13V, I15V, G16E, E35D, M36I, R41K, I62V, L63H, H69K, K70R, L89M	A
Steegen (2009)	BV113	BV113-1	EU872133	None	L10V, I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, K70R, L89M	A
Vercauteren (2009)	pt1317	5288564221	GQ399707	None	T12P, I13V, K14R, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89M	A
Moussa (2010)	10	62-BAW1	HM117934	None	L10I, I13V, G16E, E35D, M36I, R41K, K43R, L63H, H69K, I72M, L89M	A
Towler (2010)	326455-J	326455-J	HM037846	None	T12TA, I13V, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89M	A
Charpentier (2011)	117	CP 001 201		None	M36I, R41K, I62V, L63H, H69K, K70KR, L89M	A
Hamers (2011)	CP076301534	CP076301534	HQ993578	None	I15V, G16E, L19X, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89I	A
	CP076302269	CP076302269	HQ993829	None	L10I, I13V, G16E, E35D, M36I, N37DE, R41K, R57K, L63H, H69K, L89M	A
	CP076301824	CP076301824	HQ994982	None	I13V, G16E, E35D, M36I, R57K, L63H, H69K, K70R, I72V, L89M	A
	CP076303114	CP076303114	HQ995290	None	L10V, I13V, G16E, E35D, M36I, R41K, K43R, R57K, L63H, H69K, L89M	A
Hassan (2012)	RS09000966	RS09000966	HQ441704	None	L10I, I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, K70R, L89M	A
	RS11000253	RS11000253	JQ698353	None	L10LV, K20R, E35D, M36I, N37D, R41K, I62V, L63H, H69K, K70R, L89M	A
Youngpairoj (2012)	cm1657	cm1657	DQ166429	None	T12I, I13V, G16E, K20I, E35N, M36I, N37D, R41K, L63H, H69K, I72E, L89I	A

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