<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Protease Inhibitors

Subtype A
Gene PR
Mutation F53L
Rx >= 1 PI
IncludeMixtures No
References 8
Patients 19
Isolates 20
 
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Sequences matching input query are shown below. Original reference, patient identifier, isolate name, partial treatment histories and accession number are indicated. Complete treatment histories, when available, can be accessed by clicking the isolate name. Sequences may additionally be downloaded in the fasta format, or viewed as individual or composite alignments using the options above. If the user wishes to view individual alignments of isolates for which there are multiple clones, the user can choose to view either an alignment of consensus sequences derived from the clones or an alignment of each clone as well as a consensus sequence.

Author (yr) Patient Isolate Acc# PIs WksPIMajorDRMs PIMinorDRMs OtherMutSubtype
Non-B Workgroup (2005)PL972860099AY901076IDV, RTV, ATV I54V, V82AL33I, F53L, N83DL10Y, I13V, G16E, K20R, A22AV, E35DN, M36I, N37ND, R41RK, L63T, H69K, T74S, L89M, T91AA
Weber (2005)89M262689M2626AY677414SQV, NFV, RTV261I54V, L90MF53L, L89VL10I, I13V, K14R, K20I, E35D, M36I, N37E, R41K, R57K, H69K, A71V, T74SA
Baxter (2006)12-21202120-30715DQ876783PINAM46I, I47V, L90ML10F, L33I, F53L, G73GS, N88G, L89VI13V, K14R, K20T, E35D, M36I, R41K, R57K, I62V, L63P, H69K, A71IA
  2120-40510DQ876754PI, RTV, TPV>43M46I, I47V, L90ML10F, L33I, F53L, G73S, N88G, L89VI13V, K14R, K20T, E35D, M36I, R41K, R57K, I62V, L63P, H69K, A71IA
 48-50215021-30606DQ878555PINAI54V, V82F, I84IV, L90ML33F, F53LL10I, V11L, I13V, I15V, G16E, L19P, K20I, E35N, M36I, K45V, L63T, H69K, L89MA
 48-80538053-30818DQ879078PINAM46L, G48V, I54S, V82AL33I, F53LL10I, I13A, K14N, A22V, E35D, M36I, K55R, R57K, I62V, L63P, H69K, K70KR, T74S, L89IA
Jones (2012)178278178278JN670478PINAI54V, V82VA, L90LML10F, F53LI13V, K20I, E35D, M36I, N37D, R41K, I62V, L63V, H69K, K70R, T74A, L89M, T91VA
Kouri (2012)CU1315-09CU1315-09JQ585290PINAI54V, L90MF53L, L89VI13V, K14R, K20I, E35D, M36I, N37D, R41K, K45R, L63P, C67CY, H69K, A71IA
 CU727-09CU727-09JQ585262PINAG48V, I54V, V82AF53LL10I, I13V, I15V, K20I, E35D, M36I, R41K, I64M, H69K, T74S, L89MA
 CU737-10CU737-10JQ585413PINAV32I, M46I, I47V, L90ML33F, F53L, L89VR8G, I13V, K20T, E35D, M36I, R41K, H69K, G73D, V82IA
Rawizza (2013)LM3929LM3929KF241482LPV M46I, I47V, I54V, V82AF53L, Q58EL10I, I13V, K14R, I15V, K20I, L33L_L, E35G, M36I, R41K, K55R, L63T, I64M, L89MA
Kolomeets (2014)193193_342KJ870451APV I47IVL33F, F53LI13V, I15V, K20T, E35D, M36I, R41K, H69K, V77I, L89MA
Diaz (2015)RenG16883RenG16883KT747911PINAM46IV32A, L33F, F53L, T74TPL10V, I13V, I15V, K20R, E35D, M36I, R41K, R57K, Y59YH, Q61DN, I66F, L89IA
 RenG15692RenG15692KT746720PINAI50L, V82ML33LF, F53LK20T, E35D, M36I, N37NT, P39S, R41K, R57K, D60E, Q61DN, L63C, I72V, T74TA, V77I, L89MA
 RenG13633RenG13633KT744661PINAM46I, I47A, I84V, L90ML10F, V11I, F53L, G73S, L89VI13V, I15V, K20T, E35N, M36I, R41K, K55R, R57K, Q61N, L63P, A71V, T74S, T91S, I93LA
 RenG15167RenG15167KT746195PINAG48M, I54V, V82A, L90MK43T, F53LL10IV, V11L, T12P, I13V, K20I, E35D, M36I, N37K, R41K, R57K, Q61N, L63P, T74S, L89I, Q92KA
 RenG15172RenG15172KT746200PINAV32I, M46I, I47V, I54M, V82A, L90ML33F, F53L, T74PL10I, I13V, G16GDE, K20R, E34A, E35D, M36I, R41K, K45KR, K55R, R57K, Q61N, L63S, C67E, I72V, V77IA
 RenG15076RenG15076KT746104PINAM46I, V82FF53L, N83DW6V, L10V, I13A, A22V, E35D, M36I, R41K, K43R, R57K, Q61N, I62V, L63P, H69R, T74S, L89I, I93LA
 RenG11829RenG11829KT742857PINAM46I, I47A, I84V, L90MF53LL10Y, I13V, I15V, K20IT, E35DG, M36I, R41K, R57K, Q61N, L63P, A71V, T74S, L89I, I93LA
 RenG11119RenG11119KT742147PINAI50LL33LF, F53LG17E, K20R, E35D, M36I, N37DE, R41K, K43R, K45N, R57K, D60N, Q61N, L63T, I72T, V82VI, L89MA