<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation L63A
Rx PI-naive
IncludeMixtures No
References 44
Patients 88
Isolates 89
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Holguin (2000)AHHC17HolgHC17AF188349None   L10I, E35D, M36I, R41K, L63A, C67D, H69K, L89MA
Si-Mohamed (2000)AS_FOGAS_FOGAF199299None   I13V, G16E, E35D, M36I, R41K, L63A, H69K, V77I, L89MA
Gibb (2002)DMG55_w0 None   I13V, E35D, M36I, R41K, R57K, L63A, I64M, H69K, L89MA
Servais (2004)SJ_Pat8SJKLM015AJ412942None   K14R, E35D, M36I, R41K, R57K, L63A, H69K, L89MA
Vessiere (2006)AV_M4606NAV_M4606NDQ297201None   I13V, G16E, G17DE, K20KR, E35D, M36L, R41K, L63A, H69K, K70R, L89M, T91V, I93LA
Vidal (2006)NV_KSFE11002.KSFE110AM041005None   I13V, G16E, K20R, E35D, M36I, P39S, R41K, D60E, I62V, L63A, H69K, L89MA
 NV_KSS00402.KSS004AM041045None   I13V, G16E, K20R, E35D, M36I, R41K, L63A, I64V, H69K, T91V, I93LA
Visawapoka (2006)KNH1239KNH1239AY945739None   I13V, G16E, E35D, M36I, R41K, L63A, H69K, K70R, L89M, T91VA
Dilernia (2007)F038F038EF120099None   I13V, G16E, K20R, E35D, M36I, N37D, R41K, L63A, G68GE, H69KR, L89M, T91V, I93LA
Galluzzo (2007)24080RW_24080JQ220007None   I13V, E35D, M36I, R41K, R57K, L63A, H69K, L89MA
Vidal (2007)U152402BU.U1524AM260313None   I13V, E35D, M36I, R41K, R57K, L63A, H69K, K70R, V77I, L89MA
Holguin (2008)SP1B-118006SP1B-118006EU362920None   L10I, I13V, G16E, E35D, M36I, R41K, L63A, H69K, L89M, T91VA
Ndembi (2008)IAEM067IAEM067EU306786None   I13V, E35D, M36I, N37I, R41K, R57K, L63A, H69K, L89MA
Nyombi (2008)TBK030TBK030EU251733None  V11VIL10I, I13V, K14R, E35D, M36I, R41K, R57K, I62V, L63A, H69K, L89MA
 TMS002TMS002EU251783None   I13V, K14R, E35D, M36I, R41K, R57K, L63A, H69K, K70R, L89MA
 TMS016TMS016EU251795None   I13V, E35D, M36I, R41K, R57K, I62V, L63A, I64L, H69K, L89MA
 TMS108TMS108EU251810None   I13V, K14R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 TMS115TMS115EU251815None   I13V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 TMS127TMS127EU251825None   I13V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 TMS343TMS343EU251877None   L10V, I13V, K14R, G16E, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
Somi (2008)KW-05-010KW-05-010JQ616960None   I13V, K14R, E35D, M36I, R41K, M46X, R57K, L63A, I64M, H69K, L89MA
Aghokeng (2009)AV_0274AV_0274GU191655None   I15V, G16E, E35D, M36I, R41K, R57K, Q61QH, L63A, E65EDA
Bartolo (2009)HAB8701AOHAB87EU068220None   L10V, I13V, G16E, E35D, M36I, R41K, I62V, L63A, H69K, L89MA
Cuevas (2009)X2711_1X2711_1GU326181None   K14R, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89M, I93LA
Vercauteren (2009)pt2176190217330GQ398848None   T12I, I13V, K14R, G16GE, E35D, M36I, R41K, R57K, L63A, H69K, L89MA
 pt17592825916426GQ399265None   Q7QE, I13V, K14R, I15V, K20R, E35D, M36I, N37D, R57K, L63A, H69K, K70R, L89MA
 pt16883214946766GQ399336None   I13V, K14KR, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 pt14454576341374GQ399579None   I13V, K14R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 pt14404619944919GQ399584None   I13V, L19I, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 pt14124784320538GQ399612None   L10LM, I13V, I15IL, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 pt13545089956118GQ399670None   I13V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89M, L97*A
 pt13325234413600GQ399692None   I13V, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89M, I93LA
 pt11066564519905GQ399918None   L10I, I13V, K14R, G16E, K20R, E35D, M36I, N37D, R41K, K45R, R57K, L63A, H69K, K70R, L89MA
 pt8777940838415GQ400147None   I13V, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89M, N98NIA
 pt7598595222384GQ400265None   I13V, L19I, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 pt5759510400631GQ400449None   L10I, T12A, I13V, I15K, G16E, K20R, E21D, E35D, M36I, L63A, C67CY, H69K, K70R, V82I, L89MA
Yebra (2009)SP11-322971SP11-322971EU255384None   I13V, E35D, M36I, R41K, K45KR, L63A, H69K, L89MA
Djoko (2010)677CD2038FR666677None   I13V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 678CD2656FR666678None   I13V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
Mosha (2010)S47PolS47PolJQ071479None   I13V, K14QR, I15V, E35D, M36I, R41K, R57K, L63A, H69K, K70KR, L89MA
Ndembi (2010)16079D_P116079GQ409581None   I13V, K14R, E35D, M36I, R41K, R57K, L63A, H69K, L89MA
Soares (2010)CM04_094CM04_094GU366134None   L10V, I13V, K14R, G16E, K20R, E35D, M36I, R41K, K45R, L63A, H69K, L89MA
Towler (2010)1320024-AHM037810None   T12S, I13V, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
  393250-SHM037884None   L10V, I13V, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 337314-Y337314-YHM037815None   I13V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
Yang (2010)20106934522010693452JQ616891None  V11IL10I, T12K, I13V, L19V, M36I, N37D, R41K, I62V, L63A, H69Q, V82I, L89MA
Charpentier (2011)121CP 001 724 None   I15IV, K20R, E35D, M36I, N37D, R41K, R57K, Y59YH, L63A, H69K, K70R, L89MA
Hamers (2011)CP076301700CP076301700HQ993695None   L10I, I13V, K14R, G16E, E35D, M36I, N37D, R57K, L63A, H69K, L89MA
 CP076301735CP076301735HQ993725None   E35D, M36I, R41K, R57K, L63A, H69K, L89MA
 CP076302168CP076302168HQ994520None   K14R, E35D, M36I, R41K, I62IV, L63A, E65D, H69K, L89MA
 CP076300836CP076300836HQ994955None   I13V, E35D, M36I, R57K, L63A, H69K, L89MA
 CP076300859CP076300859HQ995122None   I13V, E35D, M36I, R41K, R57K, L63A, H69K, L89MA
 CP076301992CP076301992HQ995178None   I13V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, I72V, L89MA
 CP076302069CP076302069HQ995208None   L10I, I13V, E35D, M36I, R41K, K45KR, R57K, L63A, H69K, L89MA
 CP076303090CP076303090HQ995267None   L10V, I13V, E35D, M36I, R41K, K43R, R57K, L63A, H69K, L89MA
 CP076301890CP076301890HQ995369None   L10I, I13V, G16E, E35D, M36I, R41K, R57K, L63A, H69K, K70R, L89MA
 CP076301930CP076301930HQ995398None   I13V, K14R, I15V, K20I, E35D, M36I, R41K, L63A, H69K, V82VI, L89MA
 CP076301955CP076301955HQ995420None   I13V, K14R, K20R, E35D, M36I, N37E, R41K, K45R, R57K, L63A, H69K, L89MA
Kasang (2011)3263932639HM572369None   I13V, K14R, E35D, M36I, R41K, R57K, L63A, H69K, L89MA
 1449614496HM572374None   L10I, I13V, L19LQ, E35D, M36I, R41K, K45R, R57K, L63A, H69Q, N83NS, L89IMA
Ndembi (2011)NTCPS716NTCPS716HQ702631None   I13V, K14R, K20I, E35D, M36I, N37S, R41K, L63A, H69K, K70Q, L89MA
 AICPS005AICPS005HQ702676None   I13V, I15V, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
 UGNTC737UGNTC737HQ702685None   I13V, E35D, M36I, R41K, R57K, L63A, H69K, K70R, L89MA
Caron (2012)Gab014268Gab014268HQ541900None   I13V, E35D, M36I, R41K, K45R, L63A, H69K, L89MA
De Gascun (2012)IRL41912IRL41912JN622360None   I13V, K14R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
Sigaloff (2012)KEKSN410KEKSN410JN628475None   I13V, I15V, G16E, K20R, M36I, R41K, L63A, G68E, H69K, K70R, L89M, T91V, I93LA
 KEKSN413KEKSN413JN628477None   I13V, K14R, I15V, K20R, E35D, M36I, R41K, K45Q, R57K, I62V, L63A, E65D, H69K, L89M, L97VA
 KELKN241KELKN241JN628507None   I13V, R41K, L63A, H69K, V82I, L89IA
 KELKN250KELKN250JN628513None   K14R, I15V, G16A, L19I, E35N, M36V, R41K, R57K, L63A, H69K, L89MA
Ssemwanga (2012)8627HR8627HRJF800230None   I13V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, L89MA
Alencar (2013)SP2-0011SP2-0011JQ237966None   L10I, I13V, E35D, M36I, R41K, K45R, L63A, H69Q, L89MA
Antoniadou (2013)GR128GR128KF671837None   I13V, E35D, M36I, K45R, R57K, L63A, H69K, L89MA
 GR105GR105KF671814None   L10V, I13V, K14R, E35D, M36I, R41K, K45R, R57K, L63A, H69K, K70R, L89MA
Avi (2013)187187JX431736None   I13V, E35D, M36I, R41K, R57K, Q61E, L63A, I64L, H69K, V77I, L89MA
 181181JX431732None   I13V, E35D, M36I, R41K, R57K, Q61E, L63A, I64L, H69K, V77I, L89MA
Avidor (2013)20392039KC184348None   I13V, I15IV, K20KR, E35ED, M36I, N37ND, R41K, Q61E, L63A, I64M, H69K, L89M, I93LA
Billong (2013)MR094MR094KF192217None   L10I, E35D, M36I, R41K, L63A, C67E, H69K, L89MA
Frentz (2013)EHR-11577EHR-11577JX299726None   I13V, E35D, M36I, R57K, I62V, L63A, H69K, I72V, T74S, L89MA
 EHR-50613EHR-50613JX300382None   I13V, E35D, M36I, N37D, R41K, R57K, L63A, H69K, L89MA
Hassan (2013)RS11000252RS11000252JQ698352None   L10I, I13V, K20R, E35D, M36I, N37D, R41K, D60E, L63A, C67Y, H69K, L89MA
 RS11000290RS11000290JQ698377None   I13V, G16E, E35D, M36I, R41K, L63A, H69K, K70R, L89M, T91VA
 RS11000349RS11000349JQ698420None   I13V, K14KR, G16E, K20R, E35D, M36I, R41K, I62V, L63A, G68E, H69K, K70R, L89M, T91V, I93LA
Hawke (2013)2618286 H2618286 HKC238092None   L10V, I13V, E35D, M36I, N37D, R41K, R57K, D60E, L63A, C67Y, H69K, L89MA
Inzaule (2013)496496JQ914045None   I13V, E35D, M36I, N37D, R41K, R57K, L63A, H69K, L89MA
Kiptoo (2013)SNH069SNH069KC516951None   I13V, G16E, E21K, E35D, M36I, R41K, L63A, G68E, H69K, K70R, L89M, T91V, I93LA
 KAP005KAP005KC516918None   L10V, I13V, E35D, M36I, N37D, R41K, R57K, L63A, H69K, L89MA
 KAP046KAP046KC516896None   I13V, G16GE, K20R, E35D, M36I, R41K, K43KR, R57K, L63A, H69K, K70KR, L89MA
Van Zyl (2013)1365944KC424386None   I13V, G16E, K20R, E35D, M36I, R41K, L63A, H69K, K70R, L89M, T91VA
 15522995KC423922None   I3L, L10I, I15V, E35D, M36I, N37E, R41K, R57K, I62V, L63A, H69K, T74A, L89MA