<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L63H
Rx PI-naive
IncludeMixtures No
References 22
Patients 29
Isolates 29
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Eshleman (2002)123793k123793kAF410210None   I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89IA
 144449s144449sAF410242None   I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89MA
Eshleman (2004)ESH_Pat30ESH839AY435379None   I13V, K14R, I15V, K20R, E35D, M36I, N37D, L63H, H69K, K70E, L89MA
K'Aluoch (2005)OK_TC020504TC020504DQ079840None   I13V, G16GE, R41K, R57K, L63H, I64VA
Niama (2006)ARV60ARV60FM164891None   L10I, V11T, I13V, K20I, M36I, R41K, L63H, H69K, L89MA
Church (2007)839-146276F839EF612164None   I13V, K14R, I15V, K20R, E35D, M36I, N37D, L63H, H69K, K70E, L89MA
Derache (2008)SGO-71SGO-71EU330814None   I13V, L19P, K20I, M36I, R41K, L63H, H69K, L89MA
Ndembi (2008)IAEM041IAEM041EU306770None   I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89M, I93LA
Nyombi (2008)TBK002TBK002EU251716None   L10LI, I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89MA
 TMS148TMS148EU251837None   I13V, G16E, E35D, M36I, R41K, Q61H, L63H, H69K, I72V, T74S, L89M, I93LA
Hawkins (2009)P671ZZP671FJ931165None   L10I, I13V, I15V, G16E, E35D, M36I, R41K, I62V, L63H, H69K, K70R, L89MA
Steegen (2009)BV113BV113-1EU872133None   L10V, I13V, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, K70R, L89MA
Vercauteren (2009)pt13175288564221GQ399707None   T12P, I13V, K14R, G16E, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89MA
Moussa (2010)1062-BAW1HM117934None   L10I, I13V, G16E, E35D, M36I, R41K, K43R, L63H, H69K, I72M, L89MA
Towler (2010)326455-J326455-JHM037846None   T12TA, I13V, E35D, M36I, R41K, K45R, R57K, L63H, H69K, L89MA
Charpentier (2011)117CP 001 201 None   M36I, R41K, I62V, L63H, H69K, K70KR, L89MA
Hamers (2011)CP076301534CP076301534HQ993578None   I15V, G16E, L19X, E35D, M36I, R41K, R57K, L63H, H69K, I72V, L89IA
 CP076302269CP076302269HQ993829None   L10I, I13V, G16E, E35D, M36I, N37DE, R41K, R57K, L63H, H69K, L89MA
 CP076301824CP076301824HQ994982None   I13V, G16E, E35D, M36I, R57K, L63H, H69K, K70R, I72V, L89MA
 CP076303114CP076303114HQ995290None   L10V, I13V, G16E, E35D, M36I, R41K, K43R, R57K, L63H, H69K, L89MA
Afonso (2012)ANG44ANG44JN937057None  L33FE35D, M36I, R41K, L63H, H69K, K70R, I72V, V77I, L89MA
Youngpairoj (2012)cm1657cm1657DQ166429None   T12I, I13V, G16E, K20I, E35N, M36I, N37D, R41K, L63H, H69K, I72E, L89IA
Hassan (2013)RS09000966RS09000966HQ441704None   L10I, I13V, G16E, E35D, M36I, R41K, R57K, L63H, H69K, K70R, L89MA
 RS11000253RS11000253JQ698353None   L10LV, K20R, E35D, M36I, N37D, R41K, I62V, L63H, H69K, K70R, L89MA
Kemal (2013)77177717JQ364523None   I13V, K14N, G16E, L19I, K20I, E35D, M36I, K45R, R57K, L63H, H69K, L89MA
Sigaloff (2013)JFP103_0JFP103_0JX182011None   L10A, I13V, K14R, G16E, E35D, M36I, R41K, R57K, L63H, H69K, K70R, L89MA
Bartolo (2014)09AOHDP25009AOHDP250KF853824None   I13V, G16E, L19I, K20I, E35D, M36I, R41K, R57K, L63H, H69K, K70R, V77I, L89MA
Lee (2014)MBA1269MBA1269KJ906961None   I13V, G16E, K20I, E35D, M36I, P39Q, R41K, L63H, H69K, K70R, V77I, L89MA
 MBA1521MBA1521KJ907194None   I13V, G16E, K20R, E35D, M36I, R41K, R57K, L63H, H69K, L89MA